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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 48, 2018 - Issue 21
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Articles

Synthesis and antibacterial evaluation of fused pyrazoles and Schiff bases

Ashraf S. HassanOrganometallic and Organometalloid Chemistry Department, National Research Centre, Cairo, Egypt; Correspondence[email protected]
ORCID Iconhttp://orcid.org/0000-0002-4771-716XView further author information
ORCID Icon,
Gaber O. MoustafaPeptide Chemistry Department, National Research Centre, Cairo, Egypt; View further author information
,
Ahmed A. AskarBotany and Microbiology Department Faculty of Science (Boys), Al-Azhar University, Cairo, Egypt; View further author information
,
Ahmed M. NaglahDrug Exploration and Development Chair (DEDC) Department of Pharmaceutical Chemistry College of Pharmacy, King Saud University, Riyadh, Saudi ArabiaView further author information
&
Mohamed A. Al-OmarDrug Exploration and Development Chair (DEDC) Department of Pharmaceutical Chemistry College of Pharmacy, King Saud University, Riyadh, Saudi ArabiaView further author information
Pages 2761-2772 | Received 01 Jun 2018, Published online: 18 Oct 2018

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Y. Shyma Mary, Yohannan Sheena Mary, Renjith Thomas & B. Narayana. (2022) Detailed Study of Three Halogenated Benzylpyrazole Acetamide Compounds with Potential Anticancer Properties. Polycyclic Aromatic Compounds 42:9, pages 6705-6719.
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Mohammad A Alam. (2022) Antibacterial Pyrazoles: Tackling Resistant Bacteria. Future Medicinal Chemistry 14:5, pages 343-362.
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Ahmed M Naglah, Gaber O Moustafa, Ahmed A Elhenawy, Marwa M Mounier, Heba El-Sayed, Mohamed A Al-Omar, Abdulrahman A Almehizia & Mashooq A Bhat. (2021) Nα-1, 3-Benzenedicarbonyl-Bis-(Amino Acid) and Dipeptide Candidates: Synthesis, Cytotoxic, Antimicrobial and Molecular Docking Investigation. Drug Design, Development and Therapy 15, pages 1315-1332.
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Shorouk S. Mukhtar, Ashraf S. Hassan, Nesrin M. Morsy, Taghrid S. Hafez, Fatma M. Saleh & Hamdi M. Hassaneen. (2021) Design, synthesis, molecular prediction and biological evaluation of pyrazole-azomethine conjugates as antimicrobial agents. Synthetic Communications 51:10, pages 1564-1580.
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Amit A. Pund, Shweta S. Saboo, Gajanan M. Sonawane, Amol C. Dukale & Baban K. Magare. (2020) Synthesis of 2,5-disubstituted-1,3,4-thiadiazole derivatives from (2S)-3-(benzyloxy)-2-[(tert-butoxycarbonyl) amino] propanoic acid and evaluation of anti-microbial activity. Synthetic Communications 50:24, pages 3854-3864.
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Asmaa F. Kassem, Gaber O. Moustafa, Eman S. Nossier, Hemat S. Khalaf, Marwa M. Mounier, Suliman A. Al-Yousef & Sabry Y. Mahmoud. (2019) In vitro anticancer potentiality and molecular modelling study of novel amino acid derivatives based on N1,N3-bis-(1-hydrazinyl-1-oxopropan-2-yl) isophthalamide. Journal of Enzyme Inhibition and Medicinal Chemistry 34:1, pages 1247-1258.
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Articles from other publishers (26)

Yasemin Ünver, Fatih Çelik, Ali Aydın, Nevin Süleymanoğlu, Reşat Ustabaş, Halil İbrahim Güler & Kadriye İnan Bektaş. (2024) New 1,2,4-triazol-3-one derivatives with 4-fluorobenzene: Synthesis, characterization, DFT, antimicrobial-antiproliferative activities and molecular docking study. Journal of Molecular Structure 1305, pages 137806.
