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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 36, 2006 - Issue 24
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Original Articles

Studies on Spiroheterocycles, Part II: Heterocyclization of the Spiro Compounds Containing Cyclohexanone and Thiobarbituric Acid with Different Bidentate Nucleophilic Reagents

Rajani Kanta Behera Department of Chemistry, Organic Synthesis Laboratory, Sambalpur University, Burla, Orissa, IndiaCorrespondence[email protected]
,
Ajay Kumar Behera Department of Chemistry, Organic Synthesis Laboratory, Sambalpur University, Burla, Orissa, India
,
Rosy Pradhan Department of Chemistry, Organic Synthesis Laboratory, Sambalpur University, Burla, Orissa, India
,
Anita Pati Department of Chemistry, Organic Synthesis Laboratory, Sambalpur University, Burla, Orissa, India
&
Manabendra Patra Department of Chemistry, Organic Synthesis Laboratory, Sambalpur University, Burla, Orissa, India
Pages 3729-3742 | Received 08 May 2006, Published online: 01 Dec 2006

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Poulomi Majumdar, Prajna Parimita Mohanta, Sankarshan Sahu & Ajaya Kumar Behera. (2018) Studies on the synthesis of spiroheterocycles and their derivatives using dimedone as synthetic precursor. Synthetic Communications 48:14, pages 1747-1754.
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Poulomi Majumdar, Prajna Parimita Mohanta, RajaniK. Behera & Ajaya Kumar Behera. (2013) Chemistry of Dimedone for Synthesis of Oxygen-, Nitrogen-, and Sulfur- Containing Heterocycles from 2-(3-Hydroxy-5,5-dimethylcyclohex-2-enylidene)malononitrile. Synthetic Communications 43:6, pages 899-914.
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RajaniK. Behera, AjayK. Behera, Rosy Pradhan, Anita Pati & Manabendra Patra. (2009) Studies on Spiroheterocycles, Part III: Synthesis of Diazaspiroundecanetetraone Derivatives Containing Biologically Active Heterocycles. Phosphorus, Sulfur, and Silicon and the Related Elements 184:3, pages 753-765.
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Articles from other publishers (30)

