42
Views
35
CrossRef citations to date
0
Altmetric
Research Article

Sphingomyelin Hydrolysis in the Gut and Clinical Implications in Colorectal Tumorigenesis and Other Gastrointestinal Diseases

Pages 673-683 | Published online: 08 Jul 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

Xiaoxu Wang, Yuming Wang, Jie Xu & Changhu Xue. (2021) Sphingolipids in food and their critical roles in human health. Critical Reviews in Food Science and Nutrition 61:3, pages 462-491.
Read now
J. Bruce German & CoraJ. Dillard. (2006) Composition, Structure and Absorption of Milk Lipids: A Source of Energy, Fat-Soluble Nutrients and Bioactive Molecules. Critical Reviews in Food Science and Nutrition 46:1, pages 57-92.
Read now
Y. Cheng, H.-D. Tauschel, Å. Nilsson, R.-D. Duan. (1999) Ursodeoxycholic Acid Increases the Activities of Alkaline Sphingomyelinase and Caspase-3 in the Rat Colon. Scandinavian Journal of Gastroenterology 34:9, pages 915-920.
Read now

Articles from other publishers (32)

Yin Zhang, Heru Zhao, Bin Liu, Haiyang Shu, Lulu Zhang, Mei Bao, Wenjun Yi, Yong Tan, Xinyu Ji, Chi Zhang, Ning Zhao, Guoming Pang, Dan He, Yuexi Wang, Li Li, Jianfeng Yi & Cheng Lu. (2021) Human serum metabolomic analysis reveals progression for high blood pressure in type 2 diabetes mellitus. BMJ Open Diabetes Research & Care 9:1, pages e002337.
Crossref
Åke Nilsson & Rui-Dong Duan. (2019) Pancreatic and mucosal enzymes in choline phospholipid digestion. American Journal of Physiology-Gastrointestinal and Liver Physiology 316:4, pages G425-G445.
Crossref
Krzysztof Kurek, Bartłomiej Łukaszuk, Dominika M. Piotrowska, Patrycja Wiesiołek, Anna Małgorzata Chabowska & Małgorzata Żendzian-Piotrowska. (2013) Metabolism, Physiological Role, and Clinical Implications of Sphingolipids in Gastrointestinal Tract. BioMed Research International 2013, pages 1-10.
Crossref
ANNA M KUCHTA, PHILIP M KELLY, CATHERINE STANTON & ROSALEEN A DEVERY. (2012) Milk fat globule membrane – a source of polar lipids for colon health? A review. International Journal of Dairy Technology 65:3, pages 315-333.
Crossref
Shiomi Watanabe, Tomoki Takahashi, Leo Tanaka, Yuko Haruta, Makoto Shiota, Masashi Hosokawa & Kazuo Miyashita. (2011) The effect of milk polar lipids separated from butter serum on the lipid levels in the liver and the plasma of obese-model mouse (KK-A ). Journal of Functional Foods 3:4, pages 313-320.
Crossref
Peter R Holt. (2008) New insights into calcium, dairy and colon cancer. World Journal of Gastroenterology 14:28, pages 4429.
Crossref
E.L.F. Graves, A.D. Beaulieu & J.K. Drackley. (2007) Factors Affecting the Concentration of Sphingomyelin in Bovine Milk. Journal of Dairy Science 90:2, pages 706-715.
Crossref
E. V. Dyatlovitskaya & A. G. Kandyba. (2006) Sphingolipids in tumor metastases and angiogenesis. Biochemistry (Moscow) 71:4, pages 347-353.
Crossref
R. Lakshminarayana, M. Raju, T. P. Krishnakantha & V. Baskaran. (2006) Enhanced lutein bioavailability by lyso-phosphatidylcholine in rats. Molecular and Cellular Biochemistry 281:1-2, pages 103-110.
Crossref
R. E. Ward, J. B. German & M. Corredig. 2006. Advanced Dairy Chemistry Volume 2 Lipids. Advanced Dairy Chemistry Volume 2 Lipids 213 244 .
P. W. Parodi. 2006. Advanced Dairy Chemistry Volume 2 Lipids. Advanced Dairy Chemistry Volume 2 Lipids 601 639 .
Jun Wu, Yajun Cheng, Bo A.G. Jönsson, Åke Nilsson & Rui-Dong Duan. (2005) Acid sphingomyelinase is induced by butyrate but does not initiate the anticancer effect of butyrate in HT29 and HepG2 cells. Journal of Lipid Research 46:9, pages 1944-1952.
Crossref
Luisa Di Marzio, Alfredo Di Leo, Benedetta Cinque, Donatella Fanini, Alessio Agnifili, Pasquale Berloco, Michele Linsalata, Dionigi Lorusso, Michele Barone, Claudio De Simone & Maria Grazia Cifone. (2005) Detection of Alkaline Sphingomyelinase Activity in Human Stool: Proposed Role as a New Diagnostic and Prognostic Marker of Colorectal Cancer. Cancer Epidemiology, Biomarkers & Prevention 14:4, pages 856-862.
Crossref
