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Research Article

Fructose-Sorbitol Malabsorption and Symptom Provocation in Irritable Bowel Syndrome: Relationship to Enteric Hypersensitivity and Dysmotility

Pages 1158-1163 | Published online: 08 Jul 2009

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M. Ledochowski, B. Widner, C. Murr, B. Sperner-Unterweger, D. Fuchs. (2001) Fructose Malabsorption is Associated with Decreased Plasma Tryptophan. Scandinavian Journal of Gastroenterology 36:4, pages 367-371.
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Karen Van den Houte, E. Colomier, Karen Routhiaux, Z. Mariën, J. Schol, J. Van den Bergh, J. Vanderstappen, N. Pauwels, A. Joos, J. Arts, Ph. Caenepeel, F. De Clerck, Christophe Matthys, A. Meulemans, M. Jones, Tim Vanuytsel, F. Carbone & Jan Tack. (2024) Efficacy and Findings of a Blinded Randomized Reintroduction Phase for the Low FODMAP Diet in Irritable Bowel Syndrome. Gastroenterology.
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Luisa Bertin, Miriana Zanconato, Martina Crepaldi, Giovanni Marasco, Cesare Cremon, Giovanni Barbara, Brigida Barberio, Fabiana Zingone & Edoardo Vincenzo Savarino. (2024) The Role of the FODMAP Diet in IBS. Nutrients 16:3, pages 370.
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Sai Suseel Sarvepalli, Shree Laya Vemula, Saikumar Aramadaka, Raam Mannam, Rajagopal Sankara Narayanan, Arpit Bansal & Vishnu R Yanamaladoddi. (2023) Digesting the Impact of Diet on Irritable Bowel Syndrome (IBS): Exploring Solutions for Controlling IBS. Cureus.
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Rosa Leonôra Salerno SOARES. (2018) IRRITABLE BOWEL SYNDROME, FOOD INTOLERANCE AND NON- CELIAC GLUTEN SENSITIVITY. A NEW CLINICAL CHALLENGE. Arquivos de Gastroenterologia 55:4, pages 417-422.
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Jelena Vulevic, George Tzortzis, Aleksandra Juric & Glenn R. Gibson. (2018) Effect of a prebiotic galactooligosaccharide mixture (B‐GOS®) on gastrointestinal symptoms in adults selected from a general population who suffer with bloating, abdominal pain, or flatulence. Neurogastroenterology & Motility 30:11.
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Bin-Rui Chen, Li-Jun Du, Hui-Qin He, John J Kim, Yan Zhao, Ya-Wen Zhang, Liang Luo & Ning Dai. (2017) Fructo-oligosaccharide intensifies visceral hypersensitivity and intestinal inflammation in a stress-induced irritable bowel syndrome mouse model. World Journal of Gastroenterology 23:47, pages 8321-8333.
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Caitlin Batt, Niamh Fanning, Jill Drake, Christopher Frampton, Richard B. Gearry & Lisa K. Stamp. (2017) Fructose malabsorption in people with and without gout: A case–control study. Seminars in Arthritis and Rheumatism 47:2, pages 257-263.
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Heidi M Staudacher & Kevin Whelan. (2017) The low FODMAP diet: recent advances in understanding its mechanisms and efficacy in IBS. Gut 66:8, pages 1517-1527.
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Adrienne Lenhart & William D Chey. (2017) A Systematic Review of the Effects of Polyols on Gastrointestinal Health and Irritable Bowel Syndrome. Advances in Nutrition 8:4, pages 587-596.
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Marie C. M. HalliezJean-Paul MottaTroy D. FeenerGaetan GuérinLaetitia LeGoffArnaud François, Elodie Colasse, Loic FavennecGilles GargalaTamia K. Lapointe, Christophe Altier & André G. Buret. (2016) Giardia duodenalis induces paracellular bacterial translocation and causes postinfectious visceral hypersensitivity . American Journal of Physiology-Gastrointestinal and Liver Physiology 310:8, pages G574-G585.
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Pasquale Mansueto, Aurelio Seidita, Alberto D'Alcamo & Antonio Carroccio. (2015) Role of FODMAPs in Patients With Irritable Bowel Syndrome. Nutrition in Clinical Practice 30:5, pages 665-682.
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M. C. E. Lomer. (2014) Review article: the aetiology, diagnosis, mechanisms and clinical evidence for food intolerance. Alimentary Pharmacology & Therapeutics 41:3, pages 262-275.
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Heidi M. Staudacher, Peter M. Irving, Miranda C. E. Lomer & Kevin Whelan. (2014) Mechanisms and efficacy of dietary FODMAP restriction in IBS. Nature Reviews Gastroenterology & Hepatology 11:4, pages 256-266.
