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Original Article

Role of nuclear factor-κB, reactive oxygen species and cellular signaling in the early phase of acute pancreatitis

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Pages 103-108 | Received 10 May 2004, Accepted 20 Jul 2004, Published online: 08 Jul 2009

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Sezgin Zeren, Zulfu Bayhan, Cengiz Koçak, Fatma Emel Koçak, Mehmet Huseyin Metineren, Bircan Savran, Havva Kocak, Mustafa Cem Algin, Cuneyt Kahraman, Ahmet Kocak & Suleyman Cosgun. (2017) Antioxidant Effect of Ukrain Versus N-Acetylcysteine Against Acute Biliary Pancreatitis in An Experimental Rat Model. Journal of Investigative Surgery 30:2, pages 116-124.
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Hongxiang Liu, Yuan Li, Ling Wang, Hongying Chen, Jianting Guan & Zongguang Zhou. (2009) Aggravation of acute pancreatitis by heparan sulfate in mice. Scandinavian Journal of Gastroenterology 44:5, pages 626-632.
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Roland Andersson. (2006) Severe acute pancreatitis: The continued challenge. Journal of Organ Dysfunction 2:3, pages 131-132.
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Dalia Abdelhafez, Elshimaa Aboelkomsan, Abir El Sadik, Noha Lasheen, Sara Ashur, Amal Elshimy & George N. B. Morcos. (2021) The Role of Mesenchymal Stem Cells with Ascorbic Acid and N-Acetylcysteine on TNF-α, IL 1β, and NF-κβ Expressions in Acute Pancreatitis in Albino Rats. Journal of Diabetes Research 2021, pages 1-12.
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Chandraiah Godugu, Lakshmi P. Pasari, Amit Khurana, Pratibha Anchi, Mohd A. Saifi, Sapana P. Bansod & Shivaraju Annaldas. (2019) Crocin, an active constituent of Crocus sativus ameliorates cerulein induced pancreatic inflammation and oxidative stress . Phytotherapy Research 34:4, pages 825-835.
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Eman T. Mohammed, Khalid S. Hashem, Amr E. Ahmed, Mohamed Tarek Aly, Lotfi Aleya & Mohamed M. Abdel-Daim. (2020) Ginger extract ameliorates bisphenol A (BPA)-induced disruption in thyroid hormones synthesis and metabolism: Involvement of Nrf-2/HO-1 pathway. Science of The Total Environment 703, pages 134664.
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Shijin Xia, Jian Wang, Bill Kalionis, Wei Zhang & Yun Zhao. (2019) Genistein protects against acute pancreatitis via activation of an apoptotic pathway mediated through endoplasmic reticulum stress in rats. Biochemical and Biophysical Research Communications 509:2, pages 421-428.
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Laura Gaman, Dorin Dragos, Adelina Vlad, Georgiana Catalina Robu, Mugurel Petrinel Radoi, Laura Stroica, Mihaela Badea & Marilena Gilca. (2018) Phytoceuticals in Acute Pancreatitis: Targeting the Balance between Apoptosis and Necrosis. Evidence-Based Complementary and Alternative Medicine 2018, pages 1-27.
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Elroy Saldanha, Ramakrishna J. Pai, Thomas George, Sueallen D’Souza, Mohammed Adnan, Michael Pais, Taresh Naik, Reshmina C.C. D’Souza, Rithesh D’Cunha & Manjeshwar Shrinath Baliga. 2018. Therapeutic, Probiotic, and Unconventional Foods. Therapeutic, Probiotic, and Unconventional Foods 303 314 .
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Bing Han, Haoxin Zhou, Guang Jia, Yongwei Wang, Zengfu Song, Gang Wang, Shangha Pan, Xuewei Bai, Jiachen Lv & Bei Sun. (2016) MAPKs and Hsc70 are critical to the protective effect of molecular hydrogen during the early phase of acute pancreatitis. FEBS Journal 283:4, pages 738-756.
