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ORIGINAL ARTICLE

Neutrophil CD64 (FcγRI) expression is a specific marker of bacterial infection: A study on the kinetics and the impact of major surgery

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Pages 525-535 | Received 04 Sep 2006, Published online: 08 Jul 2009

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Tomislav Jukic, Alojz Ihan & David Stubljar. (2015) Dynamics of inflammation biomarkers C-reactive protein, leukocytes, neutrophils, and CD64 on neutrophils before and after major surgical procedures to recognize potential postoperative infection. Scandinavian Journal of Clinical and Laboratory Investigation 75:6, pages 500-507.
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Oskar Eriksson, Lena Douhan Håkansson, Malgorzata Karawajczyk & Daniel Garwicz. (2015) Neutrophil CD64 expression – comparison of two different flow cytometry protocols on EPICs MCL and the Leuko64™ assay on a Celldyn Sapphire haematology analyser. Scandinavian Journal of Clinical and Laboratory Investigation 75:5, pages 428-433.
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Bernard N Jukema, Titus A P de Hond, Martijn Kroon, Anna E Maranus, Leo Koenderman & Karin A H Kaasjager. (2024) Point-of-care neutrophil and monocyte surface markers differentiate bacterial from viral infections at the emergency department within 30 min. Journal of Leukocyte Biology 115:4, pages 714-722.
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Dheeraj R. Yalamanchili, Zachary A. Rockov, Landon S. Polakof, Eytan M. Debbi, Sumire K. Kitahara & Guy D. Paiement. (2023) Serum CD64 as a Marker for Chronic Periprosthetic Joint Infection. Arthroplasty Today 21, pages 101138.
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Krystle L. Ong, Marcus D. Davis, Kalyn K. Purnell, Hannah Cutshall, Harish C. Pal, Ashley N. Connelly, Christian X. Fay, Valeriya Kuznetsova, Elizabeth E. Brown & Zdenek Hel. (2023) Distinct phenotype of neutrophil, monocyte, and eosinophil populations indicates altered myelopoiesis in a subset of patients with multiple myeloma. Frontiers in Oncology 12.
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Lu-Lu Cao, Wei-Wei Wang, Li Zhao, Ji-Ru Li, Xiang-Mei Kong, Yue-Niu Zhu & Xiao-Dong Zhu. (2022) Neutrophil CD64 index for diagnosis of infectious disease in the pediatric ICU: a single-center prospective study. BMC Pediatrics 22:1.
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S. I. Achkasov, M. A. Sukhina, A. I. Moskalev & E. N. Nabiev. (2019) THE ROLE OF BIOLOGICAL MARKERS IN THE DIAGNOSIS OF POSTOPERATIVE INFECTIONS IN COLORECTAL CANCER SURGERY (review). Koloproktologia 18:3(69), pages 105-118.
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M Feng, S L Zhang, Z J Liang, Y L Wang, X C Zhao, C Gao, H Guo & J Luo. (2019) Peripheral neutrophil CD64 index combined with complement, CRP, WBC count and B cells improves the ability of diagnosing bacterial infection in SLE. Lupus 28:3, pages 304-316.
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A. Saleh, J. George, M. Faour, A. K. Klika & C. A. Higuera. (2018) Serum biomarkers in periprosthetic joint infections. Bone & Joint Research 7:1, pages 85-93.
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U. Hassan, T. Ghonge, B. Reddy, M. Patel, M. Rappleye, I. Taneja, A. Tanna, R. Healey, N. Manusry, Z. Price, T. Jensen, J. Berger, A. Hasnain, E. Flaugher, S. Liu, B. Davis, J. Kumar, K. White & R. Bashir. (2017) A point-of-care microfluidic biochip for quantification of CD64 expression from whole blood for sepsis stratification. Nature Communications 8:1.
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Milena Kerin Povsic, Bojana Beovic & Alojz Ihan. (2017) Perioperative increase in neutrophil CD64 expression is an indicator for intra-abdominal infection after colorectal cancer surgery. Radiology and Oncology 51:2, pages 211-220.
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Xiao Wang, Zhong-Yun Li, Ling Zeng, An-Qiang Zhang, Wei Pan, Wei Gu & Jian-Xin Jiang. (2015) Neutrophil CD64 expression as a diagnostic marker for sepsis in adult patients: a meta-analysis. Critical Care 19:1.
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Joris R. Delanghe & Marijn M. Speeckaert. (2015) Translational research and biomarkers in neonatal sepsis. Clinica Chimica Acta 451, pages 46-64.
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Elena Titova, Marthe Wedø Aune, Kristin Fonn, Anne Hildur Henriksen & Arne Åsberg. (2015) Neutrophil CD64 Expression as a Diagnostic Marker in Patients Hospitalized with Exacerbations of COPD: A Prospective Observational Study. Lung 193:5, pages 717-724.
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Per Venge, Lena Douhan-Håkansson, Daniel Garwicz, Christer Peterson, Shengyuan Xu & Karlis Pauksen. (2015) Human Neutrophil Lipocalin as a Superior Diagnostic Means To Distinguish between Acute Bacterial and Viral Infections. Clinical and Vaccine Immunology 22:9, pages 1025-1032.
