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Scandinavian Journal of Urology and Nephrology Volume 36, 2002 - Issue 2
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Research Article

A Comparative Randomized and Placebo-controlled Short-term Trial of Aspirin and Dipyridamole for Overt Type-2 Diabetic Nephropathy

P. Khajehdehi Divisions of Nephrology and Endocrinology, Department of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran
,
J. Roozbeh Divisions of Nephrology and Endocrinology, Department of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran
&
H. Mostafavi Divisions of Nephrology and Endocrinology, Department of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran
Pages 145-148 | Published online: 09 Jul 2009

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Dan Mo, Songfang Liu, Hong Ma, Haoming Tian, Honglin Yu, Xiangxun Zhang, Nanwei Tong, Jiayu Liao & Yan Ren. (2019) Effects of acarbose and metformin on the inflammatory state in newly diagnosed type 2 diabetes patients: a one-year randomized clinical study. Drug Design, Development and Therapy 13, pages 2769-2776.
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Articles from other publishers (25)

Md. Golam Rabby, Md. Hafizur Rahman, Md. Numan Islam, Md. Mostafa Kamal, Mrityunjoy Biswas, Mantasa Bonny & Md. Mahmudul Hasan. (2023) In silico identification and functional prediction of differentially expressed genes in South Asian populations associated with type 2 diabetes. PLOS ONE 18:12, pages e0294399.
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Rafał Frankowski, Mateusz Kobierecki, Andrzej Wittczak, Monika Różycka-Kosmalska, Tadeusz Pietras, Kasper Sipowicz & Marcin Kosmalski. (2023) Type 2 Diabetes Mellitus, Non-Alcoholic Fatty Liver Disease, and Metabolic Repercussions: The Vicious Cycle and Its Interplay with Inflammation. International Journal of Molecular Sciences 24:11, pages 9677.
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Hsing-Yi Huang, Tz-Wen Lu, Hsiu-Ling Liang, Wei-Hao Hsu, Ya-Wen Sung & Mei-Yueh Lee. (2022) Antiplatelet agents aspirin and dipyridamole, and the risk of different carcinoma in patients with type 2 diabetes mellitus: A Taiwan retrospective cohort study. Medicine 101:37, pages e30468.
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Ukhti Jamil Rustiasari & Joris J. Roelofs. (2022) The Role of Platelets in Diabetic Kidney Disease. International Journal of Molecular Sciences 23:15, pages 8270.
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Patrizia Natale, Suetonia C Palmer, Valeria M Saglimbene, Marinella Ruospo, Mona Razavian, Jonathan C Craig, Meg J Jardine, Angela C Webster & Giovanni FM Strippoli. (2022) Antiplatelet agents for chronic kidney disease. Cochrane Database of Systematic Reviews 2022:2.
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R.G. Esin, I.Kh. Khairullin & O.R. Esin. (2021) Diabetic encephalopathy: current insights and potential therapeutic strategies. Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova 121:7, pages 49.
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Xiaole Su, Bingjuan Yan, Lihua Wang, Jicheng Lv, Hong Cheng & Yipu Chen. (2019) Effect of antiplatelet therapy on cardiovascular and kidney outcomes in patients with chronic kidney disease: a systematic review and meta-analysis. BMC Nephrology 20:1.
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Kun Ling Ma, Liang Liu, Yang Zhang, Gui Hua Wang, Ze Bo Hu, Pei Pei Chen, Jian Lu, Chen Chen Lu, Tie Kai Gong, Yu Xiang Gong & Bi Cheng Liu. (2019) Aspirin attenuates podocyte injury in diabetic rats through overriding cyclooxygenase-2-mediated dysregulation of LDL receptor pathway. International Urology and Nephrology 51:3, pages 551-558.
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Yang Zhang, Kun Ling Ma, Yu Xiang Gong, Gui Hua Wang, Ze Bo Hu, Liang Liu, Jian Lu, Pei Pei Chen, Chen Chen Lu, Xiong Zhong Ruan & Bi Cheng Liu. (2018) Platelet Microparticles Mediate Glomerular Endothelial Injury in Early Diabetic Nephropathy. Journal of the American Society of Nephrology 29:11, pages 2671-2695.
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Francesco Violi, Giovanni Targher, Annarita Vestri, Roberto Carnevale, Maurizio Averna, Alessio Farcomeni, Andrea Lenzi, Francesco Angelico, Francesco Cipollone & Daniele Pastori. (2017) Effect of aspirin on renal disease progression in patients with type 2 diabetes: A multicenter, double-blind, placebo-controlled, randomized trial. The renaL disEase progression by aspirin in diabetic pAtients (LEDA) trial. Rationale and study design. American Heart Journal 189, pages 120-127.
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Estifanos Baye, Negar Naderpoor, Marie Misso, Helena Teede, Lisa J. Moran & Barbora de Courten. (2017) Treatment with high dose salicylates improves cardiometabolic parameters: Meta-analysis of randomized controlled trials. Metabolism 71, pages 94-106.
