Publication Cover
Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 15, 1985 - Issue 7
187
Views
32
CrossRef citations to date
0
Altmetric
Original Articles

Synthetic Routes to Chiral 3-Pyrrolidinols

, &
Pages 587-598 | Published online: 05 Dec 2006

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

Thomas Mehler, Jürgen Martens & Sabine Wallbaum. (1993) Enantioselective Addition of Diethylzinc to Aromatic Aldehydes Catalysed by Chiral Ligands Derived from L-Hydroxyproline. Synthetic Communications 23:19, pages 2691-2699.
Read now
BruceD. Harris, KrishnaL. Bhat & MadeleineM. Joullié. (1986) Synthesis of 3S-Pyrrolidinol from L-Glutamic Acid. Synthetic Communications 16:14, pages 1815-1822.
Read now

Articles from other publishers (29)

Maëva M. Pichon, Fabien Stauffert, Luis G. Addante-Moya, Anne Bodlenner & Philippe Compain. (2018) Metal-Free Iodine-Mediated Deoxygenation of Alcohols in the Position α to Electron-Withdrawing Groups. European Journal of Organic Chemistry 2018:13, pages 1538-1545.
Crossref
Pei-Qiang Huang, Hui Geng, Yong-Song Tian, Qiu-Ran Peng & Kai-Jiong Xiao. (2015) The first enantioselective total synthesis of (+)-preussin B and an improved synthesis of (+)-preussin by step-economical methods. Science China Chemistry 58:3, pages 478-482.
Crossref
Gregor Schwan, Ghadir Barbar Asskar, Norbert Höfgen, Lenka Kubicova, Uta Funke, Ute Egerland, Michael Zahn, Karen Nieber, Matthias Scheunemann, Norbert Sträter, Peter Brust & Detlef Briel. (2014) Fluorine-Containing 6,7-Dialkoxybiaryl-Based Inhibitors for Phosphodiesterase 10 A: Synthesis and in vitro Evaluation of Inhibitory Potency, Selectivity, and Metabolism. ChemMedChem 9:7, pages 1476-1487.
Crossref
Elisabete P. Carreiro, Patrícia Louro, Gizé Adriano, Romina A. Guedes, Nicholas Vannuchi, Ana R. Costa, Célia M.M. Antunes, Rita C. Guedes & A.J. Burke. (2014) 3-Hydroxypyrrolidine and (3,4)-dihydroxypyrrolidine derivatives: Inhibition of rat intestinal α-glucosidase. Bioorganic Chemistry 54, pages 81-88.
Crossref
Xiao-Gang Wang, Ai-E Wang, Yi Hao, Yuan-Ping Ruan & Pei-Qiang Huang. (2013) Modular Enantioselective Synthesis of 8-Aza-prostaglandin E 1 . The Journal of Organic Chemistry 78:18, pages 9488-9493.
Crossref
Mushtaq A. Aga, Brijesh Kumar, Abdul Rouf, Bhahwal A. Shah, Samar S. Andotra & Subhash C. Taneja. (2013) Natural (−)‐Vasicine as a Novel Source of Optically Pure 1‐Benzylpyrrolidin‐3‐ol. Helvetica Chimica Acta 96:5, pages 969-977.
Crossref
Jin-Li Zheng, Hui Liu, Yu-Feng Zhang, Wei Zhao, Jin-Shuan Tong, Yuan-Ping Ruan & Pei-Qiang Huang. (2011) A study on the racemization step in the synthesis of pyrrolidinols via cyclic α-hydroxyimides. Tetrahedron: Asymmetry 22:3, pages 257-263.
Crossref
Masao Morimoto, Kazumi Tamura, Kanji Nagai & Eiji Yashima. (2010) Chirality sensing of chiral pyrrolidines and piperazines with a liquid crystalline dynamic helical poly(phenylacetylene) bearing ethyl phosphonate pendant groups. Journal of Polymer Science Part A: Polymer Chemistry 48:6, pages 1383-1390.
Crossref
Daniel P. Pienaar, Robin K. Mitra, Thomas I. van Deventer & Adriana L. Botes. (2008) Synthesis of a variety of optically active hydroxylated heterocyclic compounds using epoxide hydrolase technology. Tetrahedron Letters 49:48, pages 6752-6755.
Crossref
Masao Morimoto & Kenichi Sakai. (2008) Practical synthetic process for enantiopure 1-benzyl-3-hydroxypyrrolidine. Tetrahedron: Asymmetry 19:12, pages 1465-1469.
Crossref
Mathieu Toumi, François Couty & Gwilherm Evano. (2008) A practical route to enantiopure 3-hydroxy-pyrrolidines: application to a straightforward synthesis of (−)-bulgecinine. Tetrahedron Letters 49:7, pages 1175-1179.
Crossref
Miguel Yus, Francisco Foubelo, Mohamed Medjahdi & José C. González-Gómez. (2008) Stereoselective Synthesis of Pyrrolidin-3-ols from Homoallylamines. HETEROCYCLES 76:1, pages 569.
Crossref
