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ORIGINAL ARTICLE

Polaprezinc (N-(3-aminopropionyl)-L-histidinato zinc) ameliorates dextran sulfate sodium-induced colitis in mice

, PhD, , , , , & show all
Pages 1321-1327 | Received 01 Feb 2005, Published online: 08 Jul 2009

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Articles from other publishers (34)

Changlin Wen, Jiayu Wang, Zhenhua Sun, Rao Zhong, Mengjie Li, Xuemei Shen, Qiaobo Ye, Kaihua Qin & Xi Peng. (2023) Dietary Zinc Ameliorates TNBS-Induced Colitis in Mice Associated with Regulation of Th1/Th2/Th17 Balance and NF-κB/NLRP3 Signaling Pathway. Biological Trace Element Research.
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Fansen Meng, Siying Zhu, Meiliang Gong, Hongjin Tao, Weihua Wang & Gangshi Wang. (2023) Heat shock protein 70 is involved in polaprezinc driven cell protection against Helicobacter pylori-induced injury. International Journal of Medical Microbiology 313:3, pages 151582.
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Makoto Kondo, Yoshiaki Matsushima, Takehisa Nakanishi, Shohei Iida, Koji Habe & Keiichi Yamanaka. (2023) Seborrheic Keratosis Caused by Human Papillomavirus Type 20 Ameliorated by Zinc Oxide Ointment. Clinics and Practice 13:2, pages 367-371.
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Konstantinos Efthymakis & Matteo Neri. (2022) The role of Zinc L-Carnosine in the prevention and treatment of gastrointestinal mucosal disease in humans: a review.. Clinics and Research in Hepatology and Gastroenterology 46:7, pages 101954.
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Daisuke Yamaguchi, Kazuo Takeuchi, Atsuko Ueno, Daisuke Kato, Shin Miyamae & Hiroshi Murakami. (2021) Experimental Repositioning of Geranylgeranylacetone to Enhance Bone Remodeling. Journal of Hard Tissue Biology 30:1, pages 1-6.
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Yu Wang, Hongjing Zhao, Xiaopan Nie, Menghao Guo, Guangshun Jiang & Mingwei Xing. (2020) Zinc application alleviates the adverse renal effects of arsenic stress in a protein quality control way in common carp. Environmental Research 191, pages 110063.
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Inga Wessels & Lothar Rink. (2020) Micronutrients in autoimmune diseases: possible therapeutic benefits of zinc and vitamin D. The Journal of Nutritional Biochemistry 77, pages 108240.
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Reyhaneh Moradi‐Marjaneh, Maryam Paseban & Mahdi Moradi Marjaneh. (2019) Hsp70 inhibitors: Implications for the treatment of colorectal cancer. IUBMB Life 71:12, pages 1834-1845.
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Abdullah Hoter & Hassan Y. Naim. (2019) The Functions and Therapeutic Potential of Heat Shock Proteins in Inflammatory Bowel Disease—An Update. International Journal of Molecular Sciences 20:21, pages 5331.
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Ozden Yildirim Akan, Pinar Ortan & Ferda Hosgorler. 2019. Heat Shock Proteins in Neuroscience. Heat Shock Proteins in Neuroscience 273 303 .
Farid Poursadegh, Mitra Ahadi, Hassan Vosoughinia, Maryam Salehi, Ali Beheshti Namdar, Mohammad Reza Farzanehfar, Bahram Memar & Reza Ziaolhagh. (2018) A STROBE compliant observational study on trace elements in patients with ulcerative colitis and their relationship with disease activity. Medicine 97:52, pages e13523.
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Keigo Nishida & Ryota Uchida. (2018) Role of Zinc Signaling in the Regulation of Mast Cell-, Basophil-, and T Cell-Mediated Allergic Responses. Journal of Immunology Research 2018, pages 1-9.
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Miyuki Ogata, Tran Van Hung, Hiroyuki Tari, Teruaki Arakawa & Takuya Suzuki. (2017) Dietary psyllium fiber increases intestinal heat shock protein 25 expression in mice. Nutrition Research 39, pages 25-33.
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Marie-Edith Arnal & Jean-Paul Lallès. (2016) Gut epithelial inducible heat-shock proteins and their modulation by diet and the microbiota. Nutrition Reviews 74:3, pages 181-197.
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Claudia Schubert, Karina Guttek, Annegret Reinhold, Kurt Grüngreiff & Dirk Reinhold. (2015) The influence of the trace element zinc on the immune system. LaboratoriumsMedizin 39:s1.
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Claudia Schubert, Karina Guttek, Annegret Reinhold, Kurt Grüngreiff & Dirk Reinhold. (2015) Der Einfluss des Spurenelements Zink auf das Immunsystem. LaboratoriumsMedizin 39:3, pages 135-144.
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Sakino Noda, Soichi Tanabe & Takuya Suzuki. (2013) Naringenin enhances intestinal barrier function through the expression and cytoskeletal association of tight junction proteins in Caco-2 cells. Molecular Nutrition & Food Research 57:11, pages 2019-2028.
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Keigo NISHIDA. (2013) New Knowledge from Past Decade: Role of Zinc in Immune Systemここまで分かった亜鉛の免疫システムにおける役割. Nippon Eiseigaku Zasshi (Japanese Journal of Hygiene) 68:3, pages 145-152.
