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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 29, 1999 - Issue 20
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Original Articles

Simple and Cost Effective Syntheses of 4-Hydroxycoumarin

Jae-Chul Jung Department of Chemistry, College of Natural Sciences, Chungbuk National University, Cheongju, 361-763, Chungbuk, Korea
,
Ju-Cheun Kim Department of Chemistry, College of Natural Sciences, Chungbuk National University, Cheongju, 361-763, Chungbuk, Korea
&
Oee-Sook Park Department of Chemistry, College of Natural Sciences, Chungbuk National University, Cheongju, 361-763, Chungbuk, Korea
Pages 3587-3595 | Received 19 Jan 1999, Published online: 17 Sep 2007

Citations (29)

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Read on this site (5)

G. D. Kotkar & S. G. Tilve. (2024) P4O10/TfOH-mediated metal-free synthesis of 4-hydroxycoumarins and a one-pot strategy to build their hybrids. Synthetic Communications 54:5, pages 379-389.
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Ahmed K. El-Ziaty, Wael S. I. Abou-Elmagd, Sayed K. Ramadan & Ahmed I. Hashem. (2017) Synthesis and biological screening of some chromonyl-substituted heterocycles derived from 2(3H)-furanone derivative. Synthetic Communications 47:5, pages 471-480.
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Wen-Tao Gao, Wen-Duan Hou, Mei-Ru Zheng & Li-Jun Tang. (2010) Clean and Convenient One-Pot Synthesis of 4-Hydroxycoumarin and 4-Hydroxy-2-quinolinone Derivatives. Synthetic Communications 40:5, pages 732-738.
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Antigoni Kotali, IoannisS. Lafazanis & PhilipA. Harris. (2008) Synthesis of 6,7-Diacylcoumarins via the Transformation of a Hydroxy into a Carbonyl Group. Synthetic Communications 38:22, pages 3996-4006.
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Jae-Chul Jung, Young-Jo Jung & Oee-Sook Park. (2001) A CONVENIENT ONE-POT SYNTHESIS OF 4-HYDROXYCOUMARIN, 4-HYDROXYTHIOCOUMARIN, AND 4-HYDROXYQUINOLIN-2(1H)-ONE. Synthetic Communications 31:8, pages 1195-1200.
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Articles from other publishers (24)