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Prashant Rai, Jyotsna Singh, Rohit Kumar, Srikrishna Saripella & Nageswara Rao Golakoti. (2022) Design, synthesis, in vitro, and in vivo anti-cancer evaluation of the novel spirobibenzopyrans on epithelial cancer model of Drosophila melanogaster. Chemical Papers 76:10, pages 6401-6413.
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B. N. Lakshminarayana, N. R. Sreenatha, A. S. Jeevan Chakravarthy, B. Suchithra & S. Hariprasad. (2022) Structural, Computational and 3D Interaction Energy Calculations of the Compound 2-chloro-3-(1-napthyl)-5,5-dimethyl-2-cyclohexenone. Crystallography Reports 67:2, pages 201-208.
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Zahra Jamshidi, Abbas Ali Esmaeili & Joel T. Mague. (2016) Efficient One-Pot Three-Component Synthesis of Novel Spiro(Indoline-3,7′-Thiazolo[3,2- a ]Pyrimidine) Derivatives . Journal of Chemical Research 40:8, pages 471-474.
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Deng-Feng Yue, Jian-Qiang Zhao, Zhen-Hua Wang, Xiao-Mei Zhang, Xiao-Ying Xu & Wei-Cheng Yuan. (2016) A Neber approach for the synthesis of spiro-fused 2H-azirine-pyrazolone. Organic & Biomolecular Chemistry 14:6, pages 1946-1949.
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MOHAMMAD SHAHIDUL ISLAM, ASSEM BARAKAT, ABDULLAH MOHAMMED AL-MAJID, SAIED M SOLIMAN, HAZEM A GHABBOUR & HOONG-KUN FUN. (2015) Crystal Structure of 7,11-bis(2,4-dichlorophenyl)-2,4-dimethyl-2,4- diazaspiro[5.5]undecane -1,3,5,9-tetraone and its computational studies. Journal of Chemical Sciences 127:11, pages 2039-2050.
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Ming-Qiang Zhou, Jian-Qiang Zhao, Yong You, Xiao-Ying Xu, Xiao-Mei Zhang & Wei-Cheng Yuan. (2015) DMAP-catalyzed Diels–Alder reaction of 3-hydroxy-2-pyrone and methyleneindolinones for the synthesis of spirocyclic oxindoles. Tetrahedron 71:23, pages 3903-3908.
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Mohammad Islam, Abdullah Al-Majid, Assem Barakat, Saied Soliman, Hazem Ghabbour, Ching Quah & Hoong-Kun Fun. (2015) Synthesis, Molecular Structure and Spectroscopic Investigations of Novel Fluorinated Spiro Heterocycles. Molecules 20:5, pages 8223-8241.
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Komal Aggarwal & Jitender M. Khurana. (2015) Synthesis, photophysical studies, solvatochromic analysis and TDDFT calculations of diazaspiro compounds. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 143, pages 288-297.
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Ming-Qiang Zhou, Jian Zuo, Bao-Dong Cui, Jian-Qiang Zhao, Yong You, Mei Bai, Yong-Zheng Chen, Xiao-Mei Zhang & Wei-Cheng Yuan. (2014) Organocatalytic asymmetric double Michael reaction of Nazarov reagents with alkylidene azlactones for the construction of spiro-fused cyclohexanone/5-oxazolone system. Tetrahedron 70:35, pages 5787-5793.
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Pradip Kumar Maji, Rafique Ul Islam & Sujit Kumar Bera. (2014) RECENT PROGRESS IN METAL ASSISTED MULTICOMPONENT SYNTHESES OF HETEROCYCLES. HETEROCYCLES 89:4, pages 869.
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Komal Aggarwal, Kanika Vij & Jitender M. Khurana. (2014) An efficient catalyst free synthesis of nitrogen containing spiro heterocycles via [5 + 1] double Michael addition reaction. RSC Advances 4:26, pages 13313.
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Animesh Mondal, Mike Brown & Chhanda Mukhopadhyay. (2014) Multicomponent, one-pot and expeditious synthesis of highly substituted new spiro[indolo-3,10′-indeno[1,2-b]quinolin]-2,4,11′-triones under micellar catalytic effect of CTAB in water. RSC Advances 4:69, pages 36890.
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I. N. Klochkova, A. A. Anis’kov, M. P. Shchekina, S. V. Chuvaikina & K. A. Andreev. (2013) Reaction of unsymmetrical α,β-unsaturated ketones with thiobarbituric acid. Russian Journal of Organic Chemistry 49:9, pages 1344-1347.
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Poulomi Majumdar, Anita Pati, Rajani K. Behera & Ajaya Kumar Behera. (2013) Para Substituted Benzaldehydes as Expedient Reagents for the Oxidative Aromatization of Hydroquinoline. Journal of Heterocyclic Chemistry 50:3, pages 703-712.
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Qiao Chen, Jinyan Liang, Shoulei Wang, Dong Wang & Rui Wang. (2013) An asymmetric approach toward chiral multicyclic spirooxindoles from isothiocyanato oxindoles and unsaturated pyrazolones by a chiral tertiary amine thiourea catalyst. Chemical Communications 49:16, pages 1657.
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Yan-Yan Han, Wen-Yong Han, Xue Hou, Xiao-Mei Zhang & Wei-Cheng Yuan. (2012) FeCl 3 -Catalyzed Stereoselective Construction of Spirooxindole Tetrahydroquinolines via Tandem 1,5-Hydride Transfer/Ring Closure . Organic Letters 14:16, pages 4054-4057.
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Sengodagounder Muthusamy & Thangaraju Karikalan. (2012) Diastereoselective synthesis of macrocycles incorporating the spiro-indolofurans and -indolodioxolanes. Tetrahedron 68:5, pages 1443-1451.
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Anita Pati, Snigdha Mohapatra & Rajani K. Behera. (2011) Synthesis of spiroheterocycles derived from benzo[ f ]chromanone . Journal of Heterocyclic Chemistry 48:6, pages 1234-1237.
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Morteza Bararjanian, Saeedeh Hosseinzadeh, Saeed Balalaie & Hamid Reza Bijanzadeh. (2011) Palladium catalyzed stereoselective synthesis of 3-(anilinoarylmethylene)-2-oxindoles as Hesperadin analogoues. Tetrahedron 67:14, pages 2644-2650.
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Tecla Gasperi, M. Antonietta Loreto, Antonella Migliorini & Claudia Ventura. (2011) Synthesis of Aziridine- and Oxirane-2-phosphonates Spiro-Fused with Oxindoles. European Journal of Organic Chemistry 2011:2, pages 385-391.
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Sarah Van der Jeught, Nils De Vos, Kurt Masschelein, Ion Ghiviriga & Christian V. Stevens. (2010) Kharasch-Type Cyclizations of 2-Substituted Indole Derivatives Surprisingly Lead to Spiroindoles. European Journal of Organic Chemistry 2010:28, pages 5444-5453.
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I. Ammetto, T. Gasperi, M. Antonietta Loreto, A. Migliorini, F. Palmarelli & P. Antonio Tardella. (2009) Synthesis of Functionalized Spiroaziridine-oxindoles from 3-Ylideneoxindoles: An Easy Route to 3-(Aminoalkyl)oxindoles. European Journal of Organic Chemistry 2009:35, pages 6189-6197.
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Andrew C. SilvanusStephen J. HeffernanDavid J. LiptrotGabriele Kociok-KöhnBenjamin I. AndrewsDavid R. Carbery. (2009) Stereoselective Double Friedel−Crafts Alkylation of Indoles with Divinyl Ketones. Organic Letters 11:5, pages 1175-1178.
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Valentin A. Chebanov, Sergey M. Desenko & Thomas W. Gurley. 2008. Azaheterocycles Based on α, β-Unsaturated Carbonyls. Azaheterocycles Based on α, β-Unsaturated Carbonyls 37 60 .
Rajani Kanta Behera, Ajay Kumar Behera, Rosy Pradhan, Anita Pati & Manabendra Patra. (2007) Studies on Spiroheterocycles. Part 2. Heterocyclization of the Spiro Compounds Containing Cyclohexanone and Thiobarbituric Acid with Different Bidentate Nucleophilic Reagents.. ChemInform 38:18.
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Jitender M. Khurana, Reema Arora & Sarishti Satija. (2007) 7,11-Diaryl-2,4-diazaspiro[5.5]undecane-1,5,9-triones: A New Series of Spiroheterocycles. HETEROCYCLES 71:12, pages 2709.
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