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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 25, 1995 - Issue 14
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Original Articles

Two Step Synthesis of Substituted Indolo[1,2-a]-Quinoxalin-6-Ones

Michael J. Beach The R. W. Johnson Pharmaceutical Research Institute 1000 Route 202, Raritan, New Jersey, 08869-0602, USA
,
Ruby Hope The R. W. Johnson Pharmaceutical Research Institute 1000 Route 202, Raritan, New Jersey, 08869-0602, USA
,
Dieter H. Klaubert The R. W. Johnson Pharmaceutical Research Institute 1000 Route 202, Raritan, New Jersey, 08869-0602, USA
&
Ronald K. Russell The R. W. Johnson Pharmaceutical Research Institute 1000 Route 202, Raritan, New Jersey, 08869-0602, USA
Pages 2165-2183 | Received 31 Oct 1994, Published online: 23 Sep 2006

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Vanessa Desplat, Stéphane Moreau, Solene Belisle-Fabre, Denis Thiolat, Juliette Uranga, Romain Lucas, Laure de Moor, Stéphane Massip, Christian Jarry, Djavad M. Mossalayi, Pascal Sonnet, Gérard Déléris & Jean Guillon. (2011) Synthesis and evaluation of the antiproliferative activity of novel isoindolo[2,1-a]quinoxaline and indolo[1,2-a]quinoxaline derivatives. Journal of Enzyme Inhibition and Medicinal Chemistry 26:5, pages 657-667.
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Vanessa Desplat, Stephane Moreau, Aurore Gay, Solene Belisle Fabre, Denis Thiolat, Stephane Massip, Gregory Macky, Frederic Godde, Djavad Mossalayi, Christian Jarry & Jean Guillon. (2010) Synthesis and evaluation of the antiproliferative activity of novel pyrrolo[1,2-a]quinoxaline derivatives, potential inhibitors of Akt kinase. Part II. Journal of Enzyme Inhibition and Medicinal Chemistry 25:2, pages 204-215.
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Maddirala Shambabu Joseph & L. D. Basanagoudar. (2003) Synthesis of Substituted Indolo[1,2- ]quinoxalines. Synthetic Communications 33:5, pages 851-862.
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Articles from other publishers (17)

