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Research Article

Effect of Substance P on Histamine Secretion from Gut Mucosa in Inflammatory Bowel Disease

Pages 496-503 | Published online: 08 Jul 2009

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Marcello Fiorani, Livio Enrico Del Vecchio, Pasquale Dargenio, Francesco Kaitsas, Tommaso Rozera, Serena Porcari, Antonio Gasbarrini, Giovanni Cammarota & Gianluca Ianiro. (2023) Histamine-producing bacteria and their role in gastrointestinal disorders. Expert Review of Gastroenterology & Hepatology 17:7, pages 709-718.
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Jörg R. Aschenbach, Frank Ahrens, Hubert G. Schwelberger, Brigitta Fürll, Uwe Roesler, Andreas Hensel & Gotthold Gäbel. (2007) Functional characteristics of the porcine colonic epithelium following transportation stress and Salmonella infection. Scandinavian Journal of Gastroenterology 42:6, pages 708-716.
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C. G. B. Peterson, P. Sangfelt, M. Wagner, T. Hansson, H. Lettesjö & M. Carlson. (2007) Fecal levels of leukocyte markers reflect disease activity in patients with ulcerative colitis. Scandinavian Journal of Clinical and Laboratory Investigation 67:8, pages 810-820.
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M.-A. Denis, R. Louis, M. Malaise, J. Belaiche, E. Louis. (2001) Increased Response of Blood Eosinophils to Various Chemotactic Agents in Quiescent Crohn Disease. Scandinavian Journal of Gastroenterology 36:2, pages 190-195.
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M. Raithel, S. Winterkamp, A. Pacurar, P. Ulrich, J. Hochberger, E. G. Hahn. (2001) Release of Mast Cell Tryptase from Human Colorectal Mucosa in Inflammatory Bowel Disease. Scandinavian Journal of Gastroenterology 36:2, pages 174-179.
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Dan-Yang Wang, Shinobu Ohnuma, Hideyuki Suzuki, Masaharu Ishida, Kentaro Ishii, Takashi Hirosawa, Tomoaki Hirashima, Megumi Murakami, Minoru Kobayashi, Katsuyoshi Kudoh, Sho Haneda, Hiroaki Musha, Takeshi Naitoh & Michiaki Unno. (2023) Infliximab Inhibits Colitis Associated Cancer in Model Mice by Downregulating Genes Associated with Mast Cells and Decreasing Their Accumulation. Current Issues in Molecular Biology 45:4, pages 2895-2907.
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Patrick Hawker, Li Zhang & Lu Liu. (2023) Mas‐Related G Protein‐Coupled Receptors in Gastrointestinal Dysfunction and Inflammatory Bowel Disease: A Review.. British Journal of Pharmacology.
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M Motiur Rahman, Sheuli Afroz, Subha Arthur & Uma Sundaram. (2021) Mast Cell Mediated Regulation of Small Intestinal Chloride Malabsorption in SAMP1/YitFc Mouse Model of Spontaneous Chronic Ileitis. Cells 10:3, pages 697.
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Andrzej Rychlik, Slawomir Gonkowski, Krystyna Makowska, Ewa Kaczmar & Jaroslaw Calka. (2020) Changes in the expression of substance P in nerve fibres of the colonic mucosa in dogs suffering from inflammatory bowel disease. Acta Veterinaria Hungarica 68:2, pages 154-159.
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Michael Stassen, Ann-Kathrin Hartmann, Sharon Jiménez Delgado, Susann Dehmel & Armin Braun. (2019) Mast cells within cellular networks. Journal of Allergy and Clinical Immunology 144:4, pages S46-S54.
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Mercé Albert-Bayo, Irene Paracuellos, Ana M. González-Castro, Amanda Rodríguez-Urrutia, María J. Rodríguez-Lagunas, Carmen Alonso-Cotoner, Javier Santos & María Vicario. (2019) Intestinal Mucosal Mast Cells: Key Modulators of Barrier Function and Homeostasis. Cells 8:2, pages 135.
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E. M. Lennon, L. B. Borst, L. L. Edwards & A. J. Moeser. (2018) Mast Cells Exert Anti-Inflammatory Effects in an IL10 −/− Model of Spontaneous Colitis . Mediators of Inflammation 2018, pages 1-13.
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Y. Aydemir, A. Pınar, G. Hızal, H. Demir, İ. N. Saltık Temizel, H. Özen, F. Akbıyık & A. Yüce. (2016) Neutrophil volume distribution width as a new marker in detecting inflammatory bowel disease activation. International Journal of Laboratory Hematology 39:1, pages 51-57.
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William Adams, Lisa Mitchell, Roberto Candelaria-Santiago, Jody Hefner & Joseph Gramling. (2016) Concurrent Ulcerative Colitis and Neurofibromatosis Type 1: The Question of a Common Pathway. Pediatrics 137:2.
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Guy Boeckxstaens. (2015) Mast cells and inflammatory bowel disease. Current Opinion in Pharmacology 25, pages 45-49.
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P. S. Satheeshkumar & Minu P. Mohan. (2014) Tachykinin Peptide, Substance P, and Its Receptor NK-1R Play an Important Role in Alimentary Tract Mucosal Inflammation During Cytotoxic Therapy. Digestive Diseases and Sciences 59:12, pages 2864-2873.
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Felicita Baratelli, Mary Le, George B. Gershman & Samuel W. French. (2014) Do mast cells play a pathogenetic role in neurofibromatosis type 1 and ulcerative colitis?. Experimental and Molecular Pathology 96:2, pages 230-234.
