113
Views
80
CrossRef citations to date
0
Altmetric
Research Article

Short-term Administration of Glucagon-like Peptide-2. Effects on Bone Mineral Density and Markers of Bone Turnover in Short-Bowel Patients with No Colon

Pages 392-398 | Published online: 08 Jul 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

Cheng T Tee, Katharina Wallis & Simon M Gabe. (2011) Emerging treatment options for short bowel syndrome: potential role of teduglutide. Clinical and Experimental Gastroenterology 4, pages 189-196.
Read now
Ida B. Gottschalck, Palle B. Jeppesen, Bolette Hartmann, Jens J. Holst & Dennis B. Henriksen. (2008) Effects of treatment with glucagon-like peptide-2 on bone resorption in colectomized patients with distal ileostomy or jejunostomy and short-bowel syndrome. Scandinavian Journal of Gastroenterology 43:11, pages 1304-1310.
Read now
Ida B. Gottschalck, Palle B. Jeppesen, Jens J. Holst & Dennis B. Henriksen. (2008) Reduction in bone resorption by exogenous glucagon-like peptide-2 administration requires an intact gastrointestinal tract. Scandinavian Journal of Gastroenterology 43:8, pages 929-937.
Read now

Articles from other publishers (77)

Bhaskar Pal & Moitreyee Chattopadhyay. (2024) Recent clinical and pharmacological advancements of incretin-based therapy and the effects of incretin on physiology. Journal of Diabetology 15:1, pages 24-37.
Crossref
Asif Ali, Peter R Flatt & Nigel Irwin. (2024) Gut-Derived Peptide Hormone Analogues and Potential Treatment of Bone Disorders in Obesity and Diabetes Mellitus. Clinical Medicine Insights: Endocrinology and Diabetes 17.
Crossref
Sarina Gadgaard, Johanne A. Windeløv, Sine P. Schiellerup, Jens J. Holst, Bolette Hartmann & Mette M. Rosenkilde. (2023) Long-acting agonists of human and rodent GLP-2 receptors for studies of the physiology and pharmacological potential of the GLP-2 system. Biomedicine & Pharmacotherapy 160, pages 114383.
Crossref
Henrik Maagensen, Mads M. Helsted, Lærke S. Gasbjerg, Tina Vilsbøll & Filip K. Knop. (2022) The Gut-Bone Axis in Diabetes. Current Osteoporosis Reports 21:1, pages 21-31.
Crossref
Qiu Yang, Bing Fu, Dan Luo, Haibo Wang, Hongyi Cao, Xiang Chen, Li Tian & Xijie Yu. (2022) The Multiple Biological Functions of Dipeptidyl Peptidase-4 in Bone Metabolism. Frontiers in Endocrinology 13.
Crossref
Mitsuru Muto, Tatsuru Kaji, Shun Onishi, Keisuke Yano, Waka Yamada & Satoshi Ieiri. (2021) An overview of the current management of short-bowel syndrome in pediatric patients. Surgery Today 52:1, pages 12-21.
Crossref
Giulia Cantini, Martina Trabucco, Ilaria Dicembrini, Edoardo Mannucci & Michaela Luconi. 2020. Hormonal Signaling in Biology and Medicine. Hormonal Signaling in Biology and Medicine 361 381 .
Ziru Li, Julie Hardij, Simon S. Evers, Chelsea R. Hutch, Sarah M. Choi, Yikai Shao, Brian S. Learman, Kenneth T. Lewis, Rebecca L. Schill, Hiroyuki Mori, Devika P. Bagchi, Steven M. Romanelli, Ki-Suk Kim, Emily Bowers, Cameron Griffin, Randy J. Seeley, Kanakadurga Singer, Darleen A. Sandoval, Clifford J. Rosen & Ormond A. MacDougald. (2019) G-CSF partially mediates effects of sleeve gastrectomy on the bone marrow niche. Journal of Clinical Investigation 129:6, pages 2404-2416.
Crossref
Sine Paasch Schiellerup, Kirsa Skov-Jeppesen, Johanne Agerlin Windeløv, Maria Saur Svane, Jens Juul Holst, Bolette Hartmann & Mette Marie Rosenkilde. (2019) Gut Hormones and Their Effect on Bone Metabolism. Potential Drug Therapies in Future Osteoporosis Treatment. Frontiers in Endocrinology 10.
