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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 30, 2000 - Issue 15
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Original Articles

Chemistry of Substituted Quinolinones. Part II Synthesis of Novel 4-Pyrazolylquinolinone Derivatives

Mohamed Abass Department of Chemistry, Faculty of Education, Ain Shams University, Roxy, 11711, Cairo, Egypt
Pages 2735-2757 | Received 03 Nov 1999, Published online: 16 Feb 2011

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Mohamed Abass, Mohamed Abdel‐Megid & Mohamed Hassan. (2007) Substituted Quinolinones, Part 12: Heterocyclization Reactions of 3‐(3‐Chromonyl)acryloylquinolinone with Some Bifunctional Nucleophiles. Synthetic Communications 37:2, pages 329-352.
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Mohamed Abass. (2003) Chemistry of Substituted Quinolinones. Part 8. Synthesis and Cyclization Reactions of Ethyl 5-Amino-1-(1-methyl-2-oxoquinolin-4-YL)-3-methylsulfanylpyrazole-4-carboxylate. Phosphorus, Sulfur, and Silicon and the Related Elements 178:7, pages 1413-1432.
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A. Khodairy. (2003) Synthesis of Polyfused Thieno(2,3- b )thiophenes Part 3: Synthesis of Thienopyrimidinotetrazole, Thienopyrimidinotriazepine, Thienopyrimidinotriazine, Thienopyrimidinotriazole and Pyrazolylthienopyrimidine Derivatives. Phosphorus, Sulfur, and Silicon and the Related Elements 178:4, pages 893-901.
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MostafaM. Ismail & Mohamed Abass. (2001) Chemistry of Substituted Quinolinones IV. Regioselective Nucleophilic Substitution of 1,3-Dichlorobenzo[f]quinoline. Polycyclic Aromatic Compounds 18:4, pages 469-480.
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Mohamed Abass & Elham S. Othman. (2001) CHEMISTRY OF SUBSTITUTED QUINOLINONES. III. SYNTHESIS AND REACTIONS OF SOME NOVEL 3-PYRAZOLYL-2-QUINOLINONES. Synthetic Communications 31:21, pages 3361-3376.
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M.M. Ismail, M. Abass & M.M. Hassan. (2000) Chemistry of Substituted Quinolinones. v. Synthesis and Use of Quinolinylphosphazenes in Amination of 8-Methylquinoline. Phosphorus, Sulfur, and Silicon and the Related Elements 167:1, pages 275-288.
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Articles from other publishers (53)

