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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 40, 2009 - Issue 1
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Original Articles

Triton B–Assisted, Efficient, and Convenient Synthesis of 3-Indolyl-3-hydroxy Oxindoles in Aqueous Medium

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Pages 39-45 | Received 07 Jan 2009, Published online: 09 Dec 2009

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HarshadasM. Meshram, PramodB. Thakur, MadhuB. Bejjam & VikasM. Bangade. (2013) DMF mediated Henry reaction of isatins: an efficient synthesis of 3-hydroxy-2-oxindole. Green Chemistry Letters and Reviews 6:1, pages 19-43.
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Articles from other publishers (22)

Gurpreet Kaur, Rajat Kumar, Shivam Saroch, Vivek Kumar Gupta & Bubun Banerjee. (2021) Mandelic Acid: An Efficient Organo-catalyst for the Synthesis of 3-substituted-3- Hydroxy-indolin-2-ones and Related Derivatives in Aqueous Ethanol at Room Temperature. Current Organocatalysis 8:1, pages 147-159.
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Mina Tavakolian & Mona Hosseini-Sarvari. (2020) Visible-light mediated, catalyst-free synthesis of 3-indolyl-3-hydroxy oxindoles in water. Sustainable Chemistry and Pharmacy 18, pages 100343.
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Banoth Paplal, Kota Sathish, Sakkani Nagaraju & Dhurke Kashinath. (2020) Synthesis of 3-ethynyl-3-hydroxy-2-oxindoles and 3-hydroxy-3-(indol-3-yl) indolin-2-ones using CuWO4 nanoparticles as recyclable heterogeneous catalyst in aqueous medium. Catalysis Communications 135, pages 105874.
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Eric Walker, Joshua Kammeraad, Jonathan Goetz, Michael T. Robo, Ambuj Tewari & Paul M. Zimmerman. (2019) Learning To Predict Reaction Conditions: Relationships between Solvent, Molecular Structure, and Catalyst. Journal of Chemical Information and Modeling 59:9, pages 3645-3654.
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Kiran S. Dalal, Yogesh B. Wagh, Yogesh A. Tayade, Dipak S. Dalal & Bhushan L. Chaudhari. (2018) Hen Egg White Lysozyme Catalyzed Efficient Synthesis of 3-Indolyl-3-hydroxy Oxindole in Aqueous Ethanol. Catalysis Letters 148:11, pages 3335-3341.
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Jun Tong, Yu-Wei Li & Da-Zhen Xu. (2017) Solvent-Controlled Friedel-Crafts Reaction for the Synthesis of 3-Indolyl-3-hydroxy Oxindoles and 3, 3-Diindolyl Oxindoles Catalyzed by Dabco-Base Ionic Liquids. ChemistrySelect 2:13, pages 3799-3803.
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Jun Tong, Lu-Shan Huang & Da-Zhen Xu. (2017) An efficient Friedel–Crafts alkylation for the synthesis of 3-indolyl-3-hydroxy oxindoles and unsymmetrical 3,3-diaryl oxindoles catalyzed by Dabco-based ionic liquids in water. New Journal of Chemistry 41:10, pages 3966-3974.
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Madhu Babu Bejjam, G. Santhosh Kumar, A. Swetha & H. M. Meshram. (2016) DABCO-catalyzed consecutive one pot four-component protocol for the synthesis of a novel class of (Z)-5-(3-hydroxy-2-oxoindolin-3-yl)-2-iminothiazolidin-4-ones. RSC Advances 6:17, pages 13820-13828.
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A. Sanjeeva Kumar, Palakuri Ramesh, G. Santosh Kumar, A. Swetha, Jagadeesh Babu Nanubolu & H. M. Meshram. (2016) A Ru( iii ) – catalyzed α-cross-coupling aldol type addition reaction of activated olefins with isatins . RSC Advances 6:3, pages 1705-1709.
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A. Sanjeeva Kumar, Palakuri Ramesh, G. Santosh Kumar, Jagadeesh Babu Nanubolu, T. Prabhakar Rao & H. M. Meshram. (2015) Indium/Fe( iii ) – mediated regioselective β-cross-coupling aldol type addition reaction of activated alkenes with isatins/isatinimines in aqueous media . RSC Advances 5:64, pages 51581-51585.
