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Research Article

Safety Profile of Meropenem: a Review of Nearly 5,000 Patients Treated with Meropenem

Pages 3-10 | Published online: 08 Jul 2009

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Read on this site (9)

Garyphallia Poulakou & Helen Giamarellou. (2008) Doripenem: an expected arrival in the treatment of infections caused by multidrug-resistant Gram-negative pathogens. Expert Opinion on Investigational Drugs 17:5, pages 749-771.
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Jomy Joseph & Keith A Rodvold. (2008) The role of carbapenems in the treatment of severe nosocomial respiratory tract infections. Expert Opinion on Pharmacotherapy 9:4, pages 561-575.
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David P Nicolau. (2008) Carbapenems: a potent class of antibiotics. Expert Opinion on Pharmacotherapy 9:1, pages 23-37.
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Alberto E. Fica & Nancy J. Abusada. (2008) Seizures associated with ertapenem use in patients with CNS disorders and renal insufficiency. Scandinavian Journal of Infectious Diseases 40:11-12, pages 983-985.
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Philip D Lister. (2007) Carbapenems in the USA: focus on doripenem. Expert Review of Anti-infective Therapy 5:5, pages 793-809.
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Ioannis P Kioumis, Joseph L Kuti & David P Nicolau. (2007) Intra-abdominal infections: considerations for the use of the carbapenems. Expert Opinion on Pharmacotherapy 8:2, pages 167-182.
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Douglas N Fish. (2006) Meropenem in the treatment of complicated skin and soft tissue infections. Therapeutics and Clinical Risk Management 2:4, pages 401-415.
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Steven J. Edwards, Cathy E. Emmas & Helen E. Campbell. (2005) Systematic review comparing meropenem with imipenem plus cilastatin in the treatment of severe infections. Current Medical Research and Opinion 21:5, pages 785-794.
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Peter Lanbeck, Inga Odenholt & Otto Paulsen. (2002) Antibiotics Differ in Their Tendency to Cause Infusion Phlebitis: A Prospective Observational Study. Scandinavian Journal of Infectious Diseases 34:7, pages 512-519.
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Emily N. Larsen, Nicole Marsh, Gabor Mihala, Michelle King, Matthew Zunk, Amanda J. Ullman, Samantha Keogh, Tricia M. Kleidon & Claire M. Rickard. (2022) Intravenous antimicrobial administration through peripheral venous catheters – establishing risk profiles from an analysis of 5252 devices. International Journal of Antimicrobial Agents 59:4, pages 106552.
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Mahila Monajati, Shahram Ala, Masoud Aliyali, Roya Ghasemian, Fatemeh Heidari, Mohammad Ahanjan, Siavash Moradi, Ali Sharifpour, Mojtaba Mojtahedzadeh & Ebrahim Salehifar. (2021) Clinical Effectiveness of a High Dose Versus the Standard Dose of Meropenem in Ventilator-associated Pneumonia Caused by Multidrugresistant Bacteria: A Randomized, Single-blind Clinical Trial. Infectious Disorders - Drug Targets 21:2, pages 274-283.
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Vanda Ho, Felecia Tay, Jia En Wu, Lionel Lum & Paul Tambyah. (2020) The Case for Intermittent Carbapenem Dosing in Stable Haemodialysis Patients. Antibiotics 9:11, pages 815.
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Xiangqing Song, Yi Wu, Lizhi Cao, Dunwu Yao & Minghui Long. (2019) Is Meropenem as a Monotherapy Truly Incompetent for Meropenem-Nonsusceptible Bacterial Strains? A Pharmacokinetic/Pharmacodynamic Modeling With Monte Carlo Simulation. Frontiers in Microbiology 10.
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Gerda Wurpts, Werner Aberer, Heinrich Dickel, Randolf Brehler, Thilo Jakob, Burkhard Kreft, Vera Mahler, Hans F. Merk, Norbert Mülleneisen, Hagen Ott, Wolfgang Pfützner, Stefani Röseler, Franziska Ruëff, Helmut Sitter, Cord Sunderkötter, Axel Trautmann, Regina Treudler, Bettina Wedi, Margitta Worm & Knut Brockow. (2019) Guideline on diagnostic procedures for suspected hypersensitivity to beta-lactam antibiotics. Allergo Journal International 28:5, pages 121-151.
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Gerda Wurpts, Werner Aberer, Heinrich Dickel, Randolf Brehler, Thilo Jakob, Burkhard Kreft, Vera Mahler, Hans F. Merk, Norbert Mülleneisen, Hagen Ott, Wolfgang Pfützner, Stefani Röseler, Franziska Ruëff, Helmut Sitter, Cord Sunderkötter, Axel Trautmann, Regina Treudler, Bettina Wedi, Margitta Worm & Knut Brockow. (2019) S2k-Leitlinie: Diagnostik bei Verdacht auf eine Betalaktamantibiotika-Überempfindlichkeit. Allergo Journal 28:5, pages 19-51.
