Yamadazyma Farinosa IFO 10896-Mediated Reduction of 4,4-Dimethoxy-2-Butanone as the Key-Step for the Preparation of 1,3-Diols with Unsymmetrical Substituents

Takahiro Yamazaki Department of Chemistry, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama, 223–8522, Japan

Atsuhito Kuboki Department of Chemistry, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama, 223–8522, Japan

Hiromichi Ohta Department of Chemistry, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama, 223–8522, Japan

Thomas M. Mitzel Evans Chemical Laboratories, The Ohio State University, Columbus, Ohio, 43210, USA

Leo A. Paquette Evans Chemical Laboratories, The Ohio State University, Columbus, Ohio, 43210, USA

Takeshi Sugai Department of Chemistry, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama, 223–8522, Japan

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Jeremy Robertson, Stuart P. Green, Michael J. Hall, Andrew J. Tyrrell & William P. Unsworth. (2008) Further studies on silatropic carbonyl ene cyclisations: β-crotyl(diphenyl)silyloxy aldehyde substrates; synthesis of 2-deoxy-2-C-phenylhexoses. Organic & Biomolecular Chemistry 6:14, pages 2628.
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Kazutsugu Matsumoto, Yoichi Kawabata, Satoshi Okada, Jun Takahashi, Key Hashimoto, Yuto Nagai, Junichi Tatsuta & Minoru Hatanaka. (2007) Enantioselective Microbial Oxidation of Allyl Alcohols. Chemistry Letters 36:12, pages 1428-1429.
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Masaaki Matsuda, Takahiro Yamazaki, Ken-ichi Fuhshuku & Takeshi Sugai. (2007) First total synthesis of modiolide A, based on the whole-cell yeast-catalyzed asymmetric reduction of a propargyl ketone. Tetrahedron 63:36, pages 8752-8760.
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Chihiro Hiraoka, Masaaki Matsuda, Yuya Suzuki, Shigeo Fujieda, Mina Tomita, Ken-ichi Fuhshuku, Rika Obata, Shigeru Nishiyama & Takeshi Sugai. (2006) Screening, substrate specificity and stereoselectivity of yeast strains, which reduce sterically hindered isopropyl ketones. Tetrahedron: Asymmetry 17:24, pages 3358-3367.
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Masaki Nogawa, Satomi Sugawara, Rie Iizuka, Megumi Shimojo, Hiromichi Ohta, Minoru Hatanaka & Kazutsugu Matsumoto. (2006) Enantioselective microbial hydrolysis of dissymmetrical cyclic carbonates with disubstitution. Tetrahedron 62:51, pages 12071-12083.
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Toshikuni Tsujigami, Takeshi Sugai & Hiromichi Ohta. (2001) Microbial asymmetric reduction of α-hydroxyketones in the anti-Prelog selectivity. Tetrahedron: Asymmetry 12:18, pages 2543-2549.
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Takahiro Yamazaki, Atsuhito Kuboki, Hiromichi Ohta, Thomas M. Mitzel, Leo A. Paquette & Takeshi Sugai. (2010) ChemInform Abstract: Yamadazyma farinosa IFO 10896‐Mediated Reduction of 4,4‐Dimethoxy‐2‐butanone as the Key Step for the Preparation of 1,3‐Diols with Unsymmetrical Substituents.. ChemInform 31:47.
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Yamadazyma Farinosa IFO 10896-Mediated Reduction of 4,4-Dimethoxy-2-Butanone as the Key-Step for the Preparation of 1,3-Diols with Unsymmetrical Substituents

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Yamadazyma Farinosa IFO 10896-Mediated Reduction of 4,4-Dimethoxy-2-Butanone as the Key-Step for the Preparation of 1,3-Diols with Unsymmetrical Substituents

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