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Scandinavian Journal of Gastroenterology Volume 54, 2019 - Issue 5
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Original Article

Efficacy and safety of curcumin in primary sclerosing cholangitis: an open label pilot study

John E. EatonDivision of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA; Correspondence[email protected]
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,
Kevin M. NelsonDivision of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA; View further author information
,
Andrea A. GossardDivision of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA; View further author information
,
Elizabeth J. CareyDepartment of Gastroenterology and Hepatology, Arizona State University College of Health Solutions, Phoenix, AZ, USA; View further author information
,
James H TabibianDivision of Gastroenterology, Department of Medicine, Olive View-UCLA Medical Center, Sylmar, CA, USAView further author information
,
Keith D. LindorDepartment of Gastroenterology and Hepatology, Arizona State University College of Health Solutions, Phoenix, AZ, USA; View further author information
&
Nicholas F. LaRussoDivision of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA; View further author information
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Pages 633-639 | Received 04 Feb 2019, Accepted 22 Apr 2019, Published online: 26 May 2019

Citations (21)

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Minxiao Chen, Chenchen Qian, Bo Jin, Chenghong Hu, Lingxi Zhang, Minshan Wang, Bin Zhou, Wei Zuo, Lijiang Huang & Yi Wang. (2023) Curcumin analog WZ26 induces ROS and cell death via inhibition of STAT3 in cholangiocarcinoma. Cancer Biology & Therapy 24:1.
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Ahmad Hassan Ali, Jennifer Damman, Shamita B. Shah, Yinka Davies, Melissa Hurwitz, Mariam Stephen, Leta M. Lemos, Elizabeth J. Carey, Keith D. Lindor, Cynthia W. Buness, Leina Alrabadi, William E. Berquist & Kenneth L. Cox. (2020) Open-label prospective therapeutic clinical trials: oral vancomycin in children and adults with primary sclerosing cholangitis. Scandinavian Journal of Gastroenterology 55:8, pages 941-950.
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Articles from other publishers (19)

William H. Wheless & Mark W. Russo. (2024) Treatment of Primary Sclerosing Cholangitis Including Transplantation. Clinics in Liver Disease 28:1, pages 171-182.
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Ajaikumar B. Kunnumakkara, Mangala Hegde, Dey Parama, Sosmitha Girisa, Aviral Kumar, Uzini Devi Daimary, Prachi Garodia, Sarat Chandra Yenisetti, Oommen V. Oommen & Bharat B. Aggarwal. (2023) Role of Turmeric and Curcumin in Prevention and Treatment of Chronic Diseases: Lessons Learned from Clinical Trials. ACS Pharmacology & Translational Science 6:4, pages 447-518.
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Timothy M. Panknin, Carol L. Howe, Meg Hauer, Bhanu Bucchireddigari, Anthony M. Rossi & Janet L. Funk. (2023) Curcumin Supplementation and Human Disease: A Scoping Review of Clinical Trials. International Journal of Molecular Sciences 24:5, pages 4476.
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Kamal D. Moudgil & Shivaprasad H. Venkatesha. (2022) The Anti-Inflammatory and Immunomodulatory Activities of Natural Products to Control Autoimmune Inflammation. International Journal of Molecular Sciences 24:1, pages 95.
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Ganesan Padmini Tamilarasi, Manikandan Krishnan, Govindaraj Sabarees, Siddan Gouthaman, Veerachamy Alagarsamy & Viswas Raja Solomon. (2022) Emerging Trends in Curcumin Embedded Electrospun Nanofibers for Impaired Diabetic Wound Healing. Applied Nano 3:4, pages 202-232.
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Michael Trauner & Claudia Daniela Fuchs. (2022) Novel therapeutic targets for cholestatic and fatty liver disease. Gut 71:1, pages 194-209.
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Yongli Li, Junjie Jiao, Yuanzheng Qi, Wanqi Yu, Shihui Yang, Jingjie Zhang & Jinghui Zhao. (2021) Curcumin: A review of experimental studies and mechanisms related to periodontitis treatment. Journal of Periodontal Research 56:5, pages 837-847.
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Hasriadi, Peththa Wadu Dasuni Wasana, Opa Vajragupta, Pornchai Rojsitthisak & Pasarapa Towiwat. (2021) Mechanistic Insight into the Effects of Curcumin on Neuroinflammation-Driven Chronic Pain. Pharmaceuticals 14:8, pages 777.
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Arghavan Memarzia, Mohammad R. Khazdair, Sepideh Behrouz, Zahra Gholamnezhad, Maryam Jafarnezhad, Saeideh Saadat & Mohammad H. Boskabady. (2021) Experimental and clinical reports on anti‐inflammatory, antioxidant, and immunomodulatory effects of Curcuma longa and curcumin, an updated and comprehensive review . BioFactors 47:3, pages 311-350.
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Marta Mazzetti, Giulia Marconi, Martina Mancinelli, Antonio Benedetti, Marco Marzioni & Luca Maroni. (2021) The Management of Cholestatic Liver Diseases: Current Therapies and Emerging New Possibilities. Journal of Clinical Medicine 10:8, pages 1763.
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Mengzhi Zou, Aizhen Wang, Jiajie Wei, Heng Cai, Zixun Yu, Luyong Zhang & Xinzhi Wang. (2021) An insight into the mechanism and molecular basis of dysfunctional immune response involved in cholestasis. International Immunopharmacology 92, pages 107328.
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Renald Blundell & Joseph Ignatius Azzopardi. 2021. Influence of Nutrients, Bioactive Compounds, and Plant Extracts in Liver Diseases. Influence of Nutrients, Bioactive Compounds, and Plant Extracts in Liver Diseases 129 139 .
Kambiz Hassanzadeh, Lucia Buccarello, Jessica Dragotto, Asadollah Mohammadi, Massimo Corbo & Marco Feligioni. (2020) Obstacles against the Marketing of Curcumin as a Drug. International Journal of Molecular Sciences 21:18, pages 6619.
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Adam P. Buckholz & Robert S. BrownJr.Jr.. (2020) Cholangiocarcinoma. Clinics in Liver Disease 24:3, pages 421-436.
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Elisa Ceccherini, Antonella Cecchettini, Maria Aurora Morales & Silvia Rocchiccioli. (2020) The Potentiality of Herbal Remedies in Primary Sclerosing Cholangitis: From In Vitro to Clinical Studies. Frontiers in Pharmacology 11.
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Ayesha ShahGraeme A. MacdonaldMark MorrisonGerald Holtmann. (2020) Targeting the Gut Microbiome as a Treatment for Primary Sclerosing Cholangitis: A Conceptional Framework. American Journal of Gastroenterology 115:6, pages 814-822.
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Brian M. Fung & James H. Tabibian. (2020) Cholangiocarcinoma in patients with primary sclerosing cholangitis. Current Opinion in Gastroenterology 36:2, pages 77-84.
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Masoud Nouri-Vaskeh, Hossein Afshan, Aida Malek Mahdavi, Leila Alizadeh, Xiude Fan & Mohammad Zarei. (2020) Curcumin ameliorates health-related quality of life in patients with liver cirrhosis: A randomized, double-blind placebo-controlled trial. Complementary Therapies in Medicine 49, pages 102351.
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Vollono Laura, Falconi Mattia, Gaziano Roberta, Iacovelli Federico, Dika Emi, Terracciano Chiara, Bianchi Luca & Campione Elena. (2019) Potential of Curcumin in Skin Disorders. Nutrients 11:9, pages 2169.
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