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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 9, 1979 - Issue 8
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Original Articles

A Convenient Synthesis of 2-Substituted 3-Hydroxy- and 3-Amino-Thiophens from Derivatives of 2-Chloroacrylic Acid

Patrick R Huddleston Department of Physical Sciences, Trent Polytechnic, Burton Street, Nottingham, NG1 4BU, England
&
John M. Barker Department of Physical Sciences, Trent Polytechnic, Burton Street, Nottingham, NG1 4BU, England
Pages 731-734 | Received 04 May 1979, Published online: 05 Dec 2006

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Batchu Chandrasekhar. (2008) β-Mercaptoalkanoic carboxylic esters: versatile synthons in heterocyclic chemistry . Journal of Sulfur Chemistry 29:2, pages 187-240.
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John M. Barker, Patrick R. Huddleston & Michael L. Wood. (2002) A RAPID CONVERSION OF 3-OXOTHIOLANES INTO 3-AMINOTHIOPHENES. Synthetic Communications 32:16, pages 2565-2568.
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Claude Paulmier. (1996) Synthesis and Reactivity of 3-Aminothiophenes and 3,4-Diaminothiophenes. Sulfur reports 19:1, pages 215-284.
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R. Donoso, P. Jordan de Urries & J. Lissavetzky. (1996) A NEW ROUTE FOR THE SYNTHESIS OF 3-(3-THIENYLOXY)-1,2-PROPANEDIOLS AND 3-(3-THIENYLOXY)-1,2-EPOXYPROPANES. Organic Preparations and Procedures International 28:4, pages 453-462.
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YolanteZ. Adamczewska, JohnM. Barker, PatrickR. Huddleston & MichaelL. Wood. (1996) A Synthesis of 2-ACYL- 3-Hydroxythiophenes. Synthetic Communications 26:6, pages 1083-1096.
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V.P. Litvinov, Yu.A. Sharanin & F.S. Babichev. (1986) Cyclization of Nitriles as Synthetic Route to 2-and 3-Aminothiophenes. Sulfur reports 6:2, pages 97-128.
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C. Corral, J. Lissavetzky, A.S. Alvarez-Insúa & A.M. Valdeolmillos. (1985) SYNTHESIS OF 3-MERCAPTOTHIOPHENE-2-AND 4-CARBOXYLIC ACIDS. Organic Preparations and Procedures International 17:3, pages 163-167.
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Yaping Tao, Ligang Han, Andong Sun, Kexi Sun, Qian Zhang, Wanqiang Liu, Jianbin Du & Zhaojun Liu. (2020) Crystal Structure and Computational Study on Methyl-3-Aminothiophene-2-Carboxylate. Crystals 10:1, pages 19.
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Massimo Pregnolato, Pietro Borgna & Marco Terreni. (2009) Synthesis of 3 H ‐thieno[3,2‐ c ]‐1,2‐dithiole‐3‐thione and its reaction with n ‐butylamine . Journal of Heterocyclic Chemistry 32:3, pages 847-850.
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V. Darias, L. Bravo, S. S. Abdallah, C. C. Sánchez Mateo, M. A. Expósito‐orta, J. Lissavetsky & J. Manzanares. (2006) Synthesis and Preliminary Pharmacological Study of Thiophene Analogues of the Antipyretic and Analgesic Agent Ethenzamide. Archiv der Pharmazie 325:2, pages 83-87.
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P. R. HUDDLESTON & J. M. BARKER. (2016) ChemInform Abstract: A CONVENIENT SYNTHESIS OF 2‐SUBSTITUTED 3‐HYDROXY‐ AND 3‐AMINOTHIOPHENES FROM DERIVATIVES OF 2‐CHLOROACRYLIC ACID. Chemischer Informationsdienst 11:9.
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