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Abdulrahman A. Almehizia, Wael M. Aboulthana, Ahmed M. Naglah & Ashraf S. Hassan. (2024) In vitro biological studies and computational prediction-based analyses of pyrazolo[1,5- a ]pyrimidine derivatives . RSC Advances 14:12, pages 8397-8408.
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Ekta Lathwal, Sanjeev Kumar, Pranab Kumar Sahoo, Sushmita Ghosh, Sutapa Mahata, Vilas D. Nasare, Ravikumar Kapavarapu & Suresh Kumar. (2024) Pyrazole-based and N,N-diethylcarbamate functionalized some novel aurone analogs: Design, synthesis, cytotoxic evaluation, docking and SAR studies, against AGS cancer cell line. Heliyon 10:5, pages e26843.
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Zahra Elyasi, Javad Safaei Ghomi, Gholam Reza Najafi & Mahboubeh A. Sharif. (2023) Fabrication of uniform Pd nanoparticles immobilized on crosslinked ionic chitosan support as a super-active catalyst toward regioselective synthesis of pyrazole-fused heterocycles. International Journal of Biological Macromolecules 253, pages 126589.
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Asmaa Kamal Mourad, Fatehia K. Mohammed, Abd El‐Naby Ibrahim Essawy, Ahmed Yousef Soliman & Samar Magdy Sayed. (2023) Pyrazolo[3,4‐ d ]pyrimidine‐based scaffolds as antibacterial agents: Synthetic strategies, reactions, and in vitro biological evaluation . Journal of Heterocyclic Chemistry 60:7, pages 1150-1164.
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Ashraf S. Hassan, Nesrin M. Morsy, Wael M. Aboulthana & Ahmed Ragab. (2022) In vitro enzymatic evaluation of some pyrazolo[1,5‐ a ]pyrimidine derivatives: Design, synthesis, antioxidant, anti‐diabetic, anti‐Alzheimer, and anti‐arthritic activities with molecular modeling simulation . Drug Development Research 84:1, pages 3-24.
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Ghulam Mustafa, Muhammad Zia-ur-Rehman, Sajjad Hussain Sumrra, Muhammad Ashfaq, Wardha Zafar & Maryam Ashfaq. (2022) A critical review on recent trends on pharmacological applications of pyrazolone endowed derivatives. Journal of Molecular Structure 1262, pages 133044.
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Remya R.S.. (2022) Design, Synthesis and Pharmacological Evaluation of Novel Benzimidazole Derivatives as Anticancer Agents. Current Bioactive Compounds 18:6.
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Nesrin Mahmoud Morsy & Ashraf Sayed Hassan. (2022) Synthesis, reactions, and applications of chalcones: A review. European Journal of Chemistry 13:2, pages 241-252.
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C. Liu. (2022) Anion Induced Synthesis and Crystal Structures of Schiff Base Copper(II) and Zinc(II) Complexes with Antibacterial Activity. Russian Journal of Coordination Chemistry 48:6, pages 385-396.
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Ratnamala S. Bendre, Rahul D. Patil, Pramod N. Patil, Harun M. Patel & Rakesh S. Sancheti. (2022) Synthesis and characterization of new Schiff-bases as Methicillin resistant Staphylococcus aureus (MRSA) inhibitors. Journal of Molecular Structure 1252, pages 132152.
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Ashraf S. Hassan, Nesrin M. Morsy, Hassan M. Awad & Ahmed Ragab. (2021) Synthesis, molecular docking, and in silico ADME prediction of some fused pyrazolo[1,5-a]pyrimidine and pyrazole derivatives as potential antimicrobial agents. Journal of the Iranian Chemical Society 19:2, pages 521-545.
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Mabrouk Horchani, Hayet Edziri, Abdel Halim Harrath, Hichem Ben Jannet & Anis Romdhane. (2022) Access to new Schiff bases tethered with pyrazolopyrimidinone as antibacterial agents: Design and synthesis, molecular docking and DFT analysis. Journal of Molecular Structure 1248, pages 131523.
