5
Views
64
CrossRef citations to date
0
Altmetric
Original Articles

Protease Inhibitors in Acute Human Pancreatitis

Correlation between Biochemical Changes and Clinical Course

&
Pages 779-786 | Received 03 Nov 1983, Accepted 06 Jan 1984, Published online: 30 Apr 2018

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (15)

Xinyu Zhang, Zenghui Li, Wei Liu, Juanjuan Du, Yun Liu, Ningjun Yu, Chao Liu, Mei Zeng & Xiaoming Zhang. (2022) The Complement and Coagulation Cascades Pathway is Associated with Acute Necrotizing Pancreatitis by Genomics and Proteomics Analysis. Journal of Inflammation Research 15, pages 2349-2363.
Read now
H. Yeşim Karasulu, Nevin Oruç, Neslihan Üstündağ-Okur, Derya İlem Özdemir, Zeynep Ay Şenyiğit, Funda Barbet Yılmaz, Makbule Aşıkoğlu, Hayal Özkılıç, Eren Akçiçek, Tamer Güneri & Ömer Özütemiz. (2015) Aprotinin revisited: formulation, characterization, biodistribution and therapeutic potential of new aprotinin microemulsion in acute pancreatitis. Journal of Drug Targeting 23:6, pages 525-537.
Read now
S. Schmid, W. Uhl & M. W. Büchler. (1996) Protease-Antiprotease Interactions and the Rationale for Therapeutic Protease Inhibitors. Scandinavian Journal of Gastroenterology 31:sup219, pages 47-50.
Read now
M. Bergenfeldt, R. Berling & K. Ohlsson. (1994) Levels of Leukocyte Proteases in Plasma and Peritoneal Exudate in Severe, Acute Pancreatitis. Scandinavian Journal of Gastroenterology 29:4, pages 371-375.
Read now
M. H. Jespersen, J. Jensen, L. H. Rasmussen, E. Ejlersen, J. Møller-Petersen & H. U. Sperling-Petersen. (1993) The reference range for complexed α2-macroglobulin human plasma: Development of a new enzyme linked in immunosorbent assay (ELISA) for quantitation of complexed α2-macroglobulin. Scandinavian Journal of Clinical and Laboratory Investigation 53:6, pages 639-648.
Read now
Å. Lasson, R. Berling, J. Göransson & K Ohlsson. (1991) Alpha-2-macroglobulin decreases parallel to albumin and haemoglobin after elective surgery. Scandinavian Journal of Clinical and Laboratory Investigation 51:3, pages 225-233.
Read now
K. Ohlsson, R. Olsson, P. Björk, G. Balldin, A. Borgström, Å. Lasson, T. Kohno & R. C. Thompson. (1989) Local Administration of Human Pancreatic Secretory Trypsin Inhibitor Prevents the Development of Experimental Acute Pancreatitis in Rats and Dogs. Scandinavian Journal of Gastroenterology 24:6, pages 693-704.
Read now
Å. Lasson & K. Ohlsson. (1987) Pancreatic Pseudocysts: A Biochemical Evaluation of Proteases and Protease Inhibitors in Plasma. Scandinavian Journal of Gastroenterology 22:3, pages 355-361.
Read now
O. J. Rämö, H. Kiviniemi & P. Jalovaara. (1987) Long-Term Ethanol Ingestion Does Not Increase the Toxicity of Peritoneal Exudate Generated during Acute Haemorrhagic Pancreatitis in Rats. Scandinavian Journal of Gastroenterology 22:10, pages 1165-1168.
Read now
Bertil Sjölund, Åke Lasson & Kjell Ohlsson. (1987) The elimination of trypsin-α-macroglobulin complexes from the blood circulation in pigs during acute pancreatitis and after massive intravenous trypsin infusion. Scandinavian Journal of Clinical and Laboratory Investigation 47:2, pages 131-141.
Read now
Å. Lasson & K. Ohlsson. (1986) Disseminated Intravascular Coagulation and Antiprotease Activity in Acute Human Pancreatitis. Scandinavian Journal of Gastroenterology 21:sup126, pages 35-39.
Read now
A. Lehtola. (1986) Peritoneal Blood Flow during Acute Experimental Pancreatitis: The Role of Peritoneal Exudate. Scandinavian Journal of Gastroenterology 21:6, pages 756-760.
Read now
O. J. Rämö, H. Kiviniemi & P. Jalovaara. (1986) The Composition of Diet in Conjunction with Chronic Ethanol Consumption Alters Plasma Proteinase Inhibitor Levels in Rats. Scandinavian Journal of Gastroenterology 21:6, pages 718-722.
Read now
Å. Lasson, A. Borgström & K. Ohlsson. (1986) Elevated Pancreatic Secretory Trypsin Inhibitor Levels during Severe Inflammatory Disease, Renal Insufficiency, and after Various Surgical Procedures. Scandinavian Journal of Gastroenterology 21:10, pages 1275-1280.
Read now
Åke Lasson & Kjell Ohlsson. (1984) Acute Pancreatitis. Scandinavian Journal of Gastroenterology 19:6, pages 707-710.
Read now