Dominik Rejman, Petr Kočalka, Miloš Buděšínský, Radek Pohl & Ivan Rosenberg. (2007) Synthesis of diastereomeric 3-hydroxy-4-pyrrolidinyl derivatives of nucleobases. Tetrahedron 63:5, pages 1243-1253.
Crossref
Petr Kočalka, Radek Pohl, Dominik Rejman & Ivan Rosenberg. (2006) Synthesis of racemic and enantiomeric 3-pyrrolidinyl derivatives of nucleobases. Tetrahedron 62:24, pages 5763-5774.
Crossref
Zhi Li, Hans-Jürgen Feiten, Dongliang Chang, Wouter A. Duetz, Jan B. van Beilen & Bernard Witholt. (2001) Preparation of ( R )- and ( S )- N -Protected 3-Hydroxypyrrolidines by Hydroxylation with Sphingomonas sp. HXN-200, a Highly Active, Regio- and Stereoselective, and Easy to Handle Biocatalyst . The Journal of Organic Chemistry 66:25, pages 8424-8430.
Crossref
Juan C. Jaen. 2001. Encyclopedia of Reagents for Organic Synthesis. Encyclopedia of Reagents for Organic Synthesis.
Zhi Li, Hans-Jürgen Feiten, Jan B van Beilen, Wouter Duetz & Bernard Witholt. (1999) Preparation of optically active N-benzyl-3-hydroxypyrrolidine by enzymatic hydroxylation. Tetrahedron: Asymmetry 10:7, pages 1323-1333.
Crossref
Yutaka Aoyagi & Robert M. Williams. (1998) Asymmetric synthesis of 1-Boc-3- and 4-hydroxypyrrolidines. Tetrahedron 54:43, pages 13045-13058.
Crossref
Aline Corruble, Jean-Yves Valnot, Jacques Maddaluno & Pierre Duhamel. (1997) 3-Aminopyrrolidine lithium amide in enantioselective addition of organolithium compounds onto aromatic aldehydes. Tetrahedron: Asymmetry 8:10, pages 1519-1523.
Crossref
Ulrich Nagel & Hans Günter Nedden. (2006) Enantioselective Catalysis, XIII. Preparative and Structural Chemistry of Chiral 3‐(Diphenylphosphanyl)‐pyrrolidiens and Their Palladium(II) Complexes. Chemische Berichte 130:3, pages 385-398.
Crossref
Hiroshi Tomori, Kuniko Shibutani & Katsuyuki Ogura. (1996) Lipase-Catalyzed Practical Synthesis of ( R )-1-Benzyl-3-hydroxy-2,5-pyrrolidinedione and Its Related Compounds . Bulletin of the Chemical Society of Japan 69:1, pages 207-215.
Crossref
Victor Fadij, Edward A. LenoirIIIIII, Mark J. Suto, James R. Zeller & James Wemple. (1994) An efficient method for the synthesis of (R)-3-(1-amino-1-methylethyl)pyrrolidines for the antiinfective agent, PD 138312. Tetrahedron: Asymmetry 5:7, pages 1131-1134.
Crossref
R. Gottschlich, K.A. Ackermann, A. Barber, G.D. Bartoszyk & H.E. Greiner. (1994) EMD 61 753 as a favourable representative of structurally novel arylacetamido-type K opiate receptor agonists. Bioorganic & Medicinal Chemistry Letters 4:5, pages 677-682.
Crossref
Jacques Maddaluno, Aline Corruble, Valéric Leroux, Gérard Plé & Pierre Duhamel. (1992) Handy access to chiral N,N′-disubstituted 3-aminopyrrolidines.. Tetrahedron: Asymmetry 3:10, pages 1239-1242.
Crossref
David L. Hughes. 2004. Organic Reactions. Organic Reactions 335 656 .
Wim-Jan Koot, Roel van Ginkel, Mirko Kranenburg, Henk Hiemstra, Saskia Louwrier, Marinus J. Moolenaar & W.Nico Speckamp. (1991) Synthesis of statine from (S)-malic acid; stereocontrol via radical cyclization. Tetrahedron Letters 32:3, pages 401-404.
Crossref
Hideki Arima, Kazuharu Tamazawa & Makoto Takeuchi. (2006) Synthesis of 14 C‐ and 2 H‐labeled (3S)‐1‐benzyl‐3‐pyrrolidinyl methyl (4S)‐2,6‐dimethyl‐4‐( m ‐nitrophenyl)‐1,4‐dihydropyridine‐3,5‐dicarboxylate hydrochloride (YM‐09730‐5), a potent calcium antagonist . Journal of Labelled Compounds and Radiopharmaceuticals 25:2, pages 161-170.
Crossref
Derek H.R. Barton, Yolande Hervé, Pierre Potier & Josiane Thierry. (1988) Manipulation of the cabboxyl groups of α-amino-acids and peptides using radical chemistry based on esters of -hydroxy-2-thiopyridone. Tetrahedron 44:17, pages 5479-5486.
Crossref
K. L. BHAT, D. M. FLANAGAN & M. M. JOULLIE. (2016) ChemInform Abstract: SYNTHETIC ROUTES TO CHIRAL 3‐PYRROLIDINOLS. Chemischer Informationsdienst 16:46.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.