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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 18, 1988 - Issue 2
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Original Articles

Synthesis of New Epiminoisopentenoids

Edward J. Parish Department of Chemistry, Auburn University, AL, 36849
&
W. David Nes Plant and Fungal Lipid Group Plant Development and Productivity Research Unit ARS/U. S., Department of Agriculture, Albany, CA, 94710
Pages 221-226 | Published online: 19 Dec 2006

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Juan B. Rodriguez, Bruno N. Falcone & Sergio H. Szajnman. (2016) Detection and treatment of Trypanosoma cruzi: a patent review (2011-2015). Expert Opinion on Therapeutic Patents 26:9, pages 993-1015.
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De-an Guo & W. David Nes. (1995) Synthesis of a Rationally Designed Inhibitor of the (S)-Adenosyl-L-Methionine: △24(25)-Sterol Methyl Transferase. Synthetic Communications 25:17, pages 2623-2630.
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Han-Wel Chang, Michael E. Friedman, Deborah L. Hileman & Edward J. Parish. (1993) Inhibition of Human Synovial β-Glucuronidase by Steroidal Compounds. Journal of Enzyme Inhibition 6:4, pages 331-335.
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Articles from other publishers (27)

David Leaver. (2018) Synthesis and Biological Activity of Sterol 14α-Demethylase and Sterol C24-Methyltransferase Inhibitors. Molecules 23:7, pages 1753.
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Medhanie E. Kidane, Boden H. Vanderloop, Wenxu Zhou, Crista D. Thomas, Emilio Ramos, Ujjal Singha, Minu Chaudhuri & W. David Nes. (2017) Sterol methyltransferase a target for anti-amoeba therapy: towards transition state analog and suicide substrate drug design. Journal of Lipid Research 58:12, pages 2310-2323.
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Hossein Mehrabi. (2009) Synthesis of both isomers of aziridine derived from the mixture of cis - and trans -limonene oxide . Canadian Journal of Chemistry 87:8, pages 1117-1121.
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Claudia Maia, Márcia Attias, Julio Urbina, Ian Gilbert, Filippo Magaraci & Wanderley de Souza. (2007) Azasterols impair Giardia lamblia proliferation and induces encystation. Biochemical and Biophysical Research Communications 363:2, pages 310-316.
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Alfred Hassner, Lavinia Marinescu & Mikael Bols. 2001. Encyclopedia of Reagents for Organic Synthesis. Encyclopedia of Reagents for Organic Synthesis.
Lucas Dantas-Leite, Julio A. Urbina, Wanderley de Souza & Rossiane C. Vommaro. (2005) Antiproliferative synergism of azasterols and antifolates against Toxoplasma gondii. International Journal of Antimicrobial Agents 25:2, pages 130-135.
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Ragu Kanagasabai, Wenxu Zhou, Jialin Liu, Thi Thuy Minh Nguyen, Phani Veeramachaneni & W. David Nes. (2004) Disruption of ergosterol biosynthesis, growth, and the morphological transition in Candida albicans by sterol methyltransferase inhibitors containing sulfur at C‐25 in the sterol side chain . Lipids 39:8, pages 737-746.
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Lucas Dantas-Leite, Julio A Urbina, Wanderley de Souza & Rossiane C Vommaro. (2004) Selective anti-Toxoplasma gondii activities of azasterols. International Journal of Antimicrobial Agents 23:6, pages 620-626.
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Chad E. Davis, Jessica L. Bailey, Jonathan W. Lockner & Robert M. Coates. (2002) Regio- and Stereoselectivity of Diethylaluminum Azide Opening of Trisubstituted Epoxides and Conversion of the 3° Azidohydrin Adducts to Isoprenoid Aziridines. The Journal of Organic Chemistry 68:1, pages 75-82.
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Alfred Hassner. 2001. Encyclopedia of Reagents for Organic Synthesis. Encyclopedia of Reagents for Organic Synthesis.
Andreı́na Liendo, Gonzalo Visbal, Marta M. Piras, Romano Piras & Julio A. Urbina. (1999) Sterol composition and biosynthesis in Trypanosoma cruzi amastigotes. Molecular and Biochemical Parasitology 104:1, pages 81-91.