Mohammed A. I. Elbastawesy, Ashraf A. Aly, Yaseen A. M. M. El-Shaier, Alan B. Brown, Gamal El-Din A. Abuo-Rahma, Mohamed Samir & Mohamed Ramadan. (2023) Facile synthesis of 5-aminopyrazolo-quinolones. Monatshefte für Chemie - Chemical Monthly 154:10, pages 1197-1204.
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Mohammed A.I. Elbastawesy, Fatma A.M. Mohamed, Islam Zaki, Mohammed Issa Alahmdi, Seham S. Alzahrani, Hayat Ali Alzahrani, Hesham A.M. Gomaa & Bahaa G.M. Youssif. (2023) Design, synthesis and antimicrobial activity of novel quinoline-2-one hybrids as promising DNA gyrase and topoisomerase IV inhibitors. Journal of Molecular Structure 1278, pages 134902.
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Sara M. Mostafa, Ashraf A. Aly, Alaa A. Hassan, Esraa M. Osman, Stefan Bräse, Martin Nieger, Mahmoud A. A. Ibrahim & Asmaa H. Mohamed. (2022) Autoxidation of 4-Hydrazinylquinolin-2(1H)-one; Synthesis of Pyridazino[4,3-c:5,6-c′]diquinoline-6,7(5H,8H)-diones. Molecules 27:7, pages 2125.
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Essmat M. El-Sheref, Mohammed A. I. Elbastawesy, Alan B. Brown, Ahmed M. Shawky, Hesham A. M. Gomaa, Stefan Bräse & Bahaa G. M. Youssif. (2021) Design and Synthesis of (2-oxo-1,2-Dihydroquinolin-4-yl)-1,2,3-triazole Derivatives via Click Reaction: Potential Apoptotic Antiproliferative Agents. Molecules 26:22, pages 6798.
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Mohammed A.I. Elbastawesy, Ashraf A. Aly, Yaseen A.M.M. El-Shaier, Alan B. Brown, Gamal El-Din A. Abuo-Rahma & Mohamed Ramadan. (2021) New 4-thiazolidinone/quinoline-2-ones scaffold: Design, synthesis, docking studies and biological evaluation as potential urease inhibitors. Journal of Molecular Structure 1244, pages 130845.
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Sara M. Mostafa, Ashraf A. Aly, Samia M. Sayed, Mohamed A. Raslan, Amira E. Ahmed, Ayman Nafady, Esam A. Ishak, Ahmed M. Shawky & El-Shimaa M.N. Abdelhafez. (2021) New Quinoline-2-one/thiazolium bromide Derivatives; Synthesis, Characterization and Mechanism of Formation. Journal of Molecular Structure 1239, pages 130501.
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Mohammed B. Alshammari, Ashraf A. Aly, Alan B. Brown, Md Afroz Bakht, Ahmed M. Shawky, Adel M. Abdelhakem & Essmat M. El-Sheref. (2021) An efficient click synthesis of chalcones derivatized with two 1-(2-quinolon-4-yl)-1,2,3-triazoles. Zeitschrift für Naturforschung B 76:6-7, pages 395-403.
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Vrushabendra Basavanna, Srikantamurthy Ningaiah, Manasa Chandramouli, Anjali Sobha & Shridevi Doddamani. (2021) Quinolinyl-pyrazoles: synthesis and pharmacological evolution in the recent decennial. Journal of the Iranian Chemical Society 18:7, pages 1479-1522.
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Mohammed A. I. Elbastawesy, Yaseen A. M. M. El-Shaier, Mohamed Ramadan, Alan B. Brown, Ashraf A. Aly & Gamal El-Din A. Abuo-Rahma. (2020) Identification and molecular modeling of new quinolin-2-one thiosemicarbazide scaffold with antimicrobial urease inhibitory activity. Molecular Diversity 25:1, pages 13-27.
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Mohammed A.I. Elbastawesy, Mohamed Ramadan, Yaseen A.M.M. El-Shaier, Ashraf A. Aly & Gamal El-Din A. Abuo-Rahma. (2020) Arylidenes of Quinolin-2-one scaffold as Erlotinib analogues with activities against leukemia through inhibition of EGFR TK/ STAT-3 pathways. Bioorganic Chemistry 96, pages 103628.
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Ashraf A. Aly, Samia M. Sayed, El-Shimaa M.N. Abdelhafez, Sara Mohamed Naguib Abdelhafez, Walaa Yehia Abdelzaher, Mohamed A. Raslan, Amira E. Ahmed, Khaled Thabet, Ahmed A.M. El-Reedy, Alan B. Brown & Stefan Bräse. (2020) New quinoline-2-one/pyrazole derivatives; design, synthesis, molecular docking, anti-apoptotic evaluation, and caspase-3 inhibition assay. Bioorganic Chemistry 94, pages 103348.
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Mohammed A.I. Elbastawesy, Ashraf A. Aly, Mohamed Ramadan, Yaseen A.M.M. Elshaier, Bahaa G.M. Youssif, Alan B. Brown & Gamal El-Din A Abuo-Rahma. (2019) Novel Pyrazoloquinolin-2-ones: Design, synthesis, docking studies, and biological evaluation as antiproliferative EGFR-TK inhibitors. Bioorganic Chemistry 90, pages 103045.
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Heba Hassan. (2018) Unanticipated Heterocyclization from Reaction of Hydrazine Hydrate and/or Hydrazine Dihydrochloride with 1‐Ethyl‐4‐hydroxyquinolin‐2(1 H )‐one . Journal of Heterocyclic Chemistry 56:2, pages 646-650.
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Rahul WatpadeAvinash BholayRaghunath Toche. (2017) Synthesis of New Pyrano‐fused Quinolines as Antibacterial and Antimicrobial Agents. Journal of Heterocyclic Chemistry 54:6, pages 3434-3439.
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Khaled M. Elattar, Ramy Rabie & Mohamed M. Hammouda. (2016) Recent progress in the chemistry of bicyclic 6–6 systems: chemistry of pyrido[1,2-a]pyrimidines. Monatshefte für Chemie - Chemical Monthly 148:4, pages 601-627.
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Mohamed Abass, El-Hussain A Mohamed, Aisha S Mayas & Akram H Ibrahim. (2012) Substituted quinolinones. Part 17: Some nucleophilic reactions with 4-hydroxy-1-methyl-3-[(2-oxo-2H-chromen-3-yl)carbonyl]quinolin-2(1H)-one. Journal of Chemical Sciences 124:5, pages 1033-1041.
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Ramadan A. Mekheimer, Eltaib A. Ahmed & Kamal U. Sadek. (2012) Recent developments in the chemistry of pyrazolo[4,3-c]quinolines. Tetrahedron 68:6, pages 1637-1667.
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Raghunath B. Toche, Muddassar A. Kazi, Prashant S. Nikam & Dinesh C. Bhavsar. (2011) Synthesis of nicotinonitrile derivatives and study of their photophysical properties. Monatshefte für Chemie - Chemical Monthly 142:3, pages 261-269.
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Raghunath B. Toche, Muddassar A. Kazi, Shivaraj P. Patil, Shrikant B. Kanawade & Madhukar N. Jachak. (2010) Synthesis of Quinolone Substituted Pyrazoles, Isoxazoles and Pyridines as a Potential Blue Luminophors. Journal of Fluorescence 20:5, pages 1129-1137.
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Raghunath B. Toche, Muddassar A. Kazi, Bhausaheb K. Ghotekar, Sandeep M. Bagul, Chanda D. Tantak & Madhukar N. Jachak. (2009) Fluorescence Properties of Donor Acceptor Chromophores on Newly Synthesized Pyridine-3-Carbonitriles. Journal of Fluorescence 19:6, pages 1119-1124.
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Stefano Chimichi, Marco Boccalini & Alessandra Matteucci. (2008) Regioselective synthesis of 2,5-dihydro-4H-pyrazolo[4,3-c]quinolin-4-ones by the cyclization of 3-acyl-4-methoxy-1-methylquinolinones with hydrazines. Tetrahedron 64:39, pages 9275-9279.
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Mohamed Abass. (2005) Fused Quinolines. Recent Synthetic Approaches to Azoloquinolines. A Review. HETEROCYCLES 65:4, pages 901.
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Mohamed Abass. (2010) ChemInform Abstract: Chemistry of Substituted Quinolinones. Part 2. Synthesis of Novel 4‐Pyrazolylquinolinone Derivatives.. ChemInform 31:43.
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