Crossref
Narattaphol Charoenphandhu, Panan Suntornsaratoon, Piangkwan Sa-Nguanmoo, Pongpan Tanajak, Jarinthorn Teerapornpuntakit, Ratchaneevan Aeimlapa, Nipon Chattipakorn & Siriporn Chattipakorn. (2018) Dipeptidyl Peptidase-4 Inhibitor, Vildagliptin, Improves Trabecular Bone Mineral Density and Microstructure in Obese, Insulin-Resistant, Pre-diabetic Rats. Canadian Journal of Diabetes 42:5, pages 545-552.
Crossref
Patricia L. Brubaker. 2011. Comprehensive Physiology. Comprehensive Physiology 1185 1210 .
Yinqiu Yang, Chenhe Zhao, Jing Liang, Mingxiang Yu & Xinhua Qu. (2017) Effect of Dipeptidyl Peptidase-4 Inhibitors on Bone Metabolism and the Possible Underlying Mechanisms. Frontiers in Pharmacology 8.
Crossref
Shengxian Fan, Xiaodong Ni, Jian Wang, Yongliang Zhang, Shen Tao, Wencheng Kong, Yousheng Li & Jieshou Li. (2016) High Prevalence of Suboptimal Vitamin D Status and Bone Loss in Adult Short Bowel Syndrome Even After Weaning Off Parenteral Nutrition. Nutrition in Clinical Practice 32:2, pages 258-265.
Crossref
Walter Ramsey & Carlos M. Isales. 2017. Understanding the Gut-Bone Signaling Axis. Understanding the Gut-Bone Signaling Axis 13 33 .
Stanley J. Dudrick, Jose M. Pimiento & Rifat Latifi. 2017. Surgery of Complex Abdominal Wall Defects. Surgery of Complex Abdominal Wall Defects 225 241 .
Lorenzo Glorie, Patrick C. D'Haese & Anja Verhulst. (2016) Boning up on DPP4, DPP4 substrates, and DPP4-adipokine interactions: Logical reasoning and known facts about bone related effects of DPP4 inhibitors. Bone 92, pages 37-49.
Crossref
Robert E. Carroll, Enrico Benedetti, Joseph P. Schowalter & Alan L. Buchman. (2016) Management and Complications of Short Bowel Syndrome: an Updated Review. Current Gastroenterology Reports 18:7.
Crossref
Farokh R. Demehri, Siddartha Simha, Lauren Stephens, Mary B. Harris, Meghan A. Arnold, Pamela I. Brown & Daniel H. Teitelbaum. (2015) Pediatric intestinal failure: Predictors of metabolic bone disease. Journal of Pediatric Surgery 50:6, pages 958-962.
Crossref
Daniel L. Chan. 2015. Nutritional Management of Hospitalized Small Animals. Nutritional Management of Hospitalized Small Animals 152 158 .
Matthew L. Bechtold, Stephen A. McClave, Lena B. Palmer, Douglas L. Nguyen, Lindsay M. Urben, Robert G. Martindale & Ryan T. Hurt. (2014) The Pharmacologic Treatment of Short Bowel Syndrome: New Tricks and Novel Agents. Current Gastroenterology Reports 16:7.
Crossref
Gustavo Gross Belchior, Mari Cleide Sogayar & Tracy Cannon Grikscheit. (2014) Stem cells and biopharmaceuticals: Vital roles in the growth of tissue-engineered small intestine. Seminars in Pediatric Surgery 23:3, pages 141-149.
Crossref
Daniel J. DruckerBernardo Yusta. (2014) Physiology and Pharmacology of the Enteroendocrine Hormone Glucagon-Like Peptide-2. Annual Review of Physiology 76:1, pages 561-583.
Crossref
Alfonso Vidal Casariego, María Dolores Ballesteros Pomar & Isidoro Cano Rodríguez. 2014. El hueso en las enfermedades endocrinas y nutricionales. El hueso en las enfermedades endocrinas y nutricionales 261 268 .
M. Dibb, A. Teubner, V. Theis, J. Shaffer & S. Lal. (2013) Review article: the management of long‐term parenteral nutrition. Alimentary Pharmacology & Therapeutics 37:6, pages 587-603.
Crossref
Alan L. Buchman. (2012) Teduglutide and Short Bowel Syndrome: Every Night Without Parenteral Fluids Is a Good Night. Gastroenterology 143:6, pages 1416-1420.
