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Original Article

Urinary Excretion of Histamine, Methylhistamine and Methylimidazoleacetic Acids in Man under Standardized Dietary Conditions

Pages 59-68 | Published online: 17 Mar 2010

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Read on this site (10)

Steve L. Taylor & Ronald R. Eitenmiller. (1986) Histamine Food Poisoning: Toxicology and Clinical Aspects. CRC Critical Reviews in Toxicology 17:2, pages 91-128.
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Goran Granerus, Jan Bergmark & John G. Kral. (1979) Histamine metabolism in severe obesity before and after jejuno-ileostomy. Scandinavian Journal of Clinical and Laboratory Investigation 39:7, pages 671-675.
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G. Granerus, B. Gillbrand & H. Wetterqvist. (1977) Histamine Metabolism in Normal Pregnancy and in Toxaemia of Pregnancy. Acta Obstetricia et Gynecologica Scandinavica 56:2, pages 81-86.
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F. Jonassen, H. Wetterqvist & G. Granerus. (1976) Histamine Metabolism and Female Sex Hormones in Women. Acta Obstetricia et Gynecologica Scandinavica 55:5, pages 387-394.
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F. Jonassen, G. Granerus & H. Wetterqvist. (1976) Histamine Metabolism During the Menstrual Cycle. Acta Obstetricia et Gynecologica Scandinavica 55:4, pages 297-304.
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P. Agrup, G. Granerus, S. Jacobsson, H. Wetterqvist & T. White. (1974) Histamine Metabolism in Burn Injuries. Scandinavian Journal of Plastic and Reconstructive Surgery 8:3, pages 198-201.
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J. Bergmark & G. Granerus. (1974) Ion Exchange Chromatography for Quantitative Analysis of Radioactive Histamine Metabolites in Human Urine. Scandinavian Journal of Clinical and Laboratory Investigation 34:4, pages 365-373.
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H. Westling. (1969) Editorial: Evaluation of Histamine Metabolism in Man. Scandinavian Journal of Clinical and Laboratory Investigation 23:1, pages 1-4.
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G. Granerus. (1968) Effects of Oral Histamine, Histidine and Diet on Urinary Excretion of Histamine, Methylhistamine and 1-Methyl-4-imidazoleacetic Acid in Man. Scandinavian Journal of Clinical and Laboratory Investigation 21:sup104, pages 49-58.
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G. Granerus, H. Wetterqvist & T. White. (1968) Histamine Metabolism in Healthy Subjects before and during Treatment with Aminoguanidine. Scandinavian Journal of Clinical and Laboratory Investigation 21:sup104, pages 39-48.
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Articles from other publishers (48)