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Hang Zhao, Zhiying He, Dandan Huang, Jun Gao, Yanfang Gong, Hongyu Wu, Aifang Xu, Xiangjun Meng & Zhaoshen Li. (2016) Infusion of Bone Marrow Mesenchymal Stem Cells Attenuates Experimental Severe Acute Pancreatitis in Rats. Stem Cells International 2016, pages 1-10.
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LEI QIU, GUOJIAN YIN, LI CHENG, YUTING FAN, WENQIN XIAO, GE YU, MIAO XING, RONGRONG JIA, RUIQING SUN, XIUYING MA, GUOYONG HU, XINGPENG WANG, MAOCHUN TANG & YAN ZHAO. (2015) Astragaloside IV ameliorates acute pancreatitis in rats by inhibiting the activation of nuclear factor-κB. International Journal of Molecular Medicine 35:3, pages 625-636.
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Won Suk Kim, Won Kyo Jung & Sun Joo Park. (2015) Antioxidant Peptide Derived from Spirulina maxima Suppresses HIF1 α -Induced Invasive Migration of HT1080 Fibrosarcoma Cells . Journal of Chemistry 2015, pages 1-7.
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KAILIANG ZHAO, CHEN CHEN, QIAO SHI, WENHONG DENG, TENG ZUO, XIAOBO HE, TIANYI LIU, LIANG ZHAO & WEIXING WANG. (2014) Inhibition of glycogen synthase kinase-3β attenuates acute kidney injury in sodium taurocholate-induced severe acute pancreatitis in rats. Molecular Medicine Reports 10:6, pages 3185-3192.
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Jong-Min Park. (2014) Antioxidative phytoceuticals to ameliorate pancreatitis in animal models: An answer from nature. World Journal of Gastroenterology 20:44, pages 16570.
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Elroy Saldanha, Nadhini Joseph, Rithin Ravi, Ashish Kumar, Vaishaka Shetty, Raja Fayad & Manjeshwar Shrinath Baliga. 2014. Polyphenols in Human Health and Disease. Polyphenols in Human Health and Disease 427 433 .
Xuewei Bai, Zengfu Song, Yanmei Zhou, Shangha Pan, Feng Wang, Zuoming Guo, Maitao Jiang, Gang Wang, Rui Kong & Bei Sun. (2013) The apoptosis of peripheral blood lymphocytes promoted by hyperbaric oxygen treatment contributes to attenuate the severity of early stage acute pancreatitis in rats. Apoptosis 19:1, pages 58-75.
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Bing-Qing Du, Yue-Ming Yang, Yong-Hua Chen, Xu-Bao Liu & Gang Mai. (2013) N-Acetylcysteine Improves Pancreatic Microcirculation and Alleviates the Severity of Acute Necrotizing Pancreatitis. Gut and Liver 7:3, pages 357-362.
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Dong-Won Ahn, Ji Kon Ryu, Jaihwan Kim, Yong-Tae Kim, Yong Bum Yoon, Kyoungbun Lee & Jin Tae Hong. (2013) Inflexinol Reduces Severity of Acute Pancreatitis by Inhibiting Nuclear Factor-κB Activation in Cerulein-Induced Pancreatitis. Pancreas 42:2, pages 279-284.
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Shuli Yang, Men Bing, Fengmei Chen, Ying Sun, Huang Chen & Weichang Chen. (2012) Autophagy Regulation by the Nuclear Factor κB Signal Axis in Acute Pancreatitis. Pancreas 41:3, pages 367-373.
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Mei H. Wan, Wei Huang, Diane Latawiec, Kun Jiang, David M. Booth, Victoria Elliott, Rajarshi Mukherjee & Qing Xia. (2012) Review of experimental animal models of biliary acute pancreatitis and recent advances in basic research. HPB 14:2, pages 73-81.
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Ufuk Kutluana, Nevin Oruc, Deniz Nart, Bunyamin Kaptanoglu, Nadir Yonetci & Omer Ozutemiz. (2010) Leflunomide. Pancreas 39:2, pages 237-242.
