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Research Article

Effects of Phytic Acid on Renal Stone Formation in Rats

Pages 261-265 | Published online: 09 Jul 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

Jing Liu, Ying Li, Chunli Mei, Xianbin Ning, Jinfeng Pang, Lei Gu & Liang Wu. (2020) Phytic acid exerts protective effects in cerebral ischemia-reperfusion injury by activating the anti-oxidative protein sestrin2. Bioscience, Biotechnology, and Biochemistry 84:7, pages 1401-1408.
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Ivana Vucenik & AbulKalam M. Shamsuddin. (2006) Protection Against Cancer by Dietary IP6 and Inositol. Nutrition and Cancer 55:2, pages 109-125.
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B. Feil. (2001) Phytic Acid. Journal of New Seeds 3:3, pages 1-35.
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Articles from other publishers (38)

Liping Shan, Jianxiu Shi, Jia Li, Chunyu Pan, Yang Xia, Kaijun Niu, Zhenhua Li & Song Bai. (2023) Associations between grain intake and hospitalized nephrolithiasis in Chinese adults: a case-control study. Food & Function 14:8, pages 3863-3870.
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Mark Messina, Alison Duncan, Virginia Messina, Heidi Lynch, Jessica Kiel & John W. ErdmanJr.Jr.. (2022) The health effects of soy: A reference guide for health professionals. Frontiers in Nutrition 9.
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Ricardo D. Sosa, Jacinta C. Conrad, Michael A. Reynolds & Jeffrey D. Rimer. (2021) Suppressing barite crystallization with organophosphorus compounds. CrystEngComm 23:44, pages 7725-7730.
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Ehsan Feizollahi, Razieh Sadat Mirmahdi, Alaleh Zoghi, Ruurd T. Zijlstra, M.S. Roopesh & Thava Vasanthan. (2021) Review of the beneficial and anti-nutritional qualities of phytic acid, and procedures for removing it from food products. Food Research International 143, pages 110284.
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J. Lydia Pramitha, Sumi Rana, Pooja Rani Aggarwal, Rajasekaran Ravikesavan, A. John Joel & Mehanathan Muthamilarasan. 2021. 89 120 .
Saajidah Fakier & Allen Rodgers. (2020) Exploring the Potential Relationship Between Phytate Ingestion, Urinary Phytate Excretion, and Renal Stone Risk in a Unique Human Model: No Hard Evidence in Support of Phytate as a Stone Inhibitor. Journal of Renal Nutrition 30:5, pages 396-403.
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Ali Zein Alabiden Tlais, Giuseppina Maria Fiorino, Andrea Polo, Pasquale Filannino & Raffaella Di Cagno. (2020) High-Value Compounds in Fruit, Vegetable and Cereal Byproducts: An Overview of Potential Sustainable Reuse and Exploitation. Molecules 25:13, pages 2987.
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Mariano Bizzarri, Alessandro Giuliani, Noemi Monti, Roberto Verna, Andrea Pensotti & Alessandra Cucina. (2020) Rediscovery of natural compounds acting via multitarget recognition and noncanonical pharmacodynamical actions. Drug Discovery Today 25:5, pages 920-927.
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Haewook Han. 2020. Nutrition in Kidney Disease. Nutrition in Kidney Disease 471 506 .
Felix Grases & Antonia Costa-Bauza. (2019) Key Aspects of Myo-Inositol Hexaphosphate (Phytate) and Pathological Calcifications. Molecules 24:24, pages 4434.
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Jeffrey H. William. 2019. Nutritional and Medical Management of Kidney Stones. Nutritional and Medical Management of Kidney Stones 3 17 .
Xian-Wei Cheng, Cheng-Xi Liang, Jin-Ping Guan, Xu-Hong Yang & Ren-Cheng Tang. (2018) Flame retardant and hydrophobic properties of novel sol-gel derived phytic acid/silica hybrid organic-inorganic coatings for silk fabric. Applied Surface Science 427, pages 69-80.
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Simona Dinicola, Mirko Minini, Vittorio Unfer, Roberto Verna, Alessandra Cucina & Mariano Bizzarri. (2017) Nutritional and Acquired Deficiencies in Inositol Bioavailability. Correlations with Metabolic Disorders. International Journal of Molecular Sciences 18:10, pages 2187.
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Rinkesh Kumar Gupta, Kriti Gupta, Akanksha Sharma, Mukul Das, Irfan Ahmad Ansari & Premendra D. Dwivedi. (2016) Health Risks and Benefits of Chickpea ( Cicer arietinum ) Consumption . Journal of Agricultural and Food Chemistry 65:1, pages 6-22.
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Juan Manuel Buades Fuster, Pilar Sanchís Cortés, Joan Perelló Bestard & Félix Grases Freixedas. (2017) Plant phosphates, phytate and pathological calcifications in chronic kidney disease. Nefrología (English Edition) 37:1, pages 20-28.
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Juan Manuel Buades Fuster, Pilar Sanchís Cortés, Joan Perelló Bestard & Félix Grases Freixedas. (2017) Fosfatos de origen vegetal, fitato y calcificaciones patológicas en la enfermedad renal crónica. Nefrología 37:1, pages 20-28.
