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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 38, 2008 - Issue 16
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Original Articles

Direct Route to a New Class of Acrylamide Thioglycosides and Their Conversions to Pyrazole Derivatives

Galal H. Elgemeie Chemistry Department, Faculty of Science, Helwan University, Ain-Helwan, Cairo, EgyptCorrespondence[email protected]
,
Shahinaz H. Elsayed Chemistry Department, Faculty of Science, Helwan University, Ain-Helwan, Cairo, Egypt
&
Ashraf S. Hassan Chemistry Department, Faculty of Science, Helwan University, Ain-Helwan, Cairo, Egypt
Pages 2700-2706 | Received 22 Aug 2006, Published online: 25 Aug 2010

Citations (26)

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Mohammed A. Khedr, Wafaa A. Zaghary, Gihad E. Elsherif, Rasha A. Azzam & Galal H. Elgemeie. (2023) Purine analogs: synthesis, evaluation and molecular dynamics of pyrazolopyrimidines based benzothiazole as anticancer and antimicrobial CDK inhibitors. Nucleosides, Nucleotides & Nucleic Acids 42:1, pages 77-104.
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Mohammed A. Khedr, Wafaa A. Zaghary, Gihad E. Elsherif, Rasha A. Azzam & Galal H. Elgemeie. (2022) Purine analogues as potential CDK9 inhibitors: New pyrazolopyrimidines as anti-avian influenza virus. Nucleosides, Nucleotides & Nucleic Acids 41:7, pages 643-670.
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Shorouk S. Mukhtar, Ashraf S. Hassan, Nesrin M. Morsy, Taghrid S. Hafez, Fatma M. Saleh & Hamdi M. Hassaneen. (2021) Design, synthesis, molecular prediction and biological evaluation of pyrazole-azomethine conjugates as antimicrobial agents. Synthetic Communications 51:10, pages 1564-1580.
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Mamdouh A. Abu-Zaied & Galal H. Elgemeie. (2019) Novel synthesis of new pyrazole thioglycosides as pyrazomycin analogues. Nucleosides, Nucleotides & Nucleic Acids 38:5, pages 374-389.
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Amira EM Abdallah & Galal H Elgemeie. (2018) Design, synthesis, docking, and antimicrobial evaluation of some novel pyrazolo[1,5-a] pyrimidines and their corresponding cycloalkane ring-fused derivatives as purine analogs. Drug Design, Development and Therapy 12, pages 1785-1798.
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Ashraf S. Hassan, Gaber O. Moustafa, Ahmed A. Askar, Ahmed M. Naglah & Mohamed A. Al-Omar. (2018) Synthesis and antibacterial evaluation of fused pyrazoles and Schiff bases. Synthetic Communications 48:21, pages 2761-2772.
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Ashraf S. Hassan, Gaber O. Moustafa & Hanem M. Awad. (2017) Synthesis and in vitro anticancer activity of pyrazolo[1,5-a]pyrimidines and pyrazolo[3,4-d][1,2,3]triazines. Synthetic Communications 47:21, pages 1963-1972.
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Galal H. Elgemeie & Mamdouh A. Abu-Zaied. (2017) Heterocyclic thioglycosides in carbohydrate research: Synthesis of thiophene thioglycosides. Nucleosides, Nucleotides & Nucleic Acids 36:8, pages 511-519.
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Galal H. Elgemeie, Nahed M. Fathy, Ayman B. Farag & Sheikha A. Alkursani. (2017) Antimetabolites: Design, synthesis, and cytotoxic evaluation of novel dihydropyridine thioglycosides and pyridine thioglycosides. Nucleosides, Nucleotides & Nucleic Acids 36:5, pages 355-377.
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Galal Elgemeie, Mamdouh Abou-Zeid, Shahinaz Alsaid, Ali Hebishy & Hanaa Essa. (2015) Novel Nucleoside Analogues: First Synthesis of Pyridine-4-Thioglycosides and Their Cytotoxic Evaluation. Nucleosides, Nucleotides & Nucleic Acids 34:10, pages 659-673.
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Articles from other publishers (16)

