2
Views
76
CrossRef citations to date
0
Altmetric
Articles

Role of a False Neurotransmitter, Octopamine, in the Pathogenesis of Hepatic and Renal Encephalopathy

, , &
Pages 465-472 | Received 12 Jan 1973, Accepted 20 Apr 1973, Published online: 16 Oct 2020

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (1)

H. Ring-Larsen, K. Tønnesen, M. Holm-Bentzen & L. A. Christiansen. (1979) Renal and Cerebral Blood Flow in Experimental Liver Failure in the Pig. Scandinavian Journal of Gastroenterology 14:1, pages 91-96.
Read now

Articles from other publishers (75)

Natalie Meert, Eva Schepers, Rita De Smet, Angel Argiles, Gerald Cohen, Reinhold Deppisch, Tilman Drüeke, Ziad Massy, Goce Spasovski, Bernd Stegmayr, Walter Zidek, Joachim Jankowski & Raymond Vanholder. (2007) Inconsistency of Reported Uremic Toxin Concentrations. Artificial Organs 31:8, pages 600-611.
Crossref
Takashi Bungo, Tamae Higaki, Hiroshi Ueda & Mitsuhiro Furuse. (2002) Comparison of the Effects of Octopamine and Noradrenaline on Feeding and Sleep-like Behaviour in Fasted Chicks.. The Journal of Poultry Science 39:4, pages 316-322.
Crossref
Erwin Kuntz & Hans-Dieter KuntzErwin Kuntz & Hans-Dieter Kuntz. 2002. Hepatology. Hepatology 233 254 .
V. Martina, M. Tagliabue, G. A. Bruno, G. Bonetti, V. Brancaleoni, I. Meineri, G. Saracco, E. Zumpano, C. Manieri & F. Camanni. (1998) The altered plasma amino acid pattern is responsible for the paradoxical growth hormone response to the oral glucose tolerance test in liver cirrhosis. Clinical Endocrinology 48:2, pages 175-180.
Crossref
Darrell D. Mousseau & Roger F. Butterworth. 1995. Current Neurochemical and Pharmacological Aspects of Biogenic Amines - Their Function, Oxidative Deamination and Inhibition. Current Neurochemical and Pharmacological Aspects of Biogenic Amines - Their Function, Oxidative Deamination and Inhibition 277 284 .
F. von Bruchhausen, S. Ebel, E. Hackenthal, G. Dannhardt, A. W. Frahm, U. Holzgrabe, K. Keller, E. Nürnberg, H. Rimpler, G. Schneider, P. Surmann, H. U. Wolf & G. Wurm. 1993. Hagers Handbuch der Pharmazeutischen Praxis. Hagers Handbuch der Pharmazeutischen Praxis 1221 1293 .
J. K. Brown & H. Imam. (1991) Interrelationships of liver and brain with special reference to reye syndrome. Journal of Inherited Metabolic Disease 14:4, pages 436-458.
Crossref
Takeo Yonekura, Shinkichi Kamata, Masafumi Wasa, Akira Okada, Sumio Kawata & Seiichiro Tarui. (1991) Simultaneous analysis of plasma phenethylamine, phenylethanolamine, tyramine and octopamine in patients with hepatic encephalopathy. Clinica Chimica Acta 199:1, pages 91-97.
Crossref
J. K. Brown & H. Imam. 1991. Journal of Inherited Metabolic Disease. Journal of Inherited Metabolic Disease 436 458 .
Ljusk Siw Eriksson & Harold O. Conn. (1989) Branched-chain amino acids in the management of hepatic encephalopathy: An analysis of variants. Hepatology 10:2, pages 228-246.
Crossref
Bruce A. Davis. (1989) Biogenic amines and their metabolites in body fluids of normal, psychiatric and neurological subjects. Journal of Chromatography A 466, pages 89-218.
