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Scandinavian Journal of Clinical and Laboratory Investigation Volume 52, 1992 - Issue sup210
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Original

Multidisciplinary cycles for protein engineering: Site-directed mutagenesis and X-ray structural studies of aspartic proteinases

J. E. Pitts Laboratory of Molecular Biology, Department of Crystallography, Birkbeck Colleg, London, UK
,
V. Dhanaraj Laboratory of Molecular Biology, Department of Crystallography, Birkbeck Colleg, London, UK
,
C. G. Dealwis Laboratory of Molecular Biology, Department of Crystallography, Birkbeck Colleg, London, UK
,
D. Mantafounis Laboratory of Molecular Biology, Department of Crystallography, Birkbeck Colleg, London, UK
,
P. Nugent Laboratory of Molecular Biology, Department of Crystallography, Birkbeck Colleg, London, UK
,
P. Orprayoon Laboratory of Molecular Biology, Department of Crystallography, Birkbeck Colleg, London, UK
,
J. B. Cooper Laboratory of Molecular Biology, Department of Crystallography, Birkbeck Colleg, London, UK
,
M. Newman Laboratory of Molecular Biology, Department of Crystallography, Birkbeck Colleg, London, UK
&
T. L. Blundell Laboratory of Molecular Biology, Department of Crystallography, Birkbeck Colleg, London, UK
 show all
Pages 39-50 | Published online: 29 Mar 2011

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A. Kumar, S. Grover, J. Sharma & V. K. Batish. (2010) Chymosin and other milk coagulants: sources and biotechnological interventions. Critical Reviews in Biotechnology 30:4, pages 243-258.
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V. Kairisto & A. Poola. (1995) Software for illustrative presentation of basic clinical characteristics of laboratory tests - GraphROC for Windows. Scandinavian Journal of Clinical and Laboratory Investigation 55:sup222, pages 43-60.
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Articles from other publishers (12)

Patrick F. Fox, Timothy P. Guinee, Timothy M. Cogan & Paul L. H. McSweeneyPatrick F. Fox, Timothy P. Guinee, Timothy M. Cogan & Paul L. H. McSweeney. 2017. Fundamentals of Cheese Science. Fundamentals of Cheese Science 185 229 .
Takashi Kageyama. (2006) Roles of Tyr 13 and Phe 219 in the Unique Substrate Specificity of Pepsin B . Biochemistry 45:48, pages 14415-14426.
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J.E. Pitts, P. Orprayoon, P. Nugent, R.V. Dhanaraj, J.B. Cooper, T.L. Blundell, J. Uusitalo & M. Penttilä. 2005. Biochemistry of Milk Products. Biochemistry of Milk Products 72 82 .
Ruijin Yang, Si-Quan Li & Q. Howard Zhang. (2004) Effects of Pulsed Electric Fields on the Activity and Structure of Pepsin. Journal of Agricultural and Food Chemistry 52:24, pages 7400-7406.
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Takashi Kageyama. (2004) Role of S‘1 Loop Residues in the Substrate Specificities of Pepsin A and Chymosin. Biochemistry 43:48, pages 15122-15130.
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M.J.C. Crabbe. 2004. General Aspects. General Aspects 19 45 .
Luis Alberto Campos & Javier Sancho. (2003) The active site of pepsin is formed in the intermediate conformation dominant at mildly acidic pH. FEBS Letters 538:1-3, pages 89-95.
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Hongjie Chen, Guobao Zhang, Yuying Zhang, Yicheng Dong & Kaiyu Yang. (2000) Functional Implications of Disulfide Bond, Cys206−Cys210, in Recombinant Prochymosin (Chymosin). Biochemistry 39:40, pages 12140-12148.
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Kohji Murakami, Kyoko Takeuchi, Teruhiko Beppu & Sueharu Horinouch. (1998) Structure of asparagine-linked oligosaccharides of an aspartic proteinase from the zygomycete fungus Rhizomucor pusillus. Microbiology 144:5, pages 1369-1374.
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P. F. Fox & P. L. H. McSweeney. 1997. Microbiology and Biochemistry of Cheese and Fermented Milk. Microbiology and Biochemistry of Cheese and Fermented Milk 1 49 .
Timothy J. Cottrell, Linda J. Harris, Takuji Tanaka & Rickey Y. Yada. (1995) The Sole Lysine Residue in Porcine Pepsin Works As a Key Residue for Catalysis and Conformational Flexibility. Journal of Biological Chemistry 270:34, pages 19974-19978.
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Viviane Valverde, Pascal Delmas, Mourad Kaghad, Gérard Loison & Patrick Jara. (1995) Secretion and Maturation Study of Endothiapepsin in Saccharomyces cerevisiae. A FIRST STEP TOWARD IMPROVING ITS SUBSTRATE SPECIFICITY. Journal of Biological Chemistry 270:26, pages 15821-15826.
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