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Y. Lakshmi Prapurna & Chada Raji Reddy. 2022. Comprehensive Heterocyclic Chemistry IV. Comprehensive Heterocyclic Chemistry IV 1 28 .
David Barker & Lisa Pilkington. 2022. Comprehensive Heterocyclic Chemistry IV. Comprehensive Heterocyclic Chemistry IV 565 585 .
Nicolai Wippert, Martin Nieger, Claudine Herlan, Nicole Jung & Stefan Bräse. (2021) Synthesis of new pyrazolo[1,2,3]triazines by cyclative cleavage of pyrazolyltriazenes. Beilstein Journal of Organic Chemistry 17, pages 2773-2780.
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Ashraf S. Hassan, Gaber O. Moustafa, Hanem M. Awad, Eman S. Nossier & Mohamed F. Mady. (2021) Design, Synthesis, Anticancer Evaluation, Enzymatic Assays, and a Molecular Modeling Study of Novel Pyrazole–Indole Hybrids. ACS Omega 6:18, pages 12361-12374.
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Nesrin M. Morsy, Ashraf S. Hassan, Taghrid S. Hafez, Mohamed R. H. Mahran, Inass A. Sadawe & Abdul M. Gbaj. (2020) Synthesis, antitumor activity, enzyme assay, DNA binding and molecular docking of Bis-Schiff bases of pyrazoles. Journal of the Iranian Chemical Society 18:1, pages 47-59.
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Samir Bondock, Salwa Alqahtani & Ahmed M. Fouda. (2020) Synthesis and anticancer evaluation of some new pyrazolo[3,4‐ d ][1,2,3]triazin‐4‐ones, pyrazolo[1,5‐ a ]pyrimidines, and imidazo[1,2‐ b ]pyrazoles clubbed with carbazole . Journal of Heterocyclic Chemistry 58:1, pages 56-73.
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Hemat S. Khalaf, Ahmed M. Naglah, Mohamed A. Al-Omar, Gaber O. Moustafa, Hassan M. Awad & Ahmed H. Bakheit. (2020) Synthesis, Docking, Computational Studies, and Antimicrobial Evaluations of New Dipeptide Derivatives Based on Nicotinoylglycylglycine Hydrazide. Molecules 25:16, pages 3589.
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Ashraf S. Hassan, Ahmed A. Askar, Ahmed M. Naglah, Abdulrahman A. Almehizia & Ahmed Ragab. (2020) Discovery of New Schiff Bases Tethered Pyrazole Moiety: Design, Synthesis, Biological Evaluation, and Molecular Docking Study as Dual Targeting DHFR/DNA Gyrase Inhibitors with Immunomodulatory Activity. Molecules 25:11, pages 2593.
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Ahmed M. Naglah, Ahmed A. Askar, Ashraf S. Hassan, Tamer K. Khatab, Mohamed A. Al-Omar & Mashooq A. Bhat. (2020) Biological Evaluation and Molecular Docking with In Silico Physicochemical, Pharmacokinetic and Toxicity Prediction of Pyrazolo[1,5-a]pyrimidines. Molecules 25:6, pages 1431.
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Mohamed A. Salem, Ahmed Ragab, Ahmed A. Askar, Abeer El-Khalafawy & Abeer H. Makhlouf. (2020) One-pot synthesis and molecular docking of some new spiropyranindol-2-one derivatives as immunomodulatory agents and in vitro antimicrobial potential with DNA gyrase inhibitor. European Journal of Medicinal Chemistry 188, pages 111977.
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Marie-Aude Hiebel & Franck Suzenet. 2020. 505 531 .
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Ashraf Hassan, Ahmed Askar, Eman Nossier, Ahmed Naglah, Gaber Moustafa & Mohamed Al-Omar. (2019) Antibacterial Evaluation, In Silico Characters and Molecular Docking of Schiff Bases Derived from 5-aminopyrazoles. Molecules 24:17, pages 3130.
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