Advanced search
Publication Cover
Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 50, 2020 - Issue 8
Submit an article Journal homepage
487
Views
24
CrossRef citations to date
0
Altmetric
SYNTHETIC COMMUNICATIONS REVIEWS

Synthesis, DFT study, molecular docking and insecticidal evaluation of some pyrazole-based tetrahydropyrimidine derivatives

Karema N. M. HalimChemistry Department, Faculty of Science, Ain Shams University, Abassia, Egypt
,
Sayed K. RamadanChemistry Department, Faculty of Science, Ain Shams University, Abassia, EgyptCorrespondence[email protected]
ORCID Iconhttp://orcid.org/0000-0003-2743-6544
ORCID Icon,
Sameh A. RizkChemistry Department, Faculty of Science, Ain Shams University, Abassia, EgyptORCID Iconhttp://orcid.org/0000-0002-8232-5399
ORCID Icon &
Maher A. El-HashashChemistry Department, Faculty of Science, Ain Shams University, Abassia, EgyptORCID Iconhttp://orcid.org/0000-0003-2550-8479
ORCID Icon
Pages 1159-1175 | Received 13 Dec 2019, Published online: 11 Mar 2020

Citations (24)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (11)

Eman A. E. El-Helw, Aya M. Abdelrahman, Abdelgawad A. Fahmi & Sameh A. Rizk. (2023) Synthesis, Density Functional Theory, Insecticidal Activity, and Molecular Docking of Some N-Heterocycles Derived from 2-((1,3-Diphenyl-1H-Pyrazol-4-yl)Methylene)Malonyl Diisothiocyanate. Polycyclic Aromatic Compounds 43:9, pages 8265-8281.
Read now
Youssef M. Youssef, Mohammad E. Azab, Galal A. Elsayed, Amira A. El-Sayed & Eman A. E. El-Helw. (2023) Synthesis and Antiproliferative Screening of Some Heterocycles Derived from 4-((5-Chloro-3-Methyl-1-Phenyl-1H-Pyrazol-4-yl)Methylene)-2-Phenyloxazol-5(4H)-One. Polycyclic Aromatic Compounds 43:8, pages 7152-7163.
Read now
Sameh A. Rizk, Salwa S. Abdelwahab & Abdullah M. Abdo. (2023) Ultrasonic-Assisted Synthesis and Quantum Chemical Analysis of Spiro[Indoline-3,3′-Pyrazol]-2-One Derivatives as Effective Bactericidal and Viricidal Agents. Polycyclic Aromatic Compounds 43:3, pages 2656-2671.
Read now
Aya M. Abdelrahman, Abdelgawad A. Fahmi, Sameh A. Rizk & Eman A. E. El-Helw. (2023) Synthesis, DFT and Antitumor Activity Screening of Some New Heterocycles Derived from 2,2'-(2-(1,3-Diphenyl-1H-Pyrazol-4-yl)Ethene-1,1-Diyl)Bis(4H-Benzo[d][1,3]Oxazin-4-One). Polycyclic Aromatic Compounds 43:1, pages 721-739.
Read now
Nitin Rode, Aafaq Tantray, Amruta Shelar, Rajendra Patil & Santosh Terdale. (2022) Amino acid ionic liquid-catalyzed synthesis, anti-Leishmania activity, molecular docking, molecular dynamic simulation, and ADME study of 3,4-dihydropyrimidin-2(1H)-(thio)ones. Synthetic Communications 52:2, pages 190-204.
Read now
Mohamed M. Kaddah, Alaa R. I. Morsy, Abdelgawad A. Fahmi, Mustafa M. Kamel, Mounir M. Elsafty, Sameh A. Rizk & Sayed K. Ramadan. (2021) Synthesis and biological activity on IBD virus of diverse heterocyclic systems derived from 2-cyano-N'-((2-oxo-1,2-dihydroquinolin-3-yl)methylene)acetohydrazide. Synthetic Communications 51:22, pages 3366-3378.
Read now
Sayed K. Ramadan, Nasser A. Ibrahim, Sarah A. El-Kaed & Eman A. E. El-Helw. (2021) New potential fungicides pyrazole-based heterocycles derived from 2-cyano-3-(1,3-diphenyl-1H-pyrazol-4-yl) acryloyl isothiocyanate. Journal of Sulfur Chemistry 42:5, pages 529-546.
Read now
Mohamed M Kaddah, Abdelgawad A. Fahmi, Mustafa M. Kamel, Sayed K. Ramadan & Sameh A. Rizk. (2021) Synthesis, characterization, computational chemical studies and antiproliferative activity of some heterocyclic systems derived from 3-(3-(1,3-diphenyl-1H-pyrazol-4-yl)acryloyl)-2H-chromen-2-one. Synthetic Communications 51:12, pages 1798-1813.
Read now
Nourhan M. Gad, Wael S. I. Abou-Elmagd, David S. A. Haneen & Sayed K. Ramadan. (2021) Reactivity of 5-phenyl-3-[(2-chloroquinolin-3-yl)methylene] furan-2(3H)-one towards hydrazine and benzylamine: A comparative study. Synthetic Communications 51:9, pages 1384-1397.
Read now
Sayed K. Ramadan, Ahmed K. El-Ziaty & Eman A. E. El-Helw. (2021) Synthesis and antioxidant evaluation of some heterocyclic candidates from 3-(1,3-diphenyl-1H-pyrazol-4-yl)-2-(4-oxo-4H-benzo[d][1,3]oxazin-2-yl)propenonitrile. Synthetic Communications 51:8, pages 1272-1283.
Read now
Hanan A. Sallam, Amna S. Elgubbi & Eman A. E. El-Helw. (2020) Synthesis and antioxidant screening of new 2-cyano-3-(1,3-diphenyl-1H-pyrazol-4-yl)acryloyl amide derivatives and some pyrazole-based heterocycles. Synthetic Communications 50:13, pages 2066-2077.
Read now

