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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 38, 2008 - Issue 18
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Original Articles

Trichloroisocyanuric Acid–Mediated One-Pot Synthesis of Unsymmetrical 2,5-Disubstituted 1,3,4-Oxadiazoles at Ambient Temperature

D. M. Pore Department of Chemistry, Shivaji University, Kolhapur, IndiaCorrespondence[email protected]
,
S. M. Mahadik Department of Chemistry, Shivaji University, Kolhapur, India
&
U. V. Desai Department of Chemistry, Shivaji University, Kolhapur, India
Pages 3121-3128 | Received 16 Feb 2008, Published online: 09 Sep 2008

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KinjalD. Patel, ShraddhaM. Prajapati, ShyamaliN. Panchal & HiteshD. Patel. (2014) Review of Synthesis of 1,3,4-Oxadiazole Derivatives. Synthetic Communications 44:13, pages 1859-1875.
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SantoshP. Pardeshi, SachinS. Patil & VivekD. Bobade. (2010) N-Chlorosuccinimide/1,8-Diazabicyclo[5.4.0]undec-7-ene (DBU)–Mediated Synthesis of 2,5-Disubstituted 1,3,4-Oxadiazoles. Synthetic Communications 40:11, pages 1601-1606.
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Articles from other publishers (23)

Jaime Crispim-Neto & Marcio C.S. de Mattos. (2023) Tribromoisocyanuric acid as an alternative oxidant in the synthesis of 2-amino-1,3,4-oxadiazoles from 1-acylthiosemicarbazides. Tetrahedron Letters 121, pages 154494.
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Sunita Kumari, Rajnish Kumar, Avijit Mazumder, Salahuddin, Shivani Saxena, Divya Sharma & Sagar Joshi. (2022) A Comprehensive Review on Synthetic Approaches and Biological Activities of 1,3,4-oxadiazole. Mini-Reviews in Organic Chemistry 19:8, pages 906-919.
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Sunita Kumari, Rajnish Kumar, Avijit Mazumder, Salahuddin, Shivani Saxena, Divya Sharma, Sagar Joshi & Mohd. Mustaqeem Abdullah. (2022) Recent Updates on Synthetic Strategies and Biological Potential of 1,3,4- oxadiazole: Review. Letters in Organic Chemistry 19:9, pages 689-704.
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Poonam, Geetika Bhasin, Richa Srivastava & Ram Singh. (2021) Oxadiazoles: moiety to synthesis and utilize. Journal of the Iranian Chemical Society 19:3, pages 665-677.
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Fei Ma, Jie Li, Shuning Zhang, Yuang Gu, Tingting Tan, Wanting Chen, Shuyue Wang, Peixiang Ma, Hongtao Xu, Guang Yang & Richard A. Lerner. (2021) DNA‐Encoded Libraries: Hydrazide as a Pluripotent Precursor for On‐DNA Synthesis of Various Azole Derivatives. Chemistry – A European Journal 27:31, pages 8214-8220.
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Valentin Karabelyov, Magdalena Kondeva-Burdina & Violina T. Angelova. (2021) Synthetic approaches to unsymmetrical 2,5-disubstituted 1,3,4-oxadiazoles and their MAO-B inhibitory activity. A review. Bioorganic & Medicinal Chemistry 29, pages 115888.
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Lori Gonnet, Christiane André-Barrès, Brigitte Guidetti, Alain Chamayou, Christophe Menendez, Michel Baron, Rachel Calvet & Michel Baltas. (2020) Study of the Two Steps and One-Pot Two-Step Mechanochemical Synthesis of Annulated 1,2,4-Triazoles. ACS Sustainable Chemistry & Engineering 8:8, pages 3114-3125.
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Karuna Raman Paidi, Murali Krishna Kolli, Eeda Koti Reddy & Venkata Ramana Pedakotla. (2020) Sodium hypochlorite-mediated synthesis of 2,5-disubstituted 1,3,4-oxadiazoles from hydrazides and aldehydes. Chemistry of Heterocyclic Compounds 56:3, pages 371-376.
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Xiang Yu, Yafang Chen, Wude Yang & Xingji Zhou. (2020) Preparation and Acetylcholinesterase Inhibitory Activities of Pyridine-Based 1,3,4-Oxadiazole Derivatives. HETEROCYCLES 100:8, pages 1163.