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J. Jämsä, V. Huotari, E.‐R. Savolainen, H. Syrjälä & T. Ala‐kokko. (2015) Kinetics of leukocyte CD11b and CD64 expression in severe sepsis and non‐infectious critical care patients. Acta Anaesthesiologica Scandinavica 59:7, pages 881-891.
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Linda Wong, Beth L. Hill, Benjamin C. Hunsberger, C. Bruce Bagwell, Adam D. Curtis & Bruce H. Davis. (2015) Automated analysis of flow cytometric data for measuring neutrophil CD64 expression using a multi‐instrument compatible probability state model. Cytometry Part B: Clinical Cytometry 88:4, pages 227-235.
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David Stubljar & Miha Skvarc. (2014) Expression of CD64 on neutrophils can be used to predict the severity of bloodstream infection before broad range 16S rRNA PCR. Folia Microbiologica 60:2, pages 111-118.
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Kok P. M. van Kessel, Jovanka Bestebroer & Jos A. G. van Strijp. (2014) Neutrophil-Mediated Phagocytosis of Staphylococcus aureus. Frontiers in Immunology 5.
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Hao Zhang, Xian-Long Ling, Yu-Yun Wu, Mu-Han Lü, Hong Guo, Peng-Bin Zhang, Xiao-Yan Zhao & Shi-Ming Yang. (2014) CD64 Expression Is Increased in Patients with Severe Acute Pancreatitis: Clinical Significance. Gut and Liver 8:4, pages 445-451.
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James Perry. (2013) The assessment of neutrophil cd64 count as an early warning marker of joint replacement infection. Archives of Orthopaedic and Trauma Surgery 133:10, pages 1351-1358.
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Hristina Andreeva, Steinar Lundemoen, Godfrid Greve, Rune Haaverstad & Gustav Fjaertoft. (2011) Kinetic of monocytes Fcγ receptors in patients after coronary artery bypass. Open Medicine 6:1, pages 31-36.
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Magdalena Kwiatkowska-Gruca, Jakub Behrendt, Anna Pukas, Wojciech Suda, Łukasz Sędłak & Urszula Godula-Stuglik. (2010) Ocena ekspresji molekuł adhezji komórkowej CD11a, CD11b, CD11c, CD13, CD18, CD54 i CD62L na powierzchni granulocytów i monocytów krwi obwodowej u noworodków donoszonych. Pediatria Polska 85:5, pages 446-450.
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Jari Nuutila. (2010) The novel applications of the quantitative analysis of neutrophil cell surface FcγRI (CD64) to the diagnosis of infectious and inflammatory diseases. Current Opinion in Infectious Diseases 23:3, pages 268-274.
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Dilek Dilli, Ş. Suna Ogˇuz, Ugˇur Dilmen, M. Yavuz Köker & Murat Kızılgün. (2010) Predictive values of neutrophil CD64 expression compared with interleukin‐6 and C‐reactive protein in early diagnosis of neonatal sepsis. Journal of Clinical Laboratory Analysis 24:6, pages 363-370.
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M. Icardi, Y. Erickson, S. Kilborn, B. Stewart, B. Grief & G. Scharnweber. (2009) CD64 Index Provides Simple and Predictive Testing for Detection and Monitoring of Sepsis and Bacterial Infection in Hospital Patients. Journal of Clinical Microbiology 47:12, pages 3914-3919.
Crossref
Mojca Groselj-Grenc, Alojz Ihan, Maja Pavcnik-Arnol, Andreja Natasa Kopitar, Tanja Gmeiner-Stopar & Metka Derganc. (2009) Neutrophil and monocyte CD64 indexes, lipopolysaccharide-binding protein, procalcitonin and C-reactive protein in sepsis of critically ill neonates and children. Intensive Care Medicine 35:11, pages 1950-1958.
Crossref
S. TanakaJ. NishinoT. MatsuiA. KomiyaK. NishimuraS. Tohma. (2009) Neutrophil CD64 expression in the diagnosis of local musculoskeletal infection and the impact of antibiotics. The Journal of Bone and Joint Surgery. British volume 91-B:9, pages 1237-1242.
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Johannes J.M.L. Hoffmann. (2009) Neutrophil CD64: a diagnostic marker for infection and sepsis. Clinical Chemistry and Laboratory Medicine 47:8.
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Mojca Groselj-Grenc, Alojz Ihan & Metka Derganc. (2008) Neutrophil and Monocyte CD64 and CD163 Expression in Critically Ill Neonates and Children with Sepsis: Comparison of Fluorescence Intensities and Calculated Indexes. Mediators of Inflammation 2008, pages 1-10.
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John E Pandolfino, Sudip K Ghosh, John Rice, John O Clarke, Monika A Kwiatek & Peter J Kahrilas. (2008) Classifying Esophageal Motility by Pressure Topography Characteristics: A Study of 400 Patients and 75 Controls. The American Journal of Gastroenterology 103:1, pages 27-37.
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