A Facile One-Pot Synthesis of 4-Hydroxy-3-methoxycarbonyl-2-methyl-2H-1,2-benzothiazine 1,1-Dioxide, A Key Intermediate in the Synthesis of Oxicam Anti-Inflammatory Agents

Norberto Manjarrez Departamento Sistemas Biológicos, Universidad Autónoma Metropolitana, Unidad Xochimilco, P. B. 23–181, México

Herminia I. Pérez Departamento Sistemas Biológicos, Universidad Autónoma Metropolitana, Unidad Xochimilco, P. B. 23–181, México

Aída Solís Departamento Sistemas Biológicos, Universidad Autónoma Metropolitana, Unidad Xochimilco, P. B. 23–181, México

Héctor Luna Departamento Sistemas Biológicos, Universidad Autónoma Metropolitana, Unidad Xochimilco, P. B. 23–181, México

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Moustafa A. Gouda, Belal H. M. Hussein & Yousery El-Said Sherif. (2017) Synthesis and medicinal importance of oxicams and their analogues. Synthetic Communications 47:19, pages 1709-1736.
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Moustafa A. Gouda. (2017) Overview of the synthetic routes of 2-alkyl-4-hydroxy-2H-1,2-benzothiazine-3-carboxamides-1,1-dioxides (oxicams) and their analogues. Synthetic Communications 47:17, pages 1527-1558.
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Waseeq A. Siddiqui, Saeed Ahmad, Islam Ullah Khan, Hamid Latif Siddiqui & George W. Weaver. (2007) Facile One‐Pot Synthesis of 4‐Hydroxy‐2‐methyl‐(2H)‐1,2‐benzothiazine‐3‐sulfonic Acid 1,1‐Dioxide. Synthetic Communications 37:5, pages 767-773.
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Yusuke OhtaYusuke Ohta. 2011. Copper-Catalyzed Multi-Component Reactions. Copper-Catalyzed Multi-Component Reactions 9 45 .

Yusuke OhtaHiroaki ChibaShinya OishiNobutaka FujiiHiroaki Ohno. (2009) Construction of Nitrogen Heterocycles Bearing an Aminomethyl Group by Copper-Catalyzed Domino Three-Component Coupling−Cyclization. The Journal of Organic Chemistry 74:18, pages 7052-7058.
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Waseeq Ahmad Siddiqui, Saeed Ahmad, Hamid Latif Siddiqui, Masood Parvez & Rehana Rashid. (2008) Methyl 3-oxo-2,3-dihydro-1,2-benzothiazole-2-acetate 1,1-dioxide. Acta Crystallographica Section E Structure Reports Online 64:5, pages o859-o859.
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Timothy D. Owens & J. Edward Semple. (1998) Alkoxide-catalyzed ring-opening of a novel homosaccharin derivative: synthesis of potent, selective P3-lactam thrombin inhibitors containing P4-o-alkoxycarbonylbenzylsulfonamide residues. Bioorganic & Medicinal Chemistry Letters 8:24, pages 3683-3688.
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N. MANJARREZ, H. I. PEREZ, A. SOLIS & H. LUNA. (2010) ChemInform Abstract: A Facile One‐Pot Synthesis of 4‐Hydroxy‐3‐methoxycarbonyl‐2‐methyl‐2H‐ 1,2‐benzothiazine 1,1‐Dioxide, a Key Intermediate in the Synthesis of Oxicam Anti‐Inflammatory Agents.. ChemInform 27:24.
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A Facile One-Pot Synthesis of 4-Hydroxy-3-methoxycarbonyl-2-methyl-2H-1,2-benzothiazine 1,1-Dioxide, A Key Intermediate in the Synthesis of Oxicam Anti-Inflammatory Agents

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A Facile One-Pot Synthesis of 4-Hydroxy-3-methoxycarbonyl-2-methyl-2H-1,2-benzothiazine 1,1-Dioxide, A Key Intermediate in the Synthesis of Oxicam Anti-Inflammatory Agents

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