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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 24, 1994 - Issue 8
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Original Articles

An Efficient Synthesis of 4-Aryl-1,2,3,4-Tetrahydroisoquinolines

R. Bryan Miller Department of Chemistry, University of California, Davis Davis, CA, 95616
&
John J. Svoboda Department of Chemistry, University of California, Davis Davis, CA, 95616
Pages 1187-1193 | Received 10 Aug 1993, Published online: 23 Sep 2006

Citations (15)

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Xumiao Zhao & Xiuying Wan. (1995) A PRACTICAL SYNTHESIS OF 4-(3′,4-DIHYDROXYLPHENYL)-1,2,3,4-TETRAHYDROKOQUINOLINE. Organic Preparations and Procedures International 27:4, pages 513-516.
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Articles from other publishers (14)

Sabyasachi Manna & Kandikere Ramaiah Prabhu. (2019) Visible-Light-Mediated Direct Decarboxylative Acylation of Electron-Deficient Heteroarenes Using α-Ketoacids. The Journal of Organic Chemistry 84:9, pages 5067-5077.
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Larry Yet. 2018. Privileged Structures in Drug Discovery. Privileged Structures in Drug Discovery 356 413 .
Tummanapalli Satyanarayana, Parthasarathy Muthuraman, Dhanunjaya Naidu Vangapandu & Supriyo Majumder. (2014) Scandium(III) triflate mediated intramolecular ring expansion of aziridines: a direct access to 4-aryltetrahydroisoquinolines. Tetrahedron Letters 55:50, pages 6787-6790.
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Sudipta Kumar Manna & Gautam Panda. (2014) Synthesis of enantiomerically enriched indolines and tetrahydroisoquinolines from (S)-amino acid-derived chiral carbocations: an easy access to (3S,4R)-demethoxy-3-isopropyl diclofensine. Org. Biomol. Chem. 12:41, pages 8318-8324.
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Kamal Nain Singh, Paramjit Singh, Pushpinder Singh & Yadwinder Singh Deol. (2012) Nucleophilic Addition of β-Amino Carbanions to Arynes: One-Pot Synthesis of 4-Aryl- N -methyl-1,2,3,4-tetrahydroisoquinolines . Organic Letters 14:9, pages 2202-2205.
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Min Hu, Peter R. Guzzo, Congxiang Zha, Kassoum Nacro, Yuh-Lin Yang, Carla Hassler & Shuang Liu. (2012) A facile synthesis of 4-aryl-1,2,3,4-tetrahydroisoquinolines. Tetrahedron Letters 53:7, pages 846-848.
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I. Yu. Chernyshov, V. V. Levin, A. D. Dilman, P. A. Belyakov, M. I. Struchkova & V. A. Tartakovsky. (2011) Synthesis of CF3-substituted 1,2,3,4-tetrahydroisoquinolines and 1,2,3,6-tetrahydropyridines. Russian Chemical Bulletin 59:11, pages 2102-2107.
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John M. Keith, Leslie A. Gomez, Ronald L. Wolin, Ann J. Barbier, Sandy J. Wilson, Jamin D. Boggs, Curt Mazur, Ian C. Fraser, Brian Lord, Leah Aluisio, Timothy W. Lovenberg & Nicholas I. Carruthers. (2007) Pyrrolidino-tetrahydroisoquinolines as potent dual H3 antagonist and serotonin transporter inhibitors. Bioorganic & Medicinal Chemistry Letters 17:9, pages 2603-2607.
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Kamal M. Dawood & Andreas Kirschning. (2005) Combining enabling techniques in organic synthesis: solid-phase-assisted catalysis under microwave conditions using a stable Pd(II)-precatalyst. Tetrahedron 61:51, pages 12121-12130.
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Julio A. Seijas, M. Pilar Vázquez-Tato, M. Montserrat Martínez & Moacir G. Pizzolatti. (2005) Oxazoline as a useful tool in organic synthesis: preparation of 4-aryl-1,2,3,4-tetrahydroisoquinoline alkaloid skeleton. Tetrahedron Letters 46:35, pages 5827-5830.
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Somsak Ruchirawat, Sopchok Tontoolarug & Poolsak Sahakitpichan. (2001) Synthesis of 4-Aryltetrahydroiso-quinolines: Application to the Synthesis of Cherylline. HETEROCYCLES 55:4, pages 635.
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Axel Couture, Eric Deniau, Pierre Grandclaudon & Patrice Woisel. (1996) A new synthetic route to 2-alkyl-4-aryl-1(2H)-isoquinolones and 2-alkyl-4-aryl-1,2,3,4-tetrahydroisoquinolines. Tetrahedron 52:12, pages 4433-4448.
Crossref
Martin G. Banwell, Brett D. Bissett, Stefan Busato, Cameron J. Cowden, David C. R. Hockless, Jeffrey W. Holman, Roger W. Read & Angela W. Wu. (1995) Trifluoromethanesulfonic anhydride–4-(N,N-dimethylamino)pyridine as a reagent combination for effecting Bischler–Napieraiski cyclisation under mild conditions: application to total syntheses of the Amaryllidaceae alkaloids N-methylcrinasiadine, anhydrolycorinone, hippadine and oxoassoanine. J. Chem. Soc., Chem. Commun.:24, pages 2551-2553.
Crossref
R. B. MILLER & J. J. SVOBODA. (2010) ChemInform Abstract: An Efficient Synthesis of 4‐Aryl‐1,2,3,4‐tetrahydroisoquinolines (VI)‐( VIII).. ChemInform 25:43.
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