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S. Smolinska, M. Jutel, R. Crameri & L. O'Mahony. (2014) Histamine and gut mucosal immune regulation. Allergy 69:3, pages 273-281.
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Marina García-Miguel, M. Julieta González, Rodrigo Quera & Marcela A. Hermoso. (2013) Innate Immunity Modulation by the IL-33/ST2 System in Intestinal Mucosa. BioMed Research International 2013, pages 1-13.
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Elizabeth L. Overman, Jean E. Rivier & Adam J. Moeser. (2012) CRF Induces Intestinal Epithelial Barrier Injury via the Release of Mast Cell Proteases and TNF-α. PLoS ONE 7:6, pages e39935.
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Sabine Buhner & Michael Schemann. (2012) Mast cell–nerve axis with a focus on the human gut. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1822:1, pages 85-92.
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å. v. Keita, J. D. Söderholm & A.-c. Ericson. (2010) Stress-induced barrier disruption of rat follicle-associated epithelium involves corticotropin-releasing hormone, acetylcholine, substance P, and mast cells. Neurogastroenterology & Motility 22:7, pages 770-e222.
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Katherine A Radek. (2010) Antimicrobial anxiety: the impact of stress on antimicrobial immunity. Journal of Leukocyte Biology 88:2, pages 263-277.
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Laura Y. Gorczynski & Reginald M. Gorczynski. 2010. The Brain and Host Defense. The Brain and Host Defense 131 144 .
Joel E. Mawdsley, David G. Jenkins, Marion G. Macey, Louise Langmead & David S. Rampton. (2008) The Effect of Hypnosis on Systemic and Rectal Mucosal Measures of Inflammation in Ulcerative Colitis. The American Journal of Gastroenterology 103:6, pages 1460-1469.
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H. U. DE SCHEPPER, J. G. DE MAN, T. G. MOREELS, P. A. PELCKMANS & B. Y. DE WINTER. (2008) Review article: gastrointestinal sensory and motor disturbances in inflammatory bowel disease – clinical relevance and pathophysiological mechanisms. Alimentary Pharmacology & Therapeutics 27:8, pages 621-637.
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Ashkan Farhadi, Ali Keshavarzian, Jeremy Z Fields, Shriram Jakate, Maliha Shaikh & Ali Banan. (2007) Reduced immunostaining for c‐kit receptors in mucosal mast cells in inflammatory bowel disease. Journal of Gastroenterology and Hepatology 22:12, pages 2338-2343.
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M. Raithel, S. Winterkamp, M. Weidenhiller, S. Müller & E. G. Hahn. (2006) Combination therapy using fexofenadine, disodium cromoglycate, and a hypoallergenic amino acid-based formula induced remission in a patient with steroid-dependent, chronically active ulcerative colitis. International Journal of Colorectal Disease 22:7, pages 833-839.
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C.B. Collins, J. McGrath, A.W. Baird & D.P. Campion. (2007) Effect of Mast Cell Degranulation on Chicken Ileal Ion Transport In Vitro. Poultry Science 86:5, pages 843-849.
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Christoph W. Michalski, Frank Autschbach, Federico Selvaggi, Xin Shi, Fabio Francesco Di Mola, Antoine Roggo, Michael W. Müller, Pierluigi Di Sebastiano, Markus W. Büchler, Thomas Giese & Helmut Friess. (2007) Increase in substance P precursor mRNA in noninflamed small-bowel sections in patients with Crohn’s disease. The American Journal of Surgery 193:4, pages 476-481.
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HON WAI KOON & CHARALABOS POTHOULAKIS. (2006) Immunomodulatory Properties of Substance P. Annals of the New York Academy of Sciences 1088:1, pages 23-40.
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Anneke Rijnierse, Kim M.F. van Zijl, Andries S. Koster, Frans P. Nijkamp & Aletta D. Kraneveld. (2006) Beneficial effect of tachykinin NK1 receptor antagonism in the development of hapten-induced colitis in mice. European Journal of Pharmacology 548:1-3, pages 150-157.
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Joel E. Mawdsley, Marion G. Macey, Roger M. Feakins, Louise Langmead & David S. Rampton. (2006) The Effect of Acute Psychologic Stress on Systemic and Rectal Mucosal Measures of Inflammation in Ulcerative Colitis. Gastroenterology 131:2, pages 410-419.
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Giovanni Barbara, Vincenzo Stanghellini, Roberto De Giorgio, Cesare Cremon, Graeme S. Cottrell, Donatella Santini, Gianandrea Pasquinelli, Antonio M. Morselli-Labate, Eileen F. Grady, Nigel W. Bunnett, Stephen M. Collins & Roberto Corinaldesi. (2004) Activated mast cells in proximity to colonic nerves correlate with abdominal pain in irritable bowel syndrome. Gastroenterology 126:3, pages 693-702.
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Zhao Shen LI, Wen Zhu DONG, Duo Wu ZOU, Xiao Ping ZOU, Guo Ming XU, Ai Yong ZHU, Ning YIN, Yan Fang GONG, Zhen Xing SUN, Can XU & Xiao Hua MAN. (2003) Mast cells and neuropeptidergic terminals: Experimental studies of the mechanism of visceral hypersensitivity in irritable bowel syndrome. Chinese Journal of Digestive Diseases 4:3, pages 111-117.
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