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Ichiro Nakakura, Yoshihiko Ogawa, Kota Sakakura, Kaori Imanishi, Kazuyuki Hirota, Yasuaki Shimatani, Tomoko Uehira, Shoji Nakamori, Rumi Sako, Toshiyuki Doi & Kunio Yamazaki. (2017) IMP-6 Carbapenemase-Producing Enterobacteriaceae Bacteremia Successfully Treated with Amikacin-Meropenem in Two Patients . Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy 37:10, pages e96-e102.
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Denise H. Rhoney & Greene Shepherd. 2017. Seizures in Critical Care. Seizures in Critical Care 321 341 .
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Blanca Noguerado-Mellado, Celia Pinto Fernández, Rafael Pineda-Pineda, Patricia Martínez Lezcano, Alberto Álvarez-Perea & Manuel De Barrio Fernández. (2014) Cross-reactivity between carbapenems: Two case reports. The Journal of Allergy and Clinical Immunology: In Practice 2:6, pages 816-817.
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Arun Mattappalil & Kari A. Mergenhagen. (2014) Neurotoxicity with Antimicrobials in the Elderly: A Review. Clinical Therapeutics 36:11, pages 1489-1511.e4.
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Akihiro Tanaka, Kenshi Takechi, Shinichi Watanabe, Mamoru Tanaka, Katsuya Suemaru & Hiroaki Araki. (2013) Comparison of the prevalence of convulsions associated with the use of cefepime and meropenem. International Journal of Clinical Pharmacy 35:5, pages 683-687.
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Han Yee Neo, Keng Teng Tan & Yew Yoong Ding. (2013) Higher than expected rates of seizures associated with the use of ertapenem in older hospitalized patients. Journal of Clinical Gerontology and Geriatrics 4:1, pages 17-21.
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Ivan Chytra, Martin Stepan, Jan Benes, Petr Pelnar, Alexandra Zidkova, Tamara Bergerova, Richard Pradl & Eduard Kasal. (2012) Clinical and microbiological efficacy of continuous versus intermittent application of meropenem in critically ill patients: a randomized open-label controlled trial. Critical Care 16:3, pages R113.
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April D. Miller, Amanda M. Ball, P. Brandon Bookstaver, Emily K. Dornblaser & Charles L. Bennett. (2012) Epileptogenic Potential of Carbapenem Agents: Mechanism of Action, Seizure Rates, and Clinical Considerations. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy 31:4, pages 408-423.
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Tore Midtvedt. 2011. A worldwide yearly survey of new data in adverse drug reactions. A worldwide yearly survey of new data in adverse drug reactions 491 508 .
A. Pallett & K. Hand. (2010) Complicated urinary tract infections: practical solutions for the treatment of multiresistant Gram-negative bacteria. Journal of Antimicrobial Chemotherapy 65:Supplement 3, pages iii25-iii33.
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Denise H. Rhoney & Panayiotis N. Varelas. 2010. Seizures in Critical Care. Seizures in Critical Care 307 340 .
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George G. Zhanel, Nzeera Ketter, Ethan Rubinstein, Ian Friedland & Rebecca Redman. (2009) Overview of Seizure-Inducing Potential of Doripenem. Drug Safety 32:9, pages 709-716.
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Jane Frumin & Jason C Gallagher. (2009) Allergic Cross-Sensitivity Between Penicillin, Carbapenem, and Monobactam Antibiotics: What are the Chances?. Annals of Pharmacotherapy 43:2, pages 304-315.
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Jie Gu & Yanyan Huang. (2009) Effect of concomitant administration of meropenem and valproic acid in an elderly chinese patient. The American Journal of Geriatric Pharmacotherapy 7:1, pages 26-33.
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Philip Toltzis, Michael Dul, Mary Ann O’Riordan, David Melnick, Mathew Lo & Jeffrey Blumer. (2009) Meropenem use and colonization by antibiotic-resistant Gram-negative bacilli in a pediatric intensive care unit*. Pediatric Critical Care Medicine 10:1, pages 49-54.
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Ergun Nacarkucuk, Halil Saglam & Mehmet Okan. (2004) Meropenem Decreases Serum Level of Valproic Acid. Pediatric Neurology 31:3, pages 232-234.
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