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Yogesh A. Tayade, Dipak R. Patil, Yogesh B. Wagh, Asha D. Jangle & Dipak S. Dalal. (2015) An efficient synthesis of 3-indolyl-3-hydroxy oxindoles and 3,3-di(indolyl)indolin-2-ones catalyzed by sulfonated β-CD as a supramolecular catalyst in water. Tetrahedron Letters 56:5, pages 666-673.
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Parvathaneni Sai Prathima, Pamanji Rajesh, Janapala Venkateswara Rao, Uppalapati Sai Kailash, Balasubramanian Sridhar & Mandapati Mohan Rao. (2014) “On water” expedient synthesis of 3-indolyl-3-hydroxy oxindole derivatives and their anticancer activity in vitro. European Journal of Medicinal Chemistry 84, pages 155-159.
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A. Swetha, G. Santosh Kumar, A. Sanjeeva Kumar & H.M. Meshram. (2014) FeCl3-catalyzed efficient synthesis of di(5-methylfuran/thiophen-2-yl)isatin analogues. Tetrahedron Letters 55:34, pages 4705-4710.
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Pramod B. Thakur, K. Sirisha, A.V.S. Sarma & Harshadas M. Meshram. (2014) Microwave assisted rapid, catalyst-free, and efficient synthesis of a new class of diversely functionalized 3-hydroxy-2-oxindole scaffolds under aqueous reaction media. Tetrahedron Letters 55:15, pages 2459-2462.
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Pramod B. Thakur & Harshadas M. Meshram. (2014) “On water” highly atom economical and rapid synthesis of a novel class of 3-hydroxy-2-oxindole scaffolds under a catalyst-free and column chromatography-free protocol at room temperature. RSC Advances 4:12, pages 6019.
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Pramod B. Thakur & Harshadas M. Meshram. (2014) ?On water? catalyst-free, column chromatography-free and atom economical protocol for highly diastereoselective synthesis of novel class of 3-substituted, 3-hydroxy-2-oxindole scaffolds at room temperature. RSC Advances 4:11, pages 5343.
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G. Santosh Kumar, Palakuri Ramesh, A. Sanjeeva Kumar, A. Swetha & H.M. Meshram. (2013) Catalyst-free synthesis of 3-hydroxy-3-(alkyl/aryl)indolin-2-ones by addition of organoaluminum reagents to isatins. Tetrahedron Letters 54:37, pages 5048-5051.
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Pramod Bhagwan Thakur, Katukuri Sirisha, Akella Venkata Subrahmanya Sarma, Jagadeesh Babu Nanubolu & Harshadas Mitaram Meshram. (2013) Highly regioselective and metal-free ?-addition of ?-keto esters to isatins, catalyzed by DABCO: direct access to novel class of diversely functionalized 3-hydroxy-2-oxindole scaffolds. Tetrahedron 69:31, pages 6415-6423.
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Pramod B. Thakur, Jagadeesh Babu Nanubolu & H.M. Meshram. (2013) WITHDRAWN: DABCO promoted unprecedented γ-addition of β-keto sulfones to isatins: regioselective synthesis of a novel class of diversely functionalized 3-hydroxy-2-oxindole scaffolds. Tetrahedron Letters.
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Mona Hosseini-Sarvari & Mina Tavakolian. (2012) Preparation, characterization, and catalysis application of nano-rods zinc oxide in the synthesis of 3-indolyl-3-hydroxy oxindoles in water. Applied Catalysis A: General 441-442, pages 65-71.
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H.M. Meshram, Palakuri Ramesh, A. Sanjeeva Kumar & A. Swetha. (2011) An efficient and environmentally friendly DABCO catalyzed Henry reaction of isatins. Tetrahedron Letters 52:44, pages 5862-5864.
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H. M. Meshram, D. Aravind Kumar, P. Ramesh Goud & B. Chennakesava Reddy. (2010) ChemInform Abstract: Triton B Assisted, Efficient, and Convenient Synthesis of 3‐Indolyl‐3‐hydroxy Oxindoles in Aqueous Medium. ChemInform 41:25.
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