Articles from other publishers (49)

Elisa Bannone, Alessandra Pulvirenti, Giovanni Marchegiani, Pier Giuseppe Vacca, Alessio Marchetti, Alice Cattelani, Roberto Salvia & Claudio Bassi. (2023) No role for protease inhibitors as a mitigation strategy for postpancreatectomy acute pancreatitis (PPAP): Propensity score matching analysis. Pancreatology 23:8, pages 904-910.
Crossref
Annina N. Jandel, Romy M. Heilmann, Henri Sander, Jörg M. Steiner, Niels Grützner & Panagiotis G. Xenoulis. (2023) Serum α1-Proteinase Inhibitor, Calprotectin, and S100A12 Concentrations in the Characterization of Pancreatitis in Dogs. Veterinary Sciences 10:7, pages 428.
Crossref
Soon-Won Choi, Yoon-Hwan Kim, Min Soo Kang, Yunho Jeong, Jin-Ok Ahn, Jung Hoon Choi & Jin-Young Chung. (2021) Serum Concentration of Inflammatory Cytokines in Dogs with Suspected Acute Pancreatitis. Veterinary Sciences 8:3, pages 51.
Crossref
C. Mansfield & T. Beths. (2015) Management of acute pancreatitis in dogs: a critical appraisal with focus on feeding and analgesia. Journal of Small Animal Practice 56:1, pages 27-39.
Crossref
Caroline Mansfield. (2012) Pathophysiology of Acute Pancreatitis: Potential Application from Experimental Models and Human Medicine to Dogs. Journal of Veterinary Internal Medicine 26:4, pages 875-887.
Crossref
Caroline S. MansfieldGarry A. AndersonAmanda J. O’Hara. (2012) Association between canine pancreatic-specific lipase and histologic exocrine pancreatic inflammation in dogs. Journal of Veterinary Diagnostic Investigation 24:2, pages 312-318.
Crossref
Edwin C. Thrower, Alexander P. E. Diaz de Villalvilla, Thomas R. Kolodecik & Fred S. Gorelick. (2006) Zymogen activation in a reconstituted pancreatic acinar cell system. American Journal of Physiology-Gastrointestinal and Liver Physiology 290:5, pages G894-G902.
Crossref
Eric M. Walser, William H. Nealon, Santiago Marroquin, Syed Raza, J. Alberto Hernandez & James Vasek. (2005) Sterile Fluid Collections in Acute Pancreatitis: Catheter Drainage Versus Simple Aspiration. CardioVascular and Interventional Radiology 29:1, pages 102-107.
Crossref
C Wilson, A Heads, A Shenkin & C W Imrie. (1989) C-reactive protein, antiproteases and complement factors as objective markers of severity in acute pancreatitis. British Journal of Surgery 76:2, pages 177-181.
Crossref
C Wilson, A Shenkin & C Imrie. (1991) Role of the protease-antiprotease balance in peritoneal exudate during acute pancreatitis. British Journal of Surgery 78:1, pages 78-81.
Crossref
Walter Halangk & Markus M. Lerch. (2005) Early Events in Acute Pancreatitis. Clinics in Laboratory Medicine 25:1, pages 1-15.
Crossref
J. Mayerle, F. U. Weiss & M. M. Lerch. 2005. Pancreatitis: Advances in Pathobiology, Diagnosis and Treatment. Pancreatitis: Advances in Pathobiology, Diagnosis and Treatment 13 27 .
Walter Halangk & Markus M. Lerch. (2004) Early events in acute pancreatitis. Gastroenterology Clinics of North America 33:4, pages 717-731.
Crossref
C. D. Johnson & C. W. ImrieMarkus M. Lerch, Manuel Ruthenbürger, Frank Ch. Mooren, Verena Hlouschek, Julia Mayerle, Peter Simon & F. Ulrich Weiss. 2004. Pancreatic Disease. Pancreatic Disease 324 339 .
Jennifer L. Holm, Daniel L. Chan & Elizabeth A. Rozanski. (2003) Acute pancreatitis in dogs. Journal of Veterinary Emergency and Critical Care 13:4, pages 201-213.