Crossref
Victor Uko, Kadakkal Radhakrishnan & Naim Alkhouri. (2012) Short Bowel Syndrome in Children. Pediatric Drugs 14:3, pages 179-188.
Crossref
Zeina M. Nabhan & Linda A. DiMeglio. 2012. Pediatric Metabolic Syndrome. Pediatric Metabolic Syndrome 183 198 .
Jessica L. Costa, Dorit Naot, Jian-Ming Lin, Maureen Watson, Karen E. Callon, Ian R. Reid, Andrew B. Grey & Jillian Cornish. (2011) Ghrelin is an Osteoblast Mitogen and Increases Osteoclastic Bone Resorption In Vitro. International Journal of Peptides 2011, pages 1-7.
Crossref
Kimberly A. Kyle, Thomas L. Willett, Laurie L. Baggio, Daniel J. Drucker & Marc D. Grynpas. (2011) Differential Effects of PPAR-γ Activation versus Chemical or Genetic Reduction of DPP-4 Activity on Bone Quality in Mice. Endocrinology 152:2, pages 457-467.
Crossref
Elda L Pacheco-Pantoja, Lakshminarayan R Ranganath, James A Gallagher, Peter JM Wilson & William D Fraser. (2011) Receptors and effects of gut hormones in three osteoblastic cell lines. BMC Physiology 11:1, pages 12.
Crossref
Jennifer S. Walsh & Dennis B. Henriksen. (2010) Feeding and bone. Archives of Biochemistry and Biophysics 503:1, pages 11-19.
Crossref
X.F. Hu, Y.M. Guo, B.Y. Huang, S. Bun, L.B. Zhang, J.H. Li, D. Liu, F.Y. Long, X. Yang & P. Jiao. (2010) The effect of glucagon-like peptide 2 injection on performance, small intestinal morphology, and nutrient transporter expression of stressed broiler chickens. Poultry Science 89:9, pages 1967-1974.
Crossref
Francisco J. A. de Paula & Clifford J. Rosen. (2010) Obesity, diabetes mellitus and last but not least, osteoporosis. Arquivos Brasileiros de Endocrinologia & Metabologia 54:2, pages 150-157.
Crossref
Monica H. Wojcik, Erinne Meenaghan, Elizabeth A. Lawson, Madhusmita Misra, Anne Klibanski & Karen K. Miller. (2010) Reduced amylin levels are associated with low bone mineral density in women with anorexia nervosa. Bone 46:3, pages 796-800.
Crossref
Mark E. McMellen, Derek Wakeman, Shannon W. Longshore, Lucas A. McDuffie & Brad W. Warner. (2010) Growth factors: possible roles for clinical management of the short bowel syndrome. Seminars in Pediatric Surgery 19:1, pages 35-43.
Crossref
Jillian Cornish, Jessica L Costa & Dorit Naot. (2009) The bone-fat mass relationship: Laboratory studies. IBMS BoneKEy 6:9, pages 311-322.
Crossref
Katharina Wallis, Julian RF Walters & Simon Gabe. (2009) Short bowel syndrome: the role of GLP-2 on improving outcome. Current Opinion in Clinical Nutrition & Metabolic Care 12:5, pages 526-532.
Crossref
J. S. Walsh & R. Eastell. (2009) Effects of Feeding on Bone Metabolism. Clinical Reviews in Bone and Mineral Metabolism 7:3, pages 230-239.
Crossref
Lucia Pacifico, Caterina Anania, Eleonora Poggiogalle, John F. Osborn, Giancarlo Prossomariti, Francesco Martino & Claudio Chiesa. (2009) Relationships of acylated and des-acyl ghrelin levels to bone mineralization in obese children and adolescents. Bone 45:2, pages 274-279.
Crossref
P. B. Jeppesen, P. Lund, I. B. Gottschalck, H. B. Nielsen, J. J. Holst, J. Mortensen, S. S. Poulsen, B. Quistorff & P. B. Mortensen. (2009) Short Bowel Patients Treated for Two Years with Glucagon-Like Peptide 2: Effects on Intestinal Morphology and Absorption, Renal Function, Bone and Body Composition, and Muscle Function. Gastroenterology Research and Practice 2009, pages 1-12.
