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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 36, 2006 - Issue 8
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Original Articles

Utility and Synthetic Uses of Mannich Reaction: An Efficient Route for Synthesis of Thiadiazino‐[1,3,5][3,2‐a]benzimidazoles

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Pages 987-996 | Received 01 Jun 2005, Published online: 16 Aug 2006

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Ahmed F. M. EL-Mahdy, Zeinab A. Hozien, Shimaa Abdelnaser, Ahmed A. K. Mohammed, Suliman M. El‐Sawaisi & Hassan A. H. El-Sherief. (2021) Studies on synthesis and reactions of some new five and six-membered heterocycles bearing 5,6,7,8-tetrahydrobenzo[b]thieno[2,3-d]pyrimidin-4(3H)-ones skeleton. Synthetic Communications 51:21, pages 3246-3260.
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Articles from other publishers (24)

Liang Jiao, Mengya Sun, Jie Yang, Weisheng Yang & Hongqi Dai. (2023) Cyclic synthesis of lignin anthraquinone electrolytes for aqueous redox flow batteries. International Journal of Biological Macromolecules 229, pages 236-246.
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Zeinab A. Hozien, Ahmed F. M. EL-Mahdy, Ahmad Abo Markeb, Laila S. A. Ali & Hassan A. H. El-Sherief. (2020) Synthesis of Schiff and Mannich bases of new s -triazole derivatives and their potential applications for removal of heavy metals from aqueous solution and as antimicrobial agents . RSC Advances 10:34, pages 20184-20194.
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Yanqiu Sui, Xiaofeng Li, Wei Chang, Hao Wan, Wei Li, Fan Yang & Zhong-Zhen Yu. (2020) Multi-responsive nanocomposite membranes of cellulose nanocrystals and poly(N-isopropyl acrylamide) with tunable chiral nematic structures. Carbohydrate Polymers 232, pages 115778.
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Bhawna Uprety & Charmaine Arderne. (2019) The crystal structure of the zwitterionic co-crystal of 2,4-dichloro-6-{[(3-hydroxypropyl)azaniumyl]methyl}phenolate and 2,4-dichlorophenol. Acta Crystallographica Section E Crystallographic Communications 75:10, pages 1452-1455.
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V. V. Dotsenko, K. A. Frolov, E. A. Chigorina, A. N. Khrustaleva, E. Yu. Bibik & S. G. Krivokolysko. (2019) New possibilities of the Mannich reaction in the synthesis of N-, S,N-, and Se,N-heterocycles. Russian Chemical Bulletin 68:4, pages 691-707.
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Ahmed F. M. EL-Mahdy, Hassan A. H. El-Sherief & Zainab A. Hozien. (2019) Convenient One-Pot Four-Component Synthesis of 6,8-Disubstituted-5,6,7,8-tetrahydropyrimido[4,5-d]pyrimidin-4(3H)-ones via a Triple Mannich Reaction. Australian Journal of Chemistry 72:7, pages 542.
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Ahmed F. M. EL-Mahdy & Hassan A. H. EL-Sherief. (2016) An efficient and rapid intramolecular cyclization of a quadruple Mannich reaction for one-pot synthesis of pentaazaphenalenes and their antimicrobial activities. RSC Advances 6:94, pages 92134-92143.
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Victor V. Dotsenko, Konstantin A. Frolov & Sergey G. Krivokolysko. (2015) Synthesis of partially hydrogenated 1,3,5-thiadiazines by Mannich reaction. Chemistry of Heterocyclic Compounds 51:2, pages 109-127.
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Victor V. Dotsenko, Konstantin A. Frolov, Tatyana M. Pekhtereva, Olena S. Papaianina, Sergey Yu. Suykov & Sergey G. Krivokolysko. (2014) Design and Synthesis of Pyrido[2,1- b ][1,3,5]thiadiazine Library via Uncatalyzed Mannich-Type Reaction . ACS Combinatorial Science 16:10, pages 543-550.
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SELVA GANESAN SUBRAMANIAPILLAI. (2013) Mannich reaction: A versatile and convenient approach to bioactive skeletons. Journal of Chemical Sciences 125:3, pages 467-482.
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V. V. Dotsenko, K. A. Frolov & S. G. Krivokolysko. (2012) Mannich reaction in the synthesis of N,S-containing heterocycles. 13*. One-pot method for preparing pyrimido[4,3-b]-[1,3,5]thiadiazines by reaction of aldehydes, cyanothioacetamide, formaldehyde, and primary amines. Chemistry of Heterocyclic Compounds 48:4, pages 642-649.