Articles from other publishers (13)

Rajae Salim, Sara Hajib, Rajesh Haldhar, Nadia Arrousse, Seong-Cheol Kim, Elhachmia Ech-chihbi, Abeer A. AlObaid, Anouar Alami & Mustapha Taleb. (2024) Electrochemical and theoretical investigations to comprehend the adsorption of new pyrazole derivative on mild steel in 1 M HCl. Journal of Molecular Structure 1299, pages 137209.
Crossref
Nian-Juan Pan, Chang Yan, Qiang Fei & Wen-Neng Wu. (2023) Crystal structure of (1-methyl-3-(trifluoromethyl)-1 H -pyrazol-4-yl)(4-((2-methyl-6-(trifluoromethyl)pyrimidin-4-yl)amino)piperidin-1-yl)methanone, C 17 H 18 F 6 N 6 O . Zeitschrift für Kristallographie - New Crystal Structures 238:5, pages 903-905.
Crossref
Mona A. Shalaby, Sameh A. Rizk & Asmaa M. Fahim. (2023) Synthesis, reactions and application of chalcones: a systematic review. Organic & Biomolecular Chemistry 21:26, pages 5317-5346.
Crossref
Sayed K. Ramadan, Doaa R. Abdel Haleem, Hisham S. M. Abd-Rabboh, Nourhan M. Gad, Wael S. I. Abou-Elmagd & David S. A. Haneen. (2022) Synthesis, SAR studies, and insecticidal activities of certain N-heterocycles derived from 3-((2-chloroquinolin-3-yl)methylene)-5-phenylfuran-2(3 H )-one against Culex pipiens L. larvae . RSC Advances 12:22, pages 13628-13638.
Crossref
Kurls E. Anwer, Galal H. Sayed & Ramadan M. Ramadan. (2022) Synthesis, spectroscopic, DFT calculations, biological activities and molecular docking studies of new isoxazolone, pyrazolone, triazine, triazole and amide derivatives. Journal of Molecular Structure 1256, pages 132513.
Crossref
Sayed K. Ramadan & Sameh A. Rizk. (2021) Synthesis, density functional theory, and cytotoxic activity of some heterocyclic systems derived from 3-(3-(1,3-diphenyl-1H-pyrazol-4-yl)acryloyl)-2H-chromen-2-one. Journal of the Iranian Chemical Society 19:1, pages 187-201.
Crossref
José Eduardo Cadena-Cruz, Luis M. Guamán-Ortiz, Juan Carlos Romero-Benavides, Natalia Bailon-Moscoso, Kevin E. Murillo-Sotomayor, Nadia V. Ortiz-Guamán & Jorge Heredia-Moya. (2021) Synthesis of 4,4′-(arylmethylene)bis(3-methyl-1-phenyl-1H-pyrazol-5-ols) and evaluation of their antioxidant and anticancer activities. BMC Chemistry 15:1.
Crossref
Eman A. Ghareeb, Naglaa F.H. Mahmoud, Eman A. El-Bordany & Eman A.E. El-Helw. (2021) Synthesis, DFT, and eco-friendly insecticidal activity of some N-heterocycles derived from 4-((2-oxo-1,2-dihydroquinolin-3-yl)methylene)-2-phenyloxazol-5(4H)-one. Bioorganic Chemistry 112, pages 104945.
Crossref
Eman A. E. El‐Helw, Alaa R. I. Morsy & Ahmed I. Hashem. (2021) Evaluation of some new heterocycles bearing 2‐oxoquinolyl moiety as immunomodulator against highly pathogenic avian influenza virus ( H 5 N 8 ) . Journal of Heterocyclic Chemistry 58:4, pages 1003-1014.
Crossref
Talaat I. El-Emary, Shawkat A. Abdel-Mohsen & Shereen A. Mohamed. (2021) An Efficient Synthesis and Reactions of 5-Acetyl-6-Methyl-4-(1,3-Diphenyl-1H-Pyrazol-4-yl)-3,4-Dihydropyrmidin-2(1H)-Thione as Potential Antimicrobial and Anti-Inflammatory Agents. Russian Journal of Bioorganic Chemistry 47:2, pages 561-571.
Crossref
Karema N. M. Halim, Sameh A. Rizk, Maher A. El‐Hashash & Sayed K. Ramadan. (2020) Straightforward synthesis, antiproliferative screening, and density functional theory study of some pyrazolylpyrimidine derivatives. Journal of Heterocyclic Chemistry 58:2, pages 636-645.
Crossref
Sayed K. Ramadan, Ahmed K. El‐Ziaty & Rania S. Ali. (2020) Synthesis, antiproliferative activity, and molecular docking of some N ‐heterocycles bearing a pyrazole scaffold against liver and breast tumors . Journal of Heterocyclic Chemistry 58:1, pages 290-304.
Crossref
Sayed K. Ramadan, Karema N. M. Halim, Sameh A. Rizk & Maher A. El-Hashash. (2020) Cytotoxic activity and density functional theory studies of some 1,3-diphenylpyrazolyltetrahydropyrimidine derivatives. Journal of the Iranian Chemical Society 17:7, pages 1575-1589.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.