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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 50, 2020 - Issue 15
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SYNTHETIC COMMUNICATIONS REVIEWS

Recent advances and perspectives on the synthesis and C–H bond functionalization of quinoxalin-2(1H)-one

Prasanjit GhoshDepartment of Chemistry, University of North Bengal, Darjeeling, IndiaCorrespondence[email protected]
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Sajal DasDepartment of Chemistry, University of North Bengal, Darjeeling, IndiaView further author information
Pages 2266-2312 | Received 04 Sep 2019, Published online: 20 May 2020

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Sourav Mal & Manoranjan Jana. (2022) Sulfonyl hydrazide induced sulfenylation of imidazoheteroarenes: A ‘catalyst and solvent free’ protocol. Synthetic Communications 52:7, pages 1059-1068.
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Lusina Mantry & Parthasarathy Gandeepan. (2024) Visible-Light-Induced PhI(OAc) 2 -Mediated Alkylation of Heteroarenes with Simple Alkanes and Ethers . The Journal of Organic Chemistry.
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Ming Gong, Qian Wu, Jung Keun Kim, Mengmeng Huang, Yabo Li, Yangjie Wu & Jong Seung Kim. (2024) Electric-field-controlled highly regioselective thiocyanation of N-containing heterocycles. Science China Chemistry 67:4, pages 1263-1269.
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Buddhadeb Pal, Sathi Sahoo & Prasenjit Mal. (2024) Atom Transfer Radical Addition Reactions of Quinoxalin-2(1 H )-ones with CBr 4 and Styrenes Using Mes-Acr-MeClO 4 Photocatalyst . The Journal of Organic Chemistry 89:3, pages 1784-1796.
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Gaurav Badhani, Valvi Mangesh Biramya & Subbarayappa Adimurthy. (2023) Ionic liquid-catalysed regioselective oxygenation of quinoxalin-2(1 H )-ones under visible-light conditions . New Journal of Chemistry 47:47, pages 21596-21599.
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Hang Gong, Fangyuan Zhou & Changqun Cai. (2023) Construction of benzoheterocycles by the reaction of α-arylglyoxylic acids and ortho -functionalized aniline under mild and minimal conditions . Organic & Biomolecular Chemistry 21:37, pages 7639-7642.
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Ke‐Li Wang, Hong‐Tao Ji, Li‐Juan Ou & Wei‐Min He. (2023) Three‐Component Reactions of Quinoxalin‐2(1 H )‐ones: Recent Advances . European Journal of Organic Chemistry.
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Devidas A. More, Sachin R. Shirsath & M. Muthukrishnan. (2023) Metal- and Photocatalyst-Free, Visible-Light-Initiated C3 α-Aminomethylation of Quinoxalin-2(1 H )-ones via Electron Donor–Acceptor Complexes . The Journal of Organic Chemistry 88:18, pages 13339-13350.
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Jennie Liao, David N. Hunter, Ugochinyere Nancy Oloyede, Joseph W. McLaughlin, Cheng Wang & Abdellatif El Marrouni. (2023) Metal-Free Addition of Alkyl Bromides to Access 3,3-Disubstituted Quinoxalinones Enabled by Visible-Light Photoredox Catalysis. The Journal of Organic Chemistry 88:16, pages 11762-11766.
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Gaurav Badhani & Subbarayappa Adimurthy. (2023) Water‐Mediated C−H Cyanation of Quinoxalin‐2(1 H )‐ones and Quinoxalines Under Visible‐Light Conditions . ChemistrySelect 8:27.
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Sha Peng, Long-Yong Xie & Luo Yang. (2023) A visible-light-mediated cascade reaction of quinoxalin-2(1 H )-ones, alkenes, and sulfinic acids . Organic & Biomolecular Chemistry 21:19, pages 4109-4113.
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Bin Sun, Xiao‐Li Tang, Xiaohui Zhuang, Lan Ling, Panyi Huang, Jiayang Wang & Can Jin. (2023) Visible‐Light‐Driven Multicomponent Radical Cascade Versatile Alkylation of Quinoxalinones Enabled by Electron Donor Acceptor Complex in Water. Advanced Synthesis & Catalysis 365:7, pages 1020-1026.
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Mio Matsumura, Honoka Nojima, Yuki Kitamura, Yuki Murata & Shuji Yasuike. (2023) Palladium-catalyzed C–H arylation of quinoxalin-2(1H)-ones with triarylantimony difluorides. Journal of Organometallic Chemistry 989, pages 122639.
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Qiming Yang, Biao Wang, Mian Wu & Yi-Zhu Lei. (2023) Recent Developments in Direct C–H Functionalization of Quinoxalin-2(1H)-Ones via Multi-Component Tandem Reactions. Molecules 28:6, pages 2513.