Crossref
J. M. Saavedra. 1989. Catecholamines II. Catecholamines II 181 210 .
Carlo Cangiano, Patrizia Cardelli‐Cangiano, Antonia Cascino, Fabrizio Ceci, Anna Fiori, Massimo Mulieri, Maurizio Muscaritoli, Claudio Barberini, Roberto Strom & Filippo Rossi Fanelli. (2006) Uptake of Amino Acids by Brain Micro vessels Isolated from Rats with Experimental Chronic Renal Failure. Journal of Neurochemistry 51:6, pages 1675-1681.
Crossref
Darryl T. Hiyama & Josef E. Fischer. (1988) Invited Review: Nutritional Support in Hepatic Failure. Nutrition in Clinical Practice 3:3, pages 96-105.
Crossref
Takeo Yonekura, Shinkichi Kamata, Masafumi Wasa, Akira Okada, Atsushi Yamatodani, Takehiko Watanabe & Hiroshi Wada. (1988) Simultaneous determination of plasma phenethylamine, phenylethanolamine, tyramine and octopamine by high-performance liquid chromatography using derivatization with fluorescamine. Journal of Chromatography B: Biomedical Sciences and Applications 427, pages 320-325.
Crossref
J.F. Coulon, P. Lacroix, Ph. Linee & J.C. David. (1987) Effects of triethyltin on brain octopamines and their metabolism in the rat. European Journal of Pharmacology 135:1, pages 53-60.
Crossref
F. Rossi-Fanelli, A. Cascino, R. Strom, P. Cardelli-Cangiano, F. Ceci, M. Muscaritoli & C. Cangiano. (1987) Amino acids and hepatic encephalopathy. Progress in Neurobiology 28:3, pages 277-301.
Crossref
Jean-Claude David & Jean-François Coulon. (1985) Octopamine in invertebrates and vertebrates. A review. Progress in Neurobiology 24:2, pages 141-185.
Crossref
W. Gerok & D. Häussinger. 1984. Glutamine Metabolism in Mammalian Tissues. Glutamine Metabolism in Mammalian Tissues 257 277 .
Helmer Ring‐Larsen. (2008) Hepatic nephropathy, related to haemodynamics. Liver 3:5, pages 265-289.
Crossref
Ori S. Better & Robert W. Schrier. (1983) Disturbed volume homeostasis in patients with cirrhosis of the liver. Kidney International 23:2, pages 303-311.
Crossref
S. Carlone, P. Serra, M.O. Farber, L. Roberts & F. Manfredi. (1982) Red Blood Cell Alkalosis and Decreased Oxyhemoglobin Affinity. The American Journal of the Medical Sciences 284:2, pages 8-16.
Crossref
Henning Laursen. (1982) Cerebral vessels and glial cells in liver disease. Acta Neurologica Scandinavica 65:5, pages 381-412.
Crossref
Giulio Marchesini, Marco Zoli, Cristina Dondi, Angela Angiolini, Alberto Melli & Emilio Pisi. (1982) Ammonia-induced changes in pancreatic hormones and plasma amino acids in patients with liver cirrhosis. Digestive Diseases and Sciences 27:5, pages 406-412.
Crossref
CARLO CANGIANO, MARK O. FARBER, PATRIZIA CARDELLI‐CANGIANO, FILIPPO ROSSI‐FANELLI, ANTONIA CASCINO, LIVIO CAPOCACCIA, EDWARD M. COCKERILL & FELICE MANFREDI. (2008) Plasma levels of false neurotransmitters across the brain in portal‐systemic encephalopathy. European Journal of Clinical Investigation 12:1, pages 15-21.
Crossref
Bruce A. Davis, Peter H. Yu, Kenneth Carlson, Karl O'Sullivan & Alan A. Boulton. (1982) Plasma levels of phenylacetic acid, m- and p-hydroxyphenylacetic acid, and platelet monoamine oxidase activity in schizophrenic and other patients. Psychiatry Research 6:1, pages 97-105.
Crossref
J. E. Fischer. (1982) Amino acids in hepatic coma. Digestive Diseases and Sciences 27:2, pages 97-102.
Crossref
Glen B. Baker & Ronald T. Coutts. 1982. Evaluation of Analytical Methods in Biological Systems - Analysis of Biogenic Amines. Evaluation of Analytical Methods in Biological Systems - Analysis of Biogenic Amines 1 13 .