Yasameen K. Al-Majedy, Hiba H. Ibraheem & Ali Abdullah Issa. Antioxidant, antimicrobial activity and quantum chemical studies of 4-methyl-7-hyroxy coumarin derivatives. Antioxidant, antimicrobial activity and quantum chemical studies of 4-methyl-7-hyroxy coumarin derivatives.
P. Datta, D. Sardar, C. Sinha, A. Manna & M. Chatterjee. (2022) Structure and Cytotoxic Activity of Novel 2-(Coumarinyl-6-azo)imidazoles. Asian Journal of Chemistry 34:11, pages 3033-3036.
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S. Shaker, Y. K. Al-Majedy, H. H. Ibraheem & A.A. Al-Amiery. (2021) Synthesis and quantum chemical studies of methyl 2-(4-methyl-2-oxo-2h-chromen-7-yloxy) acetate derivatives. Journal of Physics: Conference Series 1795:1, pages 012029.
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Rabia Basri, Muhammad Khalid, Zahid Shafiq, Muhammad Suleman Tahir, Muhammad Usman Khan, Muhammad Nawaz Tahir, Muhammad Moazzam Naseer & Ataualpa Albert Carmo Braga. (2020) Exploration of Chromone-Based Thiosemicarbazone Derivatives: SC-XRD/DFT, Spectral (IR, UV–Vis) Characterization, and Quantum Chemical Analysis. ACS Omega 5:46, pages 30176-30188.
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Saleem Farooq, Aashiq Hussain, Mushtaq A. Qurishi, Abid Hamid & S. Koul. (2019) Synthesis and Biological Evaluation of Novel Triazoles Linked 7-hydroxycoumarin as Potent Cytotoxic Agents. Anti-Cancer Agents in Medicinal Chemistry 18:11, pages 1531-1539.
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Moaz M. Abdou, Rasha A. El-Saeed & Samir Bondock. (2019) Recent advances in 4-hydroxycoumarin chemistry. Part 1: Synthesis and reactions. Arabian Journal of Chemistry 12:1, pages 88-121.
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Moaz M. Abdou. (2017) 3-Acetyl-4-hydroxycoumarin: Synthesis, reactions and applications. Arabian Journal of Chemistry 10, pages S3664-S3675.
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Noraziah Nordin, Mehran Fadaeinasab, Syam Mohan, Najihah Mohd Hashim, Rozana Othman, Hamed Karimian, Venus Iman, Noorlela Ramli, Hapipah Mohd Ali & Nazia Abdul Majid. (2016) Pulchrin A, a New Natural Coumarin Derivative of Enicosanthellum pulchrum, Induces Apoptosis in Ovarian Cancer Cells via Intrinsic Pathway. PLOS ONE 11:5, pages e0154023.
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Mounir Salem, Magda Marzouk & Azza El-Kazak. (2016) Synthesis and Characterization of Some New Coumarins with in Vitro Antitumor and Antioxidant Activity and High Protective Effects against DNA Damage. Molecules 21:2, pages 249.
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Dian He, Jing Ma, Xiuxiao Shi, Chunyan Zhao, Meng Hou, Qingxin Guo, Shangxian Ma, Xiaojun Li, Peicheng Zhao, Wenhu Liu, Zhuqing Yang, Jianping Mou, Pengfei Song, Yang Zhang & Jing Li. (2014) Design, Synthesis, and Potent Antiepileptic Activity with Latent Nerve Rehabilitation of Novel γ-Aminobutyric Acid Derivatives. Chemical and Pharmaceutical Bulletin 62:10, pages 967-978.
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Pengfei Li, Jun Wang & Fuk Yee Kwong. 2015. Stereoselective Synthesis of Drugs and Natural Products. Stereoselective Synthesis of Drugs and Natural Products 1 22 .
Krešimir Benci, Leo Mandić, Tomislav Suhina, Mirela Sedić, Marko Klobučar, Sandra Kraljević Pavelić, Krešimir Pavelić, Karlo Wittine & Mladen Mintas. (2012) Novel Coumarin Derivatives Containing 1,2,4-Triazole, 4,5-Dicyanoimidazole and Purine Moieties: Synthesis and Evaluation of Their Cytostatic Activity. Molecules 17:9, pages 11010-11025.
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Samina Khan Yusufzai, Hasnah Osman, Aisyah Saad Abdul Rahim, Suhana Arshad & Ibrahim Abdul Razak. (2012) 3-(2-Methylamino-1,3-thiazol-4-yl)-2 H -chromen-2-one . Acta Crystallographica Section E Structure Reports Online 68:8, pages o2416-o2417.
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Redah I. Al-Bayati, Mahdi F. Radey & Ahmed A. Al-Amiery. (2012) Solvent-Free Synthesis of New Coumarins. Organic Chemistry International 2012, pages 1-8.
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Ahmed A. Al-Amiery, Redha I. H. Al-Bayati, Kawkab Y. Saour & Mahdi F. Radi. (2011) Cytotoxicity, antioxidant, and antimicrobial activities of novel 2-quinolone derivatives derived from coumarin. Research on Chemical Intermediates 38:2, pages 559-569.
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D. N. Bazhin, E. V. Schegol’kov, Yu. S. Kudyakova, Ya. V. Burgart & V. I. Saloutin. (2011) Structure of diethyl (polyfluorobenzoyl)malonates and their thermal intramolecular cyclization. Russian Chemical Bulletin 60:5, pages 929-932.
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Musiliyu A. Musa, John S. Cooperwood, M. Omar F. Khan & Taufiq Rahman. (2010) In‐vitro Antiproliferative Activity of Benzopyranone Derivatives in Comparison with Standard Chemotherapeutic Drugs . Archiv der Pharmazie 344:2, pages 102-110.
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Qi-Lun Liu, Qiu-Lian Li, Xiang-Dong Fei & Yong-Ming Zhu. (2010) Metal-Free Intramolecular Amination: One-Pot Tandem Synthesis of 3-Substituted 4-Quinolones. ACS Combinatorial Science 13:1, pages 19-23.
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Valentina Stefanou, Dimitris Matiadis, Georgia Melagraki, Antreas Afantitis, Giorgos Athanasellis, Olga Igglessi-Markopoulou, Vickie McKee & John Markopoulos. (2011) Functionalized 4-Hydroxy Coumarins: Novel Synthesis, Crystal Structure and DFT Calculations. Molecules 16:1, pages 384-402.
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Jae-Chul Jung, Soyong Jang, Seikwan Oh & Oee-Sook Park. (2010) Simple synthesis and biological evaluation of flocoumafen and its structural isomers. Journal of Chemical Sciences 122:6, pages 833-838.
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Tor E. Kristensen, Kristian Vestli, Finn K. Hansen & Tore Hansen. (2009) New Phenylglycine‐Derived Primary Amine Organocatalysts for the Preparation of Optically Active Warfarin. European Journal of Organic Chemistry 2009:30, pages 5185-5191.
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Jae-Chul Jung, E.Blake Watkins & Mitchell A Avery. (2002) Synthesis of 3-substituted and 3,4-disubstituted pyrazolin-5-ones. Tetrahedron 58:18, pages 3639-3646.
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Jae‐Chul Jung, Young‐Jo Jung & Oee‐Sook Park. (2009) Synthesis of 4‐hydroxyquinolin‐2(1 H )‐one analogues and 2‐substituted quinolone derivatives . Journal of Heterocyclic Chemistry 38:1, pages 61-67.
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Jae‐Chul Jung, Ju‐Cheun Kim & Oee‐Sook Park. (2010) ChemInform Abstract: Simple and Cost Effective Syntheses of 4‐Hydroxycoumarin.. ChemInform 30:48.
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