Qian Gao, Jia-Ming Lu, Lingyun Yao, Siqi Wang, Jun Ying & Xiao-Feng Wu. (2020) Cobalt-Catalyzed Direct C–H Carbonylative Synthesis of Free ( NH )-Indolo[1,2- a ]quinoxalin-6(5 H )-ones . Organic Letters 23:1, pages 178-182.
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Qiu-Chao Mu, Yi-Xue Nie, Xing-Feng Bai, Jing Chen, Lei Yang, Zheng Xu, Li Li, Chun-Gu Xia & Li-Wen Xu. (2019) Tertiary amine-directed and involved carbonylative cyclizations through Pd/Cu-cocatalyzed multiple C–X (X = H or N) bond cleavage. Chemical Science 10:40, pages 9292-9301.
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Vakhid A. Mamedov, Elena A. Khafizova, Anastasiya I. Zamaletdinova, Julia K. Voronina, Saniya F. Kadyrova, Ekaterina V. Mironova, Dmitry B. Krivolapov, Ildar Kh. Rizvanov & Oleg G. Sinyashin. (2017) A New Method for the Synthesis of Substituted 8,9,10,11-Tetrahydroindolo[1,2-a]Quinoxalin-6(5H)-Ones. Chemistry of Heterocyclic Compounds 53:5, pages 560-567.
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Jun Fang & Chao-Guo Yan. (2016) Convenient Synthesis of Functionalized 3,4,10,11-tetrahydroindolo[1,2-a]Quinoxalines Via Three-component Reaction of Dimedone, 3-nitrochromenes and Ammonium Acetate. Journal of Heterocyclic Chemistry 53:3, pages 800-804.
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Anupal Gogoi, Prasenjit Sau, Wajid Ali, Srimanta Guin & Bhisma K. Patel. (2016) Copper(II)-Catalyzed Synthesis of ­Indoloquinoxalin-6-ones through Oxidative Mannich Reaction. European Journal of Organic Chemistry 2016:7, pages 1449-1453.
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Saeed Balalaie, Morteza Bararjanian, Saeedeh Hosseinzadeh, Frank Rominger, Hamid Reza Bijanzadeh & Eckardt Wolf. (2011) Designing a sequential Ugi/Ullmann type reaction for the synthesis of indolo[1,2-a]quinoxalinones catalyzed by CuI/l-proline. Tetrahedron 67:38, pages 7294-7300.
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Jean Guillon, Elisabeth Mouray, Stéphane Moreau, Catherine Mullié, Isabelle Forfar, Vanessa Desplat, Solene Belisle-Fabre, Noël Pinaud, François Ravanello, Augustin Le-Naour, Jean-Michel Léger, Grace Gosmann, Christian Jarry, Gérard Déléris, Pascal Sonnet & Philippe Grellier. (2011) New ferrocenic pyrrolo[1,2-a]quinoxaline derivatives: Synthesis, and in vitro antimalarial activity – Part II. European Journal of Medicinal Chemistry 46:6, pages 2310-2326.
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Michael D. Wendt & Aaron R. Kunzer. (2010) Ortho selectivity in SNAr substitutions of 2,4-dihaloaromatic compounds. Reactions with piperidine. Tetrahedron Letters 51:4, pages 641-644.
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Gregory L. Frayne & Gary M. Green. (2008) Investigation of the N-arylation of various substituted indoles using microwave-assisted technology. Tetrahedron Letters 49:51, pages 7328-7329.
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Cherukupally Praveen, Javvaji Rama Rao, Padi Pratap Reddy, Kaga Mukkanti & Gade Srinivas Reddy. (2009) Facile synthesis of 6‐aryl‐5 H ‐8‐oxa‐4 b , 7‐diaza‐benzo[ a ]azulen‐9‐one derivatives, new tricyclic heterocycles . Journal of Heterocyclic Chemistry 45:4, pages 1083-1087.
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Bang-Chi Chen, Rulin Zhao, Mark S. Bednarz, Bei Wang, Joseph E. Sundeen & Joel C. Barrish. (2004) A New Strategy for the Construction of the Imidazo[1,5- a ]quinoxalin-4-one Ring System and Its Application to the Efficient Synthesis of BMS-238497, a Novel and Potent Lck Inhibitor . The Journal of Organic Chemistry 69:3, pages 977-979.
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Giorgio Abbiati, Egle M. Beccalli, Gianluigi Broggini & Caterina Zoni. (2003) Regioselectivity on the Palladium-Catalyzed Intramolecular Cyclization of Indole Derivatives. The Journal of Organic Chemistry 68:20, pages 7625-7628.
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Roberto Chicharro, Sonia de Castro, José L. Reino & Vicente J. Arán. (2003) Synthesis of Tri‐ and Tetracyclic Condensed Quinoxalin‐2‐ones Fused Across the C‐3−N‐4 Bond. European Journal of Organic Chemistry 2003:12, pages 2314-2326.
Crossref
Julien A Brown. (2000) Synthesis of N-aryl indole-2-carboxylates via an intramolecular palladium-catalysed annulation of didehydrophenylalanine derivatives. Tetrahedron Letters 41:10, pages 1623-1626.
Crossref
G. Pattenden, J. I. G. Cadogan & S. V. LeyG. Pattenden, J. I. G. Cadogan & S. V. Ley. 1997. Dictionary of Organic Compounds. Dictionary of Organic Compounds 164 172 .
Michael P. Groziak. 1996. 231 254 .
M. J. BEACH, R. HOPE, D. H. KLAUBERT & R. K. RUSSELL. (2010) ChemInform Abstract: Two Step Synthesis of Substituted Indolo(1,2‐a)quinoxalin‐6‐ones.. ChemInform 26:41.
Crossref

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