Jun WU, Gert H. HANSEN, Åke NILSSON & Rui-Dong DUAN. (2005) Functional studies of human intestinal alkaline sphingomyelinase by deglycosylation and mutagenesis. Biochemical Journal 386:1, pages 153-160.
Crossref
Jun Wu, Yajun Cheng, Carina Palmberg, Tomas Bergman, Åke Nilsson & Rui-Dong Duan. (2005) Cloning of alkaline sphingomyelinase from rat intestinal mucosa and adjusting of the hypothetical protein XP_221184 in GenBank. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1687:1-3, pages 94-102.
Crossref
Jun Wu, Fuli Liu, Åke Nilsson & Rui-Dong Duan. (2004) Pancreatic trypsin cleaves intestinal alkaline sphingomyelinase from mucosa and enhances the sphingomyelinase activity. American Journal of Physiology-Gastrointestinal and Liver Physiology 287:5, pages G967-G973.
Crossref
Sang K. Noh & Sung I. Koo. (2004) Milk Sphingomyelin Is More Effective than Egg Sphingomyelin in Inhibiting Intestinal Absorption of Cholesterol and Fat in Rats. The Journal of Nutrition 134:10, pages 2611-2616.
Crossref
Sang K. Noh & Sung I. Koo. (2003) Egg Sphingomyelin Lowers the Lymphatic Absorption of Cholesterol and α-Tocopherol in Rats. The Journal of Nutrition 133:11, pages 3571-3576.
Crossref
Rui-Dong Duan, Tomas Bergman, Ning Xu, Jun Wu, Yajun Cheng, Jianxin Duan, Sven Nelander, Carina Palmberg & Åke Nilsson. (2003) Identification of Human Intestinal Alkaline Sphingomyelinase as a Novel Ecto-enzyme Related to the Nucleotide Phosphodiesterase Family. Journal of Biological Chemistry 278:40, pages 38528-38536.
Crossref
Rui-Dong Duan, Yajun Cheng, Gert Hansen, Erik Hertervig, Jian-Jun Liu, Ingvar Syk, Hans Sjo¨stro¨m & Åke Nilsson. (2003) Purification, localization, and expression of human intestinal alkaline sphingomyelinase. Journal of Lipid Research 44:6, pages 1241-1250.
Crossref
Liping Yang, Marja Mutanen, Yajun Cheng & Rui-Dong Duan. (2002) Effects of red meat and fiber in high fat diet on activities of sphingomyelinase, ceramidase and caspase-3 in rat colonic mucosa. The Journal of Nutritional Biochemistry 13:8, pages 499-504.
Crossref
Jian-Jun Liu, Åke Nilsson & Rui-Dong Duan. (2002) In vitro effects of fat, FA, and cholesterol on sphingomyelin hydrolysis induced by rat intestinal alkaline sphingomyelinase. Lipids 37:5, pages 469-474.
Crossref
Yajun Cheng, Åke Nilsson, Elisabeth Tömquist & Rui-Dong Duan. (2002) Purification, characterization, and expression of rat intestinal alkaline sphingomyelinase. Journal of Lipid Research 43:2, pages 316-324.
Crossref
Liping Yang, Marja Mutanen, Yajun Cheng & Rui-Dong Duan. (2002) Effects of Fat, Beef and Fiber in Diets on Activities of Sphingomyelinase, Ceramidase and Caspase-3 in Rat Colonic Mucosa. Medical Principles and Practice 11:3, pages 150-156.
Crossref
Lars I. Hellgren. (2001) Occurrence of bioactive sphingolipids in meat and fish products. European Journal of Lipid Science and Technology 103:10, pages 661-667.
Crossref
Rui-Dong Duan, Yajun Cheng, Liping Yang, Lena Ohlsson & Åke Nilsson. (2001) Evidence for specific ceramidase present in the intestinal contents of rats and humans. Lipids 36:8, pages 807-812.
Crossref
Graeme H. McIntosh & Richard K. Le Leu. (2001) The influence of dietary proteins on colon cancer risk. Nutrition Research 21:7, pages 1053-1066.
Crossref
Katharine E Carr. 2001. 1 119 .
Jian-Jun Liu, Åke Nilsson & Rui-Dong Duan. (2000) Effects of phospholipids on sphingomyelin hydrolysis induced by intestinal alkaline sphingomyelinase: an in vitro study. The Journal of Nutritional Biochemistry 11:4, pages 192-197.
Crossref
Rui-Dong Duan & åke Nilsson. 2000. Sphingolipid Metabolism and Cell Signaling Part A. Sphingolipid Metabolism and Cell Signaling Part A 276 286 .
Åke Nilsson & Rui-Dong Duan. (1999) Alkaline sphingomyelinases and ceramidases of the gastrointestinal tract. Chemistry and Physics of Lipids 102:1-2, pages 97-105.
Crossref
Martin LipkinBandaru ReddyHarold NewmarkSergio A. Lamprecht. (1999) DIETARY FACTORS IN HUMAN COLORECTAL CANCER. Annual Review of Nutrition 19:1, pages 545-586.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.