. (1982) FALSE NEUROTRANSMITTERS AND HEPATIC FAILURE. The Lancet 319:8263, pages 86-87.
Crossref
Alan A. Boulton & Augusto V. Juorio. 1982. Chemical and Cellular Architecture. Chemical and Cellular Architecture 189 222 .
Stephen R. Philips. 1982. Experimental Neurochemistry. Experimental Neurochemistry 103 132 .
H. Hörtnagl, H. Lochs, G. Kleinberger, J. M. Hackl, A. F. Hammerle, H. Binder & F. Wewalka. (1981) Plasma catecholamines in hepatic coma and liver cirrhosis: Role of octopaminePlasmakatecholamine im Coma hepaticum und bei Leberzirrhose: die Rolle von Octopamin. Klinische Wochenschrift 59:20, pages 1159-1164.
Crossref
A. Bozzi, P. Cardelli-Cangiano, R. Strom, O. Riggio, F. Rossi Fanelli, C. Cangiano, S. Gentile & L. Capocaccia. (1981) Simultaneous radioenzymatic determination of phenylethylamine, phenylethanolamine, tyramine and octopamine in plasma of patients with hepatic encephalopathy. Clinical Biochemistry 14:4, pages 187-190.
Crossref
Giulio Marchesini, Marco Zoli, Angela Angiolini, Cristina Dondi, Francesco B. Bianchi & Emilio Pisi. (1981) Muscle protein breakdown in liver cirrhosis and the role of altered carbohydrate metabolism. Hepatology 1:4, pages 294-299.
Crossref
Yuzo Sato, Siw Eriksson, Lars Hagenfeldt & John Wahren. (2008) Influence of branched‐chain amino acid infusion on arterial concentrations and brain exchange of amino acids in patients with hepatic cirrhosis. Clinical Physiology 1:2, pages 151-165.
Crossref
Michael D. Norenberg. 1981. 303 352 .
H. Lösgen, E. Neumann, G. Eisenbach, F. W. Schmidt & G. Brunner. 1981. Artificial Liver Support. Artificial Liver Support 153 158 .
Kiyoshi Kobayashi, Andras Foti, Vincent Dequattro, Rainer Kolloch & Lino Miano. (1980) A radioenzymatic assay for free and conjugated normetanephrine and octopamine excretion in man. Clinica Chimica Acta 107:3, pages 163-173.
Crossref
V. P. Choudhry & M. K. Bhan. (1980) Renal failure in hepatic failure. The Indian Journal of Pediatrics 47:6, pages 563-566.
Crossref
. (1980) BIOCHEMICAL MONITORING OF ENCEPHALOPATHY IN LIVER FAILURE. The Lancet 316:8198, pages 783-784.
Crossref
. (1980) Fibreoptic Infections. The Lancet 316:8198, pages 782-783.
Crossref
Giulio Marchesini, Marco Zoli, Cristina Dondi, Lucia Cecchini, Angela Angiolini, Francesco B. Bianchi & Emilio Pisi. (1980) Prevalence of subclinical hepatic encephalopathy in cirrhotics and relationship to plasma amino acid imbalance. Digestive Diseases and Sciences 25:10, pages 763-768.
Crossref
Steven Schenker, Paul V. Desmond, K.V. SpeegJr.Jr. & Anastacio M. HoyumpaJr.Jr.. (1980) Cryptic nature of bromocriptine therapy in portal systemic encephalopathy. Gastroenterology 78:5, pages 1094-1097.
Crossref
Marsha Y. Morgan, Andrew W. Jakobovits, Ian M. James & Sheila Sherlock. (1980) Successful use of bromocriptine in the treatment of chronic hepatic encephalopathy. Gastroenterology 78:4, pages 663-670.
