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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 50, 2020 - Issue 1
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ARTICLE

Amide derivatives of 4-azaindole: Design, synthesis, and EGFR targeting anticancer agents

Puli Venkat SwamyDepartment of Chemistry, Koneru Lakshmaiah Education Foundation, Guntur, Andhra Pradesh, India; Correspondence[email protected]
,
Vukoti Kiran KumarDepartment of Chemistry, Koneru Lakshmaiah Education Foundation, Guntur, Andhra Pradesh, India;
,
Ruddarraju Radhakrishnam RajuDr. MACS Bio-Pharma Pvt. Ltd, MedakTelangana, India;
,
Regalla Venkata ReddyDepartment of Chemistry, Koneru Lakshmaiah Education Foundation, Guntur, Andhra Pradesh, India;
,
Anindita ChatterjeeDepartment of Chemistry, Koneru Lakshmaiah Education Foundation, Guntur, Andhra Pradesh, India;
,
Gangarapu KiranDepartment of Pharmaceutical Analysis and Chemistry, School of Pharmacy, Anurag Group of Institutions, Medchal, Telangana, India;
&
Gattu SridharOrganic and Biomolecular Chemistry Division, CSIR-Indian Institute of Chemical Technology, Hyderabad, India
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Pages 71-84 | Received 14 Jul 2019, Published online: 07 Nov 2019

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Pravin S. Bhale, Hemant V. Chavan, Sadanand N. Shringare, Vijay M. Khedkar, Radhakrishna M. Tigote, Nikita N. Mali, Tukaram D. Jadhav, Nitin B. Kamble, Swati P. Kolat, Babasaheb P. Bandgar & Harshal S. Patil. (2022) Design, synthesis of anticancer and anti-inflammatory 4-(1-methyl-1H-indol-3-yl)-6-(methylthio) pyrimidine-5-carbonitriles. Synthetic Communications 52:5, pages 733-744.
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Articles from other publishers (10)

. (2023) Molecular Docking, Design, Synthesis, Characterization and Pharmacological Evaluation of New 2-hydrazinel Oxazole containing moiety as anti-proliferative activity. Bionatura 8:CSS 4, pages 1-15.
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Jie He, Leixuan Luo, Shidi Xu, Feiyi Yang & Wufu Zhu. (2022) Pyrrole‐based EGFR inhibitors for the treatment of NCSLC : Binding modes and SARs investigations . Chemical Biology & Drug Design 101:1, pages 195-217.
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T Shreedhar Reddy, Sanjay Rai & Shiva Kumar Koppula. (2022) Synthesis of indole-tetrazole coupled aromatic amides; In vitro anticancer activity, in vitro tubulin polymerization inhibition assay and in silico studies. Journal of Molecular Structure 1267, pages 133556.
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Ashima Dhiman, Rupam Sharma & Rajesh K. Singh. (2022) Target-based anticancer indole derivatives and insight into structure‒activity relationship: A mechanistic review update (2018–2021). Acta Pharmaceutica Sinica B 12:7, pages 3006-3027.
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Swanand Kulkarni, Kamalpreet Kaur & Vikas Jaitak. (2022) Recent Developments in Oxazole Derivatives as Anticancer Agents: Review on Synthetic Strategies, Mechanism of Action and SAR Studies. Anti-Cancer Agents in Medicinal Chemistry 22:10, pages 1859-1882.
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Venu kudapa, Saritha B & B. B. V. Sailaja. (2022) Synthesis and Anticancer Activity of Some New 4-Azaindoleisoxazoles. Russian Journal of General Chemistry 92:3, pages 470-476.
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Dorina Amariucai-Mantu, Vasilichia Antoci, Monica Cornelia Sardaru, Cristina Maria Al Matarneh, Ionel Mangalagiu & Ramona Danac. (2022) Fused pyrrolo-pyridines and pyrrolo-(iso)quinoline as anticancer agents. Physical Sciences Reviews 0:0.
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D. Gouthami, B. Srinivas & M Ravinder. (2021) Synthesis of Quinoxlines Containing 1,2,3-Triazoles and Their Anti-Bacterial and Anti-Cancer Activity. Russian Journal of Bioorganic Chemistry 47:4, pages 882-888.
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Yu Han, Wei Dong, Qunqun Guo, Xiufen Li & Longjiang Huang. (2020) The importance of indole and azaindole scaffold in the development of antitumor agents. European Journal of Medicinal Chemistry 203, pages 112506.
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Xinjia Yan, Jing Wen, Lin Zhou, Lei Fan, Xiaobo Wang & Zhi Xu. (2020) Current Scenario of 1,3-oxazole Derivatives for Anticancer Activity. Current Topics in Medicinal Chemistry 20:21, pages 1916-1937.
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