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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 50, 2020 - Issue 22
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Articles

Straightforward synthesis of 2-chloro-N-(5-(cyanomethyl)-1,3,4-thiadiazol-2-yl)benzamide as a precursor for synthesis of novel heterocyclic compounds with insecticidal activity

Ali M. M. Mohameda Department of Chemistry, Faculty of Science, Ain Shams University, Cairo, Abbassia, Egypt
,
Mahmoud F. Ismaila Department of Chemistry, Faculty of Science, Ain Shams University, Cairo, Abbassia, EgyptCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-9243-6236
ORCID Icon,
Hassan M. F. Madkoura Department of Chemistry, Faculty of Science, Ain Shams University, Cairo, Abbassia, Egypt
,
Aly Fahmy Alyb Pesticide Formulations Department, Central Agricultural Pesticide Lab., Agricultural research Center, Giza, Dokky, Egypt
&
Marwa S. Salema Department of Chemistry, Faculty of Science, Ain Shams University, Cairo, Abbassia, Egypt
Pages 3424-3442 | Received 26 Apr 2020, Published online: 06 Aug 2020

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Amira A. El-Sayed, Galal A. Elsayed, Sameh A. Rizk & Mahmoud F. Ismail. (2024) Synthesis, Insecticidal Activity and DFT Study of 1,2,4-Triazolidinthione, 1,3,5-Oxadiazine and Thiourea Derivatives. Organic Preparations and Procedures International 56:1, pages 38-51.
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Mourad Fawzi, Abdoullah Bimoussa, Yassine Laamari, Abdellah N'ait Oussidi, Ali Oubella, El Mostafa Ketatni, Mohamed Saadi, Lahcen El Ammari, Hamid Morjani, Moulay Youssef Ait Itto & Aziz Auhmani. (2023) New (S)-verbenone-isoxazoline-1,3,4-thiadiazole Hybrids: Synthesis, Anticancer Activity and Apoptosis-Inducing Effect. Future Medicinal Chemistry 15:17, pages 1603-1619.
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B.Y. Cai, T.S. Zhao, D.G. Qin & G.G. Tu. (2023) Synthesis, antiproliferative and 4D-QSAR studies of thiadiazole derivatives bearing acrylamide moiety as EGFR inhibitors. SAR and QSAR in Environmental Research 34:4, pages 341-359.
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Mai Y. Hamed, Aly Fahmy Aly, Nashwa Hamed Abdullah & Mahmoud F. Ismail. (2023) Synthesis, Characterization and Antifungal Evaluation of Novel Pyridazin-3(2H)-One Derivatives. Polycyclic Aromatic Compounds 43:3, pages 2356-2375.
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Mahmoud F. Ismail, Aly Fahmy Aly, Salwa S. Abdel-Wahab & Amira A El-Sayed. (2023) Synthesis, Characterization and Insecticidal Activity against Cotton Leaf Worm of New Heterocyclics Which Scaffold on Hydrazide-Hydrazone Derivative. Polycyclic Aromatic Compounds 43:2, pages 1288-1308.
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Samar Mosad Mohamed Ali, Marwa S. Salem, Hassan M. F. Madkour & Alaa Zidan. (2023) 2(1H)-Pyridone and Quinolone as Synthon for Efficient and Simple Synthesis of Polysubstituted Pyridines and Quinolines. Polycyclic Aromatic Compounds 43:1, pages 328-342.
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Mahmoud F. Ismail, Hassan M. F. Madkour, Marwa S. Salem, Ali M. M. Mohamed & Aly Fahmy Aly. (2021) Design, synthesis and insecticidal activity of new 1,3,4-thiadiazole and 1,3,4-thiadiazolo[3,2-a]pyrimidine derivatives under solvent-free conditions. Synthetic Communications 51:17, pages 2644-2660.
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Marwa S. Salem, Selima A. M. Al-Mabrook & Maher A. E. M. El-Hashash. (2021) Design, Synthesis and Antiproliferative Activity of Novel Heterocycles from 6-Iodo-2-phenyl-4H-benzo[d][1,3]thiazine-4-thione. Journal of Sulfur Chemistry 42:3, pages 251-263.
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Mahmoud F. Ismail, Asmaa Aboelnaga, Mohamed M. Naguib & Hind M. Ismaeel. Synthesis, Anti-Proliferative Activity, DFT and Docking Studies of Some Novel Chloroquinoline-Based Heterocycles. Polycyclic Aromatic Compounds 0:0, pages 1-32.
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Articles from other publishers (11)

