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Scandinavian Journal of Gastroenterology Volume 54, 2019 - Issue 10
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Original Article

Rate of non-response to ursodeoxycholic acid in a large real-world cohort of primary biliary cholangitis patients in Italy

Umberto Vespasiani-GentilucciInternal Medicine and Hepatology, University Campus Bio-Medico of Rome, Rome, Italy; Correspondence[email protected]
,
Floriano RosinaMedical Team Torino, Torino, Italy;
,
Valeria Pace-PalittiASL Pescara, Pescara, Italy;
,
Rodolfo SaccoDepartment of Gastroenterology, University Hospital, Pisa, Italy;
,
Adriano PellicelliLiver Unit, San Camillo Hospital, Roma, Italy;
,
Luchino ChessaLiver Unit, University Hospital of Cagliari, Cagliari, Italy; ORCID Iconhttp://orcid.org/0000-0002-9474-0995
ORCID Icon,
Antonio De VincentisInternal Medicine and Hepatology, University Campus Bio-Medico of Rome, Rome, Italy;
,
Michela BarlattaniASL RM A, Rome, Italy;
,
Angelo BarlattaniASL RM A, Rome, Italy;
,
Valentina FelettiGastroenterology Unit, Santa Maria Delle Croci Hospital, Ravenna, Italy;
,
Alessandro MussettoGastroenterology Unit, Santa Maria Delle Croci Hospital, Ravenna, Italy;
,
Teresa ZolfinoDepartment of Gastroenterology, Brotzu Hospital, Cagliari, Italy;
,
Maurizio RusselloLiver Unit, Arnas Garibaldi, Catania, Italy;
,
Raffaele CozzolongoGastroenterology Unit, National Institute of Gastroenterology “S de Bellis” Reseach Hospital, Castellana Grotte (Bari), Italy;
,
Giovanni GarrucciuGeneral Medicine and Medical Pathology, Sassari University Hospital, Sassari, Italy;
,
Grazia NiroDepartment of Gastroenterology, Casa Sollievo Della Sofferenza Institute, San Giovanni Rotondo (Foggia), Italy;
,
Donato BaccaInternal Medicine Unit, Casarano Hospital, Lecce, Italy;
,
Gaetano BertinoDepartment of Hepatology, University Hospital Policlinico Vittorio Emanuele, Catania, Italy;
,
Ernesto ClaarDepartment of Hepatology, Betania Hospital, Napoli, Italy;
,
Antonio AscioneDepartment of Hepatology, Fatebenefratelli Hospital, Napoli, Italy;
,
Giuseppe D’AdamoDepartment of General Medicine, Umberto I Hospital ASL Salerno, Nocera Inferiore, Italy;
,
Luigi Elio AdinolfiDepartment of Internal Medicine, Luigi Vanvitelli University of Campania, Napoli, Italy; ORCID Iconhttp://orcid.org/0000-0001-8453-4912
ORCID Icon,
Gaetano ScifoDepartment of Infectious Diseases, Umberto I Hospital, Siracusa, Italy;
,
Antonio IzziDepartment of Infectious Diseases, D. Cotugno Hospital, Napoli, Italy
& for the CLEO-AIGO PBC study group show all
Pages 1274-1282 | Received 11 Jun 2019, Accepted 08 Sep 2019, Published online: 28 Sep 2019

Citations (11)

