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Original Articles

Faecal Steroids and Colorectal Carcinogenesis

Pages 76-82 | Published online: 01 Apr 2016

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (7)

Saeede Jafari Nasab, Alireza Bahrami, Pegah Rafiee, Azita Hekmatdoust, Matin Ghanavati, Bahram Rashidkhani, Amir Sadeghi, Hamid Asadzadeh Aghdaei, Farah Naja & Ehsan Hejazi. (2020) Healthy Eating Index-2010 and Mediterranean-Style Dietary Pattern Score and the risk of colorectal cancer and adenoma: a case–control study. Nutrition and Cancer 72:8, pages 1326-1335.
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Daniel Demeyer, Birgit Mertens, Stefaan De Smet & Michèle Ulens. (2016) Mechanisms Linking Colorectal Cancer to the Consumption of (Processed) Red Meat: A Review. Critical Reviews in Food Science and Nutrition 56:16, pages 2747-2766.
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BhaumikB. Patel & AdhipP. N. Majumdar. (2009) Synergistic Role of Curcumin With Current Therapeutics in Colorectal Cancer: Minireview. Nutrition and Cancer 61:6, pages 842-846.
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Sarasija Suresh, Vivek R. Yadav & Anand Suresh. (2006) Health Benefits and Therapeutic Applications of Curcumin. Clinical Research and Regulatory Affairs 23:3-4, pages 191-210.
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I.A. Brownlee, A. Allen, J.P. Pearson, P.W. Dettmar, M.E. Havler, M.R. Atherton & E. Onsøyen. (2005) Alginate as a Source of Dietary Fiber. Critical Reviews in Food Science and Nutrition 45:6, pages 497-510.
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Pascale Lepercq, Philippe Gérard, Fabienne Béguet, Jean-pierre Grill, Purification Relano, Chantal Cayuela & Catherine Juste. (2004) Isolates from normal human intestinal flora but not lactic acid bacteria exhibit 7α- and 7β-hydroxysteroid dehydrogenase activities. Microbial Ecology in Health and Disease 16:4, pages 195-201.
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Articles from other publishers (35)