Crossref
Markus M. Lerch, Elke Albrecht, Manuel Ruthenbürger, Julia Mayerle, Walter Halangk & Burkhard Krüger. (2003) Pathophysiology of Alcohol-Induced Pancreatitis. Pancreas 27:4, pages 291-296.
Crossref
Caroline S. Mansfield, Boyd R. Jones & T. Spillman. (2003) Assessing the severity of canine pancreatitis. Research in Veterinary Science 74:2, pages 137-144.
Crossref
S. Grulke, M. Gangl, G. Deby-dupont, I. Caudron, C. Deby & D. Serteyn. (2002) Plasma Trypsin Level in Horses Suffering From Acute Intestinal Obstruction. The Veterinary Journal 163:3, pages 283-291.
Crossref
Zhao Lu, Suresh Karne, Thomas Kolodecik & Fred S. Gorelick. (2002) Alcohols enhance caerulein-induced zymogen activation in pancreatic acinar cells. American Journal of Physiology-Gastrointestinal and Liver Physiology 282:3, pages G501-G507.
Crossref
John M. Howard & Walter HessJohn M. Howard & Walter Hess. 2002. History of the Pancreas: Mysteries of a Hidden Organ. History of the Pancreas: Mysteries of a Hidden Organ 165 260 .
Markus M. Lerch, Walter Halangk & Burkhard Krüger. 2002. Cellular Peptidases in Immune Functions and Diseases 2. Cellular Peptidases in Immune Functions and Diseases 2 403 410 .
CS Mansfield & BR Jones. (2016) Review of Feline Pancreatitis Part Two: Clinical Signs, Diagnosis and Treatment. Journal of Feline Medicine and Surgery 3:3, pages 125-132.
Crossref
CS Mansfield & BR Jones. (2016) Review of Feline Pancreatitis Part One: The Normal Feline Pancreas, the Pathophysiology, Classification, Prevalence and Aetiologies of Pancreatitis. Journal of Feline Medicine and Surgery 3:3, pages 117-124.
Crossref
Werner HartwigJens WernerRamon E. JimenezKaspar Z'graggenJörg Weimann, Kent B. Lewandrowski, Andrew L. WarshawCarlos Fernández-Del Castillo. (1999) Trypsin and activation of circulating trypsinogen contribute to pancreatitis-associated lung injury. American Journal of Physiology-Gastrointestinal and Liver Physiology 277:5, pages G1008-G1016.
Crossref
Suresh Karne & Fred S. Gorelick. (1999) ETIOPATHOGENESIS OF ACUTE PANCREATITIS. Surgical Clinics of North America 79:4, pages 699-710.
Crossref
Klaus Mergener & John Baillie. (2016) The Role of ERCP in Gallstone Pancreatitis. Journal of Intensive Care Medicine 14:2, pages 74-85.
Crossref
Klaus Mergener & John Baillie. (1999) The Role of ERCP in Gallstone Pancreatitis. Journal of Intensive Care Medicine 14:2, pages 74-85.
Crossref
Steven C. Kazmierczak. 1997. Clinical Pathology of Pancreatic Disorders. Clinical Pathology of Pancreatic Disorders 75 124 .
Atilla Ertan, Mary Schwartz & Alfredo Rabassa. (1996) Response by Drs. Ertan, Schwartz, and Rabassa. Digestive Diseases and Sciences 41:3, pages 550-551.
Crossref
Alfredo A. Rabassa, Mary R. Schwartz & Atilla Ertan. (1995) β1-Antitrypsin deficiency and chronic pancreatitis. Digestive Diseases and Sciences 40:9, pages 1997-2001.
Crossref
D. A. Williams. (2008) Diagnosis and management of pancreatitis. Journal of Small Animal Practice 35:9, pages 445-454.
Crossref
Andrew L. Warshaw. (1993) Damage prevention versus damage control in acute pancreatitis. Gastroenterology 104:4, pages 1216-1219.
Crossref
