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Scandinavian Journal of Urology and Nephrology Volume 42, 2008 - Issue 4
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Review Article

Urological implications of cyclophosphamide and ifosfamide

Malcolm Lawson Department of Urology, Princess Alexandra Hospital, Brisbane, Queensland, Australia
,
Arthur Vasilaras Department of Urology, Princess Alexandra Hospital, Brisbane, Queensland, Australia
,
Annamarie De Vries Department of Urology, Princess Alexandra Hospital, Brisbane, Queensland, Australia; University of Queensland, Brisbane, Queensland, Australia
,
Peter MacTaggart Department of Urology, Princess Alexandra Hospital, Brisbane, Queensland, Australia; Department of Urology, Queen Elizabeth II Hospital, Brisbane, Queensland, Australia; University of Queensland, Brisbane, Queensland, Australia
&
David Nicol Department of Urology, Princess Alexandra Hospital, Brisbane, Queensland, Australia; University of Queensland, Brisbane, Queensland, AustraliaCorrespondence[email protected]
Pages 309-317 | Received 15 Nov 2006, Published online: 09 Jul 2009

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Moustapha Hassan & Borje S Andersson. (2013) Role of Pharmacogenetics in Busulfan/Cyclophosphamide Conditioning Therapy Prior to Hematopoietic Stem Cell Transplantation. Pharmacogenomics 14:1, pages 75-87.
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Articles from other publishers (43)

