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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 39, 2009 - Issue 6
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Original Articles

Three-Component Synthesis of Pyrimidine and Pyrimidinone Derivatives in the Presence of High-Surface-Area MgO, a Highly Effective Heterogeneous Base Catalyst

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Pages 1055-1064 | Received 27 Aug 2008, Published online: 25 Feb 2009

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Read on this site (3)

IvangelaE. A. da Silva, VanildoM. L. Braga, MychelyS. Melo, Maria Tereza dosS. Correia & JanaínaV. dos Anjos. (2014) Simple, Multicomponent, Ecofriendly, Microwave-Mediated Route for the Synthesis of Antimicrobial 2-Amino-6-aryl-4-(3H)-pyrimidinones. Synthetic Communications 44:3, pages 374-380.
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Xian-Cao Yang, Hong Jiang & Wen Ye. (2012) Melamine as a Green and Reusable Catalyst for Knoevenagel Condensation at Room Temperature Under Solvent-Free Conditions. Synthetic Communications 42:3, pages 309-312.
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Min Lei, Lei Ma & Lihong Hu. (2011) Thiamine Hydrochloride–Catalyzed One-Pot Synthesis of 1,4-Dihydropyridine Derivatives Under Solvent-Free Conditions. Synthetic Communications 41:13, pages 1969-1976.
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Articles from other publishers (31)

