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Synthetic Communications

An International Journal for Rapid Communication of Synthetic Organic Chemistry

Volume 27, 1997 - Issue 17

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Original Articles

The Preparation of Substituted 1(2H)-Isoquinolinones from Dilithiated 2-Methyl-N-arylbenzamides, 2-Methyl-N-(arylmethyl)-benzamides, or 2-Methylbenzoic Acid, 2,2-Dimethylhydrazide

Sharon E. Davis Department of Chemistry and Biochemistry, College of Charleston Charleston, South Carolina, 29424

A. Cameron Church Department of Chemistry and Biochemistry, College of Charleston Charleston, South Carolina, 29424

Cynthia L. Mazat Griffith Department of Chemistry and Biochemistry, College of Charleston Charleston, South Carolina, 29424

Charles F. Beam Department of Chemistry and Biochemistry, College of Charleston Charleston, South Carolina, 29424

Pages 2961-2969 | Received 21 Mar 1997, Published online: 22 Aug 2006

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https://doi.org/10.1080/00397919708005002

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Ruimao Hua. (2021) Isoquinolone Syntheses by Annulation Protocols. Catalysts 11:5, pages 620.
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Muhammad Shareef Mayo, Xiaoqiang Yu, Xiujuan Feng, Yoshinori Yamamoto & Ming Bao. (2015) Isoquinolone Synthesis through S N Ar Reaction of 2-Halobenzonitriles with Ketones Followed by Cyclization . The Journal of Organic Chemistry 80:8, pages 3998-4002.
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Wen-Tao Wei, Yu Liu, Lin-Miao Ye, Rong-Hui Lei, Xue-Jing Zhang & Ming Yan. (2015) Rapid synthesis of isoquinolinones by intramolecular coupling of amides and ketones. Organic & Biomolecular Chemistry 13:3, pages 817-824.
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William G. Shuler, Ellyn A. Smith, Sloan M. Hess, Thomas M. C. McFadden, Clyde R. Metz, Donald G. VanDerveer, William T. Pennington, Phillip J. Mabe, Shabree L. Knick & Charles F. Beam. (2012) Preparation and X-Ray Crystal Structure of 3-(4-(Dimethylamino)phenyl)-2-(phenylamino)isoquinolin-1(2H)-one, 3-(4-Methoxyphenyl)-2-(phenylamino)isoquinolin-1(2H)-one, and 2-Methyl-N′-(4-methylbenzoyl)-N′-phenylbenzohydrazide from Polylithiated 2-methylbenzoic Acid Phenylhydrazide and Methyl 4-dimethylaminobenzoate, Methyl 4-methoxybenzoate, or Methyl 4-methylbenzoate. Journal of Chemical Crystallography 42:9, pages 952-959.
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Varadhan Krishnakumar, Kesarla Mohan Kumar, Badal Kumar Mandal & Fazlur-Rahman Nawaz Khan. (2012) Zinc Oxide Nanoparticles Catalyzed Condensation Reaction of Isocoumarins and 1,7-Heptadiamine in the Formation of Bis-Isoquinolinones. The Scientific World Journal 2012, pages 1-7.
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Chuan-Che Liu, Kanniyappan Parthasarathy & Chien-Hong Cheng. (2010) Synthesis of Highly Substituted Isoquinolone Derivatives by Nickel-Catalyzed Annulation of 2-Halobenzamides with Alkynes. Organic Letters 12:15, pages 3518-3521.
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Feng Wang, Hongxia Liu, Hua Fu, Yuyang Jiang & Yufen Zhao. (2009) An Efficient One-Pot Copper-Catalyzed Approach to Isoquinolin-1(2 H )-one Derivatives . Organic Letters 11:11, pages 2469-2472.
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Martha L. Minich, Isa D. Watson, Kevin J. Filipski & Jeffrey A. Pfefferkorn. (2009) Novel and efficient synthesis of 4-sulfonyl-2-pyridones. Tetrahedron Letters 50:18, pages 2094-2096.
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Zhaoyan Zheng & Howard Alper. (2008) Palladium-Catalyzed Carbonylation−Decarboxylation of Diethyl(2-iodoaryl)malonates with Imidoyl Chlorides: An Efficient Route to Substituted Isoquinolin-1(2 H )-ones . Organic Letters 10:21, pages 4903-4906.
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M. Jain. 2003. Chemical Shifts and Coupling Constants for Hydrogen-1. Part 2: Heterocycles. Chemical Shifts and Coupling Constants for Hydrogen-1. Part 2: Heterocycles 174 204 .

M. Jain. 2003. Chemical Shifts and Coupling Constants for Hydrogen-1. Part 2: Heterocycles. Chemical Shifts and Coupling Constants for Hydrogen-1. Part 2: Heterocycles 346 370 .

Robert D. Larsen. 1998. A critical review of the 1997 literature preceded by two chapters on current heterocyclic topics. A critical review of the 1997 literature preceded by two chapters on current heterocyclic topics 226 250 .

S. E. DAVIS, A. C. CHURCH, C. L. GRIFFITH & C. F. BEAM. (2010) ChemInform Abstract: Preparation of Substituted 1(2H)‐Isoquinolinones (IV) from Dilithiated 2‐Methyl‐N‐arylbenzamides, 2‐Methyl‐N‐(arylmethyl)‐benzamides, or 2‐ Methylbenzoic Acid 2,2‐Dimethylhydrazide. ChemInform 28:47.
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The Preparation of Substituted 1(2H)-Isoquinolinones from Dilithiated 2-Methyl-N-arylbenzamides, 2-Methyl-N-(arylmethyl)-benzamides, or 2-Methylbenzoic Acid, 2,2-Dimethylhydrazide

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The Preparation of Substituted 1(2H)-Isoquinolinones from Dilithiated 2-Methyl-N-arylbenzamides, 2-Methyl-N-(arylmethyl)-benzamides, or 2-Methylbenzoic Acid, 2,2-Dimethylhydrazide

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