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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 52, 2022 - Issue 8
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Articles

Green one-pot synthesis and in vitro antibacterial screening of pyrano[2,3-c]pyrazoles, 4H-chromenes and pyrazolo[1,5-a]pyrimidines using biocatalyzed pepsin

Nadia Hanafy MetwallyChemistry Department, Faculty of Science, Cairo University, Giza, EgyptCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-9706-3694
ORCID Icon,
Thoraya Hossam KoraaChemistry Department, Faculty of Science, Cairo University, Giza, Egypt
&
Sherif Mohamed Hamed SanadChemistry Department, Faculty of Science, Cairo University, Giza, EgyptORCID Iconhttps://orcid.org/0000-0002-0186-6418
ORCID Icon
Pages 1139-1154 | Received 22 Oct 2021, Published online: 25 May 2022

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Ahmed E. M. Mekky, Nariman A. S. Taha, Nada G. Mohammed, Fatma R. M. Hussein, Esraa H. Abdelfattah, Aya A. Gamal Eldin, Alshimaa A. M. Abdelsalam & Sherif M. H. Sanad. (2023) Development of pyrazolo[1,5-a]pyrimidine-based antibacterial agents. Synthetic Communications 53:13, pages 1053-1068.
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Sherif M. H. Sanad & Ahmed E. M. Mekky. (2023) Three-component regioselective synthesis and antibacterial evaluation of new arene-linked bis(pyrazolo[1,5-a]pyrimidine) hybrids. Synthetic Communications 53:9, pages 658-672.
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Ahmed E. M. Mekky & Sherif M. H. Sanad. (2022) Microwave-assisted synthesis of nicotinonitrile and/or arene-linked bis(chromene-thiazoles) as new VRE and MRSA inhibitors. Synthetic Communications 52:24, pages 2276-2290.
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Sherif M. H. Sanad & Ahmed E. M. Mekky. (2022) [3 + 2] Cycloaddition synthesis of new (nicotinonitrile-chromene) hybrids linked to pyrazole units as potential acetylcholinesterase inhibitors. Synthetic Communications 52:16, pages 1672-1684.
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Ahmed M. Abdelfattah, Ahmed E. M. Mekky & Sherif M. H. Sanad. (2022) Synthesis, antibacterial activity and in silico study of new bis(1,3,4-oxadiazoles). Synthetic Communications 52:11-12, pages 1421-1440.
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Articles from other publishers (11)

Saba Farooq & Zainab Ngaini. (2024) Recent Synthesis of Mono‐ & Bis‐Pyranopyrazole Derivatives. ChemistrySelect 9:8.
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Abdou K. Allayeh, Aliaa H. El-boghdady, Mohamed A. Said, Mahmoud G. A. Saleh, Mohammed T. Abdel-Aal & Mohamed G. Abouelenein. (2024) Discovery of Pyrano[2,3-c]pyrazole Derivatives as Novel Potential Human Coronavirus Inhibitors: Design, Synthesis, In Silico, In Vitro, and ADME Studies. Pharmaceuticals 17:2, pages 198.
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Ashok R. Yadav, Ashishkumar P. Katariya, Anant B. Kanagare, Pramod D. Jawale Patil, Chandrakant K. Tagad, Satish A. Dake, Pratik A. Nagwade & Satish U. Deshmukh. (2024) Review on advancements of pyranopyrazole: synthetic routes and their medicinal applications. Molecular Diversity.
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Ahmed A. M. Ahmed, Ahmed E. M. Mekky & Sherif M. H. Sanad. (2023) Three‐component synthesis of arene‐linked pyrazolo[1,5‐ a ]pyrimidines . Journal of Heterocyclic Chemistry 60:10, pages 1815-1821.
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Ahmed E. M. Mekky & Sherif M. H. Sanad. (2023) Synthesis of New Pyrazolo[1,5‐ a ]pyrimidines as Potential Antibacterial Agents: In Vitro and In Silico Study . ChemistrySelect 8:17.
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Ahmed E. M. Mekky & Sherif M. H. Sanad. (2023) Antibacterial screening of new bis(pyrazolo[1,5-a]pyrimidine) hybrids linked to different spacers. Mendeleev Communications 33:3, pages 331-333.
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Liang-liang Chi, Lin-lin Hao, Zhi-qiang Cai, Du-lin Kong, Ya-nan Wang, Wei-tao Qin, Yang Gao & Zhi-zhuo Qu. (2023) Design, Synthesis, and Biological Evaluation of Novel Pyrazolo[1,5-a]pyrimidine and 1,3-Benzodiazine Derivatives as Potent Antitumor Agents. Russian Journal of General Chemistry 92:12, pages 2698-2707.
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Mohamed S. Mohamed Ahmed, Ahmed E.M. Mekky & Sherif M.H. Sanad. (2022) Regioselective [3 + 2] cycloaddition synthesis and theoretical calculations of new chromene-pyrazole hybrids: A DFT-based Parr Function, Fukui Function, local reactivity indexes, and MEP analysis. Journal of Molecular Structure 1267, pages 133583.
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Mohamed M. Hammouda, Hatem E. Gaffer & Khaled M. Elattar. (2022) Insights into the medicinal chemistry of heterocycles integrated with a pyrazolo[1,5- a ]pyrimidine scaffold . RSC Medicinal Chemistry 13:10, pages 1150-1196.
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Sherif M. H. Sanad, Ahmed E. M. Mekky & Ahmed A. M. Ahmed. (2022) Tandem synthesis, cytotoxicity, and in silico study of new 1,3,4‐oxadiazoles as potential thymidylate synthase inhibitors. Archiv der Pharmazie 355:10.
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Ahmed E. M. Mekky, Tamer T. El‐Idreesy & Sherif M. H. Sanad. (2022) Chloramine Trihydrate‐Mediated Tandem Synthesis of New Pyrrole and/or Arene‐Linked Mono‐ and Bis(1,3,4‐Oxadiazole) Hybrids as Potential Bacterial Biofilm and MRSA Inhibitors. Chemistry & Biodiversity 19:8.
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