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Kwang Ro Joo, Hyun Phil Shin, Jae Myung Cha, Sua Nam & Youngbuhm Huh. (2009) Effect of Korean Red Ginseng on Superoxide Dismutase Inhibitor-Induced Pancreatitis in Rats. Pancreas 38:6, pages 661-666.
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Dirk Uhlmann, Heike Lauer, Frederik Serr & Helmut Witzigmann. (2008) Pathophysiological role of platelets and platelet system in acute pancreatitis. Microvascular Research 76:2, pages 114-123.
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Xi Chen, Shun-Le Li, Tao Wu & Ji-Dong Liu. (2008) Proteasome inhibitor ameliorates severe acute pancreatitis and associated lung injury of rats. World Journal of Gastroenterology 14:20, pages 3249.
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Stephen J. D. O’Keefe. 2008. Nutrition and Gastrointestinal Disease. Nutrition and Gastrointestinal Disease 107 122 .
Chun-Li Su, Chun-Chun Cheng, Mao-Tsun Lin, Hsiao-Chun Yeh, Meng-Chou Lee, Jenq-Chang Lee & Shen-Jeu Won. (2007) Staphylococcal enterotoxin C1-induced pyrogenic cytokine production in human peripheral blood mononuclear cells is mediated by NADPH oxidase and nuclear factor-kappa B. The FEBS Journal 274:14, pages 3633-3645.
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Stephen J.D. O'Keefe & Sumit Sharma. (2007) Nutrition Support in Severe Acute Pancreatitis. Gastroenterology Clinics of North America 36:2, pages 297-312.
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Irfan A. Rizvi, Kristine Robinson, David W. McFadden, Dale R. Riggs, Barbara J. Jackson & Linda Vona-Davis. (2006) Peptide YY Reverses TNF-α Induced Transcription Factor Binding of Interferon Regulatory Factor-1 and p53 in Pancreatic Acinar Cells. Journal of Surgical Research 136:1, pages 25-30.
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Ling Cheng, Weibiao Cao, Claudio Fiocchi, Jose Behar, Piero Biancani & Karen M. Harnett. (2006) HCl-induced inflammatory mediators in cat esophageal mucosa and inflammatory mediators in esophageal circular muscle in an in vitro model of esophagitis. American Journal of Physiology-Gastrointestinal and Liver Physiology 290:6, pages G1307-G1317.
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Kristine Robinson, Linda Vona-Davis, Dale Riggs, Barbara Jackson & David McFadden. (2006) Peptide YY Attenuates STAT1 and STAT3 Activation Induced by TNF-α in Acinar Cell Line AR42J. Journal of the American College of Surgeons 202:5, pages 788-796.
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Tiziana Genovese, Emanuela Mazzon, Rosanna Di Paola, Carmelo Muià, Concetta Crisafulli, Marta Menegazzi, Giuseppe Malleo, Hisanori Suzuki & Salvatore Cuzzocrea. (2006) HYPERICUM PERFORATUM ATTENUATES THE DEVELOPMENT OF CERULEIN-INDUCED ACUTE PANCREATITIS IN MICE. Shock 25:2, pages 161-167.
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Tamás Letoha, Csaba Somlai, Tamás Takács, Annamária Szabolcs, Zoltán RakonczayJr.Jr., Katalin Jármay, Tamás Szalontai, Ilona Varga, József Kaszaki, Imre Boros, Ernő Duda, László Hackler, István Kurucz & Botond Penke. (2005) The proteasome inhibitor MG132 protects against acute pancreatitis. Free Radical Biology and Medicine 39:9, pages 1142-1151.
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J. Y. Kim & J. Y. Ro. (2005) Signal Pathway of Cytokines Produced by Reactive Oxygen Species Generated from Phorbol Myristate Acetate-Stimulated HMC-1 Cells. Scandinavian Journal of Immunology 62:1, pages 25-35.
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