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Scandinavian Journal of Gastroenterology Volume 41, 2006 - Issue 12
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ORIGINAL ARTICLE

Effect of carvedilol on portal hypertension depends on the degree of endothelial activation and inflammatory changes

Radan Bruha 4th Medical Department, Charles University, Prague, Czech Republic; Internal Clinic, Central Military Hospital and Charles University, Prague, Czech RepublicCorrespondence[email protected]
, PhD , MD,
Libor Vitek Institute of Clinical Biochemistry and Laboratory Diagnostics, General Teaching Hospital, 1st Faculty of Medicine, Charles University, Prague, Czech Republic; Internal Clinic, Central Military Hospital and Charles University, Prague, Czech Republic
,
Jaromir Petrtyl 4th Medical Department, Charles University, Prague, Czech Republic; Internal Clinic, Central Military Hospital and Charles University, Prague, Czech Republic
,
Martin Lenicek Institute of Clinical Biochemistry and Laboratory Diagnostics, General Teaching Hospital, 1st Faculty of Medicine, Charles University, Prague, Czech Republic; Internal Clinic, Central Military Hospital and Charles University, Prague, Czech Republic
,
Petr Urbanek 4th Medical Department, Charles University, Prague, Czech Republic; Internal Clinic, Central Military Hospital and Charles University, Prague, Czech Republic
,
Jaroslav Zelenka Institute of Clinical Biochemistry and Laboratory Diagnostics, General Teaching Hospital, 1st Faculty of Medicine, Charles University, Prague, Czech Republic; Internal Clinic, Central Military Hospital and Charles University, Prague, Czech Republic
,
Marie Jachymova 4th Medical Department, Charles University, Prague, Czech Republic; Internal Clinic, Central Military Hospital and Charles University, Prague, Czech Republic
,
Tomislav Svestka 4th Medical Department, Charles University, Prague, Czech Republic; Internal Clinic, Central Military Hospital and Charles University, Prague, Czech Republic
,
Milan Kalab 4th Medical Department, Charles University, Prague, Czech Republic; Internal Clinic, Central Military Hospital and Charles University, Prague, Czech Republic
,
Miroslav Dousa 4th Medical Department, Charles University, Prague, Czech Republic; Internal Clinic, Central Military Hospital and Charles University, Prague, Czech Republic
&
Zdenek Marecek Institute of Clinical Biochemistry and Laboratory Diagnostics, General Teaching Hospital, 1st Faculty of Medicine, Charles University, Prague, Czech Republic; Internal Clinic, Central Military Hospital and Charles University, Prague, Czech Republic
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Pages 1454-1463 | Received 06 Mar 2006, Published online: 08 Jul 2009

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Lise Hobolth, Søren Møller, Henning Grønbæk, Klaus Roelsgaard, Flemming Bendtsen & Erik Feldager Hansen. (2012) Carvedilol or propranolol in portal hypertension? A randomized comparison. Scandinavian Journal of Gastroenterology 47:4, pages 467-474.
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Articles from other publishers (11)

Alexandr S. Ivanov, Irina V. Garmasch, Olga S. Arisheva, Mariya A. Markova, Anna S. Melnik, Natalya N. Terebilina, Valeria Yu. Baronets, Daniil I. Peregud, Ekaterina V. Tarasenko & Zhanna D. Kobalava. (2018) Association of SNPs in the Promoter Regions of VEGF (rs699947 и rs2010963), ICAM1 (rs281437) and ET-1 (rs1800541) with Serum Levels of Related Proteins and Alcoholic Liver Cirrhosis Risk. Annals of the Russian academy of medical sciences 73:6, pages 368-377.
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Antony P Zacharias, Rebecca Jeyaraj, Lise Hobolth, Flemming Bendtsen, Lise Lotte Gluud & Marsha Y Morgan. (2018) Carvedilol versus traditional, non-selective beta-blockers for adults with cirrhosis and gastroesophageal varices. Cochrane Database of Systematic Reviews 2018:10.
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Satish Maharaj, Karan Seegobin, Julio Perez-Downes, Belinda Bajric, Simone Chang & Pramod Reddy. (2017) Severe carvedilol toxicity without overdose – caution in cirrhosis. Clinical Hypertension 23:1.
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Tong Li, Wenbo Ke, Ping Sun, Xiang Chen, Ajay Belgaumkar, Yuanjian Huang, Wenjing Xian, Jinjin Li & Qichang Zheng. (2016) Carvedilol for portal hypertension in cirrhosis: systematic review with meta-analysis. BMJ Open 6:5, pages e010902.
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Dan Lin, Zhe Wang, Junwei Li, Li Wang, Shuanghu Wang, Guo-Xin Hu & Xinshe Liu. (2016) The Effect of Apatinib on the Metabolism of Carvedilol Both in vitro and in vivo. Pharmacology 97:1-2, pages 31-37.
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Urszula Wereszczynka-Siemiatkowska, Agnieszka Swidnicka-Siergiejko, Andrzej Siemiatkowski, Zofia Bondyra, Justyna Wasielica-Berger, Barbara Mroczko, Jacek Janica & Andrzej Dabrowski. (2015) Endothelin 1 and transforming growth factor-β1 correlate with liver function and portal pressure in cirrhotic patients. Cytokine 76:2, pages 144-151.
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Cecilia Miñano & Guadalupe Garcia-Tsao. (2010) Clinical Pharmacology of Portal Hypertension. Gastroenterology Clinics of North America 39:3, pages 681-695.
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Dhiraj Tripathi & Peter C. Hayes. (2010) The role of carvedilol in the management of portal hypertension. European Journal of Gastroenterology & Hepatology 22:8, pages 905-911.
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Jaime Bosch. (2010) Carvedilol for portal hypertension in patients with cirrhosis. Hepatology 51:6, pages 2214-2218.
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Emmanuel A. Tsochatzis, Christos K. Triantos & Andrew K. Burroughs. (2009) Carvedilol—the best β-blocker for primary prophylaxis?. Nature Reviews Gastroenterology & Hepatology 6:12, pages 692-694.
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Dhiraj Tripathi, James W. Ferguson, Narendra Kochar, Joanna A. Leithead, George Therapondos, Norma C. Mcavoy, Adrian J. Stanley, Ewan H. Forrest, William S. Hislop, Peter R. Mills & Peter C. Hayes. (2009) Randomized controlled trial of carvedilol versus variceal band ligation for the prevention of the first variceal bleed. Hepatology 50:3, pages 825-833.
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