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V. V. Dotsenko, S. G. Krivokolysko & V. P. Litvinov. (2012) The Mannich reaction in the synthesis of N,S-containing heterocycles 11. Synthesis of 3,3′-(1,4-phenylene)-bis(8-aryl-6-oxo-3,4,7,8-tetrahydro-2H,6H-pyrido[2,1-b][1,3,5]thiadiazine-9-carbonitriles). Russian Chemical Bulletin 61:1, pages 131-135.
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Hassan A. H. El‐Sherief, Zeinab A. Hozien, Ahmed F. M. El‐Mahdy & Abdelwarth A. O. Sarhan. (2010) Intramolecular cyclization of Mannich reaction for synthesis of pyrimido[2,1‐b]‐1,3,5‐tiadiazines. Journal of Heterocyclic Chemistry 47:6, pages 1294-1302.
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Victor V. Dotsenko, Sergey G. Krivokolysko & Victor P. Litvinov. (2008) An efficient Mannich-type synthesis of bis(pyrido[2,1-b][1,3,5]thiadiazin-7-yl)-methanes. Monatshefte für Chemie - Chemical Monthly 139:6, pages 657-661.
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N. Shobana & P. Farid. 2008. Comprehensive Heterocyclic Chemistry III. Comprehensive Heterocyclic Chemistry III 457 521 .
V. V. Dotsenko, S. G. Krivokolysko & V. P. Litvinov. (2008) The Mannich reaction in the synthesis of N,S-containing heterocycles 8. Aminomethylation of 3,5-dicyano-6-oxo-1,4,5,6-tetrahydropyridine-2-thiolates as a method for the synthesis of new functionally substituted 3,7-diazabicyclo[3.3.1]nonane derivatives. Russian Chemical Bulletin 56:12, pages 2482-2486.
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V. V. Dotsenko, S. G. Krivokolysko & V. P. Litvinov. (2007) The Mannich reaction in the synthesis of N,S-containing heterocycles. 7. Effective one-pot synthesis of derivatives of spiro[3,5,7,11-tetraazatricyclo-[7.3.1.02,7]tridec-2-ene-13,4′-piperidine]. Chemistry of Heterocyclic Compounds 43:11, pages 1455-1459.
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V. V. Dotsenko, S. G. Krivokolysko, E. B. Rusanov & V. P. Litvinov. (2007) The Mannich reaction in the synthesis of N,S-containing heterocycles. Russian Chemical Bulletin 56:7, pages 1437-1440.
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V. V. Dotsenko, S. G. Krivokolysko, A. N. Chernega & V. P. Litvinov. (2007) The mannich reaction in the synthesis of N,S-containing heterocycles 4. Aminomethylation of 6-amino-3,5-dicyano-1,4-dihydropyridine-2-thiolates: A convenient regioselective route to 3,5,7,11-tetraazatricyclo[7.3.1.02,7]tridec-2-ene derivatives. Russian Chemical Bulletin 56:5, pages 1053-1062.
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Victor V. Dotsenko, Sergey G. Krivokolysko & Victor P. Litvinov. (2007) A Double Mannich-type Reaction in the 1,4,5,6-Tetrahydropyridine-2-thiolate Series: A Convenient Approach to Functionalized 3,7-Diazabicyclo[3.3.1]nonane Derivatives. Monatshefte für Chemie - Chemical Monthly 138:5, pages 489-494.
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V. V. Dotsenko, S. G. Krivokolysko & V. P. Litvinov. (2007) Synthesis of new derivatives of pyrido[1,2-a]triazine. Chemistry of Heterocyclic Compounds 43:4, pages 517-518.
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V. V. Dotsenko, S. G. Krivokolysko, V. P. Litvinov & E. B. Rusanov. (2007) Simple one-pot synthesis of 3,5,7,11-tetraazatricyclo[7.3.1.02,7]tridec-2-ene derivatives under Mannich reaction conditions. Doklady Chemistry 413:1, pages 68-71.
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Victor V. Dotsenko, Sergey G. Krivokolysko, Alexander N. Chernega & Victor P. Litvinov. (2006) An Efficient Mannich-Type One-Pot Synthesis of 3,5,7,11-Tetraazatricyclo [7.3.1.02,7]tridec-2-ene Derivatives Starting from Functionalized 1,4-Dihydropyridines. Monatshefte für Chemie - Chemical Monthly 138:1, pages 35-42.
Crossref
Abd El‐Wareth A. O. Sarhan, Shams H. Abdel‐Hafez, Hassan El‐Sherief & Tarek Aboel‐Fadl. (2006) Utility and Synthetic Uses of Mannich Reaction: An Efficient Route for Synthesis of Thiadiazino[1,3,5][3,2‐a]benzimidazoles.. ChemInform 37:35.
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