Chenzhi Hou, Tingting Chu, Mengyi Chen, Zhendong Hua, Peng Xu, Hui Xu, Youmei Wang, Jun Liao & Bin Di. (2021) Application of multi-parameter population model based on endogenous population biomarkers and flow volume in wastewater epidemiology. Science of The Total Environment 759, pages 143480.
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Carolyn D. Keagy. (2018) The potential role of folate metabolism in interstitial cystitis. International Urogynecology Journal 30:3, pages 363-370.
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Phil M. Choi, Jake W. O'Brien, Jiaying Li, Guangming Jiang, Kevin V. Thomas & Jochen F. Mueller. (2018) Population histamine burden assessed using wastewater-based epidemiology: The association of 1,4‑methylimidazole acetic acid and fexofenadine. Environment International 120, pages 172-180.
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Apostolos V Tsolakis. (2015) Histidine decarboxylase and urinary methylimidazoleacetic acid in gastric neuroendocrine cells and tumours. World Journal of Gastroenterology 21:47, pages 13240.
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K. Koutsoumanis, C. Tassou & G.-J. E. Nychas. 2009. Pathogens and Toxins in Foods. Pathogens and Toxins in Foods 248 274 .
K. Shiozaki, T. Nakano, T. Yamaguchi & M. Sato. (2005) Metabolism of exogenous histamine in rainbow trout (Oncorhynchus mykiss). Fish Physiology and Biochemistry 29:4, pages 289-295.
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A. L. Krogstad & G. Roupe. (2001) Microdialysis of histamine in the skin of patients with mastocytosis. Experimental Dermatology 10:2, pages 118-123.
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Granerus LÖnnqvist Nystrand Roupe. (2002) Serum tryptase measured with B12 and G5 antibody‐based immunoassays in mastocytosis patients and its relation to histamine turnover. British Journal of Dermatology 139:5, pages 858-861.
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George D. Prell. 1998. Pharmacology of Endogenous Neurotoxins. Pharmacology of Endogenous Neurotoxins 171 187 .
G. D. Prell, J. K. Khandelwal, R. S. Burns, P. Blandina, A. M. Morrishow & J. P. Green. (1991) Levels ofpros-methylimidazoleacetic acid: Correlation with severity of Parkinson's disease in CSF of patients and with the depletion of striatal dopamine and its metabolites in MPTP-treated mice. Journal of Neural Transmission - Parkinson's Disease and Dementia Section 3:2, pages 109-125.
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C. Maslinski & W. A. Fogel. 1991. Histamine and Histamine Antagonists. Histamine and Histamine Antagonists 165 189 .
George D. Prell & Jack Peter Green. 1991. New Perspectives in Histamine Research. New Perspectives in Histamine Research 343 363 .
G. Granerus, L. Håkansson, G. Roupe & P. Venge. (1989) Serum levels of neutrophil and eosinophil chemotactic activities in mastocytosis. Agents and Actions 27:1-2, pages 208-211.
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E. Oosting, J. J. Keyzer & B. G. Wolthers. (1989) Correlation between urinary levels of histamine metabolites in 24-hour urine and morning urine samples of man: Influence of histamine-rich food. Agents and Actions 27:1-2, pages 205-207.
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G. D. Prell, J. K. Khandelwal, P. A. LeWitt & J. P. Green. (1989) Rostral-caudal concentration gradients of histamine metabolites in human cerebrospinal fluid. Agents and Actions 26:3-4, pages 267-272.
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George D. Prell, Jai K. Khandelwal, Lindsay B. Hough & Jack Peter Green. (1989) pros-Methylimidazoleacetic Acid in Rat Brain: Its Regional Distribution and Relationship to Metabolic Pathways of Histamine. Journal of Neurochemistry 52:2, pages 561-567.
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U. Pipkorn, G. Granerus, D. Proud, A. Kagey‐Sobotka, P. S. Norman, L. M. Lichtenstein & R. M. Naclerio. (2007) The effect of a histamine synthesis inhibitor on the immediate nasal allergic reaction. Allergy 42:7, pages 496-501.
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J. P. Green, G. D. Prell, J. K. Khandelwal & P. Blandina. (1987) Aspects of histamine metabolism. Agents and Actions 22:1-2, pages 1-15.
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M. HOLM‐BENTZEN, I. SØNDERGAARD & T. HALD. (2008) Urinary Excretion of a Metabolite of Histamine (1,4‐methyl‐imidazole‐acetic‐acid) in Painful Bladder Disease. British Journal of Urology 59:3, pages 230-233.
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J. H. Olafsson, O. Lark�, G. Roupe, G. Granerus & U. Bengtsson. (1986) Treatment of chronic urticaria with PUVA or UVA plus placebo: A double-blind study. Archives of Dermatological Research 278:3, pages 228-231.
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K S Herman, R R Bowsher & D P Henry. (1985) Synthesis of N pi-methylhistamine and N alpha-methylhistamine by purified rabbit lung indolethylamine N-methyltransferase.. Journal of Biological Chemistry 260:22, pages 12336-12340.
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G. Granerus, J. H. Olafsson & G. Roupe. (1985) Treatment of two mastocytosis patients with a histidine decarboxylase inhibitor. Agents and Actions 16:3-4, pages 244-248.
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J. J. Keyzer, H. Breukelman, B. G. Wolthers, M. Heuvel, N. Kromme & W. Chr Berg. (1984) Urinary excretion of histamine and some of its metabolites in man: Influence of the diet. Agents and Actions 15:3-4, pages 189-194.