Crossref
I. R. Reid. (2007) Relationships between fat and bone. Osteoporosis International 19:5, pages 595-606.
Crossref
Prue M Pereira‐Fantini, Eva S Nagy, Sarah L Thomas, Russell G Taylor, Magdy Sourial, Monique CJ Paris, Jens J Holst, Peter J Fuller & Julie E Bines. (2008) GLP‐2 Administration Results in Increased Proliferation but Paradoxically an Adverse Outcome in a Juvenile Piglet Model of Short Bowel Syndrome. Journal of Pediatric Gastroenterology and Nutrition 46:1, pages 20-28.
Crossref
Marco Di Monaco, Fulvia Vallero, Roberto Di Monaco, Rosa Tappero & Alberto Cavanna. (2007) Skeletal muscle mass, fat mass, and hip bone mineral density in elderly women with hip fracture. Journal of Bone and Mineral Metabolism 25:4, pages 237-242.
Crossref
Andrew Ukleja & Michelle M. Romano. (2007) Complications of Parenteral Nutrition. Gastroenterology Clinics of North America 36:1, pages 23-46.
Crossref
D. Lozano, l. Fern?ndez de castro, P. Esbrit & M.V. ?lvarez-arroyo. (2007) Diabetes mellitus y p?rdida de masa ?sea. Revista Espa?ola de Enfermedades Metab?licas ?seas 16:2, pages 29-33.
Crossref
K. WALLIS, J. R. F. WALTERS & A. FORBES. (2007) Review article: glucagon‐like peptide 2 – current applications and future directions. Alimentary Pharmacology & Therapeutics 25:4, pages 365-372.
Crossref
Vin Tangpricha, Menghua Luo, Concepción Fernández‐Estívariz, Li H. Gu, Niloofar Bazargan, Jan‐Michael Klapproth, Shanthi V. Sitaraman, John R. Galloway, Lorraine M. Leader & Thomas R. Ziegler. (2006) Growth Hormone Favorably Affects Bone Turnover and Bone Mineral Density in Patients With Short Bowel Syndrome Undergoing Intestinal Rehabilitation. Journal of Parenteral and Enteral Nutrition 30:6, pages 480-486.
Crossref
Jennifer L. EstallDaniel J. Drucker. (2006) Glucagon-Like Peptide-2. Annual Review of Nutrition 26:1, pages 391-411.
Crossref
Prue M Pereira & Julie E Bines. (2006) New growth factor therapies aimed at improving intestinal adaptation in short bowel syndrome. Journal of Gastroenterology and Hepatology 21:6, pages 932-940.
Crossref
Murat Cakir, Ilke Mungan, Caner Karahan, Gamze Can & Aysenur Okten. (2006) Necrotizing enterocolitis increases the bone resorption in premature infants. Early Human Development 82:6, pages 405-409.
Crossref
Olivier Goulet & Frédérique Sauvat. (2006) Short bowel syndrome and intestinal transplantation in children. Current Opinion in Clinical Nutrition and Metabolic Care 9:3, pages 304-313.
Crossref
Ian R Reid, Jillian Cornish & Paul A Baldock. (2006) Nutrition-Related Peptides and Bone Homeostasis. Journal of Bone and Mineral Research 21:4, pages 495-500.
Crossref
I.R. Reid. (2006) Obesity and osteoporosis. Annales d'Endocrinologie 67:2, pages 125-129.
Crossref
Olivier Goulet & Frank Ruemmele. (2006) Causes and Management of Intestinal Failure in Children. Gastroenterology 130:2, pages S16-S28.
Crossref
Palle Bekker Jeppesen. (2006) Glucagon-Like Peptide-2: Update of the Recent Clinical Trials. Gastroenterology 130:2, pages S127-S131.
Crossref
Juris J. Meier, Michael A. Nauck, Andrea Pott, Kai Heinze, Oliver Goetze, Kerem Bulut, Wolfgang E. Schmidt, Baptist Gallwitz & Jens J. Holst. (2006) Glucagon-Like Peptide 2 Stimulates Glucagon Secretion, Enhances Lipid Absorption, and Inhibits Gastric Acid Secretion in Humans. Gastroenterology 130:1, pages 44-54.
Crossref
Daniel J. Drucker. 2006. Physiology of the Gastrointestinal Tract. Physiology of the Gastrointestinal Tract 161 181 .
Dennis B Henriksen. (2005) The gut feeling of bone remodeling. BoneKEy-Osteovision 2:11, pages 16-23.
Crossref
Daniel J Drucker. (2005) Biologic actions and therapeutic potential of the proglucagon-derived peptides. Nature Clinical Practice Endocrinology & Metabolism 1:1, pages 22-31.
Crossref
Elaine M Sinclair & Daniel J. Drucker. (2005) Proglucagon-Derived Peptides: Mechanisms of Action and Therapeutic Potential. Physiology 20:5, pages 357-365.
Crossref
Jackie A Clowes, Sundeep Khosla & Richard Eastell. (2005) Potential Role of Pancreatic and Enteric Hormones in Regulating Bone Turnover. Journal of Bone and Mineral Research 20:9, pages 1497-1506.
Crossref
B. Vega Piñero, D. Peñalver Talavera & C. Fernández Estívariz. (2005) Nutrición basada en la evidencia en las fístulas digestivas el intestino corto. Endocrinología y Nutrición 52, pages 83-90.
Crossref
Eric D Shin, Daniel J Drucker & Patricia L Brubaker. (2005) Glucagon-like peptide 2: an update. Current Opinion in Endocrinology & Diabetes 12:1, pages 63-71.
Crossref
Charlene Compher & David Metz. 2004. Intestinal Failure and Rehabilitation. Intestinal Failure and Rehabilitation 115 127 .
Marwan S. Ghabril, Jamie Aranda-Michel & James S. Scolapio. (2004) Metabolic and catheter complications of parenteral nutrition. Current Gastroenterology Reports 6:4, pages 327-334.
Crossref
Olivier Goulet & Dominique Jan. (2004) Intestinal failure. Current Opinion in Organ Transplantation 9:2, pages 192-200.
Crossref
Olivier Goulet, Frank Ruemmele, Florence Lacaille & Virginie Colomb. (2004) Irreversible Intestinal Failure. Journal of Pediatric Gastroenterology and Nutrition 38:3, pages 250-269.
Crossref
James S. Scolapio. (2004) Current update of short-bowel syndrome. Current Opinion in Gastroenterology 20:2, pages 143-145.
Crossref
Olivier Goulet, Frank Ruemmele, Florence Lacaille & Virginie Colomb. (2004) Irreversible Intestinal Failure. Journal of Pediatric Gastroenterology and Nutrition 38:3, pages 250-269.
Crossref
Dennis B Henriksen, Peter Alexandersen, Nina H Bjarnason, Tina Vilsbøll, Bolette Hartmann, Eva EG Henriksen, Inger Byrjalsen, Thure Krarup, Jens J Holst & Claus Christiansen. (2003) Role of Gastrointestinal Hormones in Postprandial Reduction of Bone Resorption. Journal of Bone and Mineral Research 18:12, pages 2180-2189.
Crossref
Jennifer L. Estall & Daniel J. Drucker. (2003) Dual Regulation of Cell Proliferation and Survival via Activation of Glucagon-Like Peptide-2 Receptor Signaling. The Journal of Nutrition 133:11, pages 3708-3711.
Crossref
Jackie A. Clowes, Heather C. Allen, Donna M. Prentis, Richard Eastell & Aubrey Blumsohn. (2003) Octreotide Abolishes the Acute Decrease in Bone Turnover in Response to Oral Glucose. The Journal of Clinical Endocrinology & Metabolism 88:10, pages 4867-4873.
Crossref
Julian RF Walters. (2003) The role of the intestine in bone homeostasis. European Journal of Gastroenterology & Hepatology 15:8, pages 845-849.
Crossref
Julian R.F. Walters. (2003) Molecular and cellular biology of small intestinal differentiation, gene expression and hormonal responses. Current Opinion in Gastroenterology 19:2, pages 106-112.
Crossref
D.G. Burrin, B. Stoll & X. Guan. (2003) Glucagon-like peptide 2 function in domestic animals. Domestic Animal Endocrinology 24:2, pages 103-122.
Crossref
I.R Reid. (2002) Relationships among body mass, its components, and bone11Published simultaneously at BoneKEy-Osteovision (http://www.bonekey-ibms.org), a Web site sponsored by the International Bone and Mineral Society.. Bone 31:5, pages 547-555.
Crossref
Ian R Reid. (2002) Relationships among body mass, its components, and bone. BoneKEy-Osteovision.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.