Advanced search
Publication Cover
Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 51, 2021 - Issue 21
Submit an article Journal homepage
470
Views
23
CrossRef citations to date
0
Altmetric
Articles

New thiazole and thiazole-chromene hybrids possessing morpholine units: Piperazine-mediated one-pot synthesis of potential acetylcholinesterase inhibitors

Ahmed E. M. Mekkya Faculty of Science , Chemistry Department, Cairo University, Giza, Egypt
,
Sherif M. H. Sanada Faculty of Science , Chemistry Department, Cairo University, Giza, EgyptCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-0186-6418
ORCID Icon &
Tamer T. El-Idreesya Faculty of Science , Chemistry Department, Cairo University, Giza, Egypt;b Department of Chemistry, School of Sciences and Engineering, The American University in Cairo, New Cairo, Egypt
Pages 3332-3344 | Received 04 Jun 2021, Published online: 29 Aug 2021

Citations (23)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (8)

Ahmed M. Abdelfattah, Sherif M. H. Sanad & Ahmed E. M. Mekky. (2023) Regioselective synthesis and antibacterial screening of new thiazol-2(3H)-imines linked to arene or chromene units. Synthetic Communications 53:17, pages 1398-1411.
Read now
Hasnain Mehmood, Tashfeen Akhtar, Muhammad Haroon, Muhammad Shah, Umer Rashid & Simon Woodward. (2023) Synthesis of Hydrazinylthiazole Carboxylates: A Mechanistic Approach for Treatment of Diabetes and Its Complications. Future Medicinal Chemistry 15:13, pages 1149-1165.
Read now
Mohamed A. A. Elneairy, Sherif M. H. Sanad & Ahmed E. M. Mekky. (2023) One-pot synthesis and antibacterial screening of new (nicotinonitrile-thiazole)-based mono- and bis(Schiff bases) linked to arene units. Synthetic Communications 53:3, pages 245-261.
Read now
Ahmed E. M. Mekky & Sherif M. H. Sanad. (2022) Microwave-assisted synthesis of nicotinonitrile and/or arene-linked bis(chromene-thiazoles) as new VRE and MRSA inhibitors. Synthetic Communications 52:24, pages 2276-2290.
Read now
Ahmed E. M. Mekky & Sherif M. H. Sanad. (2022) New thiazole-based bis(Schiff bases) linked to arene units as potential MRSA inhibitors. Synthetic Communications 52:23, pages 2205-2218.
Read now
Sherif M. H. Sanad & Ahmed E. M. Mekky. (2022) [3 + 2] Cycloaddition synthesis of new (nicotinonitrile-chromene) hybrids linked to pyrazole units as potential acetylcholinesterase inhibitors. Synthetic Communications 52:16, pages 1672-1684.
Read now
Nadia Hanafy Metwally, Thoraya Hossam Koraa & Sherif Mohamed Hamed Sanad. (2022) Green one-pot synthesis and in vitro antibacterial screening of pyrano[2,3-c]pyrazoles, 4H-chromenes and pyrazolo[1,5-a]pyrimidines using biocatalyzed pepsin. Synthetic Communications 52:8, pages 1139-1154.
Read now
Ahmed A. M. Ahmed, Ahmed E. M. Mekky & Sherif M. H. Sanad. (2022) New piperazine-based bis(thieno[2,3-b]pyridine) and bis(pyrazolo[3,4-b]pyridine) hybrids linked to benzofuran units: Synthesis and in vitro screening of potential acetylcholinesterase inhibitors. Synthetic Communications 52:6, pages 912-925.
Read now

Articles from other publishers (15)