Crossref
Franco Fiaccadori, Florio Ghinelli, Guido Pelosi, Daria Sacchini, Gian Luigi Vaona, Maria Luisa Zeneroli, Emilio Rocchi, Vincenzo Santunione, Paolo Gibertini & Ezio Ventura. (1980) Selective amino acid solutions in hepatic encephalopathy treatment. La Ricerca in Clinica e in Laboratorio 10:2.
Crossref
StephenL. Newman, DanielB. Caplan, VernonM. Camp, BahjatA. Faraj, FaroukM. Ali & PeterA. Ahmann. (1979) PROLACTIN AND THE ENCEPHALOPATHY OF REYE'S SYNDROME. The Lancet 314:8152, pages 1097-1100.
Crossref
J.Howard James, Herbert Freund & Josef E. Fischer. (1979) Amino acids in hepatic encephalopathy. Gastroenterology 77:2, pages 421-423.
Crossref
Giulio Marchesini, Gabriele Forlani, Marco Zoli, Angela Angiolini, Maria P. Scolari, Francesco B. Bianchi & Emilio Pisi. (1979) Insulin and glucagon levels in liver cirrhosis. Digestive Diseases and Sciences 24:8, pages 594-601.
Crossref
Livio Capocaccia, Carlo Cangiano, Antonia Cascino, Vincenzo Calcaterra, Patrizia Cardelli & Filippo Rossi Fanelli. (1979) Influence of phenylethanolamine on octopamine plasma determination in hepatic encephalopathy. Clinica Chimica Acta 93:3, pages 371-376.
Crossref
David W. Kinniburgh & Nigel D. Boyd. (1979) Determination of plasma octopamine and its level in renal disease. Clinical Biochemistry 12:1, pages 27-32.
Crossref
Jay P. Marshall, Telfair H. Parker, Roderick K. Roberts & Steven Schenker. 1979. Biochemistry and Pharmacology of Ethanol. Biochemistry and Pharmacology of Ethanol 479 502 .
Bahjat A. Faraj, Farouk M. Ali, Joseph D. Ansley & Eugene J. Malveaux. (1978) Decarboxylation to tyramine: An important route of tyrosine metabolism in dogs with experimental hepatic encephalopathy. Gastroenterology 75:6, pages 1041-1044.
Crossref
M Y Morgan, J P Milsom & S Sherlock. (1978) Plasma ratio of valine, leucine and isoleucine to phenylalanine and tyrosine in liver disease.. Gut 19:11, pages 1068-1073.
Crossref
Alan A. Boulton. (1978) The tyramines: Functionally significant biogenic amines or metabolic accidents?. Life Sciences 23:7, pages 659-671.
Crossref
Antonia Cascino, Carlo Cangiano, Vincenzo Calcaterra, Filippo Rossi-Fanelli & Livio Capocaccia. (1978) Plasma amino acids imbalance in patients with liver disease. The American Journal of Digestive Diseases 23:7, pages 591-598.
Crossref
C. CANGIANO, F. ROSSI‐FANELLI, A. BOZZI, V. CALCATERRA, A. CASCINO & L. CAPOCACCIA. (2008) Plasma phenylethanolamine in hepatic encephalopathy. European Journal of Clinical Investigation 8:3, pages 183-184.
Crossref
D. A. Durden. 1978. Research Methods in Neurochemistry. Research Methods in Neurochemistry 205 250 .
R. A. CHASE, P. N. TREWBY, M. DAVIS & ROGER WILLIAMS. (2008) Serum octopamine, coma, and charcoal haemoperfusion in fulminant hepatic failure. European Journal of Clinical Investigation 7:5, pages 351-354.
Crossref
Norton J. Greenberger, James Carley, Steven Schenker, Irene Bettinger, Connie Stamnes & Pete Beyer. (1977) Effect of vegetable and animal protein diets in chronic hepatic encephalopathy. The American Journal of Digestive Diseases 22:10, pages 845-855.
Crossref
L Zieve & R L Olsen. (1977) Can hepatic coma be caused by a reduction of brain noradrenaline or dopamine?. Gut 18:9, pages 688-691.