Saeede Jafari Nasab, Cain C. T. Clark & Mohammadhasan Entezari. (2023) Mediterranean diet and colorectal adenomas: a systematic review and meta-analysis of observational studies. European Journal of Cancer Prevention.
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Seung Yun Lee, Da Young Lee, Ji Hyeop Kang, Jae Hyeon Kim, Jae Won Jeong, Hyun Woo Kim, Dong Hoon Oh, Seung Hyeon Yoon & Sun Jin Hur. (2022) Relationship between gut microbiota and colorectal cancer: Probiotics as a potential strategy for prevention. Food Research International 156, pages 111327.
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Fenglian Ma, Mengying Sun, Yinglong Song, Arong Wang, Shujuan Jiang, Fang Qian, Guangqing Mu & Yanfeng Tuo. (2022) Lactiplantibacillus plantarum-12 Alleviates Inflammation and Colon Cancer Symptoms in AOM/DSS-Treated Mice through Modulating the Intestinal Microbiome and Metabolome. Nutrients 14:9, pages 1916.
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Pegah Rafiee, Nitin Shivappa, James R. Hébert, Saeede Jaafari Nasab, Alireza Bahrami, Azita Hekmatdoost, Bahram Rashidkhani, Amir Sadeghi, Mohammad Houshyari & Ehsan Hejazi. (2019) Dietary Inflammatory Index and Odds of Colorectal Cancer and Colorectal Adenomatous Polyps in a Case-Control Study from Iran. Nutrients 11:6, pages 1213.
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Muhammad Imran, Muhammad Nadeem, Syed Amir Gilani, Shaista Khan, Muhammad Wasim Sajid & Rai Muhammad Amir. (2018) Antitumor Perspectives of Oleuropein and Its Metabolite Hydroxytyrosol: Recent Updates. Journal of Food Science 83:7, pages 1781-1791.
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Qingchao Zhu, Renyuan Gao, Wen Wu & Huanlong Qin. (2013) The role of gut microbiota in the pathogenesis of colorectal cancer. Tumor Biology 34:3, pages 1285-1300.
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Annemarie Boleij & Harold Tjalsma. (2012) Gut bacteria in health and disease: a survey on the interface between intestinal microbiology and colorectal cancer. Biological Reviews 87:3, pages 701-730.
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Umang Munjal, Michael Glei, Beatrice Louise Pool-Zobel & Daniel Scharlau. (2009) Fermentation products of inulin-type fructans reduce proliferation and induce apoptosis in human colon tumour cells of different stages of carcinogenesis. British Journal of Nutrition 102:5, pages 663-671.
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Masanobu Kawanishi, Hiroshi Nishida, Yukari Totsuka, Koichi Nishimura, Keiji Wakabayashi & Takashi Yagi. (2009) Mutagenic Specificity of N-Nitrosotaurocholic Acid in supF Shuttle Vector Plasmids. Genes and Environment 31:1, pages 9-14.
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Hye-Young SungYoung-Sun Choi. (2008) Fructooligosaccharide and Soy Isoflavone Suppress Colonic Aberrant Crypt Foci and Cyclooxygenase-2 Expression in Dimethylhydrazine-Treated Rats. Journal of Medicinal Food 11:1, pages 78-85.
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Frank Grünhage, Matthias Jungck, Christoph Lamberti, Christine Berg, Ursula Becker, Hildegard Schulte-Witte, Dominik Plassmann, Nils Rahner, Stefan Aretz, Nicolaus Friedrichs, Reinhard Buettner, Tilman Sauerbruch & Frank Lammert. (2007) Association of familial colorectal cancer with variants in the E-cadherin (CDH1) and cyclin D1 (CCND1) genes. International Journal of Colorectal Disease 23:2, pages 147-154.
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Ping Su, Anders Henriksson & Hazel Mitchell. (2007) Selected prebiotics support the growth of probiotic mono-cultures in vitro. Anaerobe 13:3-4, pages 134-139.
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Patricia Heavey, Ian Rowland & Joseph Rafter. 2006. Gastrointestinal Microbiology. Gastrointestinal Microbiology 225 236 .
Barbora Drzikova, Gerhard Dongowski & Erich Gebhardt. (2007) Dietary fibre-rich oat-based products affect serum lipids, microbiota, formation of short-chain fatty acids and steroids in rats. British Journal of Nutrition 94:6, pages 1012-1025.
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David W. Scott, Sophia Mutamba, Robin G. Hopkins & George Loo. (2005) Increased GADD gene expression in human colon epithelial cells exposed to deoxycholate. Journal of Cellular Physiology 202:1, pages 295-303.
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Sabine Sembries, Gerhard Dongowski, Katri Mehrländer, Frank Will & Helmut Dietrich. (2004) Dietary fiber–rich colloids from apple pomace extraction juices do not affect food intake and blood serum lipid levels, but enhance fecal excretion of steroids in rats. The Journal of Nutritional Biochemistry 15:5, pages 296-302.