Anindita Bhatta, Jahnabi Upadhyaya, Dipak Chamlagai, Lincoln Dkhar, Pynskhemborlang T. Phanrang, Mohan Rao Kollipara & Sivaprasad Mitra. (2024) Exploring the impact of novel thiazole-pyrazole fused benzo-coumarin derivatives on human serum albumin: Synthesis, photophysical properties, anti-cholinergic activity, and interaction studies. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 308, pages 123669.
Crossref
Mohamed S. Mohamed Ahmed, Ahmed E. M. Mekky & Sherif M. H. Sanad. (2023) Regioselective three-component synthesis and theoretical calculations of new alkane-linked bis(thiazol-2(3H)-imine) hybrids: a DFT-based FMO and local reactivity indices. Journal of the Iranian Chemical Society 20:10, pages 2527-2542.
Crossref
Rafaqat Hussain, Wajid Rehman, Shoaib Khan, Aneela Maalik, Mohamed Hefnawy, Ashwag S. Alanazi, Yousaf Khan & Liaqat Rasheed. (2023) Imidazopyridine-Based Thiazole Derivatives as Potential Antidiabetic Agents: Synthesis, In Vitro Bioactivity, and In Silico Molecular Modeling Approach. Pharmaceuticals 16:9, pages 1288.
Crossref
Tarik E. Ali, Mohammed A. Assiri, Maha N. Alqahtani, Ali. A. Shati, Mohammad. Y. Alfaifi & Serag. E. I. Elbehairi. (2023) Recyclization of morpholinochromonylidene–thiazolidinone using nucleophiles: facile synthesis, cytotoxic evaluation, apoptosis, cell cycle and molecular docking studies of a novel series of azole, azine, azepine and pyran derivatives. RSC Advances 13:27, pages 18658-18675.
Crossref
Sherif M.H. Sanad & Ahmed E.M. Mekky. (2023) New thieno[2,3-b]pyridine-fused pyrimidin-4(3H)-ones as potential thymidylate synthase inhibitors: Synthesis, SAR, in vitro and in silico study. Journal of Molecular Structure 1282, pages 135236.
Crossref
Inas G. Shahin, Khaled O. Mohamed, Azza T. Taher, Abdelrahman S. Mayhoub & Asmaa E. Kassab. (2023) Recent Advances in the Synthesis of Thiazole Ring: Mini Review. Mini-Reviews in Organic Chemistry 20:3, pages 270-284.
Crossref
Zeinab A. Abdallah, Sherif M. H. Sanad, Ahmed E. M. Mekky & Mohamed S. Mohamed Ahmed. (2023) New Arylazo‐Based (Chromene‐Thiazole) Hybrids as Potential MRSA Inhibitors. Chemistry & Biodiversity 20:4.
Crossref
Ahmed E. M. Mekky & Sherif M. H. Sanad. (2023) [3+2] Cycloaddition Synthesis of New Piperazine‐Linked Bis(chromene) Hybrids Possessing Pyrazole Units as Potential Acetylcholinesterase Inhibitors. Chemistry & Biodiversity 20:4.
Crossref
Ahmed E. M. Mekky & Sherif M. H. Sanad. (2022) [3+2] cycloaddition synthesis of new (nicotinonitrile‐chromene)‐based bis(pyrazole) hybrids as potential acetylcholinesterase inhibitors. Journal of Heterocyclic Chemistry 60:1, pages 156-160.
Crossref
Mohamed S. Mohamed Ahmed, Ahmed E.M. Mekky & Sherif M.H. Sanad. (2022) Regioselective [3 + 2] cycloaddition synthesis and theoretical calculations of new chromene-pyrazole hybrids: A DFT-based Parr Function, Fukui Function, local reactivity indexes, and MEP analysis. Journal of Molecular Structure 1267, pages 133583.
Crossref
Ahmed A. M. Ahmed, Ahmed E. M. Mekky & Sherif M. H. Sanad. (2022) New bis(pyrazolo[3,4-b]pyridines) and bis(thieno[2,3-b]pyridines) as potential acetylcholinesterase inhibitors: synthesis, in vitro and SwissADME prediction study. Journal of the Iranian Chemical Society 19:11, pages 4457-4471.
Crossref
Rafaqat Hussain, Hayat Ullah, Fazal Rahim, Maliha Sarfraz, Muhammad Taha, Rashid Iqbal, Wajid Rehman, Shoaib Khan, Syed Adnan Ali Shah, Sajjad Hyder, Majid Alhomrani, Abdulhakeem S. Alamri, Osama Abdulaziz & Mahmoud A. Abdelaziz. (2022) Multipotent Cholinesterase Inhibitors for the Treatment of Alzheimer’s Disease: Synthesis, Biological Analysis and Molecular Docking Study of Benzimidazole-Based Thiazole Derivatives. Molecules 27:18, pages 6087.
Crossref
Ahmed A. M. Ahmed, Ahmed E. M. Mekky & Sherif M. H. Sanad. (2021) Effective synthesis of new benzo-fused macrocyclic and heteromacrocyclic bis(Schiff bases). Journal of the Iranian Chemical Society 19:5, pages 1711-1722.
Crossref
Sherif M.H. Sanad, Ahmed E.M. Mekky & Tamer T. El-Idreesy. (2022) Potential bacterial biofilm, MRSA, and DHFR inhibitors based on new morpholine-linked chromene-thiazole hybrids: One-pot synthesis and in silico study. Journal of Molecular Structure 1248, pages 131476.
Crossref
Sherif M. H. Sanad & Ahmed E. M. Mekky. (2021) 3‐Aminopyrazolo[3,4‐ b ]pyridine: Effective Precursor for Barium Hydroxide‐Mediated Three Components Synthesis of New Mono‐ and Bis(pyrimidines) with Potential Cytotoxic Activity . Chemistry & Biodiversity 19:1.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.