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Lin-Xiang Huang, Zi-Long Wang, Rui Jin, Hong-Song Chen & Bo Feng. (2022) Incomplete response to ursodeoxycholic acid in primary biliary cholangitis: criteria, epidemiology, and possible mechanisms. Expert Review of Gastroenterology & Hepatology 16:11-12, pages 1065-1078.
Read now
Rakesh Sahu, Rakhi Mishra & Chandana Majee. (2020) An insight into primary biliary cholangitis and its recent advances in treatment: semi-synthetic analogs to combat ursodeoxycholic-acid resistance. Expert Review of Gastroenterology & Hepatology 14:10, pages 985-998.
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Mohammad Almeqdadi & Fredric D. Gordon. (2024) Farnesoid X Receptor Agonists: A Promising Therapeutic Strategy for Gastrointestinal Diseases. Gastro Hep Advances 3:3, pages 344-352.
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Naruhiro Kimura, Kazuya Takahashi, Toru Setsu, Shu Goto, Suguru Miida, Nobutaka Takeda, Yuichi Kojima, Yoshihisa Arao, Kazunao Hayashi, Norihiro Sakai, Yusuke Watanabe, Hiroyuki Abe, Hiroteru Kamimura, Akira Sakamaki, Takeshi Yokoo, Kenya Kamimura, Atsunori Tsuchiya & Shuji Terai. (2023) Machine learning prediction model for treatment responders in patients with primary biliary cholangitis. JGH Open 7:6, pages 431-438.
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Dong Xiang, Yanan Liu, Yue Zu, Jinyu Yang, Wenxi He, Chengliang Zhang & Dong Liu. (2023) Calculus Bovis Sativus alleviates estrogen cholestasis-induced gut and liver injury in rats by regulating inflammation, oxidative stress, apoptosis, and bile acid profiles. Journal of Ethnopharmacology 302, pages 115854.
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Eyal Yehezkel, Inbal Israel, Inbal Houri, Moshe Leshno, Oren Shibolet & Ehud Zigmond. (2021) Real-World Management of Patients with Primary Biliary Cholangitis—A Retrospective Study from a Tertiary Medical Center in Israel. Journal of Clinical Medicine 10:19, pages 4551.
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Alessio Gerussi, Umberto Restelli, Davide Croce, Marzia Bonfanti, Pietro Invernizzi & Marco Carbone. (2021) Cost of illness of Primary Biliary Cholangitis - a population-based study. Digestive and Liver Disease 53:9, pages 1167-1170.
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Julián David Martínez-Marín, Sandra Consuelo Henao-Riveros & Martín Alonso Garzón-Olarte. (2021) Hepatopatías autoinmunes. Hallazgos clínicos y de laboratorio en pacientes de un hospital de referencia nacional. Hepatología, pages 355-371.
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Daphne D’Amato, Antonio De Vincentis, Federica Malinverno, Mauro Viganò, Domenico Alvaro, Maurizio Pompili, Antonino Picciotto, Valeria Pace Palitti, Maurizio Russello, Silvia Storato, Marie Graciella Pigozzi, Vincenza Calvaruso, Elisabetta De Gasperi, Ana Lleo, Antonino Castellaneta, Adriano Pellicelli, Nora Cazzagon, Annarosa Floreani, Luigi Muratori, Stefano Fagiuoli, Grazia Anna Niro, Valentina Feletti, Raffaele Cozzolongo, Natalia Terreni, Marco Marzioni, Rinaldo Pellicano, Pietro Pozzoni, Leonardo Baiocchi, Luchino Chessa, Floriano Rosina, Gaetano Bertino, Maria Vinci, Anna Morgando, Ester Vanni, Gaetano Scifo, Rodolfo Sacco, Maria D’Antò, Valentina Bellia, Roberto Boldizzoni, Silvia Casella, Barbara Omazzi, Guido Poggi, Laura Cristoferi, Alessio Gerussi, Vincenzo Ronca, Rosanna Venere, Francesca Ponziani, Maria Cannavò, Alessandro Mussetto, Rosanna Fontana, Francesco Losito, Evelise Frazzetto, Marco Distefano, Francesca Colapietro, Sara Labanca, Giulia Marconi, Giuseppe Grassi, Giovanni Galati, Sarah Elizabeth O’Donnell, Clara Mancuso, Giacomo Mulinacci, Andrea Palermo, Ernesto Claar, Antonio Izzi, Antonio Picardi, Pietro Invernizzi, Marco Carbone & Umberto Vespasiani-Gentilucci. (2021) Real-world experience with obeticholic acid in patients with primary biliary cholangitis. JHEP Reports 3:2, pages 100248.
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Dong Xiang, Yanan Liu, Yue Zu, Jinyu Yang, Wenxi He, Chengliang Zhang & Dong Liu. (2022) Calculus Bovis Sativus  Alleviates Estrogen Cholestasis-Induced Gut and Liver Injury in Rats by Regulating Inflammation, Oxidative Stress, Apoptosis, And Bile Acid Profiles. SSRN Electronic Journal.
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