Anindya S. Manna, Rajesh Nandi, Tanmoy Ghosh, Subhasis Pal, Rajjakfur Rahaman & Dilip K. Maiti. (2024) Organic Base-Promoted C–N- and C–O-Coupled Domino Cyclization Strategy: Syntheses of Oxazine-6-ones and 4-Pyrimidinols. The Journal of Organic Chemistry 89:8, pages 5650-5664.
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Gayatree Shinde & Jyotsna Thakur. (2023) Core-shell structured Fe3O4@MgO: magnetically recyclable nanocatalyst for one-pot synthesis of polyhydroquinoline derivatives under solvent-free conditions. Journal of Chemical Sciences 135:1.
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Yuqing Shen, Chaoping Yuan, Xianyi Zhu, Qin Chen, Shenjun Lu & Haibo Xie. (2021) Engineering cellulose into water soluble poly(protic ionic liquid) electrolytes in the DBU/CO 2 /DMSO solvent system as an organocatalyst for the Knoevenagel condensation reaction . Green Chemistry 23:24, pages 9922-9934.
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Imen Dakhlaoui, Sahel Vahdati, Emna Maalej, Fakher Chabchoub, Michael Wiese, Jose Marco-Contelles & lhassane Ismaili. (2021) Synthesis and biological assessment of new pyrimidopyrimidines as inhibitors of breast cancer resistance protein (ABCG2). Bioorganic Chemistry 116, pages 105326.
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Pravin Chavan, Sachin Bangale, Dattatraya Pansare, Rohini Shelke, Shivaji Jadhav, Shrikrushna Tupare, Dhanraj Kamble & Megha Rai. (2020) Synthesis of substituted pyrimidine using ZnFe 2 O 4 nanocatalyst via one pot multi‐component reaction ultrasonic irradiation . Journal of Heterocyclic Chemistry 57:9, pages 3326-3333.
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Seddigheh Mohammadi, Dadkhoda Ghazanfari & Zahed Karimi-Jaberi. (2020) An Efficient, Potassium Carbonate-Catalysed, Three-Component Reaction of Aldehydes, Malononitrile and Amidines Leading to Highly Functionalized Pyrimidines in Aqueous Media. Letters in Organic Chemistry 17:4, pages 281-286.
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Ghodsi M. Ziarani, Fatemeh Mohajer, Razieh Moradi & Parisa Mofatehnia. (2019) The Molecular Diversity Scope of Urazole in the Synthesis of Organic Compounds. Current Organic Synthesis 16:7, pages 953-967.
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Leila Khazdooz, Amin Zarei, Tahmineh Ahmadi, Hamidreza Aghaei, Laleh Golestanifar & Nafisehsadat Sheikhan. (2017) Highly efficient and environmentally benign method for the synthesis of tetrahydrobenzo[b]pyrans using Ca9.5Mg0.5(PO4)5.5(SiO4)0.5F1.5 as a new bio- and nanocatalyst with Brønsted base and Lewis acid properties. Research on Chemical Intermediates 44:1, pages 93-115.
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Mohammad Seifi & Hassan Sheibani. (2017) Studies on condensation of 1,3-dicarbonyls with malononitrile: Synthesis of 2-pyridinones. Arabian Journal of Chemistry 10, pages S2453-S2456.
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Ahmad Rabiei, Shahrzad AbdolmohammadiFaezeh Shafaei. (2017) A green approach for an efficient preparation of 2,4-diamino-6-aryl-5-pyrimidinecarbonitriles using a TiO 2 –SiO 2 nanocomposite catalyst under solvent-free conditions . Zeitschrift für Naturforschung B 72:4, pages 241-247.
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S.V. Patil, N.D. Gaikwad & V.D. Bobade. (2016) A simple and efficient synthesis of imidazolo[1,2-a]pyridines using MgO in aqueous medium. Arabian Journal of Chemistry 9, pages S1649-S1653.
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Reza Aryan, Hamid Beyzaei & Fatemeh Sadeghi. (2015) Facile Synthesis of Some Novel Tetrasubstituted 2,4‐Diaminopyrimidine Derivatives in Aqueous Glucose Solution as a Fully Green Medium and Promoter. Journal of Heterocyclic Chemistry 53:6, pages 1963-1969.
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Hamzeh Kiyani & Fatemeh Ghorbani. (2016) Expeditious green synthesis of 3,4-disubstituted isoxazole-5(4H)-ones catalyzed by nano-MgO. Research on Chemical Intermediates 42:9, pages 6831-6844.
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Swastika Singh, Mohammad Saquib, Mandavi Singh, Jyoti Tiwari, Fatima Tufail, Jaya Singh & Jagdamba Singh. (2016) A catalyst free, multicomponent-tandem, facile synthesis of pyrido[2,3-d]pyrimidines using glycerol as a recyclable promoting medium. New Journal of Chemistry 40:1, pages 63-67.
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Daniel Könning & Jörg Swatschek. 2015. Multicomponent Reactions. Multicomponent Reactions 416 495 .
Moahboobeh Zahedifar & Hassan Sheibani. (2013) Rapid three-component synthesis of pyrimidine and pyrimidinone derivatives in the presence of Bi(NO3)3·5H2O as a mild and highly efficient catalyst. Research on Chemical Intermediates 41:1, pages 105-111.