Crossref
Antonio Morelli, Margaret Frintzilas & David S. Zimmon. (1977) Platelet Uptake of Octopamine and Norepinephrine in Hepatic Encephalopathy. Gastroenterology 73:3, pages 560-564.
Crossref
H. Laursen, R. Klysner & A. Geisler. (2008) Adenylate Cyclase Activity in Corpus Striatum of Rats with Porto‐Caval Anastomosis. Acta Physiologica Scandinavica 100:3, pages 282-287.
Crossref
Harvey M. Rosen, Norman Yoshimura, Jane M. Hodgman & Josef E. Fischer. (1977) Plasma Amino Acid Patterns in Hepatic Encephalopathy of Differing Etiology. Gastroenterology 72:3, pages 483-487.
Crossref
L. Capocaccia, C. Cangiano, A.F. Attili, M. Angelico, A. Cascino & F.Rossi Fanelli. (1977) Octopamine and ammonia plasma levels in hepatic encephalopathy. Clinica Chimica Acta 75:1, pages 99-105.
Crossref
J. M. Funovics. 1977. Fortschritte in der parenteralen Ernährung. Fortschritte in der parenteralen Ernährung 113 122 .
PeterB Soeters & JosefE Fischer. (1976) INSULIN, GLUCAGON, AMINOACID IMBALANCE, AND HEPATIC ENCEPHALOPATHY. The Lancet 308:7991, pages 880-882.
Crossref
J. H. James, Jane M. Hodgman, J. M. Funovics & J. E. Fischer. (2006) ALTERATIONS IN BRAIN OCTOPAMINE AND BRAIN TYROSINE FOLLOWING PORTACAVAL ANASTOMOSIS IN RATS. Journal of Neurochemistry 27:1, pages 223-227.
Crossref
Bahjat A. Faraj, Paul A. Bowen, James W. Isaacs, Daniel Rudman & Vernon M. Camp. (1976) Hypertyraminemia in Cirrhotic Patients. New England Journal of Medicine 294:25, pages 1360-1364.
Crossref
F. Rossi-Fanelli, C. Cangiano, A. Attili, M. Angelico, A. Cascino, L. Capocaccia, R. Strom & C. Crifò. (1976) Octopamine plasma levels and hepatic encephalopathy: A re-appraisal of the problem. Clinica Chimica Acta 67:3, pages 255-261.
Crossref
KishuK. Manghani, MichaelR. Lunzer, BarbaraH. Billing & Sheila Sherlock. (1975) URINARY AND SERUM OCTOPAMINE IN PATIENTS WITH PORTAL-SYSTEMIC ENCEPHALOPATHY. The Lancet 306:7942, pages 943-946.
Crossref
Michael A. MoskowitzRichard J. Wurtman. (1975) Catecholamines and Neurologic Diseases. New England Journal of Medicine 293:7, pages 332-338.
Crossref
M J Weston & S P Wilkinson. (1975) Consequences of acute renal failure relevant to hepatic failure. Postgraduate Medical Journal 51:598, pages 486-488.
Crossref
J.Howard James & Josef E. Fischer. (1975) Release of octopamine and α-methyloctopamine by l-dopa. Biochemical Pharmacology 24:10, pages 1099-1101.
Crossref
R. N. Ratnaike, E. P. Hicks & I. G. Hislop. (2008) The Rectal Administration of Lactulose. Australian and New Zealand Journal of Medicine 5:2, pages 137-140.
Crossref
F. Linder, H. G. Borst, W. Brendel, F. W. Eigler, W. Isselhard, F. Largiadèr, J. Schmier, L. Schweiberer, M. Turina & E. WolnerJ. Funovics, J. H. James, J. M. Keane, R. I. C. Wesdorp & J. E. Fischer. 1975. 92. Kongreß der Deutschen Gesellschaft für Chirurgie, München, 7.–10. Mai 1975. 92. Kongreß der Deutschen Gesellschaft für Chirurgie, München, 7.–10. Mai 1975 13 17 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.