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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 49, 2019 - Issue 11
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Articles

Synthesis of novel bis(chromenes) and bis(chromeno[3,4-C]pyridine) incorporating piperazine moiety

Ahmed E. M. MekkyChemistry Department, Faculty of Science, Cairo University, Giza, EgyptORCID Iconhttp://orcid.org/0000-0002-8226-010X
ORCID Icon &
Sherif M. H. SanadChemistry Department, Faculty of Science, Cairo University, Giza, EgyptCorrespondence[email protected]
ORCID Iconhttp://orcid.org/0000-0002-0186-6418
ORCID Icon
Pages 1385-1395 | Received 07 Feb 2019, Published online: 22 Apr 2019

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Ahmed E. M. Mekky & Sherif M. H. Sanad. (2022) Microwave-assisted synthesis of nicotinonitrile and/or arene-linked bis(chromene-thiazoles) as new VRE and MRSA inhibitors. Synthetic Communications 52:24, pages 2276-2290.
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Ahmed A. M. Ahmed, Ahmed E. M. Mekky & Sherif M. H. Sanad. (2022) New piperazine-based bis(thieno[2,3-b]pyridine) and bis(pyrazolo[3,4-b]pyridine) hybrids linked to benzofuran units: Synthesis and in vitro screening of potential acetylcholinesterase inhibitors. Synthetic Communications 52:6, pages 912-925.
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Ahmed E. M. Mekky & Sherif M. H. Sanad. (2021) Synthesis, Characterization, and Antimicrobial Evaluation of Novel Thiohydrazonates and Pyrazolo[3,4-b]pyridines . Polycyclic Aromatic Compounds 41:5, pages 936-949.
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Ahmed E. M. Mekky, Mohamed S. Mohamed Ahmed, Sherif M. H. Sanad & Zeinab A. Abdallah. (2021) Bis(benzofuran-enaminone) hybrid possessing piperazine linker: Versatile precursor for microwave assisted synthesis of bis(pyrido[2',3':3,4]pyrazolo[1,5-a]pyrimidines). Synthetic Communications 51:7, pages 1085-1099.
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Sherif M. H. Sanad & Ahmed E. M. Mekky. (2021) Efficient synthesis and characterization of novel bis(chromenes) and bis(benzo[f]chromenes) linked to thiazole units. Synthetic Communications 51:4, pages 611-624.
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Ahmed E. M. Mekky, Sherif M. H. Sanad, Ahmed Y. Said & Mohamed A. A. Elneairy. (2020) Synthesis, cytotoxicity, in-vitro antibacterial screening and in-silico study of novel thieno[2,3-b]pyridines as potential pim-1 inhibitors. Synthetic Communications 50:15, pages 2376-2389.
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Sherif M. H. Sanad & Ahmed E. M. Mekky. (2020) Synthesis, in-vitro antibacterial and anticancer screening of novel nicotinonitrile-coumarin hybrids utilizing piperazine citrate. Synthetic Communications 50:10, pages 1468-1485.
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Ahmed A. M. Ahmed, Ahmed E. M. Mekky, Ahmed H. M. Elwahy & Sherif M. H. Sanad. (2020) Facile synthesis and characterization of novel benzo-fused macrocyclic dicarbonitriles and pyrazolo-fused macrocycles containing thiazole subunits. Synthetic Communications 50:6, pages 796-804.
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Articles from other publishers (21)