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Y. Bouhnik, C. Neut, L. Raskine, C. Michel, M. Riottot, C. Andrieux, F. Guillemot, F. Dyard & B. Flourié. (2004) Prospective, randomized, parallel-group trial to evaluate the effects of lactulose and polyethylene glycol-4000 on colonic flora in chronic idiopathic constipation. Alimentary Pharmacology & Therapeutics 19:8, pages 889-899.
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Patricia M Heavey & Ian R Rowland. (2004) Gastrointestinal cancer. Best Practice & Research Clinical Gastroenterology 18:2, pages 323-336.
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Y Bouhnik, A Attar, F A Joly, M Riottot, F Dyard & B Flourié. (2004) Lactulose ingestion increases faecal bifidobacterial counts: A randomised double-blind study in healthy humans. European Journal of Clinical Nutrition 58:3, pages 462-466.
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Amanda J. Cross & Rashmi Sinha. (2004) Meat-related mutagens/carcinogens in the etiology of colorectal cancer. Environmental and Molecular Mutagenesis 44:1, pages 44-55.
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Gerhard Dongowski, Mario Huth & Erich Gebhardt. (2007) Steroids in the intestinal tract of rats are affected by dietary-fibre-rich barley-based diets. British Journal of Nutrition 90:5, pages 895-906.
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R. Huges & I. Rowland. 2003. Gut Flora, Nutrition, Immunity and Health. Gut Flora, Nutrition, Immunity and Health 208 236 .
Iain A. Brownlee, Mike E. Havler, Peter W. Dettmar, Adrian Allen & Jeffrey P. Pearson. (2007) Colonic mucus: secretion and turnover in relation to dietary fibre intake. Proceedings of the Nutrition Society 62:1, pages 245-249.
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Alicia Navarro, María P Díaz, Sonia E Muñoz, María J Lantieri & Aldo R Eynard. (2003) Characterization of meat consumption and risk of colorectal cancer in Cordoba, Argentina. Nutrition 19:1, pages 7-10.
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F. Kullmann. 2003. Chronisch entzündliche Darmerkrankungen. Chronisch entzündliche Darmerkrankungen 81 99 .
Gerhard Dongowski, Mario Huth, Erich Gebhardt & Wilhelm Flamme. (2002) Dietary Fiber-Rich Barley Products Beneficially Affect the Intestinal Tract of Rats. The Journal of Nutrition 132:12, pages 3704-3714.
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P R Debruyne, E A Bruyneel, I-M Karaguni, Xd Li, G Flatau, O Müller, A Zimber, C Gespach & M M Mareel. (2002) Bile acids stimulate invasion and haptotaxis in human colorectal cancer cells through activation of multiple oncogenic signaling pathways. Oncogene 21:44, pages 6740-6750.
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Julian Little, Robert W. Owen, Fresie Fernandez, Patricia G. Hawtin, Michael J. Hill, Richard F. A. Logan, Michael H. Thompson & Jack D. Hardcastle. (2002) Asymptomatic Colorectal Neoplasia and Fecal Characteristics. Diseases of the Colon & Rectum 45:9, pages 1233-1241.
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V Costarelli, T J Key, P N Appleby, D S Allen, I S Fentiman & T A B Sanders. (2002) A prospective study of serum bile acid concentrations and colorectal cancer risk in post-menopausal women on the island of Guernsey. British Journal of Cancer 86:11, pages 1741-1744.
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Philip R. Debruyne, Erik A. Bruyneel, Xuedong Li, Amazia Zimber, Christian Gespach & Marc M. Mareel. (2001) The role of bile acids in carcinogenesis. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 480-481, pages 359-369.
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Anna Powolny, Jing Xu & George Loo. (2001) Deoxycholate induces DNA damage and apoptosis in human colon epithelial cells expressing either mutant or wild-type p53. The International Journal of Biochemistry & Cell Biology 33:2, pages 193-203.
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M. Stoneham. (2000) Olive oil, diet and colorectal cancer: an ecological study and a hypothesis. Journal of Epidemiology & Community Health 54:10, pages 756-760.
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A Haines, M J Hill, M H Thompson, R W Owen, R E O Williams, T W Meade, H Wilkes & M Griffin. (2000) A prospective study of faecal bile acids and colorectal cancer. European Journal of Cancer Prevention 9:5, pages 317-324.
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John Birkbeck. 1999. Medical Importance of the Normal Microflora. Medical Importance of the Normal Microflora 262 294 .
M.F. Chaplin. (2016) Review : Bile acids, fibre and colon cancer: the story unfolds. Journal of the Royal Society of Health 118:1, pages 53-61.
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