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Mohammad Amin Mombeini, Hadi Kalantar, Elahe Sadeghi, Mehdi Goudarzi, Hamidreza Khalili & Mojtaba Kalantar. (2022) Protective effects of berberine as a natural antioxidant and anti-inflammatory agent against nephrotoxicity induced by cyclophosphamide in mice. Naunyn-Schmiedeberg's Archives of Pharmacology 395:2, pages 187-194.
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Gilcy George Kallivalappil & Girija Kuttan. (2017) Evaluation of the anti-inflammatory and urotoxicity ameliorative effects of γ-humulene containing active fraction of Emilia sonchifolia (L.) DC.. Inflammopharmacology 27:2, pages 409-420.
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Haifa A.S. ALHaithloul, Mohammed F. Alotaibi, May Bin-Jumah, Hassan Elgebaly & Ayman M. Mahmoud. (2019) Olea europaea leaf extract up-regulates Nrf2/ARE/HO-1 signaling and attenuates cyclophosphamide-induced oxidative stress, inflammation and apoptosis in rat kidney. Biomedicine & Pharmacotherapy 111, pages 676-685.
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Ehsan Elahi & Sidrah Andleeb. (2018) Oncology Drug Shortages—What We Have Versus What We Expect to Have? A Critical Scenario of Pakistan. Journal of Pharmacy Technology 35:1, pages 41-42.
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Evaristus C. Mbanefo, Loc Le, Luke F. Pennington, Justin I. Odegaard, Theodore S. Jardetzky, Abdulaziz Alouffi, Franco H. Falcone & Michael H. Hsieh. (2018) Therapeutic exploitation of IPSE, a urogenital parasite‐derived host modulatory protein, for chemotherapy‐induced hemorrhagic cystitis. The FASEB Journal 32:8, pages 4408-4419.
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Mehdi Goudarzi, Mohammad Javad Khodayar, Seyed Mohammad Taghi Hosseini Tabatabaei, Habib Ghaznavi, Iman Fatemi & Saeed Mehrzadi. (2017) Pretreatment with melatonin protects against cyclophosphamide‐induced oxidative stress and renal damage in mice. Fundamental & Clinical Pharmacology 31:6, pages 625-635.
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Mohammad Afkhami-Ardakani, Shapour Hassanzadeh, Rasoul Shahrooz, Majid Asadi-Samani, Ebrahim Latifi & Tahra Luther. (2017) Phytotherapy and phytopharmacology for reduction of cyclophosphamide-induced toxicity in the male urinary system. Journal of Renal Injury Prevention 6:3, pages 164-170.
Crossref
Janet Kim & Jonathan J Chan. (2016) Cyclophosphamide in dermatology. Australasian Journal of Dermatology 58:1, pages 5-17.
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Ayman M. Mahmoud, Mousa O. Germoush, Mohammed F. Alotaibi & Omnia E. Hussein. (2017) Possible involvement of Nrf2 and PPARγ up-regulation in the protective effect of umbelliferone against cyclophosphamide-induced hepatotoxicity. Biomedicine & Pharmacotherapy 86, pages 297-306.
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Mojtaba Kalantar, Mehdi Goudarzi, Mohammad Javad Khodayar, Javad Babaei, Hossein Foruozandeh, Nima Bakhtiari & Hadis Alidadi. (2016) Protective Effects of the Hydroalcoholic Extract of Capparis spinosa L. Against Cyclophosphamide-Induced Nephrotoxicity in Mice. Jundishapur Journal of Natural Pharmaceutical Products 11:4.
Crossref
H Park, YS Kyung & G Lee. (2015) Urinary uroplakin expression in cyclophosphamide-induced rat cystitis model. Human & Experimental Toxicology 35:6, pages 613-622.
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Aya Y. Michaels, Abhishek R. Keraliya, Sree Harsha Tirumani, Atul B. Shinagare & Nikhil H. Ramaiya. (2015) Systemic treatment in breast cancer: a primer for radiologists. Insights into Imaging 7:1, pages 131-144.
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Sultan Alqahtani & Ayman M. Mahmoud. (2016) Gamma-Glutamylcysteine Ethyl Ester Protects against Cyclophosphamide-Induced Liver Injury and Hematologic Alterations via Upregulation of PPAR γ and Attenuation of Oxidative Stress, Inflammation, and Apoptosis . Oxidative Medicine and Cellular Longevity 2016, pages 1-14.
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SG Shapiro, DW Knapp & Matthew Breen. (2015) A cultured approach to canine urothelial carcinoma: molecular characterization of five cell lines. Canine Genetics and Epidemiology 2:1.
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Jemianne Bautista Jia, Chandana Lall, Temel Tirkes, Rajesh Gulati, Ramit Lamba & Scott C. Goodwin. (2015) Chemotherapy-related complications in the kidneys and collecting system: an imaging perspective. Insights into Imaging 6:4, pages 479-487.
Crossref
S. Bogiatzi, O. Pagonopoulou, M. Simopoulou, D. Kareli, A. Kouskoukis, Z. Koutka, P. Ipsilantis & T. Lialiaris. (2013) The cytogenetic action of ifosfamide, mesna, and their combination on peripheral rabbit lymphocytes: an in vivo/in vitro cytogenetic study. Cytotechnology 66:5, pages 753-760.
Crossref
S. Laberke, I. Zenker & J. Hirschberger. (2014) Mesna and furosemide for prevention of cyclophosphamide‐induced sterile haemorrhagic cystitis in dogs – a retrospective study. Veterinary Record 174:10, pages 250-250.
Crossref
Espedito Ladier do Nascimento, Mirian Watanabe, Cassiane Dezoti da Fonseca, Fabio dos Santos Schlottfeldt & Maria de Fátima Fernandes Vattimo. (2014) Renoprotective effect of the Echinodorus macrophyllus in induced renal injury. Acta Paulista de Enfermagem 27:1, pages 12-17.
Crossref
A Thompson, A Adamson, A Bahl, J Borwell, D Dodds, C Heath, R Huddart, R Mcmenemin, P Patel, J Peters & H Payne. (2016) Guidelines for the diagnosis, prevention and management of chemical- and radiation-induced cystitis. Journal of Clinical Urology 7:1, pages 25-35.
Crossref
Chunkit Fung & Kishan J. Pandya. 2014. ALERT - Adverse Late Effects of Cancer Treatment. ALERT - Adverse Late Effects of Cancer Treatment 123 152 .
Łukasz Dobrek, Agnieszka Baranowska & Piotr Thor. (2013) The influence of pemirolast on autonomic imbalance in rat cystitis model. Open Medicine 8:6, pages 766-775.
Crossref
Dhakshina Moorthy Ganeshan, Usama Salem, Chitra Viswanathan, Aparna Balachandran, Naveen Garg, Paul Silverman & Priya Bhosale. (2012) Complications of oncologic therapy in the abdomen and pelvis: a review. Abdominal Imaging 38:1, pages 1-21.
Crossref
Orhun Sinanoglu, Arzu Neşe Yener, Sinan Ekici, Ahmet Midi & Fehime Benli Aksungar. (2012) The Protective Effects of Spirulina in Cyclophosphamide Induced Nephrotoxicity and Urotoxicity in Rats. Urology 80:6, pages 1392.e1-1392.e6.
Crossref
Diren Beyoğlu & Jeffrey R. Idle. (2012) The glycine deportation system and its pharmacological consequences. Pharmacology & Therapeutics 135:2, pages 151-167.
Crossref
T.P. Hamsa & Girija Kuttan. (2012) Tinospora cordifolia ameliorates urotoxic effect of cyclophosphamide by modulating GSH and cytokine levels. Experimental and Toxicologic Pathology 64:4, pages 307-314.
Crossref
Vinícios T. Boeira, Carlos E. Leite, André A. SantosJrJr, Maria I. Edelweiss, João B. Calixto, Maria M. Campos & Fernanda B. Morrone. (2011) Effects of the hydroalcoholic extract of Phyllanthus niruri and its isolated compounds on cyclophosphamide-induced hemorrhagic cystitis in mouse. Naunyn-Schmiedeberg's Archives of Pharmacology 384:3.
Crossref
Jean M. Torrisi, Lawrence H. Schwartz, Marc J. Gollub, Michelle S. Ginsberg, George J. Bosl & Hedvig Hricak. (2011) CT Findings of Chemotherapy-induced Toxicity: What Radiologists Need to Know about the Clinical and Radiologic Manifestations of Chemotherapy Toxicity. Radiology 258:1, pages 41-56.
Crossref
. (2010) Current World Literature. Current Opinion in Rheumatology 22:1, pages 97-105.
Crossref
R. Jouenne, Ch. Pagnoux & L. Guillevin. 2010. Les Uvéites. Les Uvéites 645 660 .
. (2009) Current awareness: Pharmacoepidemiology and drug safety. Pharmacoepidemiology and Drug Safety 18:2.
Crossref

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