H. Kh. Thabet, Mohd Imran, Mohd ImranSaleh AlaqlM. H. M. Helal. (2024) Bis(2-cyanoacetamide) in Heterocyclic Synthesis: Synthesis of Some Bis[2-oxopyridine, 2-iminochromene, Chromeno[3,4-c]pyridine, Benzochromeno[3,4-c]pyridine] Derivatives. Oriental Journal Of Chemistry 40:1, pages 65-73.
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Goncagül Serdaroğlu, Nesimi Uludag & Elvan Üstün. (2023) Efficient synthesis of chromeno[2,3-b]pyridine derivatives using Zn(OTf)2 as a catalyst: DFT computations, molecular docking and ADME studies. Journal of Molecular Liquids 375, pages 121364.
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Zeinab A. Abdallah, Sherif M. H. Sanad, Ahmed E. M. Mekky & Mohamed S. Mohamed Ahmed. (2023) New Arylazo‐Based (Chromene‐Thiazole) Hybrids as Potential MRSA Inhibitors. Chemistry & Biodiversity 20:4.
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Ahmed E. M. Mekky & Sherif M. H. Sanad. (2023) [3+2] Cycloaddition Synthesis of New Piperazine‐Linked Bis(chromene) Hybrids Possessing Pyrazole Units as Potential Acetylcholinesterase Inhibitors. Chemistry & Biodiversity 20:4.
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Ismail A. Abdelhamid, Mohamed R. Shaaban & Ahmed H.M. Elwahy. 2023. 135 200 .
Sherif M. H. Sanad & Ahmed E. M. Mekky. (2022) Ultrasound‐Mediated Synthesis of New (Piperazine‐Chromene)‐Linked Bis(thieno[2,3‐ b ]pyridine) Hybrids as Potential Anti‐acetylcholinesterase . ChemistrySelect 7:41.
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Mohamed S. Mohamed Ahmed, Ahmed E.M. Mekky & Sherif M.H. Sanad. (2022) Regioselective [3 + 2] cycloaddition synthesis and theoretical calculations of new chromene-pyrazole hybrids: A DFT-based Parr Function, Fukui Function, local reactivity indexes, and MEP analysis. Journal of Molecular Structure 1267, pages 133583.
Crossref
Sherif M. H. Sanad, Ahmed E. M. Mekky & Ahmed A. M. Ahmed. (2022) Tandem synthesis, cytotoxicity, and in silico study of new 1,3,4‐oxadiazoles as potential thymidylate synthase inhibitors. Archiv der Pharmazie 355:10.
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Rohit Pal, Md. Jawaid Akhtar, Khadga Raj, Shamsher Singh, Priyanka Sharma, Sourav Kalra, Pooja A. Chawla & Bhupinder Kumar. (2022) Design, synthesis and evaluation of piperazine clubbed 1,2,4-triazine derivatives as potent anticonvulsant agents. Journal of Molecular Structure 1257, pages 132587.
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Sherif M.H. Sanad, Ahmed E.M. Mekky & Tamer T. El-Idreesy. (2022) Potential bacterial biofilm, MRSA, and DHFR inhibitors based on new morpholine-linked chromene-thiazole hybrids: One-pot synthesis and in silico study. Journal of Molecular Structure 1248, pages 131476.
Crossref
Sherif M. H. Sanad & Ahmed E. M. Mekky. (2021) 3‐Aminopyrazolo[3,4‐ b ]pyridine: Effective Precursor for Barium Hydroxide‐Mediated Three Components Synthesis of New Mono‐ and Bis(pyrimidines) with Potential Cytotoxic Activity . Chemistry & Biodiversity 19:1.
Crossref
Sherif M. H. Sanad, Ahmed E. M. Mekky, Ahmed Y. Said & Mohamed A. A. Elneairy. (2021) Pyridine‐2( 1 H )‐thiones: Versatile precursors for one‐pot synthesis of new nicotinonitrile‐thiazole hybrids . Journal of Heterocyclic Chemistry 58:7, pages 1461-1471.
Crossref
Sima Kalhor, Mahmoud Zarei, Hassan Sepehrmansourie, Mohammad Ali Zolfigol, Hu Shi, Jinping Wang, Jalal Arjomandi, Masoumeh Hasani & Romana Schirhagl. (2021) Novel uric acid-based nano organocatalyst with phosphorous acid tags: Application for synthesis of new biologically-interest pyridines with indole moieties via a cooperative vinylogous anomeric based oxidation. Molecular Catalysis 507, pages 111549.
Crossref
Clementina M.M. Santos & Artur M.S. Silva. 2021. 501 563 .
Sherif M. H. Sanad & Ahmed E. M. Mekky. (2020) Novel nicotinonitrile-coumarin hybrids as potential acetylcholinesterase inhibitors: design, synthesis, in vitro and in silico studies. Journal of the Iranian Chemical Society 18:1, pages 213-224.
Crossref
Ahmed E.M. Mekky & Sherif M.H. Sanad. (2020) Synthesis and antibacterial evaluation of novel mono- and bis(2H-chromen-2-imine) hybrids linked to heteroarene units. Mendeleev Communications 30:6, pages 762-764.
Crossref
Sherif M. H. Sanad & Ahmed E. M. Mekky. (2020) Efficient synthesis and characterization of novel bis‐heterocyclic derivatives and benzo‐fused macrocycles containing oxazolone or imidazolone subunits . Journal of Heterocyclic Chemistry 57:11, pages 3930-3942.
Crossref
Ahmed E.M. Mekky & Sherif M.H. Sanad. (2020) Novel bis(pyrazole-benzofuran) hybrids possessing piperazine linker: Synthesis of potent bacterial biofilm and MurB inhibitors. Bioorganic Chemistry 102, pages 104094.
Crossref
Sherif M. H. Sanad, Ahmed A. M. Ahmed & Ahmed E. M. Mekky. (2020) Synthesis, in‐vitro and in‐silico study of novel thiazoles as potent antibacterial agents and MurB inhibitors . Archiv der Pharmazie 353:4.
Crossref
Sherif M. H. Sanad, Ahmed A. M. Ahmed & Ahmed E. M. Mekky. (2019) Efficient synthesis and molecular docking of novel antibacterial pyrimidines and their related fused heterocyclic derivatives. Journal of Heterocyclic Chemistry 57:2, pages 590-605.
Crossref
Ahmed E. M. Mekky, Sherif M. H. Sanad & Ahmed A. M. Ahmed. (2019) Microwave Assisted Three Component One‐pot Synthesis of Bis(aminoazolo[1,5‐ a ]pyrimidines) and Bis(aminoazino[1,2‐ a ]benzimidazoles) Bearing Thiazole Moiety . ChemistrySelect 4:33, pages 9710-9715.
Crossref

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