Samir Bondock, Nada Alabbad, Aisha Hossan & Moaz M. Abdou. (2024) 1-Cyanoacetylthiosemicarbazides: Recent Advances in their Synthesis, Reactivity in Heterocyclization, and Bio-Applications. Mini-Reviews in Organic Chemistry 21:4, pages 409-423.
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Mahmoud F. Ismail, Amira A. El‐Sayed, Eslam M. Hosni & Aya I. Hassaballah. (2024) Synthesis and evaluation of larvicidal efficacy against C. pipiens of some new heterocyclic compounds emanated from 2‐cyano‐ N ′‐(2‐(2,4‐dichlorophenoxy)acetyl)acetohydrazide . Chemistry & Biodiversity 21:2.
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Eman El-Sayed Ebead, Asmaa Aboelnaga, Ekhlass Nassar, Mohamed M. Naguib & Mahmoud F. Ismail. (2023) Ultrasonic-induced synthesis of novel diverse arylidenes via Knoevenagel condensation reaction. Antitumor, QSAR, docking and DFT assessment . RSC Advances 13:42, pages 29749-29767.
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Mustafa A. S. Gouda, Mounir A. I. Salem, Magda I. Marzouk, Naglaa F. H. Mahmoud & Mahmoud F. Ismail. (2023) Synthesis, Antioxidant and Antiproliferative Evaluation, Molecular Docking and DFT Studies of Some Novel Coumarin and Fused Coumarin Derivatives. Chemistry & Biodiversity 20:7.
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Mirna T. Helmy, Farid M. Sroor, Abdelmageed M. Othman, Hamdi M. Hassaneen, Fatma M. Saleh & Mohamed A. Mohamed Teleb. (2022) Design, synthesis and in‐vitro evaluation of new furan‐substituted thiadiazolyl hydrazone derivatives as promising antimicrobial agents . Journal of Heterocyclic Chemistry 60:4, pages 585-595.
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Mahmoud F. Ismail, Ahmed I. Hashem, Rasha A. Sleem & Aya I. Hassaballah. (2023) Utility of 5,5′‐Methylenebis(2‐hydroxybenzaldehyde) – cyanoacetohydrazide Hybrid as Scaffold for the Synthesis of Bis‐Heterocyclic Moieties and Study of Their Insecticidal Activity. ChemistrySelect 8:9.
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Tulika Anthwal, Sarvesh Paliwal & Sumitra Nain. (2022) Diverse Biological Activities of 1,3,4-Thiadiazole Scaffold. Chemistry 4:4, pages 1654-1671.
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Li Dou, Huabin Shi, Xue Niu, Hong Zhang, Kankan Zhang & Zhibing Wu. (2022) Design, synthesis and antifungal mechanism of novel acetophenone derivatives containing 1,3,4-thiadiazole-2-thioethers. New Journal of Chemistry 46:19, pages 9017-9023.
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Oya Unsal Tan & Merve Zengin. (2021) Insights into the chemistry and therapeutic potential of acrylonitrile derivatives. Archiv der Pharmazie 355:3.
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Arif Mermer, Turgut Keles & Yakup Sirin. (2021) Recent studies of nitrogen containing heterocyclic compounds as novel antiviral agents: A review. Bioorganic Chemistry 114, pages 105076.
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Mohammed M.S. Wassel, Yousry A. Ammar, Gameel A.M. Elhag Ali, Amany Belal, Ahmed B.M. Mehany & Ahmed Ragab. (2021) Development of adamantane scaffold containing 1,3,4-thiadiazole derivatives: Design, synthesis, anti-proliferative activity and molecular docking study targeting EGFR. Bioorganic Chemistry 110, pages 104794.
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