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Original Article

Impact of switching antiretroviral therapy on lipodystrophy and other metabolic complications: a review

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Pages 244-253 | Received 02 Dec 2003, Accepted 30 Jan 2004, Published online: 08 Jul 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (2)

Anthony S. Wierzbicki, Scott D. Purdon, Timothy C. Hardman, Ranjababu Kulasegaram & Barry S. Peters. (2008) HIV lipodystrophy and its metabolic consequences: implications for clinical practice. Current Medical Research and Opinion 24:3, pages 609-624.
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Steen B Haugaard. (2006) Toxic metabolic syndrome associated with HAART. Expert Opinion on Drug Metabolism & Toxicology 2:3, pages 429-445.
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Articles from other publishers (21)

E. L. Sorkina, V. V. Chichkova, I. A. Sklyanik, M. V. Shestakova, G. A. Mel'nichenko & A. Barkan. (2021) The role of glucose and insulin in the metabolic regulation of growth hormone secretion. Problems of Endocrinology 67:1, pages 52-59.
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Amy Y.‐Y. Chen & Amit Garg. 2016. Rook's Textbook of Dermatology, Ninth Edition. Rook's Textbook of Dermatology, Ninth Edition 1 36 .
Josephine Pui-Hing Wong, Alan Tai-Wai Li, Maurice Kwong-Lai Poon & Kenneth Po-Lun Fung. (2013) An exploratory study on the mental health of immigrants, refugees and non-status people living with HIV in Toronto. International Journal of Migration, Health and Social Care 9:3, pages 122-134.
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Esteban Martínez. (2011) Disorders of fat partitioning in treated HIV–infection. Best Practice & Research Clinical Endocrinology & Metabolism 25:3, pages 415-427.
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Siddharth H Sheth & Robin J Larson. (2010) The efficacy and safety of insulin-sensitizing drugs in HIV-associated lipodystrophy syndrome: a meta-analysis of randomized trials. BMC Infectious Diseases 10:1.
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Carl Grunfeld, Michael Saag, Joseph Cofrancesco, Cora Elizabeth Lewis, Richard Kronmal, Steven Heymsfield, Phyllis C Tien, Peter Bacchetti, Michael Shlipak & Rebecca Scherzer. (2010) Regional adipose tissue measured by MRI over 5 years in HIV-infected and control participants indicates persistence of HIV-associated lipoatrophy. AIDS 24:11, pages 1717-1726.
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BR Hansen, J Petersen, SB Haugaard, S Madsbad, N Obel, Y Suzuki & O Andersen. (2009) The prevalence of metabolic syndrome in Danish patients with HIV infection: the effect of antiretroviral therapy. HIV Medicine 10:6, pages 378-387.
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Jussi Sutinen. (2009) The Effects of Thiazolidinediones on Metabolic Complications and Lipodystrophy in HIV-Infected Patients. PPAR Research 2009, pages 1-15.
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Joseph CofrancescoJr.Jr., Eric FreedlandGrace McComsey. (2009) Treatment Options for HIV-Associated Central Fat Accumulation. AIDS Patient Care and STDs 23:1, pages 5-18.
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Raphael J. Landovitz, Jonathan B. Angel, Christian Hoffmann, Heinz Horst, Milos Opravil, Jianmin Long, Wayne Greaves & Gerd Fätkenheuer. (2008) Phase II Study of Vicriviroc versus Efavirenz (both with Zidovudine/Lamivudine) in Treatment‐Naive Subjects with HIV‐1 Infection. The Journal of Infectious Diseases 198:8, pages 1113-1122.
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R. A. Bradbury & K. Samaras. (2008) Antiretroviral therapy and the human immunodeficiency virus – improved survival but at what cost?. Diabetes, Obesity and Metabolism 10:6, pages 441-450.
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Rebeca Goiriz & Jesús Fernández Herrera. (2008) Toxicodermias en pacientes con síndrome de inmunodeficiencia adquirida. Piel 23:6, pages 303-308.
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W. Todd Cade. (2008) Left Ventricular Dysfunction in Human Immunodeficiency Virus Infection. Journal of the CardioMetabolic Syndrome 3:2, pages 83-87.
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Julian Falutz. (2007) Therapy Insight: body-shape changes and metabolic complications associated with HIV and highly active antiretroviral therapy. Nature Clinical Practice Endocrinology & Metabolism 3:9, pages 651-661.
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Etai Funk, Anthony E. Brissett, Craig D. Friedman & Fred J. Bressler. (2009) HIV‐Associated Facial Lipoatrophy: Establishment of a Validated Grading Scale. The Laryngoscope 117:8, pages 1349-1353.
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Emma Hammond & David Nolan. (2007) Adipose tissue inflammation and altered adipokine and cytokine production in antiretroviral therapy-associated lipodystrophy. Current Opinion in HIV and AIDS 2:4, pages 274-281.
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J. Ockenga, R. Grimble, C. Jonkers-Schuitema, D. Macallan, J.-C. Melchior, H.P. Sauerwein, A. Schwenk & U. Süttmann. (2006) ESPEN Guidelines on Enteral Nutrition: Wasting in HIV and other chronic infectious diseases. Clinical Nutrition 25:2, pages 319-329.
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Lisa A Kosmiski, Heidi L Miller & Dwight J Klemm. (2005) In Combination, Nucleoside Reverse Transcriptase Inhibitors Have Significant Effects on 3T3–L1 Adipocyte Lipid Accumulation and Survival. Antiviral Therapy 11:2, pages 187-196.
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Alessandra Viganò, Grace M Aldrovandi, Vania Giacomet, Marzia Merlo, Laura Martelli, Silvia Beretta, Paola Luraschi, Giuseppe Rombolà & Stefano Mora. (2005) Improvement in Dyslipidaemia after Switching Stavudine to Tenofovir and Replacing Protease Inhibitors with Efavirenz in HIV-Infected Children. Antiviral Therapy 10:8, pages 917-924.
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Jussi Sutinen. (2005) Interventions for managing antiretroviral therapy-associated lipoatrophy. Current Opinion in Infectious Diseases 18:1, pages 25-33.
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Dan Streja. (2004) Metabolic syndrome and other factors associated with increased risk of diabetes. Clinical Cornerstone 6:3, pages S14-S29.
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