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Experimental Research Article

Zoledronic acid induces caspase-dependent apoptosis in renal cancer cell lines

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Pages 98-103 | Received 01 Apr 2008, Published online: 09 Jul 2009

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Jonathan Green & Allan Lipton. (2010) Anticancer Properties of Zoledronic Acid. Cancer Investigation 28:9, pages 944-957.
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Mehtap Kara, Tuğçe Boran, Ezgi Öztaş, Ayse Tarbin Jannuzzi, Sibel Özden & Gül Özhan. (2022) Zoledronic acid‐induced oxidative damage and endoplasmic reticulum stress‐mediated apoptosis in human embryonic kidney (HEK‐293) cells. Journal of Biochemical and Molecular Toxicology 36:8.
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Soma Shiva Nageswara Rao Singireesu, Sujan Kumar Mondal, Suresh Yerramsetty & Sunil Misra. (2018) Zoledronic acid induces micronuclei formation, mitochondrial-mediated apoptosis and cytostasis in kidney cells. Life Sciences 203, pages 305-314.
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Masood Umer, Yasir Mohib, Muhammed Atif & Muhammad Nazim. (2018) Skeletal metastasis in renal cell carcinoma: A review. Annals of Medicine and Surgery 27, pages 9-16.
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Xiang Gao, Bo Jiang, Shitao Zou, Ting Zhang, Xiaowei Qi, Linfang Jin, Xiaosong Ge, Shou-Ching Tang, Dong Hua & Weichang Chen. (2015) Zoledronate can promote apoptosis and inhibit the proliferation of colorectal cancer cells. Tumor Biology 36:7, pages 5315-5322.
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Jamal Zekri, Maged Mansour & Syed Mustafa Karim. (2014) The anti-tumour effects of zoledronic acid. Journal of Bone Oncology 3:1, pages 25-35.
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Daniel Keizman, Maya Ish-Shalom, Natalie Maimon & Maya Gottfried. (2013) Are bisphosphonates an indispensable tool in the era of targeted therapy for renal cell carcinoma and bone metastases?. World Journal of Urology 32:1, pages 39-45.
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Yosuke Yasuda, Yasuhisa Fujii, Takeshi Yuasa, Shinichi Kitsukawa, Shinji Urakami, Shinya Yamamoto, Junji Yonese, Shunji Takahashi & Iwao Fukui. (2012) Possible improvement of survival with use of zoledronic acid in patients with bone metastases from renal cell carcinoma. International Journal of Clinical Oncology 18:5, pages 877-883.
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Eduard Vrdoljak, Brian Rini, Manuela Schmidinger, Tomislav Omrčen, Laszlo Torday, Cezary Szczylik & Avishay Sella. (2013) Bisphosphonates and vascular endothelial growth factor-targeted drugs in the treatment of patients with renal cell carcinoma metastatic to bone. Anti-Cancer Drugs 24:5, pages 431-440.
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Peter F. Mulders. (2012) Current approaches to bone-targeted therapy in genitourinary malignancies. Therapeutic Advances in Urology 4:5, pages 219-232.
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Daniel Keizman, Maya Ish-Shalom, Roberto Pili, Hans Hammers, Mario A. Eisenberger, Victoria Sinibaldi, Ben Boursi, Natalie Maimon, Maya Gottfried, Henry Hayat, Avivit Peer, Svetlana Kovel, Avishay Sella, Raanan Berger & Michael A. Carducci. (2012) Bisphosphonates combined with sunitinib may improve the response rate, progression free survival and overall survival of patients with bone metastases from renal cell carcinoma. European Journal of Cancer 48:7, pages 1031-1037.
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Matti Aapro & Fred Saad. (2012) Bone-modifying agents in the treatment of bone metastases in patients with advanced genitourinary malignancies: a focus on zoledronic acid. Therapeutic Advances in Urology 4:2, pages 85-101.
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Fred Saad & Jean-Baptiste Lattouf. 2012. Prevention of Bone Metastases. Prevention of Bone Metastases 109 126 .
Fred Saad & James A. Eastham. (2010) Zoledronic Acid Use in Patients With Bone Metastases From Renal Cell Carcinoma or Bladder Cancer. Seminars in Oncology 37, pages S38-S44.
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