Michael Larvin, David J. Alexander, Stanislaus F. Switala & Michael J. McMahon. (1993) Impaired mononuclear phagocyte function in patients with severe acute pancreatitis: Evidence from studies of plasma clearance of trypsin and monocyte phagocytosis. Digestive Diseases and Sciences 38:1, pages 18-27.
Crossref
Everett J. Mozell, Eugene A. Woltering & Thomas M. O'Dorisio. (1991) Non-endocrine applications of somatostatin and octreotide acetate: facts and flights of fancy. Disease-a-Month 37:12, pages 749-810.
Crossref
P S Haber, J S Wilson, B H McGarity, W Hall, M C Thomas & R C Pirola. (1991) Alpha 1 antitrypsin phenotypes and alcoholic pancreatitis.. Gut 32:8, pages 945-948.
Crossref
S. E. J. Edmunds & M. L. Wilkinson. (2008) Alpha 1‐antitrypsin deficiency and pancreatitis in a juvenile. Australian and New Zealand Journal of Medicine 21:3, pages 345-347.
Crossref
R E Banks, S W Evans, D Alexander, F Van Leuven, J T Whicher & M J McMahon. (1991) Alpha 2 macroglobulin state in acute pancreatitis. Raised values of alpha 2 macroglobulin-protease complexes in severe and mild attacks.. Gut 32:4, pages 430-434.
Crossref
K. Ohlsson & S. Genell. 1991. Pancreatic Disease. Pancreatic Disease 213 226 .
Peter K. Donnelly, Philip Trotter, Michael White & Brian K. Shenton. (1990) Immunoelectrophoretic pattern of α2-macroglobulin and α2-macroglobulin-protease complexes. Clinica Chimica Acta 195:1-2, pages 87-92.
Crossref
A. BENGTSSON, J.‐P. BENGTSON, Å. RYDENHAG, L. ROXVALL & M. HEIDEMAN. (2009) Accumulation of anaphylatoxins and terminal complement complexes in inflammatory fluids. Journal of Internal Medicine 228:2, pages 173-176.
Crossref
. (1988) Pancreatic Society of Great Britain and Ireland. 12th annual meeting. 6 November, 1987. Abstracts.. Gut 29:2, pages A265-A272.
Crossref
Åke Lasson, Magnus Delshammar & Kjell Ohlsson. 1988. Proteases II. Proteases II 433 440 .
TETSUO HAYAKAWA, TOSHIYUKI MURASE, TAKAHARU KONDO, TOKIMUNE SHIBATA, YOSHIYUKI SUGIMOTO & MOTOJI KITAGAWA. (2008) Serum pancreatic secretory trypsin inhibitor in pancreatic diseases. Journal of Gastroenterology and Hepatology 2:4, pages 301-307.
Crossref
Michael A. Dubick, A. David Mayer, Adhip P. N. Majumdar, Gregory Mar, Michael J. McMahon & Michael C. Geokas. (1987) Biochemical studies in peritoneal fluid from patients with acute pancreatitis. Digestive Diseases and Sciences 32:3, pages 305-312.
Crossref
I.William Browder, Edward Sherwood, David Williams, Emest Jones, Rose McNamee & Nicholas DiLuzio. (1987) Protective effect of glucan-enhanced macrophage function in experimental pancreatitis. The American Journal of Surgery 153:1, pages 25-33.
Crossref
M. V. Singer & H. Goebell. 1987. Acute Pancreatitis. Acute Pancreatitis 272 277 .
Åke Lasson, Anders Borgström & Kjell Ohlsson. (1986) Serum levels of immunoreactive PSTI in acute abdominal disorders, with special reference to a possible extrapancreatic PSTI production. Clinica Chimica Acta 161:1, pages 37-46.
Crossref
C. Largman, R. D. Reidelberger & H. Tsukamoto. (1986) Correlation of trypsin-plasma inhibitor complexes with mortality in experimental pancreatitis in rats. Digestive Diseases and Sciences 31:9, pages 961-969.
Crossref
M. Büchler, P. Malfertheiner & H. G. Beger. 1986. Diagnostic Procedures in Pancreatic Disease. Diagnostic Procedures in Pancreatic Disease 123 129 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.