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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 48, 2018 - Issue 9
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Original Articles

Green procedure for highly efficient, rapid synthesis of imidazo[1,2-a]pyridine and its late stage functionalization

Prasanjit GhoshDepartment of Chemistry, University of North Bengal, Darjeeling, West Bengal, IndiaView further author information
,
Bhaskar GangulyDepartment of Chemistry, University of North Bengal, Darjeeling, West Bengal, IndiaView further author information
,
Barnali KarDepartment of Chemistry, University of North Bengal, Darjeeling, West Bengal, IndiaView further author information
,
Seema DwivediDepartment of Chemistry, University of North Bengal, Darjeeling, West Bengal, IndiaView further author information
&
Sajal DasDepartment of Chemistry, University of North Bengal, Darjeeling, West Bengal, IndiaCorrespondence[email protected]
View further author information
Pages 1076-1084 | Received 07 Dec 2017, Published online: 26 Mar 2018

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Jin Wha Park, Yong Hwan Kim & Dae Young Kim. (2020) Electrochemical oxidative iodination of imidazo[1,2-a]pyridines using NaI as iodine source. Synthetic Communications 50:5, pages 710-718.
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Annah Gupta, Sonakshi Sasan, Avneet Kour, Nargis Nelofar, Dilip Manikrao Mondhe & Kamal K. Kapoor. (2019) Triarylimidazo[1,2-a]pyridine-8-carbonitriles: solvent-free synthesis and their anti-cancer evaluation. Synthetic Communications 49:14, pages 1813-1822.
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Articles from other publishers (27)