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P. Komericki, M. Akkilic‐Materna, T. Strimitzer, K. Weyermair, H. F. Hammer & W. Aberer. (2012) Oral xylose isomerase decreases breath hydrogen excretion and improves gastrointestinal symptoms in fructose malabsorption – a double‐blind, placebo‐controlled study. Alimentary Pharmacology & Therapeutics 36:10, pages 980-987.
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Heinz F. Hammer & Johann Hammer. (2012) Diarrhea Caused By Carbohydrate Malabsorption. Gastroenterology Clinics of North America 41:3, pages 611-627.
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Jacqueline S. Barrett & Peter R. Gibson. (2012) Fermentable oligosaccharides, disaccharides, monosaccharides and polyols (FODMAPs) and nonallergic food intolerance: FODMAPs or food chemicals?. Therapeutic Advances in Gastroenterology 5:4, pages 261-268.
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Eduard Cabré. (2011) Clinical Nutrition University: Nutrition in the prevention and management of irritable bowel syndrome, constipation and diverticulosis. e-SPEN, the European e-Journal of Clinical Nutrition and Metabolism 6:2, pages e85-e95.
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Eduard Cabré. (2010) Irritable bowel syndrome: can nutrient manipulation help?. Current Opinion in Clinical Nutrition and Metabolic Care 13:5, pages 581-587.
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J. S. BARRETT, R. B. GEARRY, J. G. MUIR, P. M. IRVING, R. ROSE, O. ROSELLA, M. L. HAINES, S. J. SHEPHERD & P. R. GIBSON. (2010) Dietary poorly absorbed, short‐chain carbohydrates increase delivery of water and fermentable substrates to the proximal colon. Alimentary Pharmacology & Therapeutics 31:8, pages 874-882.
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Christoph Högenauer & Heinz F. Hammer. 2010. Sleisenger and Fordtran's Gastrointestinal and Liver Disease. Sleisenger and Fordtran's Gastrointestinal and Liver Disease 1735 1767.e7 .
J. S. BARRETT, P. M. IRVING, S. J. SHEPHERD, J. G. MUIR & P. R. GIBSON. (2009) Comparison of the prevalence of fructose and lactose malabsorption across chronic intestinal disorders. Alimentary Pharmacology & Therapeutics 30:2, pages 165-174.
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William D. Heizer, Susannah Southern & Susan McGovern. (2009) The Role of Diet in Symptoms of Irritable Bowel Syndrome in Adults: A Narrative Review. Journal of the American Dietetic Association 109:7, pages 1204-1214.
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S. M. Skoog, A. E. Bharucha & A. R. Zinsmeister. (2008) Comparison of breath testing with fructose and high fructose corn syrups in health and IBS. Neurogastroenterology & Motility 20:5, pages 505-511.
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Nirmal S. Mann & Eddie C. Cheung. (2008) Fructose-induced Breath Hydrogen in Patients With Fruit Intolerance. Journal of Clinical Gastroenterology 42:2, pages 157-159.
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Jan L. Madsen, Jan Linnet & Jüri J. Rumessen. (2006) Effect of Nonabsorbed Amounts of a Fructose–Sorbitol Mixture on Small Intestinal Transit in Healthy Volunteers. Digestive Diseases and Sciences 51:1, pages 147-153.
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Peter L. Beyer, Elena M. Caviar & Richard W. McCallum. (2005) Fructose Intake at Current Levels in the United States May Cause Gastrointestinal Distress in Normal Adults. Journal of the American Dietetic Association 105:10, pages 1559-1566.
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Suzanne M. Skoog & Adil E. Bharucha. (2004) Dietary Fructose and Gastrointestinal Symptoms: A Review. The American Journal of Gastroenterology 99:10, pages 2046-2050.
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Tony J. Lembo & Rebecca N. Fink. (2002) Clinical Assessment of Irritable Bowel Syndrome. Journal of Clinical Gastroenterology 35:Supplement, pages S31-S36.
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D.Cyril D’Souza, Robert M Berman, John H Krystal & Dennis S Charney. (1999) Symptom provocation studies in psychiatric disorders: scientific value, risks, and future. Biological Psychiatry 46:8, pages 1060-1080.
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