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Göran Granerus & Urban Wass. (1984) Urinary excretion of histamine, methylhistamine (1-MeHi) and methylimidazoleacetic acid (MeImAA) in mastocytosis: Comparison of new HPLC methods with other present methods. Agents and Actions 14:3-4, pages 341-345.
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Göran Granerus, Jon H. Olafsson & Gösta Roupe. (1983) Studies on Histamine Metabolism in Mastocytosis. Journal of Investigative Dermatology 80:5, pages 410-416.
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Göran Granerus, Aleksander Weinfeld & Jan Westin. (1983) Histamine symptoms and histamine metabolism in chronic granulocytic leukaemia. Agents and Actions 13:2-3, pages 251-255.
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Ib Søndergaard. (2007) Quantitative Determination of 1,4‐Methyl‐Imidazoleacetic Acid in Urine by High Performance Liquid Chromatography. Allergy 37:8, pages 581-586.
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J. K. Khandelwal, L. B. Hough & J. P. Green. (1982) Histamine and some of its metabolites in human body fluidsHistamin und einige seiner Metaboliten in menschlichen Körperflüssigkeiten. Klinische Wochenschrift 60:17, pages 914-918.
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M. A. Beaven, A. Robinson-White, N. B. Roderick & G. L. Kauffman. (1982) The demonstration of histamine release in clinical conditions: A review of past and present assay proceduresDer Nachweis von Histaminfreisetzung unter klinischen Bedingungen: Eine Übersicht vergangener und gegenwärtiger Bestimmungsmethoden. Klinische Wochenschrift 60:17, pages 873-881.
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Göran Granerus & Gösta Roupe. (1982) Increased urinary methylimidazoleacetic acid (MelmAA) as an indicator of systemic mastocytosis. Agents and Actions 12:1-2, pages 29-31.
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J.J. Keyzer, B.G. Wolthers, F.A.J. Muskiet, H.F. Kauffman & A. Groen. (1981) Determination of Nτ-methylhistamine in plasma and urine by isotope dilution mass fragmentography. Clinica Chimica Acta 113:2, pages 165-173.
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Göran Granerus, Gösta Roupe & Gunnar Swanbeck. (1981) Decreased Urinary Histamine Metabolite after Successful PUVA Treatment of Urticaria Pigmentosa. Journal of Investigative Dermatology 76:1, pages 1-3.
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O. Löwhagen, G. Granerus & H. Wetterqvist. (2007) Studies on Histamine Metabolism in Allergen‐Induced Asthma. Allergy 35:6, pages 521-529.
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O. Löwhagen, G. Granerus & H. Wetterqvist. (2007) Studies on Histamine Metabolism in Intrinsic Bronchial Asthma. Allergy 34:6, pages 395-404.
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Granerus & J. Bergmark. (1979) Histamine formation from14C-l-histidine in mastocytosis. Agents and Actions 9:1, pages 39-40.
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R. W. Schayer, H. Wetterqvist, Mauricio A. Beaven & Z. Horakova. 1978. Histamine II and Anti-Histaminics. Histamine II and Anti-Histaminics 109 173 .
Jan Westin, Göran Granerus, Aleksander Weinfeld & Hakon Wetterquist. (2009) Histamine Metabolism in Polycythaemia Vera. Scandinavian Journal of Haematology 15:1, pages 45-57.
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Czesŀaw Maśliński. (1975) Histamine and its metabolism in mammals part II: Catabolism of histamine and histamine liberation. Agents and Actions 5:3, pages 183-225.
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Inger Andersson, Ann-Kathrine Granerus, Rudolf Jagenburg & Alvar Svanborg. (2009) Intestinal Decarboxylation of Orally Administered L-dopa. Acta Medica Scandinavica 198:1-6, pages 415-420.
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Elizabeth Evans & P.J. Nicholls. (1973) A method for the gas chromatographic determination of urinary 1,4-methyl-imidazoleacetic acid. Journal of Chromatography A 82:2, pages 394-397.
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Knut Arnet Eliassen. (2008) Effect of Histamine Loading on the Metabolism of 14 C‐Histarnine, Administered Intravenously or Orally, in Domestic Animals (Goat and Pig) . Acta Physiologica Scandinavica 88:3, pages 303-316.
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Knut Arnet Eliassen. (2008) Metabolism of 14 C‐Histamine in Goats and Pigs Treated with Aminoguanidine . Acta Physiologica Scandinavica 88:1, pages 1-7.
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B. BERG, G. GRANERUS, MAJ‐BRITT JOHANSSON, H. WESTLING & T. WHITE. (2012) Histamine formation from 14 C‐ l ‐histidine in man . British Journal of Pharmacology 46:2, pages 270-280.
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K. A. Eliassen. (2008) Metabolism of 14 C‐Histamine in Domestic Animals . Acta Physiologica Scandinavica 81:3, pages 289-299.
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Bertel Berg, Göran Granerus, Håkan Westling & Thomas White. (2009) Urinary Excretion of Histamine and Histamine Metabolites in Leukaemia. Scandinavian Journal of Haematology 8:1, pages 63-68.
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LARS HOLMBERG. (2008) SOLITARY MASTOCYTOMA. Acta Paediatrica 59:5, pages 558-564.
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Eva M. Kovacs & S. Heisler. (1970) Detection and possible role of a chain methylated histamine metabolite(s) in guinea-pig stomach. European Journal of Pharmacology 11:3, pages 349-360.
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. (2012) PROCEEDINGS OF THE BRITISH PHARMACOLOGICAL SOCIETY: 5 th ‐6 th JANUARY, 1970 . British Journal of Pharmacology 38:2.
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