Keval Bhatt, Dhara Patel, Mrudangsinh Rathod, Ashish Patel & Drashti Shah. (2024) Efficient synthesis and characterization of imidazo[1,2‐ a ]pyridine‐8‐carboxamide derivatives: A promising scaffold for drug development . Vietnam Journal of Chemistry.
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Juanjuan Gao, Xiaohua Guo, Zhaowen Liu & Yifan Cao. (2024) HFIP-promoted synthesis of imidazo [1,2-a]pyridines containing CF3-substituted tertiary alcohols at room temperature. Tetrahedron 156, pages 133943.
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Kingkar Ghosh, Surendra Nath Barman, Prasun Choudhury & Kinkar Biswas. (2024) Amberlyst® A‐26(OH) Ion Exchange Resin Catalyzed Synthesis of Imidazo[1,2 a ] pyridines/thiazoles in Water and their Further Functionalization . ChemistrySelect 9:9.
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Swati Chauhan, Pratibha VermaVandana Srivastava. (2024) Ultrasound-Mediated Green Synthesis of Imidazo[1,2-a]pyridines and Imidazo[2,1-b]thiazoles through C(sp3)–H Functionalization. Synlett.
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Zhaowen Liu, Xiaohua Guo, Zhixi Chen, Longhui Wu & Kai Yang. (2024) Metal-Free Synthesis of Trifluoromethyl Carbinol-Containing Imidazo[1,2-a]pyridines via Dehydrative Coupling of Imidazo[1,2-a]pyridines with Trifluoroacetaldehyde. Synthesis.
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Keval Bhatt, Dhara Patel, Mrudangsinh Rathod, Ashish Patel & Drashti Shah. (2023) Efficient Synthesis and Characterization of 6-substituted-N-p-tolyl-imidazo[1,2- a]pyridine-8-carboxamide: A Promising Scaffold for Drug Development. Current Organic Chemistry 27:22, pages 1978-1984.
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Juanjuan Gao, Zhaowen Liu, Xiaohua Guo, Longhui Wu, Zhixi Chen & Kai Yang. (2023) 1,1,1,3,3,3-Hexafluoro-2-Propanol-Promoted Friedel–Crafts Reaction: Metal-Free Synthesis of C3-Difluoromethyl Carbinol-Containing Imidazo[1,2-a]pyridines at Room Temperature. Molecules 28:22, pages 7522.
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Keval Bhatt, Dhara Patel, Mrudangsinh Rathod, Ashish Patel & Drashti Shah. (2023) An Update on the Recent Green Synthetic Approaches for Imidazo[1,2-a] Pyridine: A Privileged Scaffold. Current Organic Chemistry 26:22, pages 2016-2054.
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Bilgesu Onur Sucu. (2022) Biological evaluation of imidazopyridine derivatives as potential anticancer agents against breast cancer cells. Medicinal Chemistry Research 31:12, pages 2231-2242.
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Jaspreet Kour, Pratiksha Khajuria, Alpa Sharma & Sanghapal D. Sawant. (2022) TBAX/Oxone‐Mediated Halogenation of Pyrazoles and Other Heterocycles: An Entry to Important Cross‐Coupling Reactions. Chemistry – An Asian Journal 17:22.
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Kousar Jahan, Firdoos Ahmad Sofi, Sumi Aisha Salim & Prasad V. Bharatam. (2022) NIS mediated dehydrogenative-cyclocondensation in aqueous medium towards the synthesis of 2-arylimidazo[1,2-a]pyridines and their 3-formylated derivatives. Tetrahedron 112, pages 132715.
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Jasmine Panda, Bishnu P. Raiguru, Mitali Mishra, Seetaram Mohapatra & Sabita Nayak. (2022) Recent Advances in the Synthesis of Imidazo[1,2‐ a ]pyridines: A Brief Review . ChemistrySelect 7:3.
Crossref
Vanya Kurteva. (2021) Recent Progress in Metal-Free Direct Synthesis of Imidazo[1,2- a ]pyridines . ACS Omega 6:51, pages 35173-35185.
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Davinder Singh, Javeed Ahmad Tali, Gulshan Kumar & Ravi Shankar. (2021) Metal-free oxidative decarbonylative halogenation of fused imidazoles. New Journal of Chemistry 45:44, pages 20551-20555.
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Saideh Rajai-Daryasarei, Mohammad Hossein Gohari & Narges Mohammadi. (2021) Reactions involving aryl methyl ketone and molecular iodine: a powerful tool in the one-pot synthesis of heterocycles. New Journal of Chemistry 45:44, pages 20486-20518.
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Partha Pratim Sen, Vishal Jyoti Roy & Sudipta Raha Roy. (2021) Metal-free regioselective bromination of imidazo-heteroarenes: the dual role of an organic bromide salt in electrocatalysis. Green Chemistry 23:15, pages 5687-5695.
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Saradhi Kalari, Sridhar Balasubramanian & Haridas B. Rode. (2021) Difluorinative-hydroxylation and C-3 functionalization (halogenation/SCN/NO) of imidazopyridine using Selectfluor as fluorine source or oxidant respectively. Tetrahedron Letters 71, pages 153028.
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Frederik Rostrup, Christina B. Falk-Petersen, Kasper Harpsøe, Stine Buchleithner, Irene Conforti, Sascha Jung, David E. Gloriam, Tanja Schirmeister, Petrine Wellendorph & Bente Frølund. (2021) Structural Determinants for the Mode of Action of Imidazopyridine DS2 at δ-Containing γ-Aminobutyric Acid Type A Receptors. Journal of Medicinal Chemistry 64:8, pages 4730-4743.
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Meenakshi Budhiraja, Rajesh Kondabala, Amjad Ali & Vikas Tyagi. (2020) First biocatalytic Groebke-Blackburn-Bienaymé reaction to synthesize imidazo[1,2-a]pyridine derivatives using lipase enzyme. Tetrahedron 76:47, pages 131643.
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Dharmendra Das, Zigmee T. Bhutia, Padmini C. Panjikar, Amrita Chatterjee & Mainak Banerjee. (2020) A simple and efficient route to 2‐arylimidazo[1,2‐a]pyridines and zolimidine using automated grindstone chemistry. Journal of Heterocyclic Chemistry 57:11, pages 4099-4107.
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Zigmee T. Bhutia, Padmini C. Panjikar, Shruti Iyer, Amrita Chatterjee & Mainak Banerjee. (2020) Iodine Promoted Efficient Synthesis of 2-Arylimidazo[1,2- a ]pyridines in Aqueous Media: A Comparative Study between Micellar Catalysis and an “On-Water” Platform . ACS Omega 5:22, pages 13333-13343.
Crossref
José S. S. Neto, Renata A. Balaguez, Marcelo S. Franco, Victor C. de Sá Machado, Sumbal Saba, Jamal Rafique, Fábio Z. Galetto & Antonio L. Braga. (2020) Trihaloisocyanuric acids in ethanol: an eco-friendly system for the regioselective halogenation of imidazo-heteroarenes. Green Chemistry 22:11, pages 3410-3415.
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Larry Yet. 2020. 431 464 .
Larry Yet. 2020. 325 361 .
Chada Raji Reddy & Amarender Goud Burra. (2019) [4 + 2]-Annulation of MBH-Acetates of Acetylenic Aldehydes with Imidazoles/Benzimidazoles To Access Imidazo[1,2- a ]pyridines/Benzimidazo[1,2- a ]pyridines . The Journal of Organic Chemistry 84:14, pages 9169-9178.
Crossref
Irwan Iskandar Roslan, Kian-Hong Ng, Stephan Jaenicke & Gaik-Khuan Chuah. (2019) Photocatalytic regeneration of brominating agent in the visible light-mediated synthesis of imidazo[1,2- a ]pyridines . Catalysis Science & Technology 9:6, pages 1528-1534.
Crossref
Rashmi Semwal, Chitrakar Ravi, Rahul Kumar, Ramavatar Meena & Subbarayappa Adimurthy. (2018) Sodium Salts (NaI/NaBr/NaCl) for the Halogenation of Imidazo-Fused Heterocycles. The Journal of Organic Chemistry 84:2, pages 792-805.
Crossref

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