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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 44, 2014 - Issue 7
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Original Articles

Solvent-Free Synthesis of Dihydropyridines and Acridinediones via a Salicylic Acid–Catalyzed Hantzsch Multicomponent Reaction

Imène Amine Khodja Laboratoire de Synthèse des Molécules d'Intérêts Biologiques, Département de Chimie, Faculté des Sciences Exactes, Université de Constantine, Constantine, Algéria
,
Wassima Ghalem Laboratoire de Synthèse des Molécules d'Intérêts Biologiques, Département de Chimie, Faculté des Sciences Exactes, Université de Constantine, Constantine, Algéria
,
Zineb Imene Dehimat Laboratoire de Synthèse des Molécules d'Intérêts Biologiques, Département de Chimie, Faculté des Sciences Exactes, Université de Constantine, Constantine, Algéria
,
Raouf Boulcina Laboratoire de Synthèse des Molécules d'Intérêts Biologiques, Département de Chimie, Faculté des Sciences Exactes, Université de Constantine, Constantine, Algéria
,
Bertrand Carboni Sciences Chimiques de Rennes, UMR 6226 CNRS-Université de Rennes 1, Campus de Beaulieu, Rennes, France
&
Abdelmadjid Debache Laboratoire de Synthèse des Molécules d'Intérêts Biologiques, Département de Chimie, Faculté des Sciences Exactes, Université de Constantine, Constantine, AlgériaCorrespondence[email protected]
Pages 959-967 | Received 12 Jul 2013, Published online: 24 Feb 2014

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Priyanka Kalal, Nusrat Sahiba, Ayushi Sethiya, Pankaj Teli, Deepkumar Joshi & Shikha Agarwal. (2023) Facile One Pot Synthesis of Acridinediones Using Caffeine Hydrogen Sulfate Catalyst and Their Antimicrobial Evaluation. Polycyclic Aromatic Compounds 43:9, pages 7930-7941.
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Rima Laroum, Raouf Boulcina, Chawki Bensouici & Abdelmadjid Debache. (2019) Facile Synthesis and Antioxidant Evaluation of 4-Arylmethylideneisoxazol-5(4H)-ones. Organic Preparations and Procedures International 51:6, pages 583-588.
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Yuliang Zhang & Zhongqiang Zhou. (2018) Solvent-Free One-Pot Synthesis of 1,8-Dioxo-Decahydroacridines by a [Et3NH][HSO4] Catalyzed Multicomponent Reaction. Polycyclic Aromatic Compounds 38:4, pages 329-337.
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Imène Sehout, Raouf Boulcina, Boudjemaa Boumoud, Taous Boumoud & Abdelmadjid Debache. (2017) Solvent-free synthesis of polyhydroquinoline and 1,8-dioxodecahydroacridine derivatives through the Hantzsch reaction catalyzed by a natural organic acid: A green method. Synthetic Communications 47:12, pages 1185-1191.
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Articles from other publishers (22)