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Miranda S. C. Wilson, Simon J. Bulley, Francesca Pisani, Robin F. Irvine & Adolfo Saiardi. (2015) A novel method for the purification of inositol phosphates from biological samples reveals that no phytate is present in human plasma or urine. Open Biology 5:3, pages 150014.
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Felix Grases, Concepcion Saez-Torres, Adrian Rodriguez, Antonia Costa-Bauza, Dolores Rodrigo, Guillem Frontera, Francisco Berga & Saajidah Fakier. (2014) Urinary Phytate (Myo-Inositol Hexaphosphate) in Healthy School Children and Risk of Nephrolithiasis. Journal of Renal Nutrition 24:4, pages 219-223.
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Joan Perelló & Felix Grases. (2014) Phytate levels in biological fluids of mammals. Journal of Chromatography B 960, pages 255-257.
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Pietro Manuel Ferraro, Gianmarco Lombardi & Giovanni Gambaro. (2014) Prevention of nephrolithiasis: a review. Urologia Journal 81:2, pages 88-92.
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Fernando Tur, Eva Tur, Irene Lentheric, Paula Mendoza, Maximo Encabo, Bernat Isern, Felix Grases, Ciriaco Maraschiello & Joan Perelló. (2013) Validation of an LC–MS bioanalytical method for quantification of phytate levels in rat, dog and human plasma. Journal of Chromatography B 928, pages 146-154.
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Ángel A. López-González, Félix Grases, Nieves Monroy, Bartolome Marí, Mª Teófila Vicente-Herrero, Fernando Tur & Joan Perelló. (2012) Protective effect of myo-inositol hexaphosphate (phytate) on bone mass loss in postmenopausal women. European Journal of Nutrition 52:2, pages 717-726.
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Alan G. Wasserstein. (2011) Epidemiology and Natural History of Nephrolithiasis. Clinical Reviews in Bone and Mineral Metabolism 9:3-4, pages 165-180.
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Hans-Göran Tiselius. (2011) Who Forms Stones and Why?. European Urology Supplements 10:5, pages 408-414.
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William N. Addison & Marc D. McKee. (2010) Inositol hexakisphosphate inhibits mineralization of MC3T3-E1 osteoblast cultures. Bone 46:4, pages 1100-1107.
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Rosemary Lyons Ryall. 2011. Urinary Tract Stone Disease. Urinary Tract Stone Disease 31 60 .
Ulrich Schlemmer, Wenche Frølich, Rafel M. Prieto & Felix Grases. (2009) Phytate in foods and significance for humans: Food sources, intake, processing, bioavailability, protective role and analysis. Molecular Nutrition & Food Research 53:S2.
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E Thomas, G E von Unruh & A Hesse. (2007) Influence of a low- and a high-oxalate vegetarian diet on intestinal oxalate absorption and urinary excretion. European Journal of Clinical Nutrition 62:9, pages 1090-1097.
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Mohammed Touhami, Amine Laroubi, Khadija Elhabazi, Farouk Loubna, Ibtissam Zrara, Younes Eljahiri, Abdelkhalek Oussama, Félix Grases & Abderrahman Chait. (2007) Lemon juice has protective activity in a rat urolithiasis model. BMC Urology 7:1.
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Amine Laroubi, Mohammed Touhami, Loubna Farouk, Ibtissam Zrara, Rachida Aboufatima, Ahmmed Benharref & Abderrahman Chait. (2007) Prophylaxis effect of Trigonella foenum graecum L. seeds on renal stone formation in rats. Phytotherapy Research 21:10, pages 921-925.
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Felix Grases, Antonia Costa-Bauza & Rafel M Prieto. (2006) Renal lithiasis and nutrition. Nutrition Journal 5:1.
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Kenan Dost & Ozge Tokul. (2006) Determination of phytic acid in wheat and wheat products by reverse phase high performance liquid chromatography. Analytica Chimica Acta 558:1-2, pages 22-27.
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Felix Grases, Joan Perelló, Bernat Isern & Rafel M. Prieto. (2005) Study of the Absorption of Myo-Inositol Hexakisphosphate (InsP6) through the Skin. Biological and Pharmaceutical Bulletin 28:4, pages 764-767.
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F Grases, J Perelló, R.M Prieto, B.M Simonet & J.J Torres. (2004) Dietary myo-inositol hexaphosphate prevents dystrophic calcifications in soft tissues: a pilot study in Wistar rats. Life Sciences 75:1, pages 11-19.
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F. Grases, B.M. Simonet, J. Perelló, A. Costa-Bauzá & R.M. Prieto. (2004) Effect of phytate on element bioavailability in the second generation of rats. Journal of Trace Elements in Medicine and Biology 17:4, pages 229-234.
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Abulkalam M. Shamsuddin. (2002) Anti‐cancer function of phytic acid. International Journal of Food Science & Technology 37:7, pages 769-782.
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Mazda Jenab & Lililan Thompson. 2001. Food Phytates. Food Phytates.
Stephen B Shears. (2001) Assessing the omnipotence of inositol hexakisphosphate. Cellular Signalling 13:3, pages 151-158.
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