Amira E. M. Abdallah & Galal H. Elgemeie. (2022) New Route to the Synthesis of Novel Pyrazolo[1,5-a]pyrimidines and Evaluation of their Antimicrobial Activity as RNA Polymerase Inhibitors. Medicinal Chemistry 18:9, pages 926-948.
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Nesrin Mahmoud Morsy & Ashraf Sayed Hassan. (2022) Synthesis, reactions, and applications of chalcones: A review. European Journal of Chemistry 13:2, pages 241-252.
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Matteo Lusardi, Chiara Rotolo, Marco Ponassi, Erika Iervasi, Camillo Rosano & Andrea Spallarossa. (2022) One‐Pot Synthesis and Antiproliferative Activity of Highly Functionalized Pyrazole Derivatives. ChemMedChem 17:5.
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Galal H. Elgemeie & Reham A. Mohamed-Ezzat. 2022. New Strategies Targeting Cancer Metabolism. New Strategies Targeting Cancer Metabolism 547 611 .
Ashraf S. Hassan, Gaber O. Moustafa, Hanem M. Awad, Eman S. Nossier & Mohamed F. Mady. (2021) Design, Synthesis, Anticancer Evaluation, Enzymatic Assays, and a Molecular Modeling Study of Novel Pyrazole–Indole Hybrids. ACS Omega 6:18, pages 12361-12374.
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Nesrin M. Morsy, Ashraf S. Hassan, Taghrid S. Hafez, Mohamed R. H. Mahran, Inass A. Sadawe & Abdul M. Gbaj. (2020) Synthesis, antitumor activity, enzyme assay, DNA binding and molecular docking of Bis-Schiff bases of pyrazoles. Journal of the Iranian Chemical Society 18:1, pages 47-59.
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Ali M. S. Hebishy, Hagar T. Salama & Galal H. Elgemeie. (2020) New Route to the Synthesis of Benzamide-Based 5-Aminopyrazoles and Their Fused Heterocycles Showing Remarkable Antiavian Influenza Virus Activity. ACS Omega 5:39, pages 25104-25112.
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Ashraf S. Hassan, Ahmed A. Askar, Ahmed M. Naglah, Abdulrahman A. Almehizia & Ahmed Ragab. (2020) Discovery of New Schiff Bases Tethered Pyrazole Moiety: Design, Synthesis, Biological Evaluation, and Molecular Docking Study as Dual Targeting DHFR/DNA Gyrase Inhibitors with Immunomodulatory Activity. Molecules 25:11, pages 2593.
Crossref
Ahmed M. Naglah, Ahmed A. Askar, Ashraf S. Hassan, Tamer K. Khatab, Mohamed A. Al-Omar & Mashooq A. Bhat. (2020) Biological Evaluation and Molecular Docking with In Silico Physicochemical, Pharmacokinetic and Toxicity Prediction of Pyrazolo[1,5-a]pyrimidines. Molecules 25:6, pages 1431.
Crossref
Ashraf Hassan, Ahmed Askar, Eman Nossier, Ahmed Naglah, Gaber Moustafa & Mohamed Al-Omar. (2019) Antibacterial Evaluation, In Silico Characters and Molecular Docking of Schiff Bases Derived from 5-aminopyrazoles. Molecules 24:17, pages 3130.
Crossref
Mohamed El-Naggar, Ashraf Hassan, Hanem Awad & Mohamed Mady. (2018) Design, Synthesis and Antitumor Evaluation of Novel Pyrazolopyrimidines and Pyrazoloquinazolines. Molecules 23:6, pages 1249.
Crossref
Ashraf S. Hassan, Hanem M. Awad, Asmaa A. Magd-El-Din & Taghrid S. Hafez. (2017) Synthesis and in vitro antitumor evaluation of novel Schiff bases. Medicinal Chemistry Research 27:3, pages 915-927.
Crossref
Vladimir D. Dyachenko, Ivan V. Dyachenko & Valentine G. Nenajdenko. (2018) Cyanothioacetamide: a polyfunctional reagent with broad synthetic utility. Russian Chemical Reviews 87:1, pages 1-27.
Crossref
Ashraf S. Hassan, Doaa M. Masoud, Farid M. Sroor & Ahmed A. Askar. (2017) Synthesis and biological evaluation of pyrazolo[1,5-a]pyrimidine-3-carboxamide as antimicrobial agents. Medicinal Chemistry Research 26:11, pages 2909-2919.
Crossref
Ashraf S. Hassan, Mohamed F. Mady, Hanem M. Awad & Taghrid S. Hafez. (2017) Synthesis and antitumor activity of some new pyrazolo[1,5- a ]pyrimidines. Chinese Chemical Letters 28:2, pages 388-393.
Crossref
Galal H. Elgemeie, Shahinaz H. Elsayed & Ashraf S. Hassan. (2009) ChemInform Abstract: Direct Route to a New Class of Acrylamide Thioglycosides (IV) and Their Conversions to Pyrazole Derivatives (V).. ChemInform 40:6.
Crossref

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