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Ali Koohang, Corey L. Stanchina & Robert M. Coates. (1999) Regio- and stereoselective synthesis of N-H aziridines N-N bond reduction ofN-quinazolinylaziridines. Tetrahedron 55:32, pages 9669-9686.
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Jürgen O. Metzger & Sandra Fürmeier. (1999) New Type of Skipped Oligoaziridines: Synthesis of New Fatty AcidDerivatives Containing Aziridine Functions. European Journal of Organic Chemistry 1999:3, pages 661-664.
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Edna S. Kaneshiro, Zunika Amit, Mardie M. Swonger, George P. Kreishman, Elwood E. Brooks, Mara Kreishman, Koka Jayasimhulu, Edward J. Parish, Hang Sun, Stephen A. Kizito & David H. Beach. (1999) Pneumocysterol [(24 Z )-ethylidenelanost-8-en-3β-ol], a rare sterol detected in the opportunistic pathogen Pneumocystis carinii hominis : Structural identity and chemical synthesis . Proceedings of the National Academy of Sciences 96:1, pages 97-102.
Crossref
Edward J. Parish, Nida Aksara & Terrence L. Boos. (1997) Remote functionalization of the steroid side‐chain. Lipids 32:12, pages 1325-1330.
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J A Urbina, G Visbal, L M Contreras, G McLaughlin & R Docampo. (1997) Inhibitors of delta24(25) sterol methyltransferase block sterol synthesis and cell proliferation in Pneumocystis carinii. Antimicrobial Agents and Chemotherapy 41:7, pages 1428-1432.
Crossref
Lellys Mariela Contreras, Julio Vivas & Julio A. Urbina. (1997) Altered lipid composition and enzyme activities of plasma membranes from Trypanosoma (Schizotrypanum) Cruzi epimastigotes grown in the presence of sterol biosynthesis inhibitors. Biochemical Pharmacology 53:5, pages 697-704.
Crossref
Julio Vivas, Julio A. Urbina & Wanderley de Souza. (1996) Ultrastructural alterations in Trypanosoma (Schizotrypanum) cruzi induced by Δ24(25) sterol methyl transferase inhibitors and their combinations with ketoconazole. International Journal of Antimicrobial Agents 7:4, pages 235-240.
Crossref
. 1996. Comprehensive Heterocyclic Chemistry II. Comprehensive Heterocyclic Chemistry II 1215 1369 .
Kuriya Madavu Lokanatha Rai & Alfred Hassner. 1996. Comprehensive Heterocyclic Chemistry II. Comprehensive Heterocyclic Chemistry II 61 96 .
Julio A. Urbina, Julio Vivas, Gonzalo Visbal & Lellys M. Contreras. (1995) Modification of the sterol composition of Trypanosoma (Schizotrypanum) cruzi epimastigotes by Δ24(25)-sterol methyl transferase inhibitors and their combinations with ketoconazole. Molecular and Biochemical Parasitology 73:1-2, pages 199-210.
Crossref
G.G. Janssen & W.D. Nes. (1992) Structural requirements for transformation of substrates by the S-adenosyl-L-methionine:delta 24(25)-sterol methyltransferase. Inhibition by analogs of the transition state coordinate.. Journal of Biological Chemistry 267:36, pages 25856-25863.
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W. David Nes, Phu Le, Eugene E. van Tamelen & Eric J. Leopold. (1990) Presqualene alcohol, squalene, and sterol biosynthesis from bifarnesol. Experimental Mycology 14:1, pages 74-77.
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W. David Nes. 1990. Biochemistry of the Mevalonic Acid Pathway to Terpenoids. Biochemistry of the Mevalonic Acid Pathway to Terpenoids 283 327 .
W.David Nes, Sihua Xu & Edward J. Parish. (1989) Metabolism of 24(R,S),25-epiminolanosterol to 25-aminolanosterol and lanosterol by Gibberella fujikuroi. Archives of Biochemistry and Biophysics 272:2, pages 323-331.
Crossref
G Popják, A Meenan, E J Parish & W D Nes. (1989) Inhibition of Cholesterol Synthesis and Cell Growth by 24(R, S),25-Iminolanosterol and Triparanol in Cultured Rat Hepatoma Cells. Journal of Biological Chemistry 264:11, pages 6230-6238.
Crossref
W. David Nes & Edward J. Parish. (1988) Metabolism of 2( RS ),3‐epiminosqualene to 24( RS ),25‐epiminolanosterol by Gibberella fujikuroi . Lipids 23:4, pages 375-376.
Crossref

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