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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 40, 2010 - Issue 11
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Original Articles

N-Chlorosuccinimide/1,8-Diazabicyclo[5.4.0]undec-7-ene (DBU)–Mediated Synthesis of 2,5-Disubstituted 1,3,4-Oxadiazoles

Santosh P. Pardeshi Department of Chemistry, Hansraj Pragji Thakersi (HPT) Arts and Raojisa Yamasa Kshatriya (RYK) Science College, Nasik, India
,
Sachin S. Patil Department of Chemistry, Hansraj Pragji Thakersi (HPT) Arts and Raojisa Yamasa Kshatriya (RYK) Science College, Nasik, India
&
Vivek D. Bobade Department of Chemistry, Hansraj Pragji Thakersi (HPT) Arts and Raojisa Yamasa Kshatriya (RYK) Science College, Nasik, IndiaCorrespondence[email protected]
Pages 1601-1606 | Received 12 Mar 2009, Published online: 06 May 2010

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Ana Flávia Borsoi, Mateus Emanuel Coldeira, Kenia Pissinate, Fernanda Souza Macchi, Luiz Augusto Basso, Diógenes Santiago Santos & Pablo Machado. (2017) Ultrasound-assisted synthesis of 2-amino-1,3,4-oxadiazoles through NBS-mediated oxidative cyclization of semicarbazones. Synthetic Communications 47:14, pages 1319-1325.
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KinjalD. Patel, ShraddhaM. Prajapati, ShyamaliN. Panchal & HiteshD. Patel. (2014) Review of Synthesis of 1,3,4-Oxadiazole Derivatives. Synthetic Communications 44:13, pages 1859-1875.
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Articles from other publishers (17)

Jian Wang, Linyang Wang, Huilin Qin, Ruotong Tian & Yuliang Pan. (2023) Green oxidative cyclization to access 2,5-disubstituted-1,3,4-oxadiazoles from aldehydes and hydrazide derivatives using FeBr3 catalyst and hydrogen peroxide. Tetrahedron Letters 131, pages 154783.
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Jaime Crispim-Neto & Marcio C.S. de Mattos. (2023) Tribromoisocyanuric acid as an alternative oxidant in the synthesis of 2-amino-1,3,4-oxadiazoles from 1-acylthiosemicarbazides. Tetrahedron Letters 121, pages 154494.
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Sunita Kumari, Rajnish Kumar, Avijit Mazumder, Salahuddin, Shivani Saxena, Divya Sharma & Sagar Joshi. (2022) A Comprehensive Review on Synthetic Approaches and Biological Activities of 1,3,4-oxadiazole. Mini-Reviews in Organic Chemistry 19:8, pages 906-919.
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Sunita Kumari, Rajnish Kumar, Avijit Mazumder, Salahuddin, Shivani Saxena, Divya Sharma, Sagar Joshi & Mohd. Mustaqeem Abdullah. (2022) Recent Updates on Synthetic Strategies and Biological Potential of 1,3,4- oxadiazole: Review. Letters in Organic Chemistry 19:9, pages 689-704.
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Poonam, Geetika Bhasin, Richa Srivastava & Ram Singh. (2021) Oxadiazoles: moiety to synthesis and utilize. Journal of the Iranian Chemical Society 19:3, pages 665-677.
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Kian Donnelly & Marcus Baumann. (2022) Flow synthesis of oxadiazoles coupled with sequential in-line extraction and chromatography. Beilstein Journal of Organic Chemistry 18, pages 232-239.
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Fei Ma, Jie Li, Shuning Zhang, Yuang Gu, Tingting Tan, Wanting Chen, Shuyue Wang, Peixiang Ma, Hongtao Xu, Guang Yang & Richard A. Lerner. (2021) DNA‐Encoded Libraries: Hydrazide as a Pluripotent Precursor for On‐DNA Synthesis of Various Azole Derivatives. Chemistry – A European Journal 27:31, pages 8214-8220.
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Valentin Karabelyov, Magdalena Kondeva-Burdina & Violina T. Angelova. (2021) Synthetic approaches to unsymmetrical 2,5-disubstituted 1,3,4-oxadiazoles and their MAO-B inhibitory activity. A review. Bioorganic & Medicinal Chemistry 29, pages 115888.
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Barbara Wołek, Mateusz Werłos, Magdalena Komander & Agnieszka Kudelko. (2020) Efficient Synthesis of Novel 1,3,4-Oxadiazoles Bearing a 4-N,N-Dimethylaminoquinazoline Scaffold via Palladium-Catalyzed Suzuki Cross-Coupling Reactions. Molecules 25:21, pages 5150.
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Jihye Baek, Eun-kyung Je, Jina Kim, Ai Qi, Kwang-Hyun Ahn & Yongho Kim. (2020) Experimental and Theoretical Studies on the Mechanism of DDQ-Mediated Oxidative Cyclization of N -Aroylhydrazones . The Journal of Organic Chemistry 85:15, pages 9727-9736.
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Faryal Chaudhry, Munawar Ali Munawar & Misbahul Ain Khan. (2020) Facile Synthesis of Isoniazid Derivatives – 1-[2-(3-Aryl(Hetaryl)-1-Phenyl-1H-Pyrazol-4-yl)-5-(Pyridin-4-yl)-1,3,4-Oxadiazol-3(2H)-yl]Ethanones. Chemistry of Heterocyclic Compounds 56:5, pages 615-618.
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Jagdeep Grover, Nirav Bhatt, Vivek Kumar, Neeraj K. Patel, Bhagirath J. Gondaliya, M. Elizabeth Sobhia, Kamlesh K. Bhutani & Sanjay M. Jachak. (2015) 2,5-Diaryl-1,3,4-oxadiazoles as selective COX-2 inhibitors and anti-inflammatory agents. RSC Advances 5:56, pages 45535-45544.
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Santosh P. Pardeshi, Sachin S. Patil, Amar A. Patil & Vivek D. Bobade. (2012) A facile route for the synthesis of vinyl-substituted 1,3,4-oxadiazoles. Research on Chemical Intermediates 39:7, pages 3399-3405.
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Peng Gao & Yunyang Wei. (2013) Efficient Oxidative Cyclisation of Acid Hydrazides to 2,5-Disubstituted 1,3,4-Oxadiazoles Catalysed by Bu 4 NI with t- BuOOH as Oxidant . Journal of Chemical Research 37:8, pages 506-510.
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Zhenhua Shang, Jing Ha, Xiao Tao, Longpeng Xu, Qing Liu & Pan Wang. (2013) (PhIO) n Mediated Annulations of Aromatic Aldehyde N-Acylhydrazones for the Synthesis of 1,3,4-Oxadiazoles . Bulletin of the Korean Chemical Society 34:6, pages 1879-1882.
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Cledualdo Soares de Oliveira, Bruno Freitas Lira, José Maria Barbosa-Filho, Jorge Gonçalo Fernandez Lorenzo & Petrônio Filgueiras de Athayde-Filho. (2012) Synthetic Approaches and Pharmacological Activity of 1,3,4-Oxadiazoles: A Review of the Literature from 2000–2012. Molecules 17:9, pages 10192-10231.
Crossref
Santosh P. Pardeshi, Sachin S. Patil & Vivek D. Bobade. (2010) ChemInform Abstract: N‐Chlorosuccinimide/1,8‐Diazabicyclo[5.4.0]undec‐7‐ene (DBU)‐Mediated Synthesis of 2,5‐Disubstituted 1,3,4‐Oxadiazoles.. ChemInform 41:43.
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