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Pitchai Balakumar, Wei Ern WitnessKoe, Yi Syen Gan, Soo Mei JemayPuah, Subramaniam Kuganesswari, Sunil Kumar Prajapati, Rajavel Varatharajan, Sam Annie Jayachristy, Karupiah Sundram & Mohd Baidi Bahari. (2017) Effects of pre and post-treatments with dipyridamole in gentamicin-induced acute nephrotoxicity in the rat. Regulatory Toxicology and Pharmacology 84, pages 35-44.
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Nikkita Puri, Vinita Mohey, Manjinder Singh, Tajpreet Kaur, Devendra Pathak, Harpal Singh Buttar & Amrit Pal Singh. (2016) Dipyridamole attenuates ischemia reperfusion induced acute kidney injury through adenosinergic A1 and A2A receptor agonism in rats. Naunyn-Schmiedeberg's Archives of Pharmacology 389:4, pages 361-368.
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Juan F. Navarro-González, Carmen Mora-Fernández, Mercedes Muros de Fuentes, Jesús Chahin, María L. Méndez, Eduardo Gallego, Manuel Macía, Nieves del Castillo, Antonio Rivero, María A. Getino, Patricia García, Ana Jarque & Javier García. (2015) Effect of Pentoxifylline on Renal Function and Urinary Albumin Excretion in Patients with Diabetic Kidney Disease. Journal of the American Society of Nephrology 26:1, pages 220-229.
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Pitchai Balakumar, Rajavel Varatharajan, Ying Hui Nyo, Raja Renushia, Devarajan Raaginey, Ann Nah Oh, Shaikh Sohrab Akhtar, Mani Rupeshkumar, Karupiah Sundram & Sokkalingam A. Dhanaraj. (2014) Fenofibrate and dipyridamole treatments in low-doses either alone or in combination blunted the development of nephropathy in diabetic rats. Pharmacological Research 90, pages 36-47.
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Pitchai Balakumar, Ying Hui Nyo, Raja Renushia, Devarajan Raaginey, Ann Nah Oh, Rajavel Varatharajan & Sokkalingam A. Dhanaraj. (2014) Classical and pleiotropic actions of dipyridamole: Not enough light to illuminate the dark tunnel?. Pharmacological Research 87, pages 144-150.
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Arun Kumar Sharma, Deepa Khanna & Pitchai Balakumar. (2014) Low-dose dipyridamole treatment partially prevents diabetes mellitus-induced vascular endothelial and renal abnormalities in rats. International Journal of Cardiology 172:2, pages 530-532.
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Erica Rurali, Marina Noris, Antonietta Chianca, Roberta Donadelli, Federica Banterla, Miriam Galbusera, Giulia Gherardi, Sara Gastoldi, Aneliya Parvanova, Ilian Iliev, Antonio Bossi, Carolina Haefliger, Roberto Trevisan, Giuseppe RemuzziPiero Ruggenenti. (2013) ADAMTS13 Predicts Renal and Cardiovascular Events in Type 2 Diabetic Patients and Response to Therapy. Diabetes 62:10, pages 3599-3609.
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Suetonia C Palmer, Lucia Di Micco, Mona Razavian, Jonathan C Craig, Vlado Perkovic, Fabio Pellegrini, Meg J Jardine, Angela C Webster, Sophia Zoungas & Giovanni FM Strippoli. 1996. Cochrane Database of Systematic Reviews. Cochrane Database of Systematic Reviews.
Fang Fang, Yu Lu, De-lin Ma, Ting-ting Du, Shi-ying Shao & Xue-feng Yu. (2013) A meta-analysis of salicylates for type 2 diabetes mellitus. Journal of Huazhong University of Science and Technology [Medical Sciences] 33:1, pages 1-14.
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Shotaro Taniguchi, Teruto Hashiguchi, Tomoko Ono, Kazunori Takenouchi, Koujin Nakayama, Takahisa Kawano, Kaori Kato, Ryuji Matsushita, Masanao Nagatomo, Shuji Nakamura, Tomonori Nakashima & Ikuro Maruyama. (2010) Association between reduced ADAMTS13 and diabetic nephropathy. Thrombosis Research 125:6, pages e310-e316.
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Eduardo G. Camargo, Jorge Luiz Gross, Letícia S. Weinert, Joel Lavinsky & Sandra P. Silveiro. (2007) Aspirina em baixa dosagem em pacientes com diabete melito: riscos e benefícios em relação às complicações macro e microvasculares. Arquivos Brasileiros de Endocrinologia & Metabologia 51:3, pages 457-465.
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Shanqin Xu, Bingbing Jiang, Karlene A. Maitland, Hossein Bayat, Jiali Gu, Jerry L. Nadler, Stefano Corda, Gilbert Lavielle, Tony J. Verbeuren, Adriana Zuccollo & Richard A. Cohen. (2006) The Thromboxane Receptor Antagonist S18886 Attenuates Renal Oxidant Stress and Proteinuria in Diabetic Apolipoprotein E-Deficient Mice. Diabetes 55:1, pages 110-119.
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P. Ferroni, S. Basili, A. Falco & G. Davì. (2004) Platelet activation in type 2 diabetes mellitus. Journal of Thrombosis and Haemostasis 2:8, pages 1282-1291.
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M Luiza Caramori & Michael Mauer. (2003) Diabetes and nephropathy. Current Opinion in Nephrology and Hypertension 12:3, pages 273-282.
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