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Ali Pourjavadi, Seyed Hassan Hosseini & Shiva Sadat Amin. (2014) Novel high loaded magnetic nanocatalyst based on multi-layered coating of poly(1-vinylimidazole). Chemical Engineering Journal 247, pages 85-92.
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Mahmood Tajbakhsh, Maryam Farhang & Ali Asghar Hosseini. (2013) MgO nanoparticles as an efficient and reusable catalyst for aza-Michael reaction. Journal of the Iranian Chemical Society 11:3, pages 665-672.
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Shahnaz Rostamizadeh & Masoomeh Nojavan. (2013) An Environmentally Benign Multicomponent Synthesis of Some Novel 2‐Methylthio Pyrimidine Derivatives Using MCM‐41‐NH 2 as Nanoreactor and Nanocatalyst . Journal of Heterocyclic Chemistry 51:2, pages 418-422.
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Abdollah Fallah-Shojaei, Khalil Tabatabaeian, Farhad Shirini & Seyyedeh Zoha Hejazi. (2014) Multi-walled carbon nanotube supported Fe3O4NPs: an efficient and reusable catalyst for the one-pot synthesis of 4H-pyran derivatives. RSC Advances 4:19, pages 9509.
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Davood Azarifar, Razieh Nejat-Yami & Mohammad Ali Zolfigol. (2013) 1,4-Diazabicyclo[2.2.2]octane-Catalyzed One-Pot Synthesis of Pyrazolo[1,2- a ][1,2,4]triazole-1,3-diones under Ultrasound Acceleration . Journal of Heterocyclic Chemistry 50:6, pages 1386-1390.
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Ali Pourjavadi, Seyed Hassan Hosseini & Zahra Sadat Emami. (2013) Cross-linked basic nanogel; robust heterogeneous organocalayst. Chemical Engineering Journal 232, pages 453-457.
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H. Sheibani & M. Babaie. (2014) Three-component synthesis of 4-amino-2-aryl-2H-pyrimido-[1,2-b][1,3]benzazole-3-carbonitriles and 4H-pyrimido-[2,1-b][1,3]benzazoles in the presence of magnesium oxide and 12-tungstophosphoric acid as catalysts. Russian Chemical Bulletin 62:10, pages 2202-2208.
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Ashok V. Borhade, Dipak R. Tope & Dattaprasad R. Patil. (2012) Nanocrystalline 5 % Fe/ZnO as an efficient catalyst for quinoxaline synthesis. Research on Chemical Intermediates 39:3, pages 1373-1383.
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Ali Pourjavadi, Seyed Hassan Hosseini, Seyyed Alireza AghayeeMeibody & Seyedeh Talieh Hosseini. (2013) Poly(basic ionic liquid) coated magnetic nanoparticles: High-loaded supported basic ionic liquid catalyst. Comptes Rendus. Chimie 16:10, pages 906-911.
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Mohammad Seifi, Mahboobeh K. Rabori & Hassan Sheibani. (2013) Highly Efficient Method for Synthesis of N-Amino-2-Pyridone Derivatives in the Presence of Catalysts such as Magnesium Oxide (MgO) and Bismuth(III) Nitrate Pentahydrate (Bi(NO<sub>3</sub>)<sub>3</sub>&#183;5H<sub>2</sub>O). Modern Research in Catalysis 02:02, pages 8-12.
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I. R. Siddiqui, Pragati Rai, Rahila, Anushree Srivastava, Arjita Srivastava & Anjali Srivastava. (2013) Synthesis of fused pyridines in the presence of thiamine hydrochloride as an efficient and reusable catalyst in aqueous conditions. New Journal of Chemistry 37:11, pages 3798.
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Hassan Sheibani & Fahimeh Hassani. (2011) Chemoselective synthesis of 4‐oxo‐2‐aryl‐4,10‐dihydropyrimido [1,2‐ a ][1,3]benzimidazol‐3‐yl cyanides via [3+3] atom combination of 2‐aminobenzimidazole with ethyl‐α‐cyanocinnamoates . Journal of Heterocyclic Chemistry 48:4, pages 915-920.
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Maryam Babaie & Hassan Sheibani. (2011) Nanosized magnesium oxide as a highly effective heterogeneous base catalyst for the rapid synthesis of pyranopyrazoles via a tandem four-component reaction. Arabian Journal of Chemistry 4:2, pages 159-162.
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Hassan Sheibani, Mohammad Seifi & Ayoob Bazgir. (2009) ChemInform Abstract: Three‐Component Synthesis of Pyrimidine and Pyrimidinone Derivatives in the Presence of High‐Surface‐Area MgO, a Highly Effective Heterogeneous Base Catalyst.. ChemInform 40:33.
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Fatemeh Mohajer. (2021) The Synthesis of SBA-15-Pr-3AP@Pd and its Application as a Highly Dynamic, Eco-Friendly Heterogeneous Catalyst for Suzuki-Miyaura Cross-Coupling Reaction. SSRN Electronic Journal.
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