Phat Ngoc Nguyen, Gia-Linh Ngoc Nguyen, The-Anh Trinh Duong, Mai-Phuong Thi Le, Linh Phi Nguyen, Jinsoo Kim, Phuong Hoang Tran, Huynh-Hoa Thi Truong & Hai Truong Nguyen. (2024) High-yield, fast, and green synthesis of acridine derivatives using a Co/C catalyst from rice husks with a microwave-assisted method. Reaction Chemistry & Engineering.
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Naghmeh Farzaneh, Fateme Radinekiyan, Mohammad Reza Naimi-Jamal & Mohammad G. Dekamin. (2023) Development of new magnetic nanocomposite designed by reduced graphene oxide aerogel and HKUST-1, and its catalytic application in the synthesis of polyhydroquinoline and 1,8-dioxo-decahydroacridine derivatives. Scientific Reports 13:1.
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Fatemeh Moghadaskhou, Reza Eivazzadeh-Keihan, Zahra Sadat, Azadeh Tadjarodi & Ali Maleki. (2023) Fabrication and characterization of a novel catalyst based on modified zirconium metal-organic-framework for synthesis of polyhydroquinolines. Scientific Reports 13:1.
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Aline de Fátima Silva Lago, Danilo Forti Carvalho de Benedicto, Larissa da Silva & Sérgio Scherrer Thomasi. (2023) 1,4-Dihydropyridine Derivatives: An Overview of Synthesis Conditions and Biological Tests. Current Organic Chemistry 27:18, pages 1567-1610.
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Chunping Dong, Yumei Wang, Shiyu Chen, Yue Zhang, Cheli Wang, Jian Li & Yongsheng Zhou. (2023) 4,6‐Dihydroxysalicylic Acid‐Catalyzed Oxidative Olefination of Methyl N ‐Heteroarenes with Benzyl Amines . European Journal of Organic Chemistry 26:29.
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Mohammad Ali Ghasemzadeh, Boshra Mirhosseini-Eshkevari & Jaber Dadashi. (2023) An efficient protocol for the synthesis of pyridines and hydroquinolones using IRMOF-3/GO/CuFe2O4 composite as a magnetically separable heterogeneous catalyst. Scientific Reports 13:1.
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Padinjare Veetil Saranya, Mohan Neetha, C.M.A. Afsina & Gopinathan Anilkumar. (2022) An Overview of Ruthenium-Catalyzed Multicomponent Reactions. Current Organic Chemistry 26:12, pages 1119-1148.
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Dharminder Sharma, Manish Kumar, Sandeep Kumar, Amartya Basu, Dhananjay Bhattacherjee, Abha Chaudhary & Pralay Das. (2022) Application of Cyclohexane‐1,3‐diones in the Synthesis of Six‐Membered Nitrogen‐Containing Heterocycles. ChemistrySelect 7:12.
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Kioumars Aghapoor, Farshid Mohsenzadeh, Hossein Reza Darabi & Hani Sayahi. (2021) Crystalline salicylic acid as an efficient catalyst for ultrafast Paal–Knorr pyrrole synthesis under microwave induction. Journal of Chemical Sciences 133:2.
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Nusrat Sahiba, Ayushi Sethiya, Jay Soni & Shikha Agarwal. (2021) Acridine‐1,8‐diones: Synthesis and Biological Applications. ChemistrySelect 6:9, pages 2210-2251.
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Amna M. Abdella, Amr M. Abdelmoniem, Ismail A. Abdelhamid & Ahmed H. M. Elwahy. (2020) Synthesis of heterocyclic compounds via Michael and Hantzsch reactions. Journal of Heterocyclic Chemistry 57:4, pages 1476-1523.
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Somayeh Asgharnasl, Reza Eivazzadeh-Keihan, Fateme Radinekiyan & Ali Maleki. (2020) Preparation of a novel magnetic bionanocomposite based on factionalized chitosan by creatine and its application in the synthesis of polyhydroquinoline, 1,4-dyhdropyridine and 1,8-dioxo-decahydroacridine derivatives. International Journal of Biological Macromolecules 144, pages 29-46.
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Prasun Choudhury, Pranab Ghosh & Basudeb Basu. (2019) Amine-functionalized graphene oxide nanosheets (AFGONs): an efficient bifunctional catalyst for selective formation of 1,4-dihydropyridines, acridinediones and polyhydroquinolines. Molecular Diversity 24:1, pages 283-294.
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Mehtab Parveen, Afroz Aslam, Ajaz Ahmad, Mahboob Alam, Manuela Ramos Silva & P.S. Pereira Silva. (2020) A facile & convenient route for the stereoselective synthesis of Z- isoxazol-5(4H)-ones derivatives catalysed by sodium acetate: Synthesis, multispectroscopic properties, crystal structure with DFT calculations, DNA-binding studies and molecular docking studies. Journal of Molecular Structure 1200, pages 127067.
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Majid Heravi & Vahideh Zadsirjan. 2020. Recent Advances in Applications of Name Reactions in Multicomponent Reactions. Recent Advances in Applications of Name Reactions in Multicomponent Reactions 15 138 .
Asiyeh Mosallanezhad & Hamzeh Kiyani. (2019) Green Synthesis of 3-Substituted-4-arylmethylideneisoxazol-5(4H)-one Derivatives Catalyzed by Salicylic Acid. Current Organocatalysis 6:1, pages 28-35.
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Kobra Nikoofar & Fatemeh Molaei Yielzoleh. (2018) A concise study on dimedone: A versatile molecule in multi-component reactions, an outlook to the green reaction media. Journal of Saudi Chemical Society 22:6, pages 715-741.
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Larry Yet. 2018. Privileged Structures in Drug Discovery. Privileged Structures in Drug Discovery 59 82 .
Shi-Jun Yü, Si Wu, Xin-Min Zhao & Cheng-Wei Lü. (2016) Green and efficient synthesis of acridine-1,8-diones and hexahydroquinolines via a KH2PO4 catalyzed Hantzsch-type reaction in aqueous ethanol. Research on Chemical Intermediates 43:5, pages 3121-3130.
Crossref
Jan Ježek, Jan Hlaváček & Jaroslav ŠebestíkJan Ježek, Jan Hlaváček & Jaroslav Šebestík. 2017. Biomedical Applications of Acridines. Biomedical Applications of Acridines 9 45 .
Imene Amine Khodja, Wassima Ghalem, Zineb Imene Dehimat, Raouf Boulcina, Bertrand Carboni & Abdelmadjid Debache. (2014) ChemInform Abstract: Solvent‐Free Synthesis of Dihydropyridines and Acridinediones via a Salicylic Acid‐Catalyzed Hantzsch Multicomponent Reaction.. ChemInform 45:33.
Crossref
Mohammad Ali Ghasemzadeh, Boshra Mirhosseini-Eshkevari & Jaber Dadashi. (2022) Irmof-3/Go/Cufe2o4 Nanostructure: A Reusable and Efficient Nanocatalyst for the Preparation of Substituted Pyridines and Hydroquinolones. SSRN Electronic Journal.
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