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Yuvraj B. Bhujabal, Kamlesh S. Vadagaonkar & Anant R. Kapdi. (2019) Pd/PTABS: Catalyst for Efficient C−H (Hetero)Arylation of 1,3,4‐Oxadiazoles Using Bromo(Hetero)Arenes. Asian Journal of Organic Chemistry 8:2, pages 289-295.
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Pinhui Diao, Yanqin Ge, Wenpei zhang, Chen Xu, Nannan Zhang & Cheng Guo. (2018) Synthesis of 2,5-disubstituted 1,3,4-oxadiazoles by visible-light-mediated decarboxylation–cyclization of hydrazides and diketones. Tetrahedron Letters 59:8, pages 767-770.
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Naveen Polkam, Bhaskar Kummari, Parsharamulu Rayam, Umarani Brahma, Vegi Ganga Modi Naidu, Sridhar Balasubramanian & Jaya Shree Anireddy. (2017) Synthesis of 2,5‐Disubstituted‐1,3,4‐oxadiazole Derivatives and Their Evaluation as Anticancer and Antimycobacterial Agents. ChemistrySelect 2:20, pages 5492-5496.
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Qiang Li, Yi Tao, Dongfang Xu, Haobing Zhang & Liping Duan. (2014) One‐pot Synthesis of 2,5‐Disubstituted‐1,3,4‐oxadiazoles Based on the Reaction of N , N ‐Dimethyl Amides with Acid Hydrazides . Journal of the Chinese Chemical Society 61:6, pages 665-670.
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Jayavant D. Patil & Dattaprasad M. Pore. (2014) [C16MPy]AlCl3Br: an efficient novel ionic liquid for synthesis of novel 1,2,4-triazolidine-3-thiones in water. RSC Advances 4:28, pages 14314.
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Peng Gao & Yunyang Wei. (2013) Efficient Oxidative Cyclisation of Acid Hydrazides to 2,5-Disubstituted 1,3,4-Oxadiazoles Catalysed by Bu 4 NI with t- BuOOH as Oxidant . Journal of Chemical Research 37:8, pages 506-510.
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Zhenhua Shang, Jing Ha, Xiao Tao, Longpeng Xu, Qing Liu & Pan Wang. (2013) (PhIO) n Mediated Annulations of Aromatic Aldehyde N-Acylhydrazones for the Synthesis of 1,3,4-Oxadiazoles . Bulletin of the Korean Chemical Society 34:6, pages 1879-1882.
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Cledualdo Soares de Oliveira, Bruno Freitas Lira, José Maria Barbosa-Filho, Jorge Gonçalo Fernandez Lorenzo & Petrônio Filgueiras de Athayde-Filho. (2012) Synthetic Approaches and Pharmacological Activity of 1,3,4-Oxadiazoles: A Review of the Literature from 2000–2012. Molecules 17:9, pages 10192-10231.
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Abdul Rauf & Nida Nayyar FarshoriAbdul Rauf & Nida Nayyar Farshori. 2012. Microwave-Induced Synthesis of Aromatic Heterocycles. Microwave-Induced Synthesis of Aromatic Heterocycles 25 38 .
Behrooz Maleki, Hafezeh Salehabadi, Zeinalabedin Sepehr & Mina Kermanian. (2011) Solvent-free, one-pot synthesis of 2,4,6-triarylpyridines using trichloroisocyanuric acid or N-bromosuccinimide as a novel and neutral catalyst. Collection of Czechoslovak Chemical Communications 76:11, pages 1307-1315.
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Hojat Veisi & Ramin Ghorbani-Vaghei. (2010) Recent progress in the application of N-halo reagents in the synthesis of heterocyclic compounds. Tetrahedron 66:38, pages 7445-7463.
Crossref
Ai‐Fang Li, Yi‐Bin Ruan, Qian‐Qian Jiang, Wen‐Bin He & Yun‐Bao Jiang. (2010) Molecular Logic Gates and Switches Based on 1,3,4‐Oxadiazoles Triggered by Metal Ions. Chemistry – A European Journal 16:19, pages 5794-5802.
Crossref
D. M. Pore, S. M. Mahadik & U. V. Desai. (2009) ChemInform Abstract: Trichloroisocyanuric Acid Mediated One‐Pot Synthesis of Unsymmetrical 2,5‐Disubstituted 1,3,4‐Oxadiazoles at Ambient Temperature.. ChemInform 40:6.
Crossref
Gabriela F. Mendonça, Haryadylla C. Sindra, Leonardo S. de Almeida, Pierre M. Esteves & Marcio C.S. de Mattos. (2009) Trihaloisocyanuric acids as convenient reagents for regioselective halogenation of β-dicarbonyl compounds. Tetrahedron Letters 50:4, pages 473-475.
Crossref

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