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Sonam, Vikki N. Shinde, Krishnan Rangan & Anil Kumar. (2023) Selectfluor-Mediated Regioselective C-3 Alkoxylation, Amination, Sulfenylation, and Selenylation of Quinoxalin-2(1 H )-ones . The Journal of Organic Chemistry 88:4, pages 2344-2357.
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Kévin Renault, Pierre‐Yves Renard & Cyrille Sabot. (2022) Quinoxalin‐2(1 H )‐ones: Chemical Synthesis, Fluorescence Properties and Applications . European Journal of Organic Chemistry 2022:48.
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Hesheng Wang, Siyu Li, Yue Cui, Minqiang Liu, Xiubin Bu, Hua Tian & Xiaobo Yang. (2022) A covalent organic framework-catalyzed visible-light-induced three-component cascade synthesis of trifluoroalkyl and trifluoroalkenyl quinoxalin-2(1 H )-one derivatives . New Journal of Chemistry 46:42, pages 20412-20418.
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Devidas A. More, M. Mujahid & M. Muthukrishnan. (2022) Metal‐ And Light‐Free Direct C‐3 Ketoalkylation of Quinoxalin‐2(1 H )‐Ones with Cyclopropanols in Aqueous Medium . ChemistrySelect 7:39.
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Runye Gao, Fang Wang, Xiao Geng, Chuan-Ying Li & Lei Wang. (2022) Visible-Light-Initiated Difunctionalization of Quinoxalin-2(1 H )-ones with Acyloxy Nitroso Compounds . Organic Letters 24:39, pages 7118-7122.
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Yuan Li, Zitong Fu, Yawei Shen, Jie Zhu, Kai Luo & Lei Wu. (2022) Divergent Auto‐oxidative Alkylation and Alkanoacylation of Quinoxalin‐2(1 H )‐ones with Aliphatic Aldehydes . Asian Journal of Organic Chemistry 11:10.
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Min Wang, Jie Liu, Yicheng Zhang & Peipei Sun. (2022) Decarbonylative C3‐Alkylation of Quinoxalin‐2(1 H )‐Ones with Aliphatic Aldehydes via Photocatalysis . Advanced Synthesis & Catalysis 364:15, pages 2660-2665.
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Ningning Zhou, Ruiyue Liu, Chunmeng Zhang, Kun Wang, Jiaxu Feng, Xia Zhao & Kui Lu. (2022) Photoinduced Three-Component Difluoroalkylation of Quinoxalinones with Alkenes via Difluoroiodane(III) Reagents. Organic Letters 24:19, pages 3576-3581.
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Min Wang, Yicheng Zhang, Xinyu Yang & Peipei Sun. (2022) Phenanthrenequinone (PQ) catalyzed cross-dehydrogenative coupling of alkanes with quinoxalin-2(1 H )-ones and simple N-heteroarenes under visible light irradiation . Organic & Biomolecular Chemistry 20:12, pages 2467-2472.
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Yun‐Chao Zhang, Yang Chen, Jing Sun, Jing‐Yun Wang & Ming‐Dong Zhou. (2022) Visible‐light‐promoted Radical Cyclization/Arylation Cascade for the Construction of α, α ‐Difluoro‐ γ ‐Lactam‐Fused Quinoxalin‐2( 1 H )‐Ones . Chinese Journal of Chemistry 40:6, pages 713-718.
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Xin Sun, Chaofan Qu, Chaorui Ma, Xiaowei Zhao, Guobi Chai & Zhiyong Jiang. (2022) Photoredox Catalytic Cascade Radical Addition to Construct 1,4- Diketone-Functionalized Quinoxalin-2(1 H )-one Derivatives . Chinese Journal of Organic Chemistry 42:5, pages 1396.
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Zhi-Peng Ye, Fang Liu, Xin-Yu Duan, Jie Gao, Jian-Ping Guan, Jun-An Xiao, Hao-Yue Xiang, Kai Chen & Hua Yang. (2021) Visible Light-Promoted Radical Relay Cyclization/C–C Bond Formation of N -Allylbromodifluoroacetamides with Quinoxalin-2(1 H )-ones . The Journal of Organic Chemistry 86:23, pages 17173-17183.
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Xiu Yang, Wei-Dong Meng, Xiu-Hua Xu & Yangen Huang. (2021) Photoredox-catalyzed 2,2,2-trifluoroethylation and 2,2-difluoroethylation of alkenes with concomitant introduction of a quinoxalin-2(1 H )-one moiety . Organic Chemistry Frontiers 8:23, pages 6597-6602.
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Kiran, Payal Rani, Sandhya Chahal, Jayant Sindhu, Sudhir Kumar, Rajender S. Varma & Rajvir Singh. (2021) Transition metal-free C-3 functionalization of quinoxalin-2(1 H )-ones: recent advances and sanguine future . New Journal of Chemistry 45:40, pages 18722-18763.
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He Chen, Li-Na Guo, Qing-Xin Sun, Lei Chen, Jing-Qi Tao & Pin Gao. (2021) Copper-catalyzed redox neutral ketoalkylation of Csp 2 –H bonds via C–C bond cleavage . Organic Chemistry Frontiers 8:20, pages 5866-5871.
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Dandan Li, Xiaochen Wang, Shanshan Li, Chenyu Fu, Qianqian Li, Dongtao Xu & Yingying Ma. (2021) Recent Advances in Electrochemical C(3)—H Functionalization of Quinoxalin-2(1 H )-ones . Chinese Journal of Organic Chemistry 41:12, pages 4610.
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