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Scandinavian Journal of Clinical and Laboratory Investigation Volume 56, 1996 - Issue sup226
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Original Article

Novel pathways for elimination of cholesterol by extrahepatic formation of side-chain oxidized oxysterols

Ulf Diczfalusy Division of Clinical Chemistry, Karolinska Institute, Huddinge Hospital, Sweden
,
Erik Lund Division of Clinical Chemistry, Karolinska Institute, Huddinge Hospital, Sweden
,
Dieter Lötjohann Division of Clinical Chemistry, Karolinska Institute, Huddinge Hospital, Sweden
&
Ingemar Björkhem Division of Clinical Chemistry, Karolinska Institute, Huddinge Hospital, Sweden
Pages 9-17 | Published online: 17 Mar 2010

Citations (22)

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Read on this site (1)

Christophe Garenc, Pierre Julien & Emile Levy. (2010) Oxysterols in biological systems: The gastrointestinal tract, liver, vascular wall and central nervous system. Free Radical Research 44:1, pages 47-73.
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Articles from other publishers (21)

Kelly Fellows Maxwell, Sonia Bhattacharya, Mary Lou Bodziak, Dejan Jakimovski, Jesper Hagemeier, Richard W. Browne, Bianca Weinstock-Guttman, Robert Zivadinov & Murali Ramanathan. (2019) Oxysterols and apolipoproteins in multiple sclerosis: a 5 year follow-up study. Journal of Lipid Research 60:7, pages 1190-1198.
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Anna-Maria Caridis, Richard J. Lightbody, Jamie M.R. Tarlton, Sharron Dolan & Annette Graham. (2019) Genetic obesity increases pancreatic expression of mitochondrial proteins which regulate cholesterol efflux in BRIN-BD11 insulinoma cells. Bioscience Reports 39:3.
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Lucía Baila-Rueda, Itziar Lamiquiz-Moneo, Estíbaliz Jarauta, Rocío Mateo-Gallego, Sofía Perez-Calahorra, Victoria Marco-Benedí, Ana M. Bea, Ana Cenarro & Fernando Civeira. (2018) Association between non-cholesterol sterol concentrations and Achilles tendon thickness in patients with genetic familial hypercholesterolemia. Journal of Translational Medicine 16:1.
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Tejal K. Patel, Vandana B. Patel & Digvijay G. Rana. (2017) Possible anti-depressant effect of efavirenz and pro-depressive-like effect of voriconazole in specified doses in various experimental models of depression in mice. Pharmacological Reports 69:5, pages 1082-1087.
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Nhan Tram & Pui Ee. (2017) Macromolecular Conjugate and Biological Carrier Approaches for the Targeted Delivery of Antibiotics. Antibiotics 6:3, pages 14.
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Hans-Frieder Schött, Sabine Baumgartner, Constanze Husche, Alexandra Luister, Silvia Friedrichs, Charlotte M. Miller, Florence O. McCarthy, Jogchum Plat, Ulrich Laufs, Oliver Weingärtner & Dieter Lütjohann. (2017) Oxidation of sitosterol and transport of its 7-oxygenated products from different tissues in humans and ApoE knockout mice. The Journal of Steroid Biochemistry and Molecular Biology 169, pages 145-151.
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Hans-Frieder Schött, Constanze Husche, Silvia Friedrichs, Charlotte M. Miller, Florence O. McCarthy, Ulrich Laufs, Jogchum Plat, Oliver Weingärtner & Dieter Lütjohann. (2015) 7β-Hydroxysitosterol crosses the blood–brain barrier more favored than its substrate sitosterol in ApoE−/− mice. Steroids 99, pages 178-182.
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Yu. V. Ermolovich, V. N. Zhabinskii & V. A. Khripach. (2015) Formation of the steroidal C-25 chiral center via the asymmetric alkylation methodology. Organic & Biomolecular Chemistry 13:3, pages 776-782.
Crossref
Gérard Lizard. (2014) Highlight on transient activation of red/ox-dependent survival signals involving MEK/ERK and PI3/Akt signaling pathways in 27-hydroxycholesterol treated-U937 Human monocytic cells: Commentary on “Survival signaling elicited by 27-hydroxycholesterol through the combined modulation of cellular redox state and ERK/Akt phosphorylation,” by Beyza Vurusaner et al.. Free Radical Biology and Medicine 77, pages 386-387.
Crossref
Nuno Vale, Maria João Gouveia, Mónica Botelho, Banchob Sripa, Sutas Suttiprapa, Gabriel Rinaldi, Paula Gomes, Paul J. Brindley & José Manuel Correia da Costa. (2013) Carcinogenic liver fluke Opisthorchis viverrini oxysterols detected by LC–MS/MS survey of soluble fraction parasite extract. Parasitology International 62:6, pages 535-542.
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Apinya Jusakul, Puangrat Yongvanit, Watcharin Loilome, Nisana Namwat & Rahul Kuver. (2011) Mechanisms of oxysterol-induced carcinogenesis. Lipids in Health and Disease 10:1.
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A. V. Antonchick, V. N. Zhabinskii & V. A. Khripach. (2007) Oxysterols: Genesis and basic functions. Russian Journal of Bioorganic Chemistry 33:3, pages 275-287.
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G.S. Tint, Hongwei Yu, Quan Shang, Guorong Xu & Shailendra B. Patel. (2006) The use of the Dhcr7 knockout mouse to accurately determine the origin of fetal sterols. Journal of Lipid Research 47:7, pages 1535-1541.
Crossref
Yanxia Ning, Sifeng Chen, Xiaobo Li, Yongjie Ma, Fengdi Zhao & Lianhua Yin. (2006) Cholesterol, LDL, and 25-hydroxycholesterol regulate expression of the steroidogenic acute regulatory protein in microvascular endothelial cell line (bEnd.3). Biochemical and Biophysical Research Communications 342:4, pages 1249-1256.
Crossref
Maura Heverin, Steve Meaney, Dieter Lütjohann, Ulf Diczfalusy, John Wahren & Ingemar Björkhem. (2005) Crossing the barrier: net flux of 27-hydroxycholesterol into the human brain. Journal of Lipid Research 46:5, pages 1047-1052.
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Yann Gueguen, Luc Ferrari & Anne-Marie Batt. (2004) Mécanismes des hyperlipidémies dues aux immunosuppresseurs. Therapies 59:4, pages 463-469.
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E. Hall, P. Hylemon, Z. Vlahcevic, D. Mallonee, K. Valerie, N. Avadhani & W. Pandak. (2001) Overexpression of CYP27 in hepatic and extrahepatic cells: role in the regulation of cholesterol homeostasis. American Journal of Physiology-Gastrointestinal and Liver Physiology 281:1, pages G293-G301.
Crossref
George J. SchroepferJr.Jr.. (2000) Oxysterols: Modulators of Cholesterol Metabolism and Other Processes. Physiological Reviews 80:1, pages 361-554.
Crossref
Laura Liscum & Natalie J Munn. (1999) Intracellular cholesterol transport. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1438:1, pages 19-37.
Crossref
Irina A. Pikuleva, Amir Babiker, Michael R. Waterman & Ingemar Björkhem. (1998) Activities of Recombinant Human Cytochrome P450c27 (CYP27) Which Produce Intermediates of Alternative Bile Acid Biosynthetic Pathways. Journal of Biological Chemistry 273:29, pages 18153-18160.
Crossref
Geoffrey D. Brown. (1998) The biosynthesis of steroids and triterpenoids. Natural Product Reports 15:6, pages 653.
Crossref

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