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Toru Kono, Toshiyuki Asama, Naoyuki Chisato, Yoshiaki Ebisawa, Taishi Okayama, Kouji Imai, Hidenori Karasaki, Hiroyuki Furukawa & Masashi Yoneda. (2012) Polaprezinc prevents ongoing thioacetamide-induced liver fibrosis in rats. Life Sciences 90:3-4, pages 122-130.
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Toshiyuki Fukada, Satoru Yamasaki, Keigo Nishida, Masaaki Murakami & Toshio Hirano. (2011) Zinc homeostasis and signaling in health and diseases. JBIC Journal of Biological Inorganic Chemistry 16:7, pages 1123-1134.
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Hiroshi Doi, Norihiko Kamikonya, Yasuhiro Takada, Masayuki Fujiwara, Keita Tsuboi, Hiroyuki Inoue, Masao Tanooka, Takeshi Nakamura, Toshiyuki Shikata, Tohru Tsujimura & Shozo Hirota. (2011) Efficacy of Polaprezinc for Acute Radiation Proctitis in a Rat Model. International Journal of Radiation Oncology*Biology*Physics 80:3, pages 877-884.
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Marloes A.A. Schepens, Carolien Vink, Arjan J. Schonewille, Gerard Dijkstra, Roelof van der Meer & Ingeborg M.J. Bovee-Oudenhoven. (2011) Dietary heme adversely affects experimental colitis in rats, despite heat-shock protein induction. Nutrition 27:5, pages 590-597.
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Yajing Zhang, Shinichi Okamura, Tomohiro Kudo, Takashige Masuo & Masatomo Mori. (2011) Calcineurin inhibition by polaprezinc in rats with experimentally-induced colitis. Life Sciences 88:9-10, pages 432-439.
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Frederick Pfister, Eva Riedl, Qian Wang, Franziska vom Hagen, Martina Deinzer, Martin C. Harmsen, Grietje Molema, Benito Yard, Yuxi Feng & Hans-Peter Hammes. (2011) Oral Carnosine Supplementation Prevents Vascular Damage in Experimental Diabetic Retinopathy. Cellular Physiology and Biochemistry 28:1, pages 125-136.
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Tatsushi Omatsu, Yuji Naito, Osamu Handa, Katsura Mizushima, Natsuko Hayashi, Ying Qin, Akihito Harusato, Ikuhiro Hirata, Etsuko Kishimoto, Hitomi Okada, Kazuhiko Uchiyama, Takeshi Ishikawa, Tomohisa Takagi, Nobuaki Yagi, Satoshi Kokura, Hiroshi Ichikawa & Toshikazu Yoshikawa. (2010) Reactive oxygen species-quenching and anti-apoptotic effect of polaprezinc on indomethacin-induced small intestinal epithelial cell injury. Journal of Gastroenterology 45:7, pages 692-702.
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Chika Kitabayashi, Toshiyuki Fukada, Minoru Kanamoto, Wakana Ohashi, Shintaro Hojyo, Toru Atsumi, Naoko Ueda, Ichiro Azuma, Hiroshi Hirota, Masaaki Murakami & Toshio Hirano. (2010) Zinc suppresses Th17 development via inhibition of STAT3 activation. International Immunology 22:5, pages 375-386.
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Shuzo Ohata, Chihiro Moriyama, Atsushi Yamashita, Tadashi Nishida, Chiaki Kusumoto, Shinsuke Mochida, Yukari Minami, Junya Nakada, Kohei Shomori, Yoshimi Inagaki, Yoshiji Ohta & Tatsuya Matsura. (2010) Polaprezinc Protects Mice against Endotoxin Shock. Journal of Clinical Biochemistry and Nutrition 46:3, pages 234-243.
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Jun Ying Xiang, Li Guo Wu, Xiao Li Huang, Meng Zhang, Lan Pen, Qin Ouyan & Hua Tian Gan. (2009) Amelioration of murine dextran sulfate sodium-induced colitis by nuclear factor-κb decoy oligonucleotides. The American Journal of Surgery 197:6, pages 797-805.
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Tadashi Nishida, Shuzo Ohata, Chiaki Kusumoto, Shinsuke Mochida, Junya Nakada, Yoshimi Inagaki, Yoshiji Ohta & Tatsuya Matsura. (2009) Zinc Supplementation with Polaprezinc Protects Mouse Hepatocytes against Acetaminophen-Induced Toxicity via Induction of Heat Shock Protein 70. Journal of Clinical Biochemistry and Nutrition 46:1, pages 43-51.
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Anouk Waeytens, Martine De Vos & Debby Laukens. (2009) Evidence for a Potential Role of Metallothioneins in Inflammatory Bowel Diseases. Mediators of Inflammation 2009, pages 1-9.
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Dei Kui Zhang, Li Na Cheng, Xiao Li Huang, Wei Shi, Jun Ying Xiang & Hua Tian Gan. (2008) Tetrandrine ameliorates dextran-sulfate-sodium-induced colitis in mice through inhibition of nuclear factor -κB activation. International Journal of Colorectal Disease 24:1, pages 5-12.
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C. D. Tran, J. M. Ball, S. Sundar, P. Coyle & G. S. Howarth. (2007) The Role of Zinc and Metallothionein in the Dextran Sulfate Sodium-Induced Colitis Mouse Model. Digestive Diseases and Sciences 52:9, pages 2113-2121.
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Michiro Otaka, Masaru Odashima & Sumio Watanabe. (2006) Role of heat shock proteins (molecular chaperones) in intestinal mucosal protection. Biochemical and Biophysical Research Communications 348:1, pages 1-5.
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Tatsuya Ohkawara. (2006) Polaprezinc protects human colon cells from oxidative injury induced by hydrogen peroxide: Relevant to cytoprotective heat shock proteins. World Journal of Gastroenterology 12:38, pages 6178.
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