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Research Article

Human Intraperitoneal Microdialysis: Increased Lactate/Pyruvate Ratio Suggests Early Visceral Ischaemia

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Pages 1007-1011 | Published online: 08 Jul 2009

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Read on this site (11)

Mark Bremholm Ellebæk, Freek Daams, Kjell Jansson, Peter Matthiessen, Cyril Cosse, Claus Fristrup, Signe Bremholm Ellebæk, Jonas Emil Sabroe & Niels Qvist. (2018) Peritoneal microdialysis as a tool for detecting anastomotic leakage in patients after left-side colon and rectal resection. A systematic review. Scandinavian Journal of Gastroenterology 53:12, pages 1625-1632.
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Jonas E. Sabroe, Mark B. Ellebæk & Niels Qvist. (2016) Intraabdominal microdialysis – methodological challenges. Scandinavian Journal of Clinical and Laboratory Investigation 76:8, pages 671-677.
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Niclas Högberg, Per-Ola Carlsson, Lars Hillered, Staffan Meurling & Anders Stenbäck. (2012) Intestinal ischemia measured by intraluminal microdialysis. Scandinavian Journal of Clinical and Laboratory Investigation 72:1, pages 59-66.
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Rajeshwara K. P. Adluri, Arvind V. Singh, Julian Skoyles, Mya Baker & Ian M. Mitchell. (2011) Measurement of intraperitoneal metabolites during hypothermic cardiopulmonary bypass using microdialysis. Scandinavian Cardiovascular Journal 45:4, pages 229-235.
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Tal M. Hörer, Lars Norgren & Kjell Jansson. (2011) Intraperitoneal glycerol levels and lactate/pyruvate ratio: early markers of postoperative complications. Scandinavian Journal of Gastroenterology 46:7-8, pages 913-919.
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Tal Hörer, Lars Norgren & Kjell Jansson. (2010) Complications but not obesity or diabetes mellitus have impact on the intraperitoneal lactate/pyruvate ratio measured by microdialysis. Scandinavian Journal of Gastroenterology 45:1, pages 115-121.
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Peter-Martin Krarup, Lars B. Stolle, Yazan F. Rawashdeh, Ole Skott, Jens Christian Djurhuus & Jorgen Froekiaer. (2007) Regional changes in renal cortical glucose, lactate and urea during acute unilateral ureteral obstruction. Scandinavian Journal of Urology and Nephrology 41:1, pages 47-53.
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K. Jansson, M. Jansson, M. Andersson, A. Magnuson, U. Ungerstedt & L. Norgren. (2005) Normal values and differences between intraperitoneal and subcutaneous microdialysis in patients after non‐complicated gastrointestinal surgery. Scandinavian Journal of Clinical and Laboratory Investigation 65:4, pages 273-282.
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Thorbjørn Sommer. (2005) Microdialysis of the bowel: the possibility of monitoring intestinal ischemia. Expert Review of Medical Devices 2:3, pages 277-286.
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K. Jansson, I. Strand, B. Redler, A. Magnuson, U. Ungerstedt & L. Norgren. (2004) Results of intraperitoneal microdialysis depend on the location of the catheter. Scandinavian Journal of Clinical and Laboratory Investigation 64:1, pages 63-70.
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K. Jansson, B. Redler, L. Truedsson, A. Magnuson, U. Ungerstedt & L. Norgren. (2004) Postoperative on‐line monitoring with intraperitoneal microdialysis is a sensitive clinical method for measuring increased anaerobic metabolism that correlates to the cytokine response. Scandinavian Journal of Gastroenterology 39:5, pages 434-439.
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Articles from other publishers (54)

Jurij Janež, Gašper Horvat, Aleš Jerin & Jan Grosek. (2022) The Significance of Blood and Peritoneal Fluid Biochemical Markers in Identifying Early Anastomotic Leak following Colorectal Resection—Findings from a Single-Center Study. Medicina 58:9, pages 1253.
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Ioannis Oikonomakis, Daniel T Jansson, Per Skoog, Kristofer F Nilsson, Adrian D Meehan, Tal M Hörer & Kjell Jansson. (2022) Fully covered self‐expandable metal stent placed over a stapled colon anastomosis in an animal model: A pilot study of colon metabolism over the stent. JGH Open 6:5, pages 338-343.
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Espen Lindholm, Nil Ekiz & Tor Inge Tønnessen. (2021) Monitoring of patients with microdialysis following pancreaticoduodenectomy—the MINIMUM study: study protocol for a randomized controlled trial. Trials 22:1.
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Pedja Cuk, Andreas Kristian Pedersen, Kate Lykke Lambertsen, Christian Backer Mogensen, Michael Festersen Nielsen, Per Helligsø, Ismail Gögenur & Mark Bremholm Ellebæk. (2021) Systemic inflammatory response in robot-assisted and laparoscopic surgery for colon cancer (SIRIRALS): study protocol of a randomized controlled trial. BMC Surgery 21:1.
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Mark Gray, Jamie R. K. Marland, Alan F. Murray, David J. Argyle & Mark A. Potter. (2021) Predictive and Diagnostic Biomarkers of Anastomotic Leakage: A Precision Medicine Approach for Colorectal Cancer Patients. Journal of Personalized Medicine 11:6, pages 471.
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M. B. Ellebæk, H. B. Rahr, S. Boye, C. Fristrup & N. Qvist. (2019) Detection of early anastomotic leakage by intraperitoneal microdialysis after low anterior resection for rectal cancer: a prospective cohort study. Colorectal Disease 21:12, pages 1387-1396.
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DT Jansson, I Oikonomakis, IEU Hall Strand, AD Meehan & KS Jansson. (2019) Metabolism, infl ammation and postoperative time are the key to early diagnosis of anastomotic leak. Journal of Surgery and Surgical Research 5:2, pages 078-085.
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Jenny Seilitz, Tal M. Hörer, Per Skoog, Mitra Sadeghi, Kjell Jansson, Birger Axelsson & Kristofer F. Nilsson. (2018) Splanchnic Circulation and Intraabdominal Metabolism in Two Porcine Models of Low Cardiac Output. Journal of Cardiovascular Translational Research 12:3, pages 240-249.
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Jonas Emil Sabroe, Niels Qvist & Mark Bremholm Ellebæk. (2018) Microdialysis in Postoperative Monitoring of Gastrointestinal Organ Viability: A Systematic Review. World Journal of Surgery 43:3, pages 944-954.
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Norbert Cibicek, Jiri Ehrmann, Jitka Proskova & Rostislav Vecera. (2018) Critical evaluation of colon submucosal microdialysis in awake, mobile rats. PLOS ONE 13:1, pages e0191041.
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Jonas E. Sabroe, Anne R. Axelsen, Mark B. Ellebæk, Bjarne Dahler-Eriksen & Niels Qvist. (2017) Intraperitoneal lactate/pyruvate ratio and the level of glucose and glycerol concentration differ between patients surgically treated for upper and lower perforations of the gastrointestinal tract: a pilot study. BMC Research Notes 10:1.
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Cloë L Sparreboom, Zhou-Qiao Wu, Jia-Fu Ji & Johan F Lange. (2016) Integrated approach to colorectal anastomotic leakage: Communication, infection and healing disturbances. World Journal of Gastroenterology 22:32, pages 7226.
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Kirsten Risby, Mark B. Ellebæk, Marianne S. Jakobsen, Steffen Husby & Niels Qvist. (2015) Intraperitoneal microdialysis in the postoperative surveillance of infants undergoing surgery for congenital abdominal wall defect: A pilot study. Journal of Pediatric Surgery 50:10, pages 1676-1680.
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Per Skoog, Tal Hörer, Kristofer F. Nilsson, Göran Ågren, Lars Norgren & Kjell Jansson. (2015) Intra-abdominal Hypertension—An Experimental Study of Early Effects on Intra-abdominal Metabolism. Annals of Vascular Surgery 29:1, pages 128-137.
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De-Hui Yi, Hao Liu, Ying Chen, Hong Li, Tie Xu & Yong-Feng Liu. (2014) Ischemic injury of the liver in a porcine model of cardiac death assessed by in vivo microdialysis. Molecular Biology Reports 41:10, pages 6611-6618.
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Mette A. Sørensen, Lars J. Petersen, Louise Bundgaard, Nils Toft & Stine Jacobsen. (2014) Regional disturbances in blood flow and metabolism in equine limb wound healing with formation of exuberant granulation tissue. Wound Repair and Regeneration 22:5, pages 647-653.
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Mark Ellebæk, Niels Qvist, Claus Fristrup & Michael B. Mortensen. (2014) Mediastinal microdialysis in the diagnosis of early anastomotic leakage after resection for cancer of the esophagus and gastroesophageal junction. The American Journal of Surgery 208:3, pages 397-405.
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Tal M. Hörer, Per Skoog, Kristofer F. Nilsson, Ioannis Oikonomakis, Thomas Larzon, Lars Norgren & Kjell Jansson. (2014) Intraperitoneal Metabolic Consequences of Supraceliac Aortic Balloon Occlusion in an Experimental Animal Study Using Microdialysis. Annals of Vascular Surgery 28:5, pages 1286-1295.
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J P Galea, P J Tyrrell, H P Patel, A Vail, A T King & S J Hopkins. (2014) Pitfalls in microdialysis methodology: an in vitro analysis of temperature, pressure and catheter use . Physiological Measurement 35:3, pages N21-N28.
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M. Emerich, M. Braeunig, H.W. Clement, R. Lüdtke & R. Huber. (2014) Mode of action of cupping—Local metabolism and pain thresholds in neck pain patients and healthy subjects. Complementary Therapies in Medicine 22:1, pages 148-158.
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F. Daams, Z. Wu, H. Cakir, T. M. Karsten & J. F. Lange. (2013) Identification of anastomotic leakage after colorectal surgery using microdialysis of the peritoneal cavity. Techniques in Coloproctology 18:1, pages 65-71.
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Lauri Pynnönen, Minna Minkkinen, Anders Perner, Sari Räty, Isto Nordback, Juhani Sand & Jyrki Tenhunen. (2013) Validation of Intraluminal and Intraperitoneal microdialysis in ischemic small intestine. BMC Gastroenterology 13:1.
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T.M. Hörer, P. Skoog, L. Norgren, A. Magnuson, L. Berggren, K. Jansson & T. Larzon. (2013) Intra-peritoneal Microdialysis and Intra-abdominal Pressure after Endovascular Repair of Ruptured Aortic Aneurysms. European Journal of Vascular and Endovascular Surgery 45:6, pages 596-606.
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Andreas Larentzakis, Konstantinos G. Toutouzas, Apostolos Papalois, Georgios Lapidakis, Stylianos Doulgerakis, Georgia Doulami, Panagiotis Drimousis, Dimitrios Theodorou & Stylianos Katsaragakis. (2013) Porcine model of hemorrhagic shock with microdialysis monitoring. Journal of Surgical Research 179:1, pages e177-e182.
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Robert Sauermann & Markus Zeitlinger. 2013. Microdialysis in Drug Development. Microdialysis in Drug Development 303 333 .
Niclas Högberg, Per-Ola Carlsson, Lars Hillered, Anders Stenbäck & Helene Engstrand Lilja. (2012) Intraluminal intestinal microdialysis detects markers of hypoxia and cell damage in experimental necrotizing enterocolitis. Journal of Pediatric Surgery 47:9, pages 1646-1651.
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C Ansorge, S Regner, R Segersvärd & L Strömmer. (2012) Early intraperitoneal metabolic changes and protease activation as indicators of pancreatic fistula after pancreaticoduodenectomy. British Journal of Surgery 99:1, pages 104-111.
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Norbert Cibicek, Helena Zivna, Eva Vrublova, Jaroslav Cibicek, Eva Cermakova & Vladimir Palicka. (2010) Gastric submucosal microdialysis in the detection of rat stomach ischemia—a comparison of the 3 H 2 O efflux technique with metabolic monitoring . Physiological Measurement 31:10, pages 1355-1368.
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Thomas Jonsson, Thomas Larzon, Kjell Jansson, Berndt Arfvidsson & Lars Norgren. (2008) Limb Ischemia After EVAR: An Effect of the Obstructing Introducer? . Journal of Endovascular Therapy 15:6, pages 695-701.
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Dimitrios Theodorou, Panagiotis G. Drimousis, Andreas Larentzakis, Apostolos Papalois, Konstantinos G. Toutouzas & Stylianos Katsaragakis. (2008) The Effects of Vasopressors on Perfusion of Gastric Graft after Esophagectomy. An Experimental Study. Journal